thiotepa has been researched along with Neoplasm Seeding in 7 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Neoplasm Seeding: The local implantation of tumor cells by contamination of instruments and surgical equipment during and after surgical resection, resulting in local growth of the cells and tumor formation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "7." | 2.38 | Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma. ( Jordan, AM; Murphy, WM; Soloway, MS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mack, F | 1 |
| Baumert, BG | 1 |
| Schäfer, N | 1 |
| Hattingen, E | 1 |
| Scheffler, B | 1 |
| Herrlinger, U | 1 |
| Glas, M | 1 |
| Kaneko, A | 1 |
| Suzuki, S | 1 |
| Soloway, MS | 2 |
| Papaioannou, AN | 1 |
| Boyd, PJ | 1 |
| Burnand, KG | 1 |
| Jordan, AM | 1 |
| Murphy, WM | 1 |
| Rismukhamedova, RS | 1 |
| Musapirova, NA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Involved-field Radiotherapy Combined With Concurrent Intrathecal-MTX Versus Intrathecal-Ara-C for Leptomeningeal Metastases From Solid Tumor: A Randomized Phase II Clinical Trial[NCT03082144] | Phase 2 | 53 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| An Open, Single-centre Non-randomized Phase II Clinical Trial on Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage[NCT01393769] | Phase 2 | 5 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to Only 5 subjects could be enrolled. Sample of 25 pat. not be achieved (rare disease).) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for thiotepa and Neoplasm Seeding
| Article | Year |
|---|---|
Therapy of leptomeningeal metastasis in solid tumors.
Topics: Antineoplastic Agents; Cytarabine; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Ne | 2016 |
Eye-preservation treatment of retinoblastoma with vitreous seeding.
Topics: Animals; Antineoplastic Agents, Alkylating; Brachytherapy; Combined Modality Therapy; Humans; Inject | 2003 |
Rationale for intensive intravesical chemotherapy for superficial bladder cancer.
Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Doxorubicin; Humans; Mito | 1980 |
Preoperative chemotherapy for operable solid tumours.
Topics: Adult; Animals; Antineoplastic Agents; Child; Cyclophosphamide; Female; Humans; Immunosuppression Th | 1981 |
Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma.
Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma in Situ; Carcinoma, Tran | 1989 |
2 other studies available for thiotepa and Neoplasm Seeding
| Article | Year |
|---|---|
Proceedings: Adjuvant intravesical thiotepa and bladder tumour recurrence.
Topics: Humans; Neoplasm Recurrence, Local; Neoplasm Seeding; Thiotepa; Urinary Bladder Neoplasms | 1975 |
[Prevention of dissemination of cervix neoplasms during surgery].
Topics: Endometriosis; Ethanol; Female; Humans; Leiomyoma; Neoplasm Metastasis; Neoplasm Seeding; Ovarian Ne | 1970 |