thiotepa has been researched along with Recrudescence in 72 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiotepa, busulfan and cyclophosphamide-based intensive chemotherapy is an effective treatment for refractory and recurrent primary central nervous system lymphoma in chemosensitive patients up to 65 years of age." | 9.16 | Intensive chemotherapy with thiotepa, busulfan and cyclophosphamide and hematopoietic stem cell rescue in relapsed or refractory primary central nervous system lymphoma and intraocular lymphoma: a retrospective study of 79 cases. ( Bouabdallah, K; Choquet, S; Damaj, G; Delgadillo, D; Dupriez, B; Fourme, E; Ghesquières, H; Gonzalez, A; Hoang-Xuan, K; Houillier, C; Leblond, V; Soussain, C; Taillandier, L; Vargaftig, J, 2012) |
| "Thirty-four adults with malignant lymphoma at high-risk for relapse were treated on a Phase I-II study of high-dose thiotepa (THIO), busulfan (BU) and cyclophosphamide (CYC) with autologous marrow or peripheral blood stem cell support." | 9.08 | A phase I-II study of high-dose thiotepa, busulfan and cyclophosphamide as a preparative regimen for autologous transplantation for malignant lymphoma. ( Diener, K; Dimopoulos, M; Giralt, S; Hagemeister, F; Ippoliti, C; Khouri, I; Mehra, R; Nath, R; Przepiorka, D; Samuels, B, 1995) |
| " Topical Mitomycin caused: iritis, conjunctival irritation, excessive lacrymation, photophobia, ocular pain; Thio-tepa caused: photophobia, foreign body sensation, headache." | 9.08 | [A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results]. ( Kayembe, L; Ngoy, D, 1998) |
| "To analyze effectiveness and side effects of thiotepa eyedrops utilized to prevent postoperative pterygium recurrence, with a retrospective study allowing a long follow-up." | 7.70 | [Thiotepa eyedrops for prevention of pterygium recurrence: 18 years of use]. ( Ribe, D; Tassy, A, 1999) |
| "Thiotepa, busulfan and cyclophosphamide-based intensive chemotherapy is an effective treatment for refractory and recurrent primary central nervous system lymphoma in chemosensitive patients up to 65 years of age." | 5.16 | Intensive chemotherapy with thiotepa, busulfan and cyclophosphamide and hematopoietic stem cell rescue in relapsed or refractory primary central nervous system lymphoma and intraocular lymphoma: a retrospective study of 79 cases. ( Bouabdallah, K; Choquet, S; Damaj, G; Delgadillo, D; Dupriez, B; Fourme, E; Ghesquières, H; Gonzalez, A; Hoang-Xuan, K; Houillier, C; Leblond, V; Soussain, C; Taillandier, L; Vargaftig, J, 2012) |
| "Thirty-four adults with malignant lymphoma at high-risk for relapse were treated on a Phase I-II study of high-dose thiotepa (THIO), busulfan (BU) and cyclophosphamide (CYC) with autologous marrow or peripheral blood stem cell support." | 5.08 | A phase I-II study of high-dose thiotepa, busulfan and cyclophosphamide as a preparative regimen for autologous transplantation for malignant lymphoma. ( Diener, K; Dimopoulos, M; Giralt, S; Hagemeister, F; Ippoliti, C; Khouri, I; Mehra, R; Nath, R; Przepiorka, D; Samuels, B, 1995) |
| " Topical Mitomycin caused: iritis, conjunctival irritation, excessive lacrymation, photophobia, ocular pain; Thio-tepa caused: photophobia, foreign body sensation, headache." | 5.08 | [A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results]. ( Kayembe, L; Ngoy, D, 1998) |
| " Graft-versus-host disease prophylaxis consisted of cyclosporine A and alemtuzumab (10-20 mg)." | 3.78 | Radiation-free allogeneic conditioning with fludarabine, carmustine, and thiotepa for acute lymphoblastic leukemia and other hematologic malignancies necessitating enhanced central nervous system activity. ( Bertz, H; Christopoulos, P; Finke, J; Ihorst, G; Marks, R; Wäsch, R, 2012) |
