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thiotepa and Local Neoplasm Recurrence

thiotepa has been researched along with Local Neoplasm Recurrence in 256 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"To determine: (1) the maximum tolerable dose (MTD) of thiotepa (TT) that can be administered with etoposide without stem cell support; (2) whether this regimen is active against recurrent malignant gliomas."9.08Thiotepa and etoposide treatment of recurrent malignant gliomas: phase I study. ( Balmaceda, C; Fetell, MR; Hesdorffer, C, 1997)
"Twenty patients previously treated with surgery, radiation therapy and chemotherapy with a nitrosourea for malignant supratentorial gliomas received a combination of procarbazine, thiotepa and vincristine (P."9.07Treatment of recurrent malignant supratentorial gliomas with the association of procarbazine, thiotepa and vincristine: a phase II study. ( Ameri, A; Chen, QM; Delattre, JY; Poisson, M, 1993)
"To determine the role, if any, of one and five installations of intravesical thiotepa in the treatment of newly diagnosed superficial bladder cancer."9.07The effect of intravesical thiotepa on tumour recurrence after endoscopic treatment of newly diagnosed superficial bladder cancer. A further report with long-term follow-up of a Medical Research Council randomized trial. Medical Research Council Working P ( , 1994)
"This report presents the second interim analysis of data from a randomized prospective trial that compares the prophylactic effect of 15 intravesical instillations of 50 mg Doxorubicin (ADM), 50 mg of Thiotepa (TTPA), or 150 mg of Bacillus Calmette-Guérin (BCG) against recurrence and progression of superficial transitional cell bladder cancer."9.06Intravesical therapy comparing BCG, adriamycin, and thiotepa in 200 patients with superficial bladder cancer: a randomized prospective study. ( Cárcamo, P; Fiter, L; García Matres, MJ; Jimenez León, J; Martinez-Pineiro, JA; Martinez-Pineiro, L; Mosteiro, JA; Navarro, J, 1989)
"The National Bladder Cancer Group undertook a study to determine the effectiveness and toxicity of mitomycin in patients who failed on thiotepa."9.05Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group. ( Barton, B; Hazra, TA; Heney, NM; Kluskens, L; Koontz, WW; Soloway, MS; Trump, DL, 1985)
"In a prospective, randomized, stratified study with crossover design the effect of thiotepa was compared to that of mitomycin C when each was instilled intravesically immediately at the end of complete removal of superficial bladder cancer (stages Ta and Tis) and later on tumor recurrence."9.05Intravesical thiotepa and mitomycin C treatment immediately after transurethral resection and later for superficial (stages Ta and Tis) bladder cancer: a prospective, randomized, stratified study with crossover design. ( Benson, RC; Hilton, JF; Taylor, WF; Zincke, H, 1985)
"The influence of the instillation of thiotepa or doxorubicin hydrochloride into the bladder at the end of transurethral surgical treatment on the recurrence of bladder cancer was evaluated."9.05Influence of thiotepa and doxorubicin instillation at time of transurethral surgical treatment of bladder cancer on tumor recurrence: a prospective, randomized, double-blind, controlled trial. ( Leary, FJ; Myers, RP; Taylor, WF; Utz, DC; Zincke, H, 1983)
"This report describes and presents some preliminary results from a prospective clinical investigation to determine the ablative effect of thiotepa (N,N',N''-triethylene phosphoramide) on superficial low-stage bladder cancer and the effectiveness of this agent in the prevention of recurrent or new tumors."9.04The role of intravesical thiotepa in the management of superficial bladder cancer. National Bladder Cancer Collaborative Group A. ( , 1977)
"Thiotepa-based conditioning followed by HSCT may be effective in most CNS lymphoma patients, with a manageable toxicity profile."8.90Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma. ( Bredeson, C; Fergusson, D; Kokolo, MB; O'Neill, J; Stewart, D; Tay, J; Tinmouth, AT, 2014)
"Mitomycin-C (MMC) and thiotepa are intravesical agents effective in reducing the recurrence of low-grade noninvasive bladder cancer when instilled perioperatively."7.91Single-dose perioperative mitomycin-C versus thiotepa for low-grade noninvasive bladder cancer. ( Blodgett, G; Castle, EP; Chang, YH; Etzioni, DA; Faraj, K; Habermann, EB; Humphreys, MR; Rose, KM; Tyson Ii, MD, 2019)
"The aim of this study was to evaluate the efficacy and toxicity of two chemotherapy regimens based on platinum and cytarabine in association with etoposide and methylprednisolone (ESHAP) or with dexamethasone (DHAP) with or without Rituximab (± R) in patients with refractory or a relapsed Primary Central Nervous System Lymphoma (PCNSL)."7.77Platine and cytarabine-based salvage treatment for primary central nervous system lymphoma. ( Choquet, S; del Rio, MS; Fourme, E; Glaisner, S; Hoang-Xuan, K; Janvier, M; Soussain, C, 2011)
