Page last updated: 2024-11-05

thiotepa and Neoplasm Seeding

thiotepa has been researched along with Neoplasm Seeding in 7 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Neoplasm Seeding: The local implantation of tumor cells by contamination of instruments and surgical equipment during and after surgical resection, resulting in local growth of the cells and tumor formation.

Research Excerpts

ExcerptRelevanceReference
"7."2.38Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma. ( Jordan, AM; Murphy, WM; Soloway, MS, 1989)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mack, F1
Baumert, BG1
Schäfer, N1
Hattingen, E1
Scheffler, B1
Herrlinger, U1
Glas, M1
Kaneko, A1
Suzuki, S1
Soloway, MS2
Papaioannou, AN1
Boyd, PJ1
Burnand, KG1
Jordan, AM1
Murphy, WM1
Rismukhamedova, RS1
Musapirova, NA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Involved-field Radiotherapy Combined With Concurrent Intrathecal-MTX Versus Intrathecal-Ara-C for Leptomeningeal Metastases From Solid Tumor: A Randomized Phase II Clinical Trial[NCT03082144]Phase 253 participants (Actual)Interventional2017-02-01Completed
An Open, Single-centre Non-randomized Phase II Clinical Trial on Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage[NCT01393769]Phase 25 participants (Actual)Interventional2009-11-30Terminated (stopped due to Only 5 subjects could be enrolled. Sample of 25 pat. not be achieved (rare disease).)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for thiotepa and Neoplasm Seeding

ArticleYear
Therapy of leptomeningeal metastasis in solid tumors.
    Cancer treatment reviews, 2016, Volume: 43

    Topics: Antineoplastic Agents; Cytarabine; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Ne

2016
Eye-preservation treatment of retinoblastoma with vitreous seeding.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Brachytherapy; Combined Modality Therapy; Humans; Inject

2003
Rationale for intensive intravesical chemotherapy for superficial bladder cancer.
    The Journal of urology, 1980, Volume: 123, Issue:4

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Doxorubicin; Humans; Mito

1980
Preoperative chemotherapy for operable solid tumours.
    European journal of cancer, 1981, Volume: 17, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents; Child; Cyclophosphamide; Female; Humans; Immunosuppression Th

1981
Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma.
    Progress in clinical and biological research, 1989, Volume: 310

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma in Situ; Carcinoma, Tran

1989

Other Studies

2 other studies available for thiotepa and Neoplasm Seeding

ArticleYear
Proceedings: Adjuvant intravesical thiotepa and bladder tumour recurrence.
    The British journal of surgery, 1975, Volume: 62, Issue:2

    Topics: Humans; Neoplasm Recurrence, Local; Neoplasm Seeding; Thiotepa; Urinary Bladder Neoplasms

1975
[Prevention of dissemination of cervix neoplasms during surgery].
    Voprosy onkologii, 1970, Volume: 16, Issue:9

    Topics: Endometriosis; Ethanol; Female; Humans; Leiomyoma; Neoplasm Metastasis; Neoplasm Seeding; Ovarian Ne

1970