| " In order to decrease nonrelapse mortality, and enhance the graft-versus-tumor effect, a program was designed in which a reduced conditioning with thiotepa, fludarabine, and cyclophosphamide was associated with programmed reinfusions of donor lymphocytes for patients without graft-versus-host disease (GVHD), not achieving clinical and molecular remission after transplantation." | 3.71 | Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies. ( Benedetti, F; Bordignon, C; Bregni, M; Ciceri, F; Corradini, P; Dodero, A; Falda, M; Gianni, AM; Ladetto, M; Lucesole, M; Olivieri, A; Pileri, A; Rambaldi, A; Sajeva, MR; Tarella, C; Tresoldi, M; Voena, C; Zallio, F, 2002) |
| "To analyze effectiveness and side effects of thiotepa eyedrops utilized to prevent postoperative pterygium recurrence, with a retrospective study allowing a long follow-up." | 3.70 | [Thiotepa eyedrops for prevention of pterygium recurrence: 18 years of use]. ( Ribe, D; Tassy, A, 1999) |
| " The following protocols are proposed: CIRP (colchicine in recurrent pericarditis)--colchicine vs placebo in chronic/recurring pericarditis without pericardiocentesis; TRIPE (triamcinolone in pericardial effusion)--intrapericardial instillation of triamcinolone + 6 months colchicine vs pericardial puncture without instillation + 6 months colchicine; NEPIN (neoplastic effusion and pericardial instillation)--pericardiocentesis and drainage + intrapericardial instillation of cisplatin or thiotepa." | 3.70 | New directions in diagnosis and treatment of pericardial disease. A project of the Taskforce on Pericardial Disease of the World Heart Federation. ( Maisch, B; Ristić, AD; Seferovic, PM, 2000) |
| "Diagnoses were AML (n=18), ALL (n=3), multiple myeloma (n=11), lymphoma (n=16) and CML (n=1)." | 2.73 | A fludarabine, thiotepa reduced toxicity conditioning regimen designed specifically for allogeneic second haematopoietic cell transplantation after failure of previous autologous or allogeneic transplantation. ( Bertz, H; Finke, J; Grüllich, C; Müller, CI; Spyridonidis, A, 2008) |
| "Thiotepa has excellent antileukemic and immunosuppressive activity, and could therefore be a useful drug in the conditioning regimen for patients with advanced hematologic neoplasms." | 2.71 | Thiotepa and fractionated TBI conditioning prior to allogeneic stem cell transplantation for advanced hematologic malignancies: a phase II single institution trial. ( Beall, CL; Bunner, P; Devetten, MP; Ericson, SG; Lynch, JP; Qazilbash, MH; Weisenborn, R, 2004) |
| "One hundred women with metastatic breast cancer (MBC) underwent high-dose chemotherapy with autologous stem cell rescue at our institution beginning in 1986." | 2.69 | High-dose chemotherapy consolidation with autologous stem cell rescue in metastatic breast cancer: a 10-year experience. ( Bitran, JD; Grad, G; Grinblatt, DL; Laport, GF; Williams, SF, 1998) |
| "Nineteen breast cancer patients underwent autotransplants exclusively using ex vivo expanded small aliquot BM cells (900-1200 x 10(6))." | 2.69 | Autologous transplantation of ex vivo expanded bone marrow cells grown from small aliquots after high-dose chemotherapy for breast cancer. ( Armstrong, RD; Bayer, R; Chen, B; Douville, J; Franklin, W; Hsi, E; Malhotra, D; Mandalam, R; Muller, T; Oldenberg, D; Shpall, E; Smith, A; Stiff, P, 2000) |
| "Because distant visceral metastases still remain a major site of failure after this HDC regimen, a more effective systemic therapy is needed." | 2.68 | Patterns of failure following bone marrow transplantation for metastatic breast cancer: the role of consolidative local therapy. ( Ghalie, R; Hartsell, WF; Kaizer, H; Shah, AB, 1995) |
| "Optimal conditioning for adults with acute lymphoblastic leukemia (ALL) treated with haploidentical hematopoietic cell transplantation (haplo-HCT) and post-transplant cyclophosphamide has not been established so far." | 1.72 | Total body irradiation plus fludarabine versus thiotepa, busulfan plus fludarabine as a myeloablative conditioning for adults with acute lymphoblastic leukemia treated with haploidentical hematopoietic cell transplantation. A study by the Acute Leukemia W ( Aljurf, M; Angelucci, E; Arat, M; Bernasconi, P; Giebel, S; Labopin, M; Mohty, M; Nagler, A; Pavlu, J; Peric, Z; Pioltelli, P; Rigacci, L; Risitano, A; Rovira, M; Saccardi, R; Savani, BN; Sica, S; Socié, G; Spyridonidis, A; Swoboda, R; Tischer, J; Van Gorkom, G; Vitek, A, 2022) |
