Page last updated: 2024-11-05

thiotepa and Osteogenic Sarcoma

thiotepa has been researched along with Osteogenic Sarcoma in 12 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"ThioTEPA was administered intravenously every three weeks, at a dose of 65 mg/m2."2.68A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study. ( Balis, FM; Bleyer, WA; Broxson, E; Geyer, JR; Heideman, R; Krailo, MD; Poplack, D; Sato, JK, 1996)
"Melphalan was given i."2.68High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors. ( Ater, J; Chan, KW; Choroszy, M; Herzog, C; Jaffe, N; Korbling, M; Petropoulos, D, 1997)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Marec-Berard, P1
Dalban, C1
Gaspar, N1
Brugieres, L1
Gentet, JC1
Lervat, C1
Corradini, N1
Castex, MP1
Schmitt, C1
Pacquement, H1
Tabone, MD1
Brahmi, M1
Metzger, S1
Blay, JY1
PĂ©rol, D1
Uemura, S1
Mori, T1
Ishiko, S1
Takafuji, S1
Nino, N1
Yamamoto, N1
Hayakawa, A1
Nishimura, N1
Hara, H1
Kawamoto, T1
Akisue, T1
Iijima, K1
YAMAGUCHI, H1
TERASHITA, N1
TABUCHI, Y1
IKEDA, E1
FUKUI, S1
BIRINGER, A1
HOLAN, J1
MEDLA, F1
Geyer, JR1
Balis, FM1
Krailo, MD1
Heideman, R1
Broxson, E1
Sato, JK1
Poplack, D1
Bleyer, WA1
Chan, KW1
Petropoulos, D1
Choroszy, M1
Herzog, C1
Jaffe, N1
Ater, J1
Korbling, M1
Livingston, RB1
Mahaley, MS1
Woodhall, B1
Grants, EA1
Utkin, VV1
Utkin, AV1
Boeckl, O1
Hell, E1
Zimmermann, G1
Kolessov, VI1
Levin, AO1
Musaev, KD1

Reviews

2 reviews available for thiotepa and Osteogenic Sarcoma

ArticleYear
Chemotherapy of solid tumors. Recent advances.
    Postgraduate medicine, 1976, Volume: 59, Issue:2

    Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinom

1976
[Regional perfusion therapy of malignant tumors of the extremities].
    Deutsche medizinische Wochenschrift (1946), 1970, Mar-27, Volume: 95, Issue:13

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regi

1970

Trials

4 trials available for thiotepa and Osteogenic Sarcoma

ArticleYear
A multicentric randomized phase II clinical trial evaluating high-dose thiotepa as adjuvant treatment to standard chemotherapy in patients with resectable relapsed osteosarcoma.
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 125

    Topics: Adolescent; Adult; Child; Female; Humans; Male; Osteosarcoma; Thiotepa; Young Adult

2020
Retrospective analysis of high-dose chemotherapy followed by autologous stem cell transplantation for high-risk pediatric osteosarcoma.
    Pediatric hematology and oncology, 2020, Volume: 37, Issue:4

    Topics: Adolescent; Bone Neoplasms; Busulfan; Child; Female; Hematopoietic Stem Cell Transplantation; Humans

2020
A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.
    Investigational new drugs, 1996, Volume: 13, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Humans; Neoplasms; Neuroectode

1996
High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors.
    Bone marrow transplantation, 1997, Volume: 20, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool;

1997

Other Studies

6 other studies available for thiotepa and Osteogenic Sarcoma

ArticleYear
[Triethylenethiophosphoramide in the treatment of the osteosarcoma and lymphomatosis].
    Gan, 1956, Volume: 47, Issue:3-4

    Topics: Antineoplastic Agents; Bone Neoplasms; Humans; Lymphoma; Neoplasms; Osteosarcoma; Thiotepa

1956
OUR EXPERIENCES WITH CYTOSTATIC PERFUSIONS OF THE EXTREMITIES IN THE TREATMENT OF MALIGNANT TUMORS.
    Neoplasma, 1964, Volume: 11

    Topics: Animals; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dogs; Drug Ther

1964
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
    Annals of surgery, 1967, Volume: 166, Issue:2

    Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci

1967
[On the treatment of malignant tumors of the extremities].
    Voprosy onkologii, 1966, Volume: 12, Issue:9

    Topics: Amputation, Surgical; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Extremitie

1966
[Combined treatment of malignant tumors of the extremities. Regional perfusion chemotherapy].
    Minerva medica, 1970, Sep-05, Volume: 61, Issue:71

    Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Melanoma; Melphalan; Neopl

1970
[The results of treatment of maxillary sarcomas].
    Voprosy onkologii, 1970, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Fibrosarcoma; Giant Cell Tumors; Hemangiosarcoma; Humans; Lymphoma,

1970