"Twenty-one percent of responding metastatic breast cancer patients remain progression-free a median 50 months following one intensification cycle of cyclophosphamide (6,000 mg/m2), thiotepa (500 mg/ m2), and carboplatin (800 mg/m2) (CTCb) with autologous bone marrow transplantation (ABMT)."7.69Double dose-intensive chemotherapy with autologous stem-cell support for metastatic breast cancer: no improvement in progression-free survival by the sequence of high-dose melphalan followed by cyclophosphamide, thiotepa, and carboplatin. ( Antman, K; Ayash, LJ; Elias, A; Frei, E; Ibrahim, J; Lynch, C; Reich, E; Richardson, P; Schnipper, L; Schwartz, G; Teicher, BA; Warren, D; Wheeler, C, 1996)
"To further improve the effect of high-dose chemotherapy in the treatment of locally advanced and metastatic breast cancer, we sought to develop a second active high-dose noncross-resistant regimen to use in tandem with our customary high-dose regimen of cyclophosphamide, etoposide, and cisplatin (CVP)."7.68A phase II study of mitoxantrone, etoposide, and thiotepa with autologous marrow support for patients with relapsed breast cancer. ( Buzdar, A; Dunphy, F; Ewer, M; Holmes, F; Hortobagyi, G; Huan, S; Spitzer, G; Theriault, R; Wallerstein, R; Yau, J, 1990)
"One hundred patients suffering from advanced breast cancers and resisting to one (15) or several (85) drugs previously administered have been treated by an association of mitomycin C, thiotepa and vindesine, given every 3 weeks."7.66[Chemotherapy associating mitomycin C, thiotepa and vindesine in advanced breast cancers. Study of 100 cases (author's transl)]. ( Brunet, R; Bui, BN; Chauvergne, J; Durand, M; Hoerni, B; Mauriac, L, 1981)
"Recurrent medulloblastoma is highly lethal in previously irradiated patients."6.75High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. ( Dunkel, IJ; Finlay, JL; Gardner, SL; Garvin, JH; Goldman, S; Shi, W, 2010)
" Haematologic toxicity is greater in the CMF group, requiring more frequent dosage reductions."6.67Randomized trial of adjuvant chemotherapy for operable breast cancer comparing i.v. CMF to an epirubicin-containing regimen [see comment]. ( Bonichon, F; Chauvergne, J; Dilhuydy, JM; Durand, M; Mauriac, L, 1992)
"Paclitaxel has minimal penetration of the blood-brain barrier and central nervous system side effects are rare."5.35Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma. ( Fangusaro, J; Finlay, J; Rook, J; Rosser, T, 2008)
"Medulloblastoma is a highly lethal disease when it recurs."5.30High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. Children's Cancer Group. ( Allen, JC; Bostrom, BC; Boyett, JM; Dunkel, IJ; Finlay, JL; Gardner, SL; Garvin, JH; Goldman, S; Li, H; Rosenblum, M; Sender, LS; Yates, A, 1998)
" These patients with progressive bladder carcinoma appeared to be unaffected by intravesical thiotepa in the dosage used."5.27Intravesical thiotepa prophylaxis of superficial bladder cancer. A follow-up study. ( Fosså, SD; Miller, A; Stenwig, AE, 1983)
"We randomly assigned 540 female patients with primary breast cancer and at least 10 involved ipsilateral axillary lymph nodes to receive either six cycles of adjuvant chemotherapy with cyclophosphamide, doxorubicin, and fluorouracil (CAF) or the same adjuvant chemotherapy followed by high-dose chemotherapy with cyclophosphamide and thiotepa and autologous hematopoietic stem-cell transplantation."5.10Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer. ( Fetting, J; Gradishar, WJ; Gray, R; Lazarus, HM; LeMaistre, CF; Osborne, CK; Paietta, E; Pisansky, TM; Robert, NJ; Tallman, MS; Vaughan, WP, 2003)
"To determine: (1) the maximum tolerable dose (MTD) of thiotepa (TT) that can be administered with etoposide without stem cell support; (2) whether this regimen is active against recurrent malignant gliomas."5.08Thiotepa and etoposide treatment of recurrent malignant gliomas: phase I study. ( Balmaceda, C; Fetell, MR; Hesdorffer, C, 1997)
" Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas using single chemotherapy agents such as cyclophosphamide, carboplatin, cisplatin, etoposide and thiotepa or combinations of chemotherapy agents have produced low response rates in the range of 15-20%."5.08Contemporary chemotherapy issues for children with brainstem gliomas. ( Allen, JC; Siffert, J, 1996)
"ThioTEPA is given intravesically in a variety of schedules to treat superficial bladder cancer."5.08ThioTEPA pharmacokinetics during intravesical chemotherapy: the influence of dose and volume of instillate on systemic uptake and dose rate to the tumour. ( Bibby, MC; Harland, S; Loadman, PM; Masters, JR; McDermott, BJ, 1996)
"By conventional Phase II criteria, thiotepa appears to have activity in medulloblastoma."5.07A phase II evaluation of thiotepa in pediatric central nervous system malignancies. ( Allen, JC; Balis, FM; Gillespie, A; Heideman, RL; Horowitz, ME; Kovnar, EH; Lange, B; Packer, RJ; Reaman, GH; Steinberg, SM, 1993)
"To determine the role, if any, of one and five installations of intravesical thiotepa in the treatment of newly diagnosed superficial bladder cancer."5.07The effect of intravesical thiotepa on tumour recurrence after endoscopic treatment of newly diagnosed superficial bladder cancer. A further report with long-term follow-up of a Medical Research Council randomized trial. Medical Research Council Working P ( , 1994)