| "Patients with Gilbert's syndrome were defined as having laboratory values before the start of conditioning therapy for unconjugated serum bilirubin concentrations of at least 17·1 μmol/L (≥1 mg/dL), normal conjugated serum bilirubin, and no evidence of hepatitis, cholestasis, or haemolysis." | 1.43 | Mortality outcomes after busulfan-containing conditioning treatment and haemopoietic cell transplantation in patients with Gilbert's syndrome: a retrospective cohort study. ( Evans, AT; Gooley, TA; McCune, JS; McDonald, GB; Ostrow, JD; Schoch, G, 2016) |
| "Clofarabine was administered at a dose of 30 or 40 mg/m(2)/day over 2 hr for five consecutive days in six patients each." | 1.36 | Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia. ( Kobos, R; Shukla, N; Steinherz, L; Steinherz, PG, 2010) |
| " TMJ is a safe and effective regimen when used as a part of autologous stem cell transplant for patients with HD and NHL." | 1.32 | High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors. ( Ahmed, T; Hoang, A; Kancherla, R; Liu, D; Qureshi, Z; Seiter, K; Waheed, F, 2004) |
| "Patients with breast cancer as their primary malignancy survived significantly longer after drainage than did all others (p = 0." | 1.30 | Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions. ( Burt, ME; Ginsberg, RJ; Girardi, LN, 1997) |
| "The prognosis in patients with primary brain tumors treated with surgery, radiotherapy and conventional chemotherapy remains poor." | 1.30 | High-dose thiotepa and etoposide-based regimens with autologous hematopoietic support for high-risk or recurrent CNS tumors in children and adults. ( Antman, KH; Bagiella, E; Balmaceda, C; Bruce, J; De LaPaz, R; Fetell, M; Garrett, TJ; Garvin, JH; Hawks, R; Hesdorffer, CS; Isaacson, S; Papadopoulos, KP; Savage, DG; Sisti, M; Vahdat, LT, 1998) |
| " When beta-radiation or Thiotepa is used there is a general consensus on the dosage for each of these." | 1.28 | Treatment of pterygia in Queensland. ( Hirst, LW; Sebban, A, 1991) |
| "The difference in the recurrence rate between the eyes submitted to Beta therapy and those not submitted is considered statistically significant." | 1.27 | Pterygium and beta irradiation. ( Barishak, YR; Monselise, M; Politi, F; Schwartz, M, 1984) |
| "Guidelines for the treatment of pterygium are recommended." | 1.26 | The management of pterygium. ( Ehrlich, D, 1977) |
| "In order to reduce the recurrence rate of bladder tumours, 78 patients with bladder tumours have been treated since November 1973 with topical Thio-TEPA bladder instillations." | 1.26 | The prophylactic use of Thio-TEPA, an adjuvant in the treatment of bladder tumours. ( Dobrzecki, W; Kaczmarek, A, 1977) |
| "Studies on the effect of different regimens of chemotherapy and local x-ray irradiation on the kinetics of the growth of Walker carcinosarcoma and Heren carcinoma have demonstrated that in the range of dosage of alkylating action drugs under study and also irradiation, the time of the recurrence onset depends on the therapeutic regimen." | 1.25 | [Effect of different regimens of chemotherapy and x-ray irradiation on the kinetics of experimental tumor growth]. ( Emanuél', NM; Konovalova, NP; Parkanskiĭ, MI, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (23.61) | 18.7374 |
| 1990's | 17 (23.61) | 18.2507 |
| 2000's | 15 (20.83) | 29.6817 |
| 2010's | 18 (25.00) | 24.3611 |
| 2020's | 5 (6.94) | 2.80 |
| Authors | Studies |
|---|---|
| Ramaswamy, K | 1 |
| Steinherz, PG | 4 |
| Agrawal, AK | 1 |
| Forlenza, CJ | 1 |
| Mauguen, A | 1 |
| Roshal, M | 1 |
| Trippett, T | 1 |
| Kernan, NA | 2 |
| Sulis, ML | 1 |
| Shukla, N | 3 |
| Swoboda, R | 1 |
| Labopin, M | 3 |
| Giebel, S | 2 |
| Angelucci, E | 2 |
| Arat, M | 1 |
| Aljurf, M | 2 |
| Sica, S | 1 |
| Pavlu, J | 1 |
| Socié, G | 2 |
| Bernasconi, P | 3 |
| Rigacci, L | 1 |
| Tischer, J | 1 |
| Risitano, A | 1 |
| Rovira, M | 1 |
| Saccardi, R | 1 |
| Pioltelli, P | 1 |
| Van Gorkom, G | 1 |
| Vitek, A | 1 |
