Compounds > thiotepa
Page last updated: 2024-11-05

thiotepa and Pleural Effusion

thiotepa has been researched along with Pleural Effusion in 16 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"Malignant pleural effusion is a common complication of malignant disease requiring drainage and palliative sclerosing therapy in the vast majority of cases."1.28[Pleurodesis with tetracycline hydrochloride]. ( Frank, W; Grosser, H; Loddenkemper, R; Mai, J, 1989)
"A pleural effusion is a frequent complication of malignant disease."1.26Management of malignant pleural effusion. ( Bennett, JM; Greenwald, DW; Phillips, C, 1978)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199016 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BRU, A1
ZELENIK, JS1
HALPERN, AJ1
WILLIAMS, DW1
GRENVILLE-MATHERS, R1
TRENCHARD, HJ1
GOLDMAN, BS1
PEARSON, FG1
Berrill, WT1
Lee, CM1
Huang, WC1
Greenwald, DW1
Phillips, C1
Bennett, JM1
Mejer, J1
Mortensen, KM1
Hansen, HH1
Frank, W1
Grosser, H1
Mai, J1
Loddenkemper, R1
Schwandt, P1
Ehrhart, H1
MacGregor, AB1
Macleod, DA1
Thomson, JW1
Andersen, AP1
Brincker, H1
Silverberg, I1
Fracchia, AA1
Knapper, WH1
Carey, JT1
Farrow, JH1
Affandi, MZ1
Sirsat, SM1
Donegan, WL1

Trials

1 trial available for thiotepa and Pleural Effusion

ArticleYear
Mepacrine hydrochloride in the treatment of malignant pleural effusion. A controlled randomized trial.
    Scandinavian journal of respiratory diseases, 1977, Volume: 58, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neoplasms; Pleura; Pleural

1977

Other Studies

15 other studies available for thiotepa and Pleural Effusion

ArticleYear
[APROPOS OF THE RESPECTIVE INDICATIONS OF RADIOACTIVE COLLOIDS AND ANTIMITOTICS IN THE TREATMENT OF CARCINOSIS OF THE SEROUS MEMBRANES].
    Minerva nucleare, 1963, Volume: 7

    Topics: Antimitotic Agents; Ascites; Colloids; Exudates and Transudates; Humans; Neoplasms; Phosphorus Isoto

1963
TREATMENT OF NEOPLASTIC EFFUSIONS WITH CHLORAMBUCIL.
    Obstetrics and gynecology, 1964, Volume: 23

    Topics: Ascites; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplasms; Pharmacology; Pleural Effusion;

1964
CYTOTOXIC DRUGS IN BRONCHIAL CARCINOMA.
    Lancet (London, England), 1964, Dec-05, Volume: 2, Issue:7371

    Topics: Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Bronchogenic; Cyclophospha

1964
MALIGNANT PERICARDIAL EFFUSION. REVIEW OF HOSPITAL EXPERIENCE AND REPORT OF A CASE SUCCESSFULLY TREATED BY TALC POUDRAGE.
    Canadian journal of surgery. Journal canadien de chirurgie, 1965, Volume: 8

    Topics: Breast Neoplasms; Cardiac Surgical Procedures; Cardiac Tamponade; Drug Therapy; Exudates and Transud

1965
Pleural aspiration and biopsy.
    British medical journal, 1980, Sep-27, Volume: 281, Issue:6244

    Topics: Biopsy; Bleomycin; Humans; Inhalation; Injections; Pleural Effusion; Thiotepa

1980
[Intrapleural thiotepa for malignant pleural effusions (author's transl)].
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1982, Volume: 81, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pl

1982
Management of malignant pleural effusion.
    Journal of surgical oncology, 1978, Volume: 10, Issue:4

    Topics: Bleomycin; Fluorouracil; Gold Radioisotopes; Humans; Mechlorethamine; Methods; Neoplasms; Phosphorus

1978
[Pleurodesis with tetracycline hydrochloride].
    Pneumologie (Stuttgart, Germany), 1989, Volume: 43, Issue:2

    Topics: Drainage; Humans; Pleural Effusion; Pleural Neoplasms; Tetracycline; Thiotepa; Thoracoscopy

1989
[Local treatment of carcinomatous effusions with triethylenethiophosphoramide (thio-tepa)].
    Munchener medizinische Wochenschrift (1950), 1966, Dec-16, Volume: 108, Issue:50

    Topics: Aged; Exudates and Transudates; Female; Humans; Male; Middle Aged; Palliative Care; Peritoneal Neopl

1966
Combined chemotherapy in the treatment of malignant effusions.
    The British journal of surgery, 1969, Volume: 56, Issue:7

    Topics: Alkylating Agents; Antineoplastic Agents; Ascites; Ascitic Fluid; Blood Cell Count; Blood Platelets;

1969
Intracavitary thiotepa in malignant pleural and peritoneal effusions.
    Acta radiologica: therapy, physics, biology, 1968, Volume: 7, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Child; Exudates and Transudates; Female; Follow-Up Studies; Gastroint

1968
Management of effusions.
    Oncology, 1970, Volume: 24, Issue:1

    Topics: Alkylating Agents; Ascites; Diuretics; Drainage; Fluorine; Gold Isotopes; Humans; Irritants; Neoplas

1970
Intrapleural chemotherapy for effusion from metastatic breast carcinoma.
    Cancer, 1970, Volume: 26, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Drainage; Female; Humans; Inhalation; Intubation; Middle A

1970
Cytological studies on exfoliated cells in serous effusions.
    Indian journal of cancer, 1970, Volume: 7, Issue:4

    Topics: Ascitic Fluid; Blood Cells; Histiocytes; Humans; Mannomustine; Neoplasm Metastasis; Neoplasms; Pleur

1970
Cancer of the breast. Endocrine ablation, hormone therapy and chemotherapy.
    Major problems in clinical surgery, 1967, Volume: 5

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Adult; Age Factors; Breast Neoplasms; Castration; Dyspnea; F

1967