"Twenty patients previously treated with surgery, radiation therapy and chemotherapy with a nitrosourea for malignant supratentorial gliomas received a combination of procarbazine, thiotepa and vincristine (P."5.07Treatment of recurrent malignant supratentorial gliomas with the association of procarbazine, thiotepa and vincristine: a phase II study. ( Ameri, A; Chen, QM; Delattre, JY; Poisson, M, 1993)
"This report presents the second interim analysis of data from a randomized prospective trial that compares the prophylactic effect of 15 intravesical instillations of 50 mg Doxorubicin (ADM), 50 mg of Thiotepa (TTPA), or 150 mg of Bacillus Calmette-Guérin (BCG) against recurrence and progression of superficial transitional cell bladder cancer."5.06Intravesical therapy comparing BCG, adriamycin, and thiotepa in 200 patients with superficial bladder cancer: a randomized prospective study. ( Cárcamo, P; Fiter, L; García Matres, MJ; Jimenez León, J; Martinez-Pineiro, JA; Martinez-Pineiro, L; Mosteiro, JA; Navarro, J, 1989)
"The National Bladder Cancer Group undertook a study to determine the effectiveness and toxicity of mitomycin in patients who failed on thiotepa."5.05Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group. ( Barton, B; Hazra, TA; Heney, NM; Kluskens, L; Koontz, WW; Soloway, MS; Trump, DL, 1985)
"The influence of the instillation of thiotepa or doxorubicin hydrochloride into the bladder at the end of transurethral surgical treatment on the recurrence of bladder cancer was evaluated."5.05Influence of thiotepa and doxorubicin instillation at time of transurethral surgical treatment of bladder cancer on tumor recurrence: a prospective, randomized, double-blind, controlled trial. ( Leary, FJ; Myers, RP; Taylor, WF; Utz, DC; Zincke, H, 1983)
"In a prospective, randomized, stratified study with crossover design the effect of thiotepa was compared to that of mitomycin C when each was instilled intravesically immediately at the end of complete removal of superficial bladder cancer (stages Ta and Tis) and later on tumor recurrence."5.05Intravesical thiotepa and mitomycin C treatment immediately after transurethral resection and later for superficial (stages Ta and Tis) bladder cancer: a prospective, randomized, stratified study with crossover design. ( Benson, RC; Hilton, JF; Taylor, WF; Zincke, H, 1985)
"This paper reports the preliminary results of an ongoing clinical trial in patients with category T1 bladder cancer who are randomized after transurethral resection to receive either thiotepa, VM-26, or no treatment."5.04Adjuvant therapy of T1 bladder carcinoma: preliminary results of an EORTC randomized study. ( De Pauw, M; Denis, L; Lachand, A; Pavone-Macaluso, M; Robinson, M; Schulman, C; Smith, P; Staquet, M; Sylvester, R, 1978)
"This report describes and presents some preliminary results from a prospective clinical investigation to determine the ablative effect of thiotepa (N,N',N''-triethylene phosphoramide) on superficial low-stage bladder cancer and the effectiveness of this agent in the prevention of recurrent or new tumors."5.04The role of intravesical thiotepa in the management of superficial bladder cancer. National Bladder Cancer Collaborative Group A. ( , 1977)
"Thiotepa-based conditioning followed by HSCT may be effective in most CNS lymphoma patients, with a manageable toxicity profile."4.90Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma. ( Bredeson, C; Fergusson, D; Kokolo, MB; O'Neill, J; Stewart, D; Tay, J; Tinmouth, AT, 2014)
"Mitomycin-C (MMC) and thiotepa are intravesical agents effective in reducing the recurrence of low-grade noninvasive bladder cancer when instilled perioperatively."3.91Single-dose perioperative mitomycin-C versus thiotepa for low-grade noninvasive bladder cancer. ( Blodgett, G; Castle, EP; Chang, YH; Etzioni, DA; Faraj, K; Habermann, EB; Humphreys, MR; Rose, KM; Tyson Ii, MD, 2019)
" The authors report long-term survival of a 1-year-old patient with recurrent CPC and Li-Fraumeni syndrome with surgical resection and high-dose chemotherapy (HDC) consisting of single cycle of Busulfan and Thiotepa followed by autologous stem cell rescue without the use of radiation therapy."3.79Successful treatment of a recurrent choroid plexus carcinoma with surgery followed by high-dose chemotherapy and stem cell rescue. ( Bartels, U; Bouffet, E; Huang, A; Mosleh, O; Schechter, T; Tabori, U, 2013)
"The aim of this study was to evaluate the efficacy and toxicity of two chemotherapy regimens based on platinum and cytarabine in association with etoposide and methylprednisolone (ESHAP) or with dexamethasone (DHAP) with or without Rituximab (± R) in patients with refractory or a relapsed Primary Central Nervous System Lymphoma (PCNSL)."3.77Platine and cytarabine-based salvage treatment for primary central nervous system lymphoma. ( Choquet, S; del Rio, MS; Fourme, E; Glaisner, S; Hoang-Xuan, K; Janvier, M; Soussain, C, 2011)
"Twenty-seven children and adolescents with malignant astrocytomas [17 glioblastoma multiforme and 10 anaplastic astrocytoma (AA)] following initial tumor progression, received myeloablative chemotherapy followed by autologous marrow rescue with one of three thiotepa and etoposide-based chemotherapy regimens, administered alone (n = 11) or combined with carmustine (n = 5) or carboplatin (n = 11)."3.74Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group. ( Boyett, JM; Dhall, G; Dunkel, IJ; Finlay, JL; Gardner, SL; Goldman, S; Packer, RJ; Pollack, IF; Rosenblum, MK; Stanley, P; Wallace, D; Yates, AJ; Zimmerman, RA, 2008)