| Savani, BN | 1 |
| Spyridonidis, A | 2 |
| Peric, Z | 1 |
| Nagler, A | 3 |
| Mohty, M | 3 |
| Bonifazi, F | 2 |
| Pavoni, C | 2 |
| Peccatori, J | 1 |
| Giglio, F | 1 |
| Arpinati, M | 1 |
| Busca, A | 1 |
| Grassi, A | 1 |
| Iori, AP | 1 |
| Patriarca, F | 2 |
| Brunello, L | 1 |
| Di Grazia, C | 1 |
| Carella, AM | 2 |
| Cilloni, D | 1 |
| Picardi, A | 2 |
| Proia, A | 1 |
| Santarone, S | 2 |
| Sorasio, R | 1 |
| Carluccio, P | 1 |
| Chiusolo, P | 1 |
| Cupri, A | 1 |
| Luppi, M | 1 |
| Nozzoli, C | 1 |
| Baronciani, D | 2 |
| Casini, M | 1 |
| Grillo, G | 1 |
| Musso, M | 1 |
| Onida, F | 1 |
| Palazzo, G | 1 |
| Parma, M | 1 |
| Tringali, S | 1 |
| Vacca, A | 1 |
| Vallisa, D | 1 |
| Sacchi, N | 1 |
| Oldani, E | 1 |
| Masciulli, A | 2 |
| Gheorghiu, A | 1 |
| Girmenia, C | 1 |
| Martino, M | 1 |
| Bruno, B | 3 |
| Rambaldi, A | 4 |
| Ciceri, F | 2 |
| Luo, C | 1 |
| Wu, G | 1 |
| Huang, X | 1 |
| Ding, Y | 1 |
| Huang, Y | 1 |
| Song, Q | 1 |
| Hou, Y | 1 |
| Chen, J | 2 |
| Li, X | 1 |
| Xu, S | 1 |
| Arshad, S | 1 |
| Fang, X | 1 |
| Ahn, KW | 1 |
| Kaur, M | 1 |
| Scordo, M | 1 |
| Sauter, CS | 1 |
| Furqan, F | 1 |
| Awan, FT | 1 |
| Hamadani, M | 1 |
| Eder, S | 2 |
| Canaani, J | 1 |
| Beohou, E | 1 |
| Sanz, J | 2 |
| Arcese, W | 2 |
| Or, R | 2 |
| Finke, J | 6 |
| Cortelezzi, A | 1 |
| Beelen, D | 1 |
| Passweg, J | 1 |
| Gurman, G | 1 |
| Stelljes, M | 1 |
| Sheth, V | 1 |
| Nachmias, B | 1 |
| Grisariu, S | 1 |
| Avni, B | 1 |
| Shapira, M | 1 |
| Bacigalupo, A | 1 |
| Bregante, S | 1 |
| Finazzi, MC | 1 |
| Bosi, A | 1 |
| Russo, D | 1 |
| Narni, F | 1 |
| Messina, G | 2 |
| Alessandrino, EP | 2 |
| Milone, G | 1 |
| Mammoliti, S | 1 |
| Fanin, R | 1 |
| Wawrzyniak-Dzierżek, E | 1 |
| Gajek, K | 1 |
| Rybka, B | 1 |
| Ryczan-Krawczyk, R | 1 |
| Węcławek-Tompol, J | 1 |
| Raciborska, A | 1 |
| Mielcarek-Siedziuk, M | 1 |
| Frączkiewicz, J | 1 |
| Salamonowicz, M | 1 |
| Kałwak, K | 1 |
| Rosa, M | 1 |
| Ślęzak, A | 1 |
| Ussowicz, M | 1 |
| Bayraktar, UD | 1 |
| de Lima, M | 1 |
| Saliba, RM | 1 |
| Maloy, M | 1 |
| Castro-Malaspina, HR | 1 |
| Rondon, G | 1 |
| Chiattone, A | 1 |
| Jakubowski, AA | 1 |
| Boulad, F | 1 |
| O'Reilly, RJ | 1 |
| Champlin, RE | 1 |
| Giralt, S | 3 |
| Andersson, BS | 2 |
| Papadopoulos, EB | 1 |
| Baetschmann, G | 1 |
| Winkelmann, R | 1 |
| Kobos, R | 2 |
| Renaud, T | 1 |
| Steinherz, LJ | 1 |
| Depau, C | 1 |
| Targhetta, C | 1 |
| Derudas, D | 1 |
| Culurgioni, F | 1 |
| Tandurella, I | 1 |
| Latte, G | 1 |
| Palmas, A | 1 |
| Srour, SA | 1 |
| Borders, EB | 1 |
| Cherry, MA | 1 |
| Holter, J | 1 |
| Herman, T | 1 |
| Selby, GB | 1 |
| Piñana, JL | 1 |
| Esquirol, A | 1 |
| Martino, R | 1 |
| Barba, P | 1 |
| Parody, R | 1 |
| Gayoso, J | 1 |
| Montesinos, P | 1 |
| Guidi, S | 1 |
| Terol, MJ | 1 |
| Moscardó, F | 1 |
| Solano, C | 1 |
| Sanz, MA | 1 |
| Sierra, J | 1 |
| Sanz, G | 1 |
| Bunjes, D | 1 |
| Olivieri, A | 2 |
| Kanz, L | 1 |
| McDonald, GB | 1 |
| Evans, AT | 1 |
| McCune, JS | 1 |
| Schoch, G | 1 |
| Ostrow, JD | 1 |
| Gooley, TA | 1 |
| Steinherz, L | 1 |
| Park, ES | 1 |
| Sung, KW | 1 |
| Baek, HJ | 1 |
| Park, KD | 1 |
| Park, HJ | 1 |
| Won, SC | 1 |
| Lim, DH | 1 |
| Kim, HS | 1 |
| Christopoulos, P | 2 |
| Bertz, H | 3 |
| Ihorst, G | 1 |
| Marks, R | 2 |
| Wäsch, R | 2 |
| Kasenda, B | 1 |
| Schorb, E | 1 |
| Fritsch, K | 1 |
| Illerhaus, G | 1 |
| Soussain, C | 2 |
| Choquet, S | 1 |
| Fourme, E | 1 |
| Delgadillo, D | 1 |
| Bouabdallah, K | 1 |
| Ghesquières, H | 1 |
| Damaj, G | 1 |
| Dupriez, B | 1 |
| Vargaftig, J | 1 |
| Gonzalez, A | 1 |
| Houillier, C | 1 |
| Taillandier, L | 1 |
| Hoang-Xuan, K | 2 |
| Leblond, V | 1 |
| Schmoor, C | 1 |
| Waterhouse, M | 1 |
| Zia, MI | 1 |
| Forsyth, P | 1 |
| Chaudhry, A | 1 |
| Russell, J | 1 |
| Stewart, DA | 1 |
| Anderson Penno, E | 1 |
| Braun, DA | 1 |
| Kamal, A | 1 |
| Hamilton, WK | 1 |
| Gimbel, HV | 1 |
| MEACHAM, CT | 1 |
| Kolb, EA | 1 |
| Levy, V | 1 |
| Devetten, MP | 1 |
| Qazilbash, MH | 1 |
| Beall, CL | 1 |
| Bunner, P | 1 |
| Weisenborn, R | 1 |
