thiotepa has been researched along with Lymph Node Metastasis in 83 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of docetaxel plus thiotepa(TXT/TSPA) and docetaxel plus capecitabine(TXT/CAPE) in patients with metastatic breast cancer." | 9.15 | [Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer]. ( Che, L; DI, Lj; Jia, J; Jiang, Hf; Liang, X; Ren, J; Song, Gh; Wang, Xl; Yang, Hb; Yu, J; Zhang, J; Zhou, Xn; Zhu, Yl, 2011) |
| " Therefore, we developed an individualised fluorouracil, epirubicin, cyclophosphamide (FEC) regimen to improve outcomes in patients with high-risk early breast cancer." | 9.09 | Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial. Scandinavian Breast Group 9401 study. ( Anker, G; Bengtsson, NO; Bergh, J; Blomqvist, C; Erikstein, B; Holte, H; Kellokumpu-Lehtinen, P; Lidbrink, E; Lindman, H; Ljungman, P; Malmström, P; Nilsson, J; Ottosson, S; Salminen, E; Söderlund, G; Wiklund, T; Wilking, N; Wist, E, 2000) |
| "The purpose of this study was to determine the feasibility and efficacy of multiple courses of high-dose cyclophosphamide, carboplatin and thiotepa with peripheral blood progenitor cell (PBPC) transplantation in women with advanced breast cancer." | 9.09 | Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer. ( Baars, JW; Beijnen, JH; Holtkamp, MJ; Rodenhuis, S; Schornagel, JH; Schrama, JG, 2001) |
| "Thirty-eight women with responsive metastatic breast cancer received high-dose cyclophosphamide (3 to 6 g/m2 over 4 days), thiotepa (400 to 800 mg/m2), and novobiocin (0." | 9.08 | Phase I and pharmacologic study of the alkylating agent modulator novobiocin in combination with high-dose chemotherapy for the treatment of metastatic breast cancer. ( Armstrong, DK; Chen, TL; Clarke, BV; Colvin, OM; Davidson, NE; Grochow, LB; Huelskamp, AM; Kennedy, MJ; Ohly, K, 1995) |
| "The incidence of secondary myelodysplasia/acute myeloid leukemia (AML) was retrospectively assessed in an international joint study in 305 node-positive breast cancer patients, who received mitoxantrone-based high-dose chemotherapy (HDCT) followed by autologous stem cell support as adjuvant therapy." | 8.82 | Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients. ( Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR, 2003) |
| "To evaluate the efficacy and safety of docetaxel plus thiotepa(TXT/TSPA) and docetaxel plus capecitabine(TXT/CAPE) in patients with metastatic breast cancer." | 5.15 | [Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer]. ( Che, L; DI, Lj; Jia, J; Jiang, Hf; Liang, X; Ren, J; Song, Gh; Wang, Xl; Yang, Hb; Yu, J; Zhang, J; Zhou, Xn; Zhu, Yl, 2011) |
| "We randomly assigned 540 female patients with primary breast cancer and at least 10 involved ipsilateral axillary lymph nodes to receive either six cycles of adjuvant chemotherapy with cyclophosphamide, doxorubicin, and fluorouracil (CAF) or the same adjuvant chemotherapy followed by high-dose chemotherapy with cyclophosphamide and thiotepa and autologous hematopoietic stem-cell transplantation." | 5.10 | Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer. ( Fetting, J; Gradishar, WJ; Gray, R; Lazarus, HM; LeMaistre, CF; Osborne, CK; Paietta, E; Pisansky, TM; Robert, NJ; Tallman, MS; Vaughan, WP, 2003) |
| " Therefore, we developed an individualised fluorouracil, epirubicin, cyclophosphamide (FEC) regimen to improve outcomes in patients with high-risk early breast cancer." | 5.09 | Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial. Scandinavian Breast Group 9401 study. ( Anker, G; Bengtsson, NO; Bergh, J; Blomqvist, C; Erikstein, B; Holte, H; Kellokumpu-Lehtinen, P; Lidbrink, E; Lindman, H; Ljungman, P; Malmström, P; Nilsson, J; Ottosson, S; Salminen, E; Söderlund, G; Wiklund, T; Wilking, N; Wist, E, 2000) |
| " As data including pre-and post-treatment samples are lacking, we studied leukocyte telomere length and telomerase activity before and after treatment in breast cancer patients randomized to receive 5 adjuvant courses FEC (5-FU, epirubicin and cyclophosphamide) (n = 17), or 4 x FEC followed by high-dose cyclophosphamide, thiotepa, carboplatin and autologous PBSCT (n = 16)." | 5.09 | Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation. ( de Jong, S; de Leij, LF; de Vries, EG; Mulder, NH; Ruiters, MH; Schröder, CP; van der Graaf, WT; van der Zee, AG; Wisman, GB, 2001) |
| "The purpose of this study was to determine the feasibility and efficacy of multiple courses of high-dose cyclophosphamide, carboplatin and thiotepa with peripheral blood progenitor cell (PBPC) transplantation in women with advanced breast cancer." | 5.09 | Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer. ( Baars, JW; Beijnen, JH; Holtkamp, MJ; Rodenhuis, S; Schornagel, JH; Schrama, JG, 2001) |
| "Thirty-eight women with responsive metastatic breast cancer received high-dose cyclophosphamide (3 to 6 g/m2 over 4 days), thiotepa (400 to 800 mg/m2), and novobiocin (0." | 5.08 | Phase I and pharmacologic study of the alkylating agent modulator novobiocin in combination with high-dose chemotherapy for the treatment of metastatic breast cancer. ( Armstrong, DK; Chen, TL; Clarke, BV; Colvin, OM; Davidson, NE; Grochow, LB; Huelskamp, AM; Kennedy, MJ; Ohly, K, 1995) |
| "The incidence of secondary myelodysplasia/acute myeloid leukemia (AML) was retrospectively assessed in an international joint study in 305 node-positive breast cancer patients, who received mitoxantrone-based high-dose chemotherapy (HDCT) followed by autologous stem cell support as adjuvant therapy." | 4.82 | Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients. ( Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR, 2003) |
| "CTCb (cyclophosphamide 6 g/m2, thiotepa 500 mg/m2 and carboplatin 800 mg/m2) was administered with autologous peripheral hematopoietic progenitor cells transplantation (TACPHP) and granulocytic colony stimulating factor (G-CSF) 5 micrograms/kg/day to 27 patients with breast cancer: 9 in stage IV in complete remission, 12 in stage II with > or = 10 affected lymph nodes and 6 in stage III." | 3.69 | [High-dosage chemotherapy and the autologous transplantation of peripheral hematopoietic progenitor cells in breast cancer: the initial results, analysis of toxicity and the necessary support means]. ( Alonso, MC; Amill, B; Bellet, M; Maroto, P; Mendoza, L; Mesía, R; Ojeda, B; Sola Rocabert, C; Tabernero, JM; Verger, G, 1995) |
| " The tumours with a TOP2A amplification contributed hardly to this difference, suggesting that TOP2A amplification is not the cause of the steep dose-response curve for anthracyclines in breast cancer." | 2.72 | Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy. ( Bontenbal, M; de Vries, EG; Hannemann, J; Hupperets, P; Kristel, P; Nooij, MA; Rodenhuis, S; Smit, WM; van de Vijver, MJ; van der Wall, E; van Hoesel, QG; van Tinteren, H; Voest, EE, 2006) |
| "Because distant visceral metastases still remain a major site of failure after this HDC regimen, a more effective systemic therapy is needed." | 2.68 | Patterns of failure following bone marrow transplantation for metastatic breast cancer: the role of consolidative local therapy. ( Ghalie, R; Hartsell, WF; Kaizer, H; Shah, AB, 1995) |
| "Radiation pneumonitis was observed in 5 patients (7%), 4 of whom had undergone high-dose chemotherapy (P = 0." | 2.68 | The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis. ( Baars, JW; Beijnen, JH; Borger, JH; Richel, DJ; Rodenhuis, S; Rutgers, EJ; Schaake-Koning, CC; Schornagel, JH; van der Wall, E; van Zandwijk, N, 1996) |
| "Patients with metastatic breast cancer (MBC) (median follow-up, 1." | 2.41 | High-dose chemotherapy and hematopoietic stem cell rescue for breast cancer: experience in California. ( Blume, KG; Cecchi, GR; Damon, LE; Glaspy, J; Gold, E; Hu, WW; Irwin, D; Linker, CA; Mason, JR; Miller, W; Stockerl-Goldstein, KE; Territo, I; Wolf, JL, 2000) |
| "Stage II patients with breast carcinoma who had undergone lumpectomy." | 1.28 | Adjuvant therapy of stage II breast cancer treated with CMFVP, radiation therapy and VATH following lumpectomy. A pilot trial. ( Allen, S; Bosworth, H; Budman, D; Lehrman, D; Lichtman, SM; Schulman, P; Vinciguerra, V; Weiselberg, L; Weiss, R, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (61.45) | 18.7374 |
| 1990's | 16 (19.28) | 18.2507 |
| 2000's | 11 (13.25) | 29.6817 |
| 2010's | 4 (4.82) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Vilsmaier, T | 1 |
| Heidegger, HH | 1 |
| Schröder, L | 1 |
| Trapp, E | 1 |
| Zehni, AZ | 1 |
| Rack, B | 1 |
| Janni, W | 1 |
| Mahner, S | 1 |
| Weissenbacher, T | 1 |
| Jeschke, U | 1 |
| Mumm, JN | 1 |
| Miltiadous, C | 1 |
| Dimitriadis, GK | 1 |
| Roditis, P | 1 |
| Kosmas, C | 1 |
| Gor, PP | 1 |
| Su, HI | 1 |
| Gray, RJ | 1 |
| Gimotty, PA | 1 |
| Horn, M | 1 |
| Aplenc, R | 1 |
| Vaughan, WP | 2 |
| Tallman, MS | 2 |
| Rebbeck, TR | 1 |
| DeMichele, A | 1 |
| Cheng, JP | 1 |
| Yan, Y | 1 |
| Wang, XY | 1 |
| Lu, YL | 1 |
| Yuan, YH | 1 |
| Jia, J | 2 |
| Ren, J | 2 |
| Yu, J | 1 |
| DI, Lj | 1 |
| Song, Gh | 1 |
| Che, L | 1 |
| Jiang, Hf | 1 |
| Zhu, Yl | 1 |
| Liang, X | 1 |
| Zhang, J | 1 |
| Yang, Hb | 1 |
| Wang, Xl | 1 |
| Zhou, Xn | 1 |
| Stemmer, SM | 1 |
| Hardan, I | 1 |
| Raz, H | 1 |
| Adamou, AK | 1 |
| Inbar, M | 1 |
| Gottfried, M | 1 |
| Merrick, Y | 1 |
| Cohen, Y | 1 |
| Sulkes, A | 1 |
| Ben-Baruch, N | 1 |
| Pfeffer, RP | 1 |
| Brenner, HJ | 1 |
| Rizel, S | 1 |
| Rodenhuis, S | 6 |
| Bontenbal, M | 2 |
| Beex, LV | 1 |
| Wagstaff, J | 1 |
| Richel, DJ | 4 |
| Nooij, MA | 2 |
| Voest, EE | 2 |
| Hupperets, P | 2 |
| van Tinteren, H | 2 |
| Peterse, HL | 1 |
| TenVergert, EM | 1 |
| de Vries, EG | 3 |
| Gray, R | 2 |
| Robert, NJ | 1 |
| LeMaistre, CF | 1 |
| Osborne, CK | 1 |
| Gradishar, WJ | 1 |
| Pisansky, TM | 1 |
| Fetting, J | 1 |
| Paietta, E | 1 |
| Lazarus, HM | 1 |
| NOER, RJ | 2 |
| RODIN, AE | 1 |
| TURNER, FW | 1 |
| COUVES, CM | 1 |
| ARIEL, IM | 1 |
| RESNICK, MI | 1 |
| GALEY, D | 1 |
| SVIATUKHINA, OV | 2 |
| HARPMAN, JA | 1 |
| SEMENOV, NK | 1 |
| GOLDMAN, BS | 1 |
| PEARSON, FG | 1 |
| Kröger, N | 2 |
| Damon, L | 1 |
| Zander, AR | 2 |
| Wandt, H | 2 |
| Derigs, G | 1 |
| Ferrante, P | 1 |
| Demirer, T | 1 |
| Rosti, G | 1 |
| Hannemann, J | 1 |
| Kristel, P | 1 |
| van Hoesel, QG | 1 |
| Smit, WM | 1 |
| van der Wall, E | 4 |
| van de Vijver, MJ | 1 |
| Schmoor, C | 1 |
| Krüger, W | 1 |
| Möbus, V | 1 |
| Frickhofen, N | 1 |
| Metzner, B | 1 |
| Berdel, WE | 1 |
| Koenigsmann, M | 1 |
| Thiel, E | 1 |
| Possinger, K | 1 |
| Kreienberg, R | 1 |
| Schumacher, M | 1 |
| Jonat, W | 1 |
| Lytkin, GV | 1 |
| Gilbert, JM | 1 |
| Irzhanov, SI | 1 |
| Serov, SF | 1 |
| Pankov, AK | 1 |
| Sidorenko, IuS | 1 |
| Il'inskaia, EG | 2 |
| Ogorodnikova, LS | 1 |
| Zubkova, TV | 1 |
| Holland, JF | 1 |
| Sola Rocabert, C | 1 |
| Mesía, R | 1 |
| Mendoza, L | 1 |
| Tabernero, JM | 1 |
| Amill, B | 1 |
| Maroto, P | 1 |
| Bellet, M | 1 |
| Ojeda, B | 1 |
| Alonso, MC | 1 |
| Verger, G | 1 |
| Nooijen, WJ | 2 |
| Baars, JW | 4 |
| Holtkamp, MJ | 2 |
| Schorangel, JH | 1 |
| Rutgers, EJ | 2 |
| Slaper-Cortenbach, IC | 1 |
| van der Schoot, CE | 1 |
| Xu, T | 1 |
| Shah, AB | 1 |
| Hartsell, WF | 1 |
| Ghalie, R | 1 |
| Kaizer, H | 1 |
| Kennedy, MJ | 1 |
| Armstrong, DK | 1 |
| Huelskamp, AM | 1 |
| Ohly, K | 1 |
| Clarke, BV | 1 |
| Colvin, OM | 1 |
| Grochow, LB | 1 |
| Chen, TL | 1 |
| Davidson, NE | 1 |
| Krementz, ET | 1 |
| Carter, RD | 1 |
| Sutherland, CM | 1 |
| Muchmore, JH | 1 |
| Ryan, RF | 1 |
| Creech, O | 1 |
| Tormey, DC | 2 |
| Falkson, HC | 1 |
| Gilchrist, K | 1 |
| Abeloff, MD | 1 |
| Falkson, G | 1 |
| Holland, HK | 1 |
| Dix, SP | 1 |
| Geller, RB | 1 |
| Devine, SM | 1 |
| Heffner, LT | 1 |
| Connaghan, DG | 1 |
| Hillyer, CD | 1 |
| Hughes, LL | 1 |
| Miller, RL | 1 |
| Moore, MR | 1 |
| Winton, EF | 1 |
| Wingard, JR | 1 |
| Schaake-Koning, CC | 1 |
| van Zandwijk, N | 1 |
| Schornagel, JH | 3 |
| Borger, JH | 2 |
| Beijnen, JH | 2 |
| Solano, C | 1 |
| Sola, C | 1 |
| Lluch, A | 1 |
| Hornedo, J | 1 |
| López, J | 1 |
| Cortés-Funes, H | 1 |
| García-Conde, J | 1 |
| Cao, Z | 1 |
| Zhang, D | 1 |
| Peng, Z | 1 |
| Koning, CC | 1 |
| Peterse, JL | 1 |
| Bakx, R | 1 |
| Dalesio, O | 1 |
| Rutgers, E | 1 |
| Nekhme, A | 1 |
| Palangié, T | 2 |
| Pierga, JY | 2 |
| Pouillart, P | 2 |
| Bergh, J | 1 |
| Wiklund, T | 1 |
| Erikstein, B | 1 |
| Lidbrink, E | 1 |
| Lindman, H | 1 |
| Malmström, P | 1 |
| Kellokumpu-Lehtinen, P | 1 |
| Bengtsson, NO | 1 |
| Söderlund, G | 1 |
| Anker, G | 1 |
| Wist, E | 1 |
| Ottosson, S | 1 |
| Salminen, E | 1 |
| Ljungman, P | 1 |
| Holte, H | 1 |
| Nilsson, J | 1 |
| Blomqvist, C | 1 |
| Wilking, N | 1 |
| Damon, LE | 1 |
| Hu, WW | 1 |
| Stockerl-Goldstein, KE | 1 |
| Blume, KG | 1 |
| Wolf, JL | 1 |
| Gold, E | 1 |
| Cecchi, GR | 1 |
| Irwin, D | 1 |
| Glaspy, J | 1 |
| Territo, I | 1 |
| Miller, W | 1 |
| Mason, JR | 1 |
| Linker, CA | 1 |
| Mouret, E | 1 |
| Diéras, V | 1 |
| Laurence, V | 1 |
| Beuzeboc, P | 1 |
| Dorval, T | 1 |
| Jouve, M | 1 |
| Vincent-Salomon, A | 1 |
| Scholl, S | 1 |
| Extra, JM | 1 |
| Asselain, B | 1 |
| Schröder, CP | 1 |
| Wisman, GB | 1 |
| de Jong, S | 1 |
| van der Graaf, WT | 1 |
| Ruiters, MH | 1 |
| Mulder, NH | 1 |
| de Leij, LF | 1 |
| van der Zee, AG | 1 |
| Schrama, JG | 1 |
| Milton, GW | 1 |
| McCarthy, WH | 1 |
| Frid, IA | 1 |
| Bavli, IaL | 3 |
| Fisher, B | 7 |
| Kavetskiĭ, RE | 1 |
| Balitskiĭ, KP | 1 |
| Veksler, IG | 1 |
| Vetrova, EP | 1 |
| Vorontsova, AL | 1 |
| Slack, N | 1 |
| Katrych, D | 1 |
| Wolmark, N | 1 |
| Cox, KR | 1 |
| Semiglazov, VF | 2 |
| Topuzov, EE | 1 |
| Ivanova, OA | 1 |
| Seleznev, IK | 1 |
| Golubeva, OM | 1 |
| Orlov, AA | 1 |
| Chepik, OF | 1 |
| Lichtman, SM | 1 |
| Budman, D | 1 |
| Bosworth, H | 1 |
| Allen, S | 1 |
| Schulman, P | 1 |
| Weiselberg, L | 1 |
| Weiss, R | 1 |
| Lehrman, D | 1 |
| Vinciguerra, V | 1 |
| Morozov, AI | 1 |
| Rogachikova, TA | 1 |
| Korshunov, AI | 1 |
| Moiseenko, VM | 1 |
| Rzhankov, SV | 1 |
| Migmanova, NSh | 1 |
| Kholdin, SA | 1 |
| Deemarsky, LY | 1 |
| Bavly, JL | 1 |
| Donegan, WL | 3 |
| Wise, L | 1 |
| Vikmanis, UE | 1 |
| Lun'kova, EF | 1 |
| Krasovskiĭ, IM | 1 |
| Komurdzhiev, KhA | 1 |
| Karpunichev, VS | 1 |
| Moskalik, KG | 1 |
| Kozlov, AP | 1 |
| Akimov, AA | 1 |
| Getzen, LC | 2 |
| Riffenburgh, RH | 1 |
| Atkins, H | 1 |
| Hayward, JL | 1 |
| Klugman, DJ | 1 |
| Wayte, AB | 1 |
| Swierzowa, J | 1 |
| Ansfield, FJ | 1 |
| Brenier, JL | 1 |
| Longmire, WP | 1 |
| Kuzma, JW | 1 |
| Dixon, WJ | 1 |
| Harvin, JS | 1 |
| Smith, JR | 1 |
| Ravdin, RG | 2 |
| Ausman, RK | 1 |
| Slack, NH | 3 |
| Moore, GE | 1 |
| Miuller, NR | 1 |
| Getzen, LG | 1 |
| Lobpreis, EL | 1 |
| Holloway, CK | 1 |
| Dwight, RW | 1 |
| Higgins, GA | 1 |
| Keehn, RJ | 1 |
| Long, RT | 1 |
| Evans, AM | 1 |
| Leipe, ER | 1 |
| Blumenson, LE | 1 |
| Bross, ID | 1 |
| Seidman, H | 1 |
| Cavanaugh, PJ | 1 |
| Gardner, B | 1 |
| Smirnova, IN | 1 |
| Stengrevits, AA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized Feasibility and Phase II Adjuvant Breast Cancer Study of the Netherlands Working Party for Autotransplantation in Solid Tumors.[NCT00851110] | Phase 2 | 50 participants (Anticipated) | Interventional | 2004-10-31 | Terminated | ||
| High-dose Chemotherapy With Hematopoietic Stem-cell Rescue for High-risk Breast Cancer: Long-term Follow-up of a Randomized Phase III Study[NCT03087409] | 885 participants (Actual) | Observational | 2016-07-31 | Completed | |||
| Profiling Neutrophil Counts in Patients With Cancer During Cycle One of Chemotherapy[NCT02806557] | 200 participants (Anticipated) | Observational | 2016-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for thiotepa and Lymph Node Metastasis
| Article | Year |
|---|---|
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantat | 2003 |
High-dose chemotherapy and hematopoietic stem cell rescue for breast cancer: experience in California.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Calif | 2000 |
Combined chemotherapy and surgery in breast cancer: a review.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mechloretham | 1975 |
Controversies in the management of potentially curable breast cancer.
Topics: Breast Neoplasms; Castration; Clinical Trials as Topic; England; Female; Fluorouracil; Humans; Lymph | 1974 |
[Use of optical quantum generators (lasers) in oncology].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Basal Cell; Carcinom | 1972 |
Cancer of the breast. Statistical and epidemiological data.
Topics: Breast Neoplasms; Ethnicity; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Th | 1969 |
The surgical dilemma in the primary therapy of invasive breast cancer: a critical appraisal.
Topics: Breast Neoplasms; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methods; Pr | 1970 |
30 trials available for thiotepa and Lymph Node Metastasis
| Article | Year |
|---|---|
Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemothe | 2010 |
[Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Capec | 2011 |
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 2003 |
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 2003 |
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 2003 |
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 2003 |
Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyc | 2003 |
Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy.
Topics: Adult; Anthracyclines; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarker | 2006 |
Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyc | 2008 |
Adjuvant chemotherapy of large bowel cancer.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Floxu | 1982 |
Adjuvant chemotherapy for breast cancer.
Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Do | 1981 |
High-dose carboplatin, thiotepa and cyclophosphamide (CTC) with peripheral blood stem cell support in the adjuvant therapy of high-risk breast cancer: a practical approach.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms | 1995 |
[Lymphatic interventional radiology in the treatment of lymphatic neoplasmas].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Lymphatic M | 1995 |
Patterns of failure following bone marrow transplantation for metastatic breast cancer: the role of consolidative local therapy.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantati | 1995 |
Phase I and pharmacologic study of the alkylating agent modulator novobiocin in combination with high-dose chemotherapy for the treatment of metastatic breast cancer.
Topics: Adult; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophos | 1995 |
Maintenance tamoxifen after induction postoperative chemotherapy in node-positive breast cancer patients: the Eastern Cooperative Oncology Group Trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosp | 1993 |
The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin | 1996 |
Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 1998 |
Dose-intense salvage therapy after neoadjuvant chemotherapy: feasibility and preliminary results.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemotherapy, | 1999 |
Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial. Scandinavian Breast Group 9401 study.
Topics: Acute Disease; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2000 |
Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial. Scandinavian Breast Group 9401 study.
Topics: Acute Disease; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2000 |
Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial. Scandinavian Breast Group 9401 study.
Topics: Acute Disease; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2000 |
Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial. Scandinavian Breast Group 9401 study.
Topics: Acute Disease; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2000 |
Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvan | 2001 |
Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Colony-Forming | 2001 |
Ten year follow-up results of patients with carcinoma of the breast in a co-operative clinical trial evaluating surgical adjuvant chemotherapy.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Female; Follow-Up Studies; Human | 1975 |
[Neoadjuvant chemotherapy in combined treatment of breast cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyc | 1992 |
Extended surgical adjuvant thiotepa for mammary carcinoma.
Topics: Adenocarcinoma; Blood Cell Count; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Femal | 1974 |
Controversies in the management of potentially curable breast cancer.
Topics: Breast Neoplasms; Castration; Clinical Trials as Topic; England; Female; Fluorouracil; Humans; Lymph | 1974 |
Treatment of early breast cancer: a report after ten years of a clinical trial.
Topics: Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Lymphatic | 1972 |
Chemotherapy in primary therapy of cancer of the breast.
Topics: Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mast | 1967 |
The use of triethylenethiophosphoramide as an adjuvant to the surgical treatment of gastric carcinoma.
Topics: Age Factors; Aged; Clinical Trials as Topic; Female; Gastrectomy; Humans; Lymphatic Metastasis; Male | 1968 |
Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation.
Topics: Adult; Aged; Axilla; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouraci | 1968 |
Factors influencing survival after resection in cancer of the colon and rectum.
Topics: Adult; Age Factors; Aged; Colonic Neoplasms; Humans; Lymphatic Metastasis; Middle Aged; Prognosis; R | 1969 |
Extended surgical adjuvant chemotherapy for breast carcinoma.
Topics: Adenocarcinoma; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Lymphatic Metastasis; Ma | 1969 |
Postoperative radiotherapy in the treatment of breast cancer: results of the NSABP clinical trial.
Topics: Adult; Age Factors; Breast Neoplasms; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Maste | 1970 |
47 other studies available for thiotepa and Lymph Node Metastasis
| Article | Year |
|---|---|
Interleukin 15 and Eotaxin correlate with the outcome of breast cancer patients vice versa independent of CTC status.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Ca | 2021 |
Plerixafor mobilization of peripheral blood hematopoietic progenitors to support further high-dose chemotherapy cycles in a patient with germ-cell tumor relapsing after previous tandem high-dose chemotherapy and hematopoietic cell transplantation: report
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Carboplatin; Cyclams; Etoposide | 2017 |
MUC1-positive circulating tumor cells and MUC1 protein predict chemotherapeutic efficacy in the treatment of metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cell | 2011 |
Adjuvant treatment of high-risk stage II breast cancer with doxorubicin followed by high-dose chemotherapy and autologous stem-cell transplantation: a single-institution experience with 132 consecutive patients.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin | 2003 |
ADJUVANT CHEMOTHERAPY. THIO-TEPA WITH RADICAL MASTECTOMY IN THE TREATMENT OF BREAST CANCER.
Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Humans; Lymphatic Metastasis; Maste | 1963 |
INFLUENCE OF ISOLATION PERFUSION WITH AN ALKYLATING AGENT ON THE HISTOPATHOLOGY AND METASTATIC PROPENSITY OF WALKER-256 CARCINOMA.
Topics: Alkylating Agents; Animals; Carcinoma 256, Walker; Chemotherapy, Cancer, Regional Perfusion; Leaders | 1963 |
THE INTRALYMPHATIC ADMINISTRATION OF RADIOACTIVE ISOTOPES AND CANCER CHEMOTHERAPEUTIC DRUGS.
Topics: Abdominal Neoplasms; Angiography; Breast Neoplasms; Geriatrics; Gold; Humans; Injections; Iodine Iso | 1964 |
HORMONE THERAPY OF PATIENTS WITH ADVANCED CANCER OF THE BREAST.
Topics: Bone Neoplasms; Breast Neoplasms; Castration; Cortisone; Estrogens; Female; Follicle Stimulating Hor | 1964 |
ON BLOCK DISSECTION OF THE NECK.
Topics: Adrenal Cortex Hormones; Carotid Arteries; Esophageal Neoplasms; Humans; Laryngeal Neoplasms; Lympha | 1964 |
[ON THE EXPEDICIENCY OF PALLIATIVE STOMACH RESECTION COMBINED WITH CHEMOTHERAPY IN CANCER].
Topics: Digestive System Surgical Procedures; Gastrectomy; Humans; Lymphatic Metastasis; Neoplasms; Palliati | 1964 |
MALIGNANT PERICARDIAL EFFUSION. REVIEW OF HOSPITAL EXPERIENCE AND REPORT OF A CASE SUCCESSFULLY TREATED BY TALC POUDRAGE.
Topics: Breast Neoplasms; Cardiac Surgical Procedures; Cardiac Tamponade; Drug Therapy; Exudates and Transud | 1965 |
[Endolymphatic use of solutions of alkylating substances in a mixture with iodolipol in malignant neoplasms].
Topics: Alkylating Agents; Cyclophosphamide; Drug Evaluation; Female; Humans; Injections, Intralymphatic; Io | 1981 |
[Mitotic activity changes in serous ovarian cystadenocarcinomas under treated with chemotherapy].
Topics: Adult; Aged; Cystadenoma; Dose-Response Relationship, Drug; Female; Humans; Lymphatic Metastasis; Mi | 1980 |
[Endolymphatic polychemotherapy of ovarian cancer].
Topics: Adolescent; Adult; Aged; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Fluor | 1981 |
[High-dosage chemotherapy and the autologous transplantation of peripheral hematopoietic progenitor cells in breast cancer: the initial results, analysis of toxicity and the necessary support means].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Combined Modal | 1995 |
Regional chemotherapy for melanoma. A 35-year experience.
Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials as Topic; Combined Modality T | 1994 |
Minimal toxicity and mortality in high-risk breast cancer patients receiving high-dose cyclophosphamide, thiotepa, and carboplatin plus autologous marrow/stem-cell transplantation and comprehensive supportive care.
Topics: Actuarial Analysis; Adult; Algorithms; Antineoplastic Agents, Alkylating; Antineoplastic Combined Ch | 1996 |
[High-dosage chemotherapy and autologous transplant of hematopoietic germ cells from peripheral blood in high-risk recurrence carcinoma of the breast (with >= or 10 involved axillary nodes at diagnosis) Preliminary results of the Solti 9301 cooperative st
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Carboplatin; Combin | 1997 |
[Chemotherapy repeated injection via pelvic retroperitoneal cannulation].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Dogs; Endometrial Ne | 1997 |
[The effect of the parameters of the therapeutic protocol on the efficacy of the adjuvant chemotherapy of breast cancer].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 1999 |
Prognostic value of persistent node involvement after neoadjuvant chemotherapy in patients with operable breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Carcinoma, Du | 2000 |
Chemotherapy for malignant melanoma: a brief review and personal experience.
Topics: Bacterial Vaccines; BCG Vaccine; Corynebacterium; Humans; Imidazoles; Lymphatic Metastasis; Melanoma | 1978 |
[Effect of anesthesia on the results of the overall treatment of breast cancer].
Topics: Anesthesia, Inhalation; Breast Neoplasms; Ether; Female; Follow-Up Studies; Halothane; Humans; Lymph | 1978 |
United States trials of adjuvant therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastect | 1977 |
[Tilorone, a synthetic immunostimulator possessing antitumor activity].
Topics: Animals; Antibody-Producing Cells; Antineoplastic Agents; Drug Evaluation, Preclinical; Fluorenes; I | 1977 |
Survival after regional perfusion for limb melanoma.
Topics: Amputation, Surgical; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Humans; Lymphat | 1975 |
Management of primary cancer of the breast. New considerations.
Topics: Breast Neoplasms; Female; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Thiotepa | 1975 |
Adjuvant therapy of stage II breast cancer treated with CMFVP, radiation therapy and VATH following lumpectomy. A pilot trial.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas | 1991 |
[Radiation therapy of malignant neoplasms of the middle ear after nonradical surgical interventions].
Topics: Adult; Combined Modality Therapy; Cyclophosphamide; Ear Neoplasms; Ear, Middle; Female; Gamma Rays; | 1985 |
[Adjuvant mono- and polychemotherapy in breast cancer (a randomized study)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cycloph | 1985 |
Adjuvant long-term chemotherapy in complex treatment of operable breast cancer.
Topics: Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Top | 1974 |
[Late results of observing patients with extensive breast cancer who have undergone chemotherapy by infusion].
Topics: Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Female; Fluorouracil; Follow-Up Studies; | 1974 |
[Intralymphatic infusion of chemotherapeutic preparations].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Female; Fibrosarcoma; Humans; Injections, Intralympha | 1968 |
[Combined chemotherapeutic and surgical treatment of patients with neglected forms of cancer of the stomach].
Topics: Adenocarcinoma, Mucinous; Adult; Gastrectomy; Gastroenterostomy; Humans; Lymphatic Metastasis; Male; | 1967 |
A statistical analysis of radical mastectomy with adjuvant therapy in the initial treatment of carcinoma of the breast.
Topics: Adult; Breast Neoplasms; Factor Analysis, Statistical; Female; Humans; Lymphatic Metastasis; Mastect | 1972 |
Clinical evaluation of patients treated for rhabdomyosarcoma.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cyclophosphamide; Evaluation Studies as Topic; Fem | 1972 |
The role of the Halsted operation in treatment of breast cancer.
Topics: Brachial Plexus; Breast Neoplasms; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastec | 1967 |
Treatment of melanoma by lymphatic perfusion and regional lymph node excision: a preliminary report.
Topics: Coloring Agents; Humans; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Perfusion; Thiotepa | 1968 |
[A study of the combined effect of antitumorous alkylating agents and vitamin B 12 on a model of a metastasizing tumor].
Topics: Animals; Lung Neoplasms; Lymphatic Metastasis; Melphalan; Neoplasm Metastasis; Neoplasm Transplantat | 1966 |
The treatment of primary breast cancer. Analysis of various therapeutic modalities.
Topics: Breast Neoplasms; Castration; Cobalt Isotopes; Female; Follow-Up Studies; Humans; Lymph Node Excisio | 1969 |
The treatment of primary breast cancer. Comments.
Topics: Adrenalectomy; Breast Neoplasms; Castration; Female; Humans; Hypophysectomy; Lymphatic Metastasis; N | 1969 |
[Results of the surgical treatment of lung cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Follow-Up Studies; | 1969 |
Therapeutic implications from a mathematical model characterizing the course of breast cancer.
Topics: Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Mastectomy; | 1969 |
Prospects for the control of metastases.
Topics: Anticoagulants; Breast Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Neoplasm Recur | 1969 |
[Results of treatment of tonsillar tumors by olivomycin].
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Chlorpromazine; Cyclophosp | 1969 |
[The efficacy of intralymphatic use of antiblastic drugs].
Topics: Animals; Antineoplastic Agents; Cats; Cyclophosphamide; Dogs; Female; Gold Colloid, Radioactive; Hod | 1969 |
Cancer of the breast. Staging and end results.
Topics: Age Factors; Axilla; Breast Neoplasms; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Ma | 1967 |