thiotepa has been researched along with Obesity in 3 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "An obese 53-year-old woman (height 167 cm, weight 130 kg) with metastatic breast cancer received high-dose chemotherapy comprising cyclophosphamide, thiotepa and carboplatin (CTC)." | 3.71 | Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin. ( Beijnen, JH; De Jonge, ME; Mathôt, RA; Rodenhuis, S; Van Dam, SM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simon, N | 1 |
| Coiteux, V | 1 |
| Bruno, B | 1 |
| Taque, S | 1 |
| Charbonnier, A | 1 |
| Souchet, L | 1 |
| Vincent, L | 1 |
| Yakoub-Agha, I | 1 |
| Chalandon, Y | 1 |
| De Jonge, ME | 1 |
| Mathôt, RA | 1 |
| Van Dam, SM | 1 |
| Beijnen, JH | 1 |
| Rodenhuis, S | 1 |
| Nishimura, H | 1 |
| Terada, M | 1 |
| Yasuda, M | 1 |
1 review available for thiotepa and Obesity
| Article | Year |
|---|---|
[Dose adaptation of the drugs used for hematopoietic stem-cell transplantation in patients with comorbidity: Obesity, chronic renal disease or hepatopathy: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-T
Topics: Adult; Age Factors; Busulfan; Child; Comorbidity; Cyclophosphamide; Etoposide; France; Hematopoietic | 2017 |
2 other studies available for thiotepa and Obesity
| Article | Year |
|---|---|
Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Carboplatin; Cyc | 2002 |
Mitigated teratogenicity of thio-TEPA in goldthioglucose obese mice.
Topics: Abnormalities, Drug-Induced; Animals; Clubfoot; Female; Fingers; Glucose; Gold; Mice; Obesity; Pregn | 1967 |