thiotepa has been researched along with Osteogenic Sarcoma in 12 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "ThioTEPA was administered intravenously every three weeks, at a dose of 65 mg/m2." | 2.68 | A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study. ( Balis, FM; Bleyer, WA; Broxson, E; Geyer, JR; Heideman, R; Krailo, MD; Poplack, D; Sato, JK, 1996) |
| "Melphalan was given i." | 2.68 | High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors. ( Ater, J; Chan, KW; Choroszy, M; Herzog, C; Jaffe, N; Korbling, M; Petropoulos, D, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Marec-Berard, P | 1 |
| Dalban, C | 1 |
| Gaspar, N | 1 |
| Brugieres, L | 1 |
| Gentet, JC | 1 |
| Lervat, C | 1 |
| Corradini, N | 1 |
| Castex, MP | 1 |
| Schmitt, C | 1 |
| Pacquement, H | 1 |
| Tabone, MD | 1 |
| Brahmi, M | 1 |
| Metzger, S | 1 |
| Blay, JY | 1 |
| Pérol, D | 1 |
| Uemura, S | 1 |
| Mori, T | 1 |
| Ishiko, S | 1 |
| Takafuji, S | 1 |
| Nino, N | 1 |
| Yamamoto, N | 1 |
| Hayakawa, A | 1 |
| Nishimura, N | 1 |
| Hara, H | 1 |
| Kawamoto, T | 1 |
| Akisue, T | 1 |
| Iijima, K | 1 |
| YAMAGUCHI, H | 1 |
| TERASHITA, N | 1 |
| TABUCHI, Y | 1 |
| IKEDA, E | 1 |
| FUKUI, S | 1 |
| BIRINGER, A | 1 |
| HOLAN, J | 1 |
| MEDLA, F | 1 |
| Geyer, JR | 1 |
| Balis, FM | 1 |
| Krailo, MD | 1 |
| Heideman, R | 1 |
| Broxson, E | 1 |
| Sato, JK | 1 |
| Poplack, D | 1 |
| Bleyer, WA | 1 |
| Chan, KW | 1 |
| Petropoulos, D | 1 |
| Choroszy, M | 1 |
| Herzog, C | 1 |
| Jaffe, N | 1 |
| Ater, J | 1 |
| Korbling, M | 1 |
| Livingston, RB | 1 |
| Mahaley, MS | 1 |
| Woodhall, B | 1 |
| Grants, EA | 1 |
| Utkin, VV | 1 |
| Utkin, AV | 1 |
| Boeckl, O | 1 |
| Hell, E | 1 |
| Zimmermann, G | 1 |
| Kolessov, VI | 1 |
| Levin, AO | 1 |
| Musaev, KD | 1 |
2 reviews available for thiotepa and Osteogenic Sarcoma
| Article | Year |
|---|---|
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinom | 1976 |
[Regional perfusion therapy of malignant tumors of the extremities].
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regi | 1970 |
4 trials available for thiotepa and Osteogenic Sarcoma
| Article | Year |
|---|---|
A multicentric randomized phase II clinical trial evaluating high-dose thiotepa as adjuvant treatment to standard chemotherapy in patients with resectable relapsed osteosarcoma.
Topics: Adolescent; Adult; Child; Female; Humans; Male; Osteosarcoma; Thiotepa; Young Adult | 2020 |
Retrospective analysis of high-dose chemotherapy followed by autologous stem cell transplantation for high-risk pediatric osteosarcoma.
Topics: Adolescent; Bone Neoplasms; Busulfan; Child; Female; Hematopoietic Stem Cell Transplantation; Humans | 2020 |
A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Humans; Neoplasms; Neuroectode | 1996 |
High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; | 1997 |
6 other studies available for thiotepa and Osteogenic Sarcoma
| Article | Year |
|---|---|
[Triethylenethiophosphoramide in the treatment of the osteosarcoma and lymphomatosis].
Topics: Antineoplastic Agents; Bone Neoplasms; Humans; Lymphoma; Neoplasms; Osteosarcoma; Thiotepa | 1956 |
OUR EXPERIENCES WITH CYTOSTATIC PERFUSIONS OF THE EXTREMITIES IN THE TREATMENT OF MALIGNANT TUMORS.
Topics: Animals; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dogs; Drug Ther | 1964 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci | 1967 |
[On the treatment of malignant tumors of the extremities].
Topics: Amputation, Surgical; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Extremitie | 1966 |
[Combined treatment of malignant tumors of the extremities. Regional perfusion chemotherapy].
Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Melanoma; Melphalan; Neopl | 1970 |
[The results of treatment of maxillary sarcomas].
Topics: Adolescent; Adult; Aged; Child; Fibrosarcoma; Giant Cell Tumors; Hemangiosarcoma; Humans; Lymphoma, | 1970 |