thiotepa has been researched along with Polyneuropathy, Acquired in 1 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Women with metastatic breast cancer and at least a partial response (PR) to induction chemotherapy received three separate high-dose cycles of chemotherapy with peripheral blood progenitor support and G-CSF." | 6.70 | Phase II trial of sequential high-dose chemotherapy with paclitaxel, melphalan and cyclophosphamide, thiotepa and carboplatin with peripheral blood progenitor support in women with responding metastatic breast cancer. ( Antman, K; Balmaceda, C; Donovan, D; Frederick, D; Haythe, J; Hesdorffer, CS; Kaufman, E; Nichols, G; Papadopoulos, K; Savage, D; Sharpe, E; Tiersten, A; Troxel, A; Vahdat, LT, 2002) |
| "Women with metastatic breast cancer and at least a partial response (PR) to induction chemotherapy received three separate high-dose cycles of chemotherapy with peripheral blood progenitor support and G-CSF." | 2.70 | Phase II trial of sequential high-dose chemotherapy with paclitaxel, melphalan and cyclophosphamide, thiotepa and carboplatin with peripheral blood progenitor support in women with responding metastatic breast cancer. ( Antman, K; Balmaceda, C; Donovan, D; Frederick, D; Haythe, J; Hesdorffer, CS; Kaufman, E; Nichols, G; Papadopoulos, K; Savage, D; Sharpe, E; Tiersten, A; Troxel, A; Vahdat, LT, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vahdat, LT | 1 |
| Balmaceda, C | 1 |
| Papadopoulos, K | 1 |
| Frederick, D | 1 |
| Donovan, D | 1 |
| Sharpe, E | 1 |
| Kaufman, E | 1 |
| Savage, D | 1 |
| Tiersten, A | 1 |
| Nichols, G | 1 |
| Haythe, J | 1 |
| Troxel, A | 1 |
| Antman, K | 1 |
| Hesdorffer, CS | 1 |
1 trial available for thiotepa and Polyneuropathy, Acquired
| Article | Year |
|---|---|
Phase II trial of sequential high-dose chemotherapy with paclitaxel, melphalan and cyclophosphamide, thiotepa and carboplatin with peripheral blood progenitor support in women with responding metastatic breast cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cy | 2002 |