" We report our experience with a 19-year-old girl with glioblastoma multiforme (GBM) of the deep temporal region recurring 6 months after completing an intensive treatment that included preradiation chemotherapy (chemotherapy as a preradiation "sandwich" phase) with a myeloablative course of thiotepa, tumor bed radiotherapy and postradiation maintenance chemotherapy."3.73A case of relapsing glioblastoma multiforme responding to vinorelbine. ( Biassoni, V; Casanova, M; Gandola, L; Massimino, M; Spreafico, F, 2006)
"Following local treatment and doxorubicin-containing standard chemotherapy, 42 patients with surgical Stage II or IIIA breast cancer containing ten or more involved axillary nodes and 13 patients with Stage IIIB disease were treated with high-dose chemotherapy (TMJ) consisting of thiotepa (750 mg/m2), mitoxantrone (40 mg/m2), and carboplatin (1000 mg/m2), with autologous bone marrow (ABM) and peripheral stem cell (PSC) transplant, followed by irradiation and/or hormone therapy."3.69TMJ: a well-tolerated high-dose regimen for the adjuvant chemotherapy of high risk breast cancer. ( Ahmed, T; Beer, M; Cook, P; Feldman, EJ; Lake, DE; Mittelman, A; Puccio, C; Razis, ED; Samonis, G, 1994)
"Twenty-one percent of responding metastatic breast cancer patients remain progression-free a median 50 months following one intensification cycle of cyclophosphamide (6,000 mg/m2), thiotepa (500 mg/ m2), and carboplatin (800 mg/m2) (CTCb) with autologous bone marrow transplantation (ABMT)."3.69Double dose-intensive chemotherapy with autologous stem-cell support for metastatic breast cancer: no improvement in progression-free survival by the sequence of high-dose melphalan followed by cyclophosphamide, thiotepa, and carboplatin. ( Antman, K; Ayash, LJ; Elias, A; Frei, E; Ibrahim, J; Lynch, C; Reich, E; Richardson, P; Schnipper, L; Schwartz, G; Teicher, BA; Warren, D; Wheeler, C, 1996)
"Fifty-three metastatic breast cancer patients were treated with a four-drug program of high-dose chemotherapy including cyclophosphamide (6 g/m2), thiotepa (500 mg/m2), carboplatin (800-1,600 mg/m2) and mitoxantrone (20-60 mg/m2) with autologous peripheral blood progenitor cell support followed by filgrastim."3.69[High-dose chemotherapy with four drugs and peripheral blood progenitor cell autologous transplantation in disseminated breast cancer]. ( Alonso, JL; Ayala, F; Casado, A; Díaz-Rubio, E; Llorente, L; López Martín, JA; Martín, M; Nieto, Y; Pérez Calvo, J; Pérez López, C; Rodríguez Lescure, A; Villegas, A, 1997)
"To further improve the effect of high-dose chemotherapy in the treatment of locally advanced and metastatic breast cancer, we sought to develop a second active high-dose noncross-resistant regimen to use in tandem with our customary high-dose regimen of cyclophosphamide, etoposide, and cisplatin (CVP)."3.68A phase II study of mitoxantrone, etoposide, and thiotepa with autologous marrow support for patients with relapsed breast cancer. ( Buzdar, A; Dunphy, F; Ewer, M; Holmes, F; Hortobagyi, G; Huan, S; Spitzer, G; Theriault, R; Wallerstein, R; Yau, J, 1990)
"One hundred patients suffering from advanced breast cancers and resisting to one (15) or several (85) drugs previously administered have been treated by an association of mitomycin C, thiotepa and vindesine, given every 3 weeks."3.66[Chemotherapy associating mitomycin C, thiotepa and vindesine in advanced breast cancers. Study of 100 cases (author's transl)]. ( Brunet, R; Bui, BN; Chauvergne, J; Durand, M; Hoerni, B; Mauriac, L, 1981)
"A course of combined therapy (adriablastin, cyclophosphan, vincristine and, in some cases, 5-fluorouracil) was given to 50 breast cancer patients with metastases of different localization."3.66[Combination chemotherapy including anablastine in disseminated breast cancer]. ( Ass, NIa; Dement'eva, IP; Lipovich, MM, 1981)
"Recurrent medulloblastoma is highly lethal in previously irradiated patients."2.75High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. ( Dunkel, IJ; Finlay, JL; Gardner, SL; Garvin, JH; Goldman, S; Shi, W, 2010)
" The tumours with a TOP2A amplification contributed hardly to this difference, suggesting that TOP2A amplification is not the cause of the steep dose-response curve for anthracyclines in breast cancer."2.72Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy. ( Bontenbal, M; de Vries, EG; Hannemann, J; Hupperets, P; Kristel, P; Nooij, MA; Rodenhuis, S; Smit, WM; van de Vijver, MJ; van der Wall, E; van Hoesel, QG; van Tinteren, H; Voest, EE, 2006)
"Twenty patients with recurrent brain tumors aged 0."2.69Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors. ( Boyett, JM; Dunkel, IJ; Finlay, JL; Gardner, S; Garvin, JH; Goldman, S; Gollamudi, S; Guruangan, S; Merchant, TE; Rosenblum, M, 1998)
