thiotepa has been researched along with Osteogenic Sarcoma in 12 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Excerpt | Relevance | Reference |
---|---|---|
"ThioTEPA was administered intravenously every three weeks, at a dose of 65 mg/m2." | 2.68 | A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study. ( Balis, FM; Bleyer, WA; Broxson, E; Geyer, JR; Heideman, R; Krailo, MD; Poplack, D; Sato, JK, 1996) |
"Melphalan was given i." | 2.68 | High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors. ( Ater, J; Chan, KW; Choroszy, M; Herzog, C; Jaffe, N; Korbling, M; Petropoulos, D, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (66.67) | 18.7374 |
1990's | 2 (16.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 2 (16.67) | 2.80 |
Authors | Studies |
---|---|
Marec-Berard, P | 1 |
Dalban, C | 1 |
Gaspar, N | 1 |
Brugieres, L | 1 |
Gentet, JC | 1 |
Lervat, C | 1 |
Corradini, N | 1 |
Castex, MP | 1 |
Schmitt, C | 1 |
Pacquement, H | 1 |
Tabone, MD | 1 |
Brahmi, M | 1 |
Metzger, S | 1 |
Blay, JY | 1 |
PĂ©rol, D | 1 |
Uemura, S | 1 |
Mori, T | 1 |
Ishiko, S | 1 |
Takafuji, S | 1 |
Nino, N | 1 |
Yamamoto, N | 1 |
Hayakawa, A | 1 |
Nishimura, N | 1 |
Hara, H | 1 |
Kawamoto, T | 1 |
Akisue, T | 1 |
Iijima, K | 1 |
YAMAGUCHI, H | 1 |
TERASHITA, N | 1 |
TABUCHI, Y | 1 |
IKEDA, E | 1 |
FUKUI, S | 1 |
BIRINGER, A | 1 |
HOLAN, J | 1 |
MEDLA, F | 1 |
Geyer, JR | 1 |
Balis, FM | 1 |
Krailo, MD | 1 |
Heideman, R | 1 |
Broxson, E | 1 |
Sato, JK | 1 |
Poplack, D | 1 |
Bleyer, WA | 1 |
Chan, KW | 1 |
Petropoulos, D | 1 |
Choroszy, M | 1 |
Herzog, C | 1 |
Jaffe, N | 1 |
Ater, J | 1 |
Korbling, M | 1 |
Livingston, RB | 1 |
Mahaley, MS | 1 |
Woodhall, B | 1 |
Grants, EA | 1 |
Utkin, VV | 1 |
Utkin, AV | 1 |
Boeckl, O | 1 |
Hell, E | 1 |
Zimmermann, G | 1 |
Kolessov, VI | 1 |
Levin, AO | 1 |
Musaev, KD | 1 |
2 reviews available for thiotepa and Osteogenic Sarcoma
Article | Year |
---|---|
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinom | 1976 |
[Regional perfusion therapy of malignant tumors of the extremities].
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regi | 1970 |
4 trials available for thiotepa and Osteogenic Sarcoma
Article | Year |
---|---|
A multicentric randomized phase II clinical trial evaluating high-dose thiotepa as adjuvant treatment to standard chemotherapy in patients with resectable relapsed osteosarcoma.
Topics: Adolescent; Adult; Child; Female; Humans; Male; Osteosarcoma; Thiotepa; Young Adult | 2020 |
Retrospective analysis of high-dose chemotherapy followed by autologous stem cell transplantation for high-risk pediatric osteosarcoma.
Topics: Adolescent; Bone Neoplasms; Busulfan; Child; Female; Hematopoietic Stem Cell Transplantation; Humans | 2020 |
A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Humans; Neoplasms; Neuroectode | 1996 |
High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; | 1997 |
6 other studies available for thiotepa and Osteogenic Sarcoma
Article | Year |
---|---|
[Triethylenethiophosphoramide in the treatment of the osteosarcoma and lymphomatosis].
Topics: Antineoplastic Agents; Bone Neoplasms; Humans; Lymphoma; Neoplasms; Osteosarcoma; Thiotepa | 1956 |
OUR EXPERIENCES WITH CYTOSTATIC PERFUSIONS OF THE EXTREMITIES IN THE TREATMENT OF MALIGNANT TUMORS.
Topics: Animals; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dogs; Drug Ther | 1964 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci | 1967 |
[On the treatment of malignant tumors of the extremities].
Topics: Amputation, Surgical; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Extremitie | 1966 |
[Combined treatment of malignant tumors of the extremities. Regional perfusion chemotherapy].
Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Melanoma; Melphalan; Neopl | 1970 |
[The results of treatment of maxillary sarcomas].
Topics: Adolescent; Adult; Aged; Child; Fibrosarcoma; Giant Cell Tumors; Hemangiosarcoma; Humans; Lymphoma, | 1970 |