| Lynch, JP | 1 |
| Ericson, SG | 1 |
| Waheed, F | 1 |
| Kancherla, R | 2 |
| Seiter, K | 3 |
| Liu, D | 1 |
| Qureshi, Z | 1 |
| Hoang, A | 1 |
| Ahmed, T | 3 |
| Colombo, AA | 1 |
| Caldera, D | 1 |
| Malcovati, L | 1 |
| Troletti, D | 1 |
| Vanelli, L | 1 |
| Varettoni, M | 1 |
| Montanari, F | 1 |
| Lazzarino, M | 1 |
| Joselson, GA | 1 |
| Muller, P | 1 |
| Beske, F | 1 |
| Modrow, S | 1 |
| Sörensen, J | 1 |
| Schmidt, H | 1 |
| Kriener, S | 1 |
| Allwinn, R | 1 |
| Klingebiel, T | 1 |
| Schwabe, D | 1 |
| Lehrnbecher, T | 1 |
| Grüllich, C | 1 |
| Müller, CI | 1 |
| Hiwarkar, P | 1 |
| Arkenau, HT | 1 |
| Treleaven, J | 1 |
| Morgan, G | 1 |
| Potter, M | 1 |
| Ethell, M | 1 |
| Gourcuff, A | 1 |
| Tassy, A | 2 |
| Garron, J | 1 |
| Perruchot, PJ | 1 |
| Blondel, P | 1 |
| Monselise, M | 1 |
| Schwartz, M | 1 |
| Politi, F | 1 |
| Barishak, YR | 1 |
| Przepiorka, D | 3 |
| Nath, R | 2 |
| Ippoliti, C | 1 |
| Mehra, R | 3 |
| Hagemeister, F | 1 |
| Diener, K | 1 |
| Dimopoulos, M | 1 |
| Khouri, I | 2 |
| Samuels, B | 1 |
| Shah, AB | 1 |
| Hartsell, WF | 1 |
| Ghalie, R | 1 |
| Kaizer, H | 1 |
| van Besien, KW | 1 |
| Khouri, IF | 1 |
| Giralt, SA | 1 |
| McCarthy, P | 1 |
| Gajewski, JL | 1 |
| Bellare, N | 1 |
| Lake, D | 1 |
| Feldman, E | 1 |
| Helson, L | 2 |
| Mittelman, A | 2 |
| Puccio, C | 1 |
| Chun, H | 1 |
| Grima, K | 1 |
| Akhtar, T | 2 |
| Lake, DE | 1 |
| Beer, M | 1 |
| Feldman, EJ | 1 |
| Preti, RA | 1 |
| Ascensao, J | 1 |
| Cook, P | 1 |
| Goldberg, R | 1 |
| Coleman, M | 1 |
| Fontelonga, A | 1 |
| Kelly, AJ | 1 |
| MacKintosh, FR | 1 |
| Hall, S | 1 |
| Monroe, P | 1 |
| Wilson, GS | 1 |
| Shaft, D | 1 |
| Ruthven, A | 1 |
| Ascensao, JL | 1 |
| van Besien, K | 1 |
| Thall, P | 1 |
| Korbling, M | 1 |
| Pugh, WC | 1 |
| Anderlini, P | 1 |
| Amin, K | 1 |
| Mirza, N | 1 |
| Seong, D | 1 |
| Gajewski, J | 1 |
| Hester, J | 1 |
| Andersson, B | 1 |
| Cabanillas, F | 1 |
| Champlin, R | 1 |
| Girardi, LN | 1 |
| Ginsberg, RJ | 1 |
| Burt, ME | 1 |
| Laport, GF | 1 |
| Grad, G | 1 |
| Grinblatt, DL | 1 |
| Bitran, JD | 2 |
| Williams, SF | 2 |
| Kleta, R | 1 |
| Wagner, A | 1 |
| Jürgens, H | 1 |
| Ngoy, D | 1 |
| Kayembe, L | 1 |
| Papadopoulos, KP | 1 |
| Garvin, JH | 1 |
| Fetell, M | 1 |
| Vahdat, LT | 1 |
| Garrett, TJ | 1 |
| Savage, DG | 1 |
| Balmaceda, C | 1 |
| Bruce, J | 1 |
| Sisti, M | 1 |
| Isaacson, S | 1 |
| De LaPaz, R | 1 |
| Hawks, R | 1 |
| Bagiella, E | 1 |
| Antman, KH | 1 |
| Hesdorffer, CS | 1 |
| Ribe, D | 1 |
| Hu, WW | 1 |
| Long, GD | 1 |
| Stockerl-Goldstein, KE | 1 |
| Johnston, LJ | 1 |
| Chao, NJ | 1 |
| Negrin, RS | 1 |
| Blume, KG | 1 |
| Rick, O | 1 |
| Siegert, W | 1 |
| Beyer, J | 1 |
| Stiff, P | 1 |
| Chen, B | 1 |
| Franklin, W | 1 |
| Oldenberg, D | 1 |
| Hsi, E | 1 |
| Bayer, R | 1 |
| Shpall, E | 1 |
| Douville, J | 1 |
| Mandalam, R | 1 |
| Malhotra, D | 1 |
| Muller, T | 1 |
| Armstrong, RD | 1 |
| Smith, A | 1 |
| Ghosh, D | 1 |
| Lin, DY | 1 |
| Maisch, B | 1 |
| Ristić, AD | 1 |
| Seferovic, PM | 1 |
| Hertzberg, H | 1 |
| Kremens, B | 1 |
| Velten, I | 1 |
| Beck, JD | 1 |
| Greil, J | 1 |
| Corradini, P | 1 |
| Tarella, C | 1 |
| Gianni, AM | 1 |
| Voena, C | 1 |
| Zallio, F | 1 |
| Ladetto, M | 1 |
| Falda, M | 1 |
| Lucesole, M | 1 |
| Dodero, A | 1 |
| Benedetti, F | 1 |
| Sajeva, MR | 1 |
| Tresoldi, M | 1 |
| Pileri, A | 1 |
| Bordignon, C | 1 |
| Bregni, M | 1 |
| Edsmyr, F | 1 |
| Andersson, L | 1 |
| Olander, K | 1 |
| Haik, KG | 1 |
| Haik, GM | 1 |
| Pavone-Macaluso, M | 1 |
| Serlin, O | 1 |
| Keehn, RJ | 1 |
| Higgins, GA | 1 |
| Harrower, HW | 1 |
| Mendeloff, GL | 1 |
| Ehrlich, D | 1 |
| O'Dea, MJ | 1 |
| Malek, RS | 1 |
| Farrow, GM | 1 |
| Dobrzecki, W | 1 |
| Kaczmarek, A | 1 |
| Nieh, PT | 1 |
| Daly, JJ | 1 |
| Heaney, JA | 1 |
| Heney, NM | 1 |
| Prout, GR | 1 |
| Parkanskiĭ, MI | 1 |
| Konovalova, NP | 1 |
| Emanuél', NM | 1 |
| Schmidt, JD | 1 |
| Jacobo, EC | 1 |
| Weinstein, SH | 1 |
| Sebban, A | 1 |
| Hirst, LW | 1 |
| Moormeier, J | 1 |
| Mick, R | 1 |
| Dretler, SP | 1 |
| Bredin, HC | 1 |
| Asregadoo, ER | 1 |
| Swierzowa, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| High-dose Chemotherapy and Autologous Stem Cell Transplant or Consolidating Conventional Chemotherapy in Primary CNS Lymphoma - Randomized Phase III Trial[NCT02531841] | Phase 3 | 250 participants (Anticipated) | Interventional | 2014-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thiotepa and Recrudescence
| Article | Year |
|---|---|
Myeloablative conditioning regimens in adult patients with acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation in complete remission: a systematic review and network meta-analysis.
Topics: Adult; Bayes Theorem; Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematopoietic Stem Cell Tra | 2023 |
Management of pterygia: should thiotepa be used?
Topics: Animals; Humans; Pigmentation Disorders; Pterygium; Recurrence; Sunlight; Thiotepa | 1978 |
23 trials available for thiotepa and Recrudescence
| Article | Year |
|---|---|
Myeloablative conditioning with thiotepa-busulfan-fludarabine does not improve the outcome of patients transplanted with active leukemia: final results of the GITMO prospective trial GANDALF-01.
Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Prospect | 2022 |
Busulfan- or Thiotepa-Based Conditioning in Myelofibrosis: A Phase II Multicenter Randomized Study from the GITMO Group.
Topics: Adult; Blood Donors; Busulfan; Female; Follow-Up Studies; Graft Survival; Hematopoietic Stem Cell Tr | 2019 |
Feasibility and Safety of Treosulfan, Melphalan, and Thiotepa-Based Megachemotherapy with Autologous or Allogeneic Stem Cell Transplantation in Heavily Pretreated Children with Relapsed or Refractory Neuroblastoma.
Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Autografts; Busulfan; Child; Child, Pres | 2019 |
Phase II trial of clofarabine with topotecan, vinorelbine, and thiotepa in pediatric patients with relapsed or refractory acute leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucle | 2014 |
Treosulfan-fludarabine-thiotepa conditioning before allogeneic haemopoietic stem cell transplantation for patients with advanced lympho-proliferative disease. A single centre study.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Disease-Free Survival; Fema | 2016 |
Umbilical cord blood transplantation in adults with advanced hodgkin's disease: high incidence of post-transplant lymphoproliferative disease.
Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Chronic Disease; Cord Blood Stem Cell Transpla | 2016 |
Safety and efficacy of thiotepa-based conditioning for allogeneic transplantation in AML: a survey from the ALWP of the EBMT.
Topics: Adolescent; Adult; Aged; Allografts; Disease-Free Survival; Female; Graft vs Host Disease; Humans; L | 2017 |
Tandem high-dose chemotherapy and autologous stem cell transplantation in young children with atypical teratoid/rhabdoid tumor of the central nervous system.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child | 2012 |
Intensive chemotherapy with thiotepa, busulfan and cyclophosphamide and hematopoietic stem cell rescue in relapsed or refractory primary central nervous system lymphoma and intraocular lymphoma: a retrospective study of 79 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neopla | 2012 |
A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pres | 2003 |
Thiotepa and fractionated TBI conditioning prior to allogeneic stem cell transplantation for advanced hematologic malignancies: a phase II single institution trial.
Topics: Acute Disease; Adult; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Female; Graft vs | 2004 |
Reduced-intensity conditioning regimen with thiotepa and fludarabine followed by allogeneic blood stem cell transplantation in haematological malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Female; Graft | 2004 |
A fludarabine, thiotepa reduced toxicity conditioning regimen designed specifically for allogeneic second haematopoietic cell transplantation after failure of previous autologous or allogeneic transplantation.
Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neo | 2008 |
A phase I-II study of high-dose thiotepa, busulfan and cyclophosphamide as a preparative regimen for autologous transplantation for malignant lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Chemic | 1995 |
Patterns of failure following bone marrow transplantation for metastatic breast cancer: the role of consolidative local therapy.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantati | 1995 |
Single and double autotransplants for relapsing/refractory Hodgkin's disease: results of two consecutive trials.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carb | 1997 |
A novel high-dose chemotherapy protocol with autologous hematopoietic rescue in patients with metastatic breast cancer or recurrent non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1997 |
Allogeneic transplantation for recurrent or refractory non-Hodgkin's lymphoma with poor prognostic features after conditioning with thiotepa, busulfan, and cyclophosphamide: experience in 44 consecutive patients.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Disease-Free Survival; Drug Therapy, | 1997 |
High-dose chemotherapy consolidation with autologous stem cell rescue in metastatic breast cancer: a 10-year experience.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1998 |
[A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results].
Topics: Administration, Topical; Adult; Aged; Alkylating Agents; Conjunctiva; Cost-Benefit Analysis; Drug Co | 1998 |
A feasibility study of multiple cycle therapy with melphalan, thiotepa, and paclitaxel followed by mitoxantrone, thiotepa, and paclitaxel with autologous hematopoietic cell support for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Feasibility Studies; Female | 1999 |
Autologous transplantation of ex vivo expanded bone marrow cells grown from small aliquots after high-dose chemotherapy for breast cancer.
Topics: Adult; Antigens, CD34; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone M | 2000 |
Factors related to survival following resection for gastric carcinoma: analysis of 903 cases.
Topics: Adult; Aged; Clinical Trials as Topic; Floxuridine; Humans; Male; Middle Aged; Prognosis; Recurrence | 1977 |
47 other studies available for thiotepa and Recrudescence
| Article | Year |
|---|---|
Clofarabine with topotecan, vinorelbine, and thiotepa reinduction regimen for children and young adults with relapsed AML.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Clofarabine; Humans; Leukemia | 2022 |
Total body irradiation plus fludarabine versus thiotepa, busulfan plus fludarabine as a myeloablative conditioning for adults with acute lymphoblastic leukemia treated with haploidentical hematopoietic cell transplantation. A study by the Acute Leukemia W
Topics: Adult; Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, M | 2022 |
Impact of thiotepa dose-intensity in primary diffuse large B-cell lymphoma of the central nervous system undergoing autologous hematopoietic cell transplant with thiotepa/carmustine conditioning.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Autografts; Carmustine; Central Nervous Syste | 2023 |
Thiotepa-based conditioning versus total body irradiation as myeloablative conditioning prior to allogeneic stem cell transplantation for acute lymphoblastic leukemia: A matched-pair analysis from the Acute Leukemia Working Party of the European Society f
Topics: Adolescent; Adult; Cyclophosphamide; Disease-Free Survival; Female; Hematopoietic Stem Cell Transpla | 2017 |
Augmented myeloablative conditioning with thiotepa in acute myeloid leukemia - improved outcomes with similar toxicity.
Topics: Adolescent; Adult; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplant | 2019 |
Ex vivo T cell-depleted versus unmodified allografts in patients with acute myeloid leukemia in first complete remission.
Topics: Adult; Aged; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Trans | 2013 |
Modeling zero-inflated count data when exposure varies: With an application to tumor counts.
Topics: Biometry; Follow-Up Studies; Humans; Models, Statistical; Poisson Distribution; Randomized Controlle | 2013 |
Role of topotecan, vinorelbine, thiotepa and gemcitabine chemotherapy in relapsed/refractory adult acute leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Dru | 2015 |
Mortality outcomes after busulfan-containing conditioning treatment and haemopoietic cell transplantation in patients with Gilbert's syndrome: a retrospective cohort study.
Topics: Adult; Bilirubin; Busulfan; Cohort Studies; Cyclophosphamide; Dose-Response Relationship, Drug; Fema | 2016 |
Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucle | 2010 |
Radiation-free allogeneic conditioning with fludarabine, carmustine, and thiotepa for acute lymphoblastic leukemia and other hematologic malignancies necessitating enhanced central nervous system activity.
Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal, Humanized; Carmustine; Central Nervous System; Cyc | 2012 |
Prognosis after high-dose chemotherapy followed by autologous stem-cell transplantation as first-line treatment in primary CNS lymphoma--a long-term follow-up study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Neop | 2012 |
Reduced-intensity conditioning with fludarabine and thiotepa for second allogeneic transplantation of relapsed patients with AML.
Topics: Adult; Aged; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Mal | 2013 |
Possible benefits of high-dose chemotherapy and autologous stem cell transplantation for adults with recurrent medulloblastoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Combined Modality Therapy | 2002 |
Topical thiotepa treatment for recurrent corneal haze after photorefractive keratectomy.
Topics: Administration, Topical; Adult; Antineoplastic Agents, Alkylating; Astigmatism; Corneal Opacity; Hum | 2003 |
PREVENTION ON RECURRENCE OF PTERYGIUM.
Topics: Biomedical Research; Humans; Neoplasms; Preventive Medicine; Pterygium; Recurrence; Thiotepa | 1965 |
[Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neopla | 2004 |
High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Carboplatin; Disease | 2004 |
Incidence of pterygium recurrence in patients treated with thio-tepa.
Topics: Antineoplastic Agents, Alkylating; Follow-Up Studies; Humans; Incidence; Pterygium; Recurrence; Thio | 1966 |
Parvovirus B19 pneumonia in a child undergoing allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Antineoplastic Agents; Combined Modality Therapy; Erythema Infectiosum; Fatal Outcome; H | 2007 |
The feasibility of using topotecan, vinorelbine, thiotepa and gemcitabine (TVTG) in adult patients with relapsed/refractory acute lymphoblastic leukaemia/lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Feasibility Studie | 2008 |
[Thio-tepa eyedrops against recurrent pterygium and neovascularization of the cornea].
Topics: Cornea; Humans; Neovascularization, Pathologic; Ophthalmic Solutions; Postoperative Care; Pterygium; | 1984 |
Pterygium and beta irradiation.
Topics: Dexamethasone; Humans; Postoperative Complications; Pterygium; Recurrence; Thiotepa | 1984 |
Allogeneic bone marrow transplantation for refractory and recurrent low-grade lymphoma: the case for aggressive management.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cispla | 1995 |
Factors influencing prognosis after dose-intensive therapy for recurrent or refractory Hodgkin's disease. Results of sequential trials: a case for treating patients with resistant disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carb | 1995 |
Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Drainage; | 1997 |
Recurrence of SIADH after a high-dose regimen of thiotepa, carboplatin, and etoposide phosphate.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot | 1998 |
High-dose thiotepa and etoposide-based regimens with autologous hematopoietic support for high-risk or recurrent CNS tumors in children and adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Pr | 1998 |
[Thiotepa eyedrops for prevention of pterygium recurrence: 18 years of use].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Follow-Up Studies; Humans; Middle Aged; Ophth | 1999 |
High-dose salvage chemotherapy. Germ-cell tumor treatment results in Germany.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Clinical T | 1999 |
Nonparametric analysis of recurrent events and death.
Topics: Antineoplastic Agents, Alkylating; Biometry; Cause of Death; Controlled Clinical Trials as Topic; Hu | 2000 |
New directions in diagnosis and treatment of pericardial disease. A project of the Taskforce on Pericardial Disease of the World Heart Federation.
Topics: Chronic Disease; Cisplatin; Clinical Trials as Topic; Colchicine; Heart Diseases; Heart Neoplasms; H | 2000 |
Recurrent disseminated retinoblastoma in a 7-year-old girl treated successfully by high-dose chemotherapy and CD34-selected autologous peripheral blood stem cell transplantation.
Topics: Antigens, CD34; Antineoplastic Agents; Bone Marrow Neoplasms; Bone Neoplasms; Carboplatin; Child; Cy | 2001 |
Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies.
Topics: Adult; Aged; Anemia, Refractory, with Excess of Blasts; Cyclophosphamide; Cyclosporine; Female; Graf | 2002 |
Chemotherapy in bladder carcinoma.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Recu | 1978 |
Chemotherapy of bladder tumours.
Topics: Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Papillary; Humans; Neoplasm Metastasis; Papillo | 1978 |
The management of pterygium.
Topics: Administration, Topical; Anti-Inflammatory Agents; Glucocorticoids; Humans; Postoperative Complicati | 1977 |
Malacoplakia of the urinary tract: challenges and frustations with 10 cases.
Topics: Adult; Aged; Ammonium Chloride; Anti-Bacterial Agents; Electrocoagulation; Female; Humans; Liver Dis | 1977 |
The prophylactic use of Thio-TEPA, an adjuvant in the treatment of bladder tumours.
Topics: Humans; Recurrence; Thiotepa; Urinary Bladder Neoplasms | 1977 |
The effect of intravesical thio-tepa on normal and tumor urothelium.
Topics: Carcinoma, Transitional Cell; Epithelium; Humans; Recurrence; Thiotepa; Urinary Bladder; Urinary Bla | 1978 |
[Effect of different regimens of chemotherapy and x-ray irradiation on the kinetics of experimental tumor growth].
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Dose-Response Relationship, Drug; Dose-Response Relations | 1975 |
Vesicoureteral reflux in recurrent carcinoma of the bladder--implications for treatment and prognosis.
Topics: Adult; Aged; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Prognosis; Recurrence; | 1976 |
Treatment of pterygia in Queensland.
Topics: Australia; Beta Particles; Data Collection; Humans; Postoperative Complications; Pterygium; Recurren | 1991 |
High-dose combination chemotherapy with thiotepa and autologous hematopoietic stem cell reinfusion in the treatment of patients with relapsed refractory lymphomas.
Topics: Adult; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; | 1990 |
Managing carcinoma of the bladder.
Topics: Aged; Biopsy; Cystoscopy; Electrosurgery; Female; Hematuria; Humans; Male; Palliative Care; Recurren | 1974 |
Surgery, thio-tepa, and corticosteroid in the treatment of pterygium.
Topics: Dexamethasone; Follow-Up Studies; Humans; Pigmentation Disorders; Pterygium; Recurrence; Sunlight; T | 1972 |
Clinical evaluation of patients treated for rhabdomyosarcoma.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cyclophosphamide; Evaluation Studies as Topic; Fem | 1972 |