"Patients with advanced epithelial ovarian cancer treated with salvage therapy using new combinations of systemic chemotherapy, radiation therapy, and systemic immunotherapy have had limited success."2.69A phase II study of intraperitoneal cisplatin and thiotepa in residual ovarian carcinoma: a Gynecologic Oncology Group study. ( Alvarez, RD; Berek, JS; Blessing, JA; DiSaia, PJ; Feun, LG; Major, FJ, 1998)
"Eleven patients with germ cell cancer relapsing from a complete remission and 7 patients with refractory germ cell cancer and/or an unresectable partial remission received salvage chemotherapy with one to two courses of carboplatin (800 mg/m2) and etoposide (500 mg/m2 on days 1, 3, and 5), followed by either one or two courses of carboplatin (1600 mg/m2), cyclophosphamide (6 g/m2), and thiotepa (480 mg/m2) divided over 4 days with autologous bone marrow transplantation and/or peripheral stem cell support."2.68Pilot study of a high-dose carboplatin-based salvage strategy for relapsing or refractory germ cell cancer. ( Richel, DJ; Rodenhuis, S; Schornagel, JH; ten Bokkel Huinink, WW; van der Wall, E; Vlasveld, LT, 1995)
"Women with metastatic breast cancer who had measurable disease, required laboratory tests, had received no prior chemotherapy for metastases, had a Cancer and Leukemia Group B (CALGB) performance status < or = 2, and provided informed consent were eligible."2.68Combination chemotherapy for metastatic or recurrent carcinoma of the breast--a randomized phase III trial comparing CAF versus VATH versus VATH alternating with CMFVP: Cancer and Leukemia Group B Study 8281. ( Abrams, J; Aisner, J; Budman, D; Cirrincione, C; Citron, M; Holland, J; Muss, H; Panasci, L; Perloff, M; Perry, M, 1995)
" Haematologic toxicity is greater in the CMF group, requiring more frequent dosage reductions."2.67Randomized trial of adjuvant chemotherapy for operable breast cancer comparing i.v. CMF to an epirubicin-containing regimen [see comment]. ( Bonichon, F; Chauvergne, J; Dilhuydy, JM; Durand, M; Mauriac, L, 1992)
"Fifty-eight patients with disseminated breast cancer were randomly divided into 2 study groups."2.66[Evaluation of regimens for the simultaneous and sequential administration of cytostatics in the combined chemotherapy of disseminated forms of breast cancer]. ( Borisov, AI; Korman, DB; Maslova, IA; Pines, EV, 1985)
"Superficial bladder cancer can be treated surgically, but patients are at high risk for recurrence."2.43Bladder cancer: current optimal intravesical treatment. ( Hale, K; Lamm, DL; McGee, WR, 2005)
"The management of superficial bladder cancer has advanced significantly in recent years."2.39BCG in perspective: advances in the treatment of superficial bladder cancer. ( Lamm, DL, 1995)
"7."2.38Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma. ( Jordan, AM; Murphy, WM; Soloway, MS, 1989)
"Management of the superficial bladder cancer patient consists of two complementary but separate therapeutic goals: treatment of the existing tumor(s) and prevention of tumor recurrence."2.37The biology and treatment of superficial bladder cancer. ( Lum, BL; Torti, FM, 1984)
"Most patients with bladder cancer initially present with localized, potentially curable tumours."2.36Treatment of superficial bladder cancer. ( Morales, A, 1980)
"All patients had high-risk hematologic malignancies, were younger than 20 years, and were in complete cytological remission at the time of allo-HSCT."1.91Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders. ( Andersson, BS; Anurathapan, U; Hongeng, S; Pakakasama, S; Pongpitcha, P; Sirachainan, N; Songdej, D; Tannumsaeung, S, 2023)
"Eleven patients with non-germinomatous germ cell tumors and nine patients with germinomas were enrolled."1.39Myeloablative chemotherapy and autologous stem cell transplantation in patients with relapsed or progressed central nervous system germ cell tumors: results of Korean Society of Pediatric Neuro-Oncology (KSPNO) S-053 study. ( Baek, HJ; Han, JW; Im, HJ; Kang, HJ; Koh, KN; Lee, SH; Park, HJ; Park, KD; Sung, KW, 2013)
"Paclitaxel has minimal penetration of the blood-brain barrier and central nervous system side effects are rare."1.35Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma. ( Fangusaro, J; Finlay, J; Rook, J; Rosser, T, 2008)
"A 56-year-old female with breast cancer after left partial mastectomy and subaxillary lymph node dissection was treated with adjuvant chemoradiotherapy."1.33[A case of recurrent breast cancer complicated with pericardial effusions and cardiac tamponade]. ( Ishiguro, A; Mitobe, S; Munakata, M; Okada, R; Sakata, Y; Shitara, K; Tomioka, R, 2006)
"Four cases had stage II or III breast cancer with over 10 positive axillary lymph nodes who had received radical surgical resection."1.30[Combination of high-dose chemotherapy with autologous hematopoietic stem cell transplantation for recurrent and high-risk breast cancer: a pilot study]. ( Han, X; Pan, F; Shi, Y, 1999)
"Medulloblastoma is a highly lethal disease when it recurs."1.30High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. Children's Cancer Group. ( Allen, JC; Bostrom, BC; Boyett, JM; Dunkel, IJ; Finlay, JL; Gardner, SL; Garvin, JH; Goldman, S; Li, H; Rosenblum, M; Sender, LS; Yates, A, 1998)
"Stage II patients with breast carcinoma who had undergone lumpectomy."1.28Adjuvant therapy of stage II breast cancer treated with CMFVP, radiation therapy and VATH following lumpectomy. A pilot trial. ( Allen, S; Bosworth, H; Budman, D; Lehrman, D; Lichtman, SM; Schulman, P; Vinciguerra, V; Weiselberg, L; Weiss, R, 1991)
"One hundred fifty-five patients with urinary bladder cancer who were not suitable for radical surgery were treated with full-course radiotherapy, 6600 cGy in 9 weeks, split-course."1.28Recurrence and treatment of urinary bladder cancer after failure in radiotherapy. ( Salminen, E, 1990)
"Superficial bladder cancer has a good prognosis compared with invasive bladder cancer."1.28[Superficial bladder cancer: prophylaxis of recurrence and progression]. ( Akaza, H; Koiso, K; Miyanaga, N, 1991)
" These patients with progressive bladder carcinoma appeared to be unaffected by intravesical thiotepa in the dosage used."1.27Intravesical thiotepa prophylaxis of superficial bladder cancer. A follow-up study. ( Fosså, SD; Miller, A; Stenwig, AE, 1983)
"The incidence of bladder cancer is slowly rising, which may be due in part to the increasing use of chemicals in every phase of our modern society."1.27Bladder cancer. Management of an increasingly common tumor. ( Soloway, MS, 1983)
"Thiotepa has been used clinically for greater than 30 years but its pharmacokinetics remain poorly defined."1.27Human plasma pharmacokinetics and urinary excretion of thiotepa and its metabolites. ( Aisner, J; Cohen, BE; Egorin, MJ; Gutierrez, PL; Kohlhepp, EA, 1986)
"Recurrent bladder tumors developed subsequently in 80 per cent of the patients in group 1, 42."1.27A comparison of treatment methods for the prophylaxis of recurrent superficial bladder tumors. ( Lemos, GC; Rodrigues Netto Júnior, N, 1983)
"Out of 3718 breast cancer patients treated at Petrov Research Institute of Oncology 262 patients [7%] proved to have minimal (less than 1 cm in diameter) form of breast cancer."1.27Minimal breast cancer. Clinical characteristics and treatment results. ( Orlov, AA; Pavlov, KA; Semiglazov, VF, 1983)
"A case of distant metastases of a giant cell tumor of the radius is presented."1.27Extensive distal subcutaneous metastases of a "benign" giant cell tumor of the radius. ( Muirragui, A; Serra, JM; Tadjalli, H, 1985)
"Patients with recurrent superficial bladder tumors have been treated by vesical and intradermal administration of Bacillus Calmette-Guerin."1.26Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors. ( Bruce, AW; Eidinger, D; Morales, A, 1976)
" Continuing maintenance therapy was required in the majority but, with the passage of time, the dosage could be progressively reduced, suggesting a cumulative effect of treatment."1.26Early multiple-dose adjuvant thiotepa in the control of multiple and rapid T1 tumour neogenesis. ( Blandy, JP; England, HR; Flynn, JT; Paris, AM, 1981)
"Recurrent transitional cell carcinoma was treated with prophylactic intravesical thio-tepa in 22 cases."1.26Intravesical thio-tepa in the immediate postoperative period in patients with recurrent transitional cell carcinoma of the bladder. ( Gavrell, GJ; Leblanc, GA; Lewis, RW; Meehan, WL, 1978)
"Serious leukopenia was found in 2 of the 48 patients receiving the combined instillation therapy but we concluded that this was not attributable to the use of urokinase."1.25The prophylactic use of thio-tepa and urokinase in transitional cell carcinoma of the bladder: a preliminary report. ( Hisazumi, H; Misaki, T; Miyazaki, K; Naito, K; Uchibayashi, T, 1975)

Research

Studies (256)

TimeframeStudies, this research(%)All Research%
pre-1990148 (57.81)18.7374
1990's47 (18.36)18.2507
2000's32 (12.50)29.6817
2010's18 (7.03)24.3611
2020's11 (4.30)2.80

Authors

AuthorsStudies
Schenone, L1
Houillier, C1
Tanguy, ML1
Choquet, S3
Agbetiafa, K1
Ghesquières, H1
Damaj, G1
Schmitt, A1
Bouabdallah, K1
Ahle, G1
Gressin, R1
Cornillon, J1
Houot, R1
Marolleau, JP1
Fornecker, LM1
Chinot, O1
Peyrade, F1
Bouabdallah, R1
Moluçon-Chabrot, C1
Gyan, E1
Chauchet, A1
Casasnovas, O2
Oberic, L1
Delwail, V1
Abraham, J1
Roland, V1
Waultier-Rascalou, A1
Willems, L1
Morschhauser, F1
Fabbro, M1
Ursu, R1
Thieblemont, C1
Jardin, F1
Tempescul, A1
Malaise, D1
Touitou, V1
Nichelli, L1
Le Garff-Tavernier, M1
Plessier, A1
Bourget, P1
Bonmati, C1
Wantz-Mézières, S1
Giordan, Q1
Dorvaux, V1
Charron, C1
Jabeur, W1
Hoang-Xuan, K4
Taillandier, L2
Soussain, C4
Finke, J2
Schmoor, C1
Stelljes, M1
Burchert, A1
Dreger, P1
Hegenbart, U1
Wagner-Drouet, EM1
Bornhäuser, M1
Sohlbach, K1
Schub, N1
Reicherts, C1
Kobbe, G1
Glass, B1
Bertz, H1
Grishina, O2
Tannumsaeung, S3
Anurathapan, U3
Pakakasama, S3
Pongpitcha, P3
Songdej, D3
Sirachainan, N3
Andersson, BS3
Hongeng, S3
Othman, T1
Quan, MA1
Zhang, S1
Gaut, D1
Young, PA1
Mahmood, O1
Abdulhaq, H1
Shieh, K1
Reid, J1
Brem, EA1
Hariharan, N1
Heyman, B1
Tuscano, J1
Arshad, S1
Fang, X1
Ahn, KW2
Kaur, M1
Scordo, M2
Sauter, CS3
Furqan, F1
Awan, FT2
Hamadani, M2
Alderuccio, JP1
Nayak, L1
Cwynarski, K1
Faraj, K1
Chang, YH1
Rose, KM1
Habermann, EB1
Etzioni, DA1
Blodgett, G1
Castle, EP1
Humphreys, MR1
Tyson Ii, MD1
Peric, Z1
Mohty, R1
Bastos, J1
Brissot, E1
Battipaglia, G1
Belhocine, R1
Sestili, S1
Giannotti, F1
Vekhoff, A1
Ledraa, T1
Legrand, O1
Lapusan, S1
Isnard, F1
Labopin, M1
Bonnin, A1
Mediavilla, C1
Rubio, MT1
Ruggeri, A1
Duléry, R1
Malard, F1
Mohty, M1
de Boo, L1
Cimino-Mathews, A1
Lubeck, Y1
Daletzakis, A1
Opdam, M1
Sanders, J3
Hooijberg, E1
van Rossum, A1
Loncova, Z1
Rieder, D1
Trajanoski, Z1
Vollebergh, M1
Sobral-Leite, M1
van de Vijver, K1
Broeks, A1
van der Wiel, R1
van Tinteren, H3
Linn, S1
Horlings, HM1
Kok, M1
Ma, Y1
Lim, DH1
Cho, H1
Lee, JW2
Sung, KW2
Yoo, KH1
Koo, HH1
Shin, HJ1
Suh, YL1
Wang, TP1
Chen, Y1
Ahmed, S1
Beitinjaneh, A1
Chen, A1
Chow, VA1
Dholaria, B1
Epperla, N1
Farooq, U1
Ghosh, N1
Grover, N1
Hamad, N1
Hildebrandt, GC1
Holmberg, L1
Hong, S1
Inwards, DJ1
Jimenez-Jimenez, A1
Karmali, R1
Kenkre, VP1
Khimani, F1
Klyuchnikov, E1
Krem, MM1
Munshi, PN1
Nieto, Y2
Prestidge, T1
Ramakrishnan Geethakumari, P1
Rezvani, AR1
Riedell, PA1
Seo, S1
Shah, NN1
Solh, M1
Yared, JA1
Kharfan-Dabaja, MA1
Herrera, A1
Takahashi, M1
Sumitani, R1
Hori, T1
Murai, J1
Kawata, S1
Oura, M1
Sogabe, K1
Harada, T1
Fujii, S1
Miki, H1
Kagawa, K1
Abe, M1
Nakamura, S1
Lafrenie, RM1
Speigl, L1
Buckner, CA1
Pawelec, G1
Conlon, MS1
Shipp, C1
Baek, HJ1
Park, HJ1
Lee, SH1
Han, JW1
Koh, KN1
Im, HJ1
Kang, HJ1
Park, KD1
Chen, F1
Chen, K1
Kokolo, MB1
Fergusson, D1
O'Neill, J1
Tay, J1
Tinmouth, AT1
Stewart, D2
Bredeson, C1
Welch, MR1
Matasar, MJ1
Faivre, G1
Weaver, SA1
Moskowitz, CH1
Omuro, AM1
Sylvester, RJ1
Oosterlinck, W2
Holmang, S1
Sydes, MR1
Birtle, A1
Gudjonsson, S1
De Nunzio, C1
Okamura, K1
Kaasinen, E1
Solsona, E1
Ali-El-Dein, B1
Tatar, CA1
Inman, BA1
N'Dow, J1
Oddens, JR1
Babjuk, M1
Dardis, C1
Milton, K1
Ashby, L1
Lee, MY1
Kim, HS1
Lee, JY1
Lim, SH1
Kang, ES1
Ko, YH1
Kim, SJ1
Kim, WS1
Schorb, E1
Ferreri, AJ1
Ihorst, G1
Mikesch, K1
Kasenda, B1
Fritsch, K1
Fricker, H1
Burger, E1
Valk, E1
Zucca, E1
Illerhaus, G1
Lu, DD1
Boorjian, SA1
Raman, JD1
Finlay, JL7
Dhall, G2
Boyett, JM4
Dunkel, IJ7
Gardner, SL3
Goldman, S5
Yates, AJ2
Rosenblum, MK2
Stanley, P2
Zimmerman, RA2
Wallace, D1
Pollack, IF1
Packer, RJ4
Massimino, M2
Gandola, L2
Spreafico, F2
Biassoni, V2
Luksch, R1
Collini, P1
Solero, CN1
Simonetti, F1
Pignoli, E1
Cefalo, G1
Poggi, G1
Modena, P1
Mariani, L1
Potepan, P1
Podda, M1
Casanova, M2
Pecori, E1
Acerno, S1
Ferrari, A1
Terenziani, M1
Meazza, C1
Polastri, D1
Ravagnani, F1
Fossati-Bellani, F1
Grodman, H1
Wolfe, L1
Kretschmar, C1
Butturini, AM1
Jacob, M1
Aguajo, J1
Vander-Walde, NA1
Villablanca, J1
Jubran, R1
Erdreich-Epstein, A1
Marachelian, A1
Gilheeney, SW1
Khakoo, Y1
Souweidane, M1
Wolden, S1
Boulad, F1
Garvin, JH3
Shi, W1
Daveau, C1
Savignoni, A1
Abrous-Anane, S1
Pierga, JY1
Reyal, F1
Gautier, C1
Kirova, YM1
Dendale, R1
Campana, F1
Fourquet, A1
Bollet, MA1
del Rio, MS1
Glaisner, S1
Fourme, E2
Janvier, M2
Miura, Y1
Toyooka, N1
Iwai, F1
Matsui, Y1
Hirai, M1
Kaneko, H1
Watanabe, M1
Tsudo, M1
Fay, MP1
Shih, JH1
Mosleh, O1
Tabori, U1
Bartels, U1
Huang, A1
Schechter, T1
Bouffet, E2
Rodenhuis, S3
Bontenbal, M2
Beex, LV1
Wagstaff, J1
Richel, DJ2
Nooij, MA2
Voest, EE2
Hupperets, P2
Peterse, HL1
TenVergert, EM1
de Vries, EG2
Tallman, MS1
Gray, R2
Robert, NJ1
LeMaistre, CF1
Osborne, CK1
Vaughan, WP1
Gradishar, WJ1
Pisansky, TM1
Fetting, J1
Paietta, E1
Lazarus, HM1
GRECO, T1
HANKINS, GW1
MCCARTEN, AB1
IMANAGA, H1
EDELSTYN, GA1
COLE, WH1
ROBERTS, SS1
WEBB, RS1
STREHL, FW1
OATES, GD1
Fagioli, F1
Biasin, E1
Mastrodicasa, L1
Sandri, A1
Ferrero, I1
Berger, M1
Vassallo, E1
Madon, E1
Modak, S2
Gardner, S3
Balmaceda, C3
Miller, DC2
Halpern, S1
Campbell, AD1
Cohn, SL1
Reynolds, M1
Seshadri, R1
Morgan, E1
Geissler, G1
Rademaker, A1
Marymount, M1
Kalapurakal, J1
Haut, PR1
Duerst, R1
Kletzel, M1
Shim, BY1
Lee, MA1
Byun, JH1
Roh, SY1
Song, CW1
Park, JN1
Min, WS1
Hong, YS1
Kim, CC1
Pérez-Martínez, A1
Lassaletta, A1
González-Vicent, M1
Sevilla, J1
Díaz, MA1
Madero, L1
Lamm, DL3
McGee, WR1
Hale, K1
Kushner, BH1
Kramer, K1
Kernan, NA1
Reich, LM1
Danis, K1
Cheung, NK1
Stern, BV1
Baehring, JM1
Kleopa, KA1
Hochberg, FH1
Shitara, K1
Munakata, M1
Ishiguro, A1
Okada, R1
Tomioka, R1
Mitobe, S1
Sakata, Y1
Zacharoulis, S1
Levy, A1
Chi, SN1
Rosenblum, M3
Dunkel, I1
Diez, B1
Sposto, R1
Ji, L1
Asgharzadeh, S1
Hukin, J1
Belasco, J1
Dubowy, R1
Kellie, S1
Termuhlen, A1
Finlay, J2
Rook, J1
Rosser, T1
Fangusaro, J1
Hannemann, J1
Kristel, P1
van Hoesel, QG1
Smit, WM1
van der Wall, E2
van de Vijver, MJ1
Ridola, V1
Grill, J2
Doz, F3
Gentet, JC1
Frappaz, D1
Raquin, MA1
Habrand, JL1
Sainte-Rose, C2
Valteau-Couanet, D2
Kalifa, C3
Izumi, K1
Kanno, H1
Umemoto, S1
Hasumi, H1
Osada, Y1
Otai, J1
Mikata, K1
Tsuchiya, F1
Nagashima, Y1
Choi, LM1
Rood, B1
Kamani, N1
La Fond, D1
Santi, MR1
Macdonald, TJ1
Gill, P1
Litzow, M1
Buckner, J1
Arndt, C1
Moynihan, T1
Christianson, T1
Ansell, S1
Galanis, E1
Witz, F1
Dupriez, B1
Souleau, B1
Taksin, AL1
Gisselbrecht, C1
Jaccard, A1
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Sanson, M1
Kolb, B1
Zini, JM1
Leblond, V2
Semiglazov, VF2
Pavlov, KA1
Orlov, AA2
Rodrigues Netto Júnior, N1
Lemos, GC1
Soloway, MS8
Zincke, H2
Utz, DC1
Taylor, WF2
Myers, RP1
Leary, FJ1
Cohen, CJ1
Goldberg, JD1
Holland, JF1
Bruckner, HW1
Deppe, G1
Gusberg, SB1
Wallach, RC1
Kabakow, B1
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Alonso, M2
Moreno, B2
Jiménez, JF3
Lancina Martín, J1
Monsalve Rodríguez, M1
Gómez Cisneros, S1
García Alonso, J1
Zhang, SX1
Deng, XZ1
Tang, XD1
Levin, DR1
Moskovitz, B1
Mazeman, E1
Rigot, JM1
Cracco, D1
Sauvage, L1
Sánchez, A1
Martínez, R1
Vera, CD1
Yoshida, K1
Yamada, K1
Aoyama, H1
Hashimoto, M1
Alter, AJ1
Malek, GH1
Gilloz, A1
Sauvage, I1
Gremillet, E1
Héritier, P1
Richard, A1
el Hajj, E1
Diez-Yanguas, J1
Novak, R1
Kern, J1
Fister, H1
Trnski, D1
Dimanovski, J1
Kraus, O1
Serra, JM1
Muirragui, A1
Tadjalli, H1
Korman, DB1
Borisov, AI1
Maslova, IA1
Pines, EV1
Heney, NM1
Kluskens, L1
Hazra, TA1
Trump, DL1
Barton, B1
Haas, JA1
Benson, RC1
Hilton, JF1
Richard, JM1
Sancho, H1
Griffen, WO1
Humphrey, L1
Sosin, H1
Sokolova, VD1
Sharoukhova, KS1
Goncharova, MG1
Murav'eva, NI1
Smirnova, KD1
Schellhammer, PF1
Rutishauser, G1
Klein, U1
Tuchschmid, D1
Luzuy, R1
Bouzakoura, C1
Lunglmayr, G2
Czech, K1
Zekert, F1
Kellner, G1
Kierfeld, G1
Mellin, P1
Veenema, RJ2
Romas, NA1
Fingerhut, B1
Donegan, WL2
Wise, L1
Corrado, F1
Lalanne, G1
Pizza, GC1
Caramia, G2
Rizzo, FP2
Rybalka, AN1
Mardakhiashvili, ShI1
Furnari, S1
Veroux, G1
Mattea, E1
Garin, AM1
Karev, NI1
Bazhenova, AP1
Blokhina, NG1
Balas, AN1
Rausa, L1
Gebbia, N1
Arena, E1
Tessitore, V1
Vecchioni, M1
Deutsch, M1
Parsons, JA1
Atkins, H1
Hayward, JL1
Klugman, DJ1
Wayte, AB1
Golomb, FM1
Hill, GJ1
Larsen, RR1
Humphrey, LJ1
Jewell, WR1
Watne, AL1
Covey, TH1
Zingg, E1
Sulmoni, A1
Oravisto, KJ1
Spitalier, JM1
Amalric, R1
Ayme, Y1
Desgeorge, Y1
Pollet, JF1
Fish, J1
Smith, EB1
Canby, JP1
Wescott, JW1
Decker, DG1
Malkasian, GD1
Mussey, E1
Johnson, CE1
Smith, JP1
Rutledge, F1
Burns, BC1
Soffar, S1
Holden, WD1
Dixon, WJ1
Kuzma, JW1
Ansfield, FJ1
Watkins, WE1
Kozak, JA1
Flanagan, MJ1
Reuter, JH1
Denk, W1
Vishniakova, EG1
Drew, JE1
Marshall, VF1
Fisher, B4
Ravdin, RG3
Ausman, RK1
Slack, NH4
Moore, GE1
Noer, RJ1
Hall, TC1
Cohn, I1
Dean, AL1
Uson, AC1
Roberts, M1
Longo, F1
Long, RT1
Evans, AM1
Getzen, LC1
Leipe, ER1
Utsunomia, J1
Hishiki, S1
Nakamura, T1
Reilly, MM1
Fitzpatrick, PJ1
Blumenson, LE1
Bross, ID1
Moore, FT1
Andrews, NC1
Cavanaugh, PJ1
Gardner, B2
Lewison, EF1
Dao, TL1
State, D1
Riddle, PR1
Wallace, DM1
Mitchell, RJ1
Smirnova, IN1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Cohort Study of Transurethral Resection of Bladder Tumor (TURBT) Combined With Adjuvant Intravenous GC Chemotherapy to Prevent Moderate-high Recurrence and Progression Risks of Muscle-invasive Bladder Cancer[NCT02716961]208 participants (Anticipated)Interventional2016-01-31Recruiting
High-dose Chemotherapy and Autologous Stem Cell Transplant or Consolidating Conventional Chemotherapy in Primary CNS Lymphoma - Randomized Phase III Trial[NCT02531841]Phase 3250 participants (Anticipated)Interventional2014-07-31Recruiting
A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors[NCT02653196]Early Phase 11 participants (Actual)Interventional2015-09-30Terminated (stopped due to The Principal Investigator left the institution.)
A Prospective Randomized Feasibility and Phase II Adjuvant Breast Cancer Study of the Netherlands Working Party for Autotransplantation in Solid Tumors.[NCT00851110]Phase 250 participants (Anticipated)Interventional2004-10-31Terminated
High-dose Chemotherapy With Hematopoietic Stem-cell Rescue for High-risk Breast Cancer: Long-term Follow-up of a Randomized Phase III Study[NCT03087409]885 participants (Actual)Observational2016-07-31Completed
A Phase 2a Study of the Addition of Temozolomide to a Standard Conditioning Regimen for Autologous Stem Cell Transplantation in Relapsed and Refractory Central Nervous System (CNS) Lymphoma[NCT01235793]Phase 211 participants (Actual)Interventional2010-10-14Terminated (stopped due to The clinical trial was terminated due to poor enrollment)
A Phase III Multicenter Study of Intratumoral/Interstitial Therapy With TransMID Compared to Best Standard of Care in Patients With Progressive and/or Recurrent, Non-Resectable Glioblastoma Multiforme[NCT00088400]Phase 330 participants Interventional2004-07-31Completed
Efficacy and Tolerance Adjuvant High-Dose Thiotepa With Peripheral Stem Cell Rescue Associated With Conventional Chemotherapy in Children and Adults With Relapsed Osteosarcoma[NCT00978471]Phase 244 participants (Actual)Interventional2009-07-31Completed
A Phase I Trial of Busulfan, Thiotepa and Melphalan Followed by Autologous or Syngeneic Peripheral Blood Stem Cell Transplantation and Followed by Total Marrow (Skeletal) Irradiation (TMI) in Patients With High-Risk Ewing's Sarcoma, PNET or Rhabdomyosarco[NCT00003081]Phase 116 participants (Anticipated)Interventional1998-03-31Completed
Intravesical Instillation Therapy With Bacillus Calmette-Guérin (BCG) and Sequential BCG and Electromotive Mitomycin-C (EMDA-MCC) in Patients With High-risk Non-muscle-invasive Bladder Carcinoma[NCT03664869]Phase 3300 participants (Anticipated)Interventional2018-10-26Recruiting
The Difference of Two Year Recurrence Rate According to Anesthetic Method During Transurethral Resection of Bladder Mass in Patients With Non-muscle Invasive Bladder Cancer: Prospective, Randomized, Clinical Phase II Study[NCT03597087]289 participants (Anticipated)Interventional2018-07-19Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Safest Dose of Temozolomide for the DRBEAT Regimen

Safety will be assessed using a dose escalation design for temozolomide's use to determine the target dose and also to evaluate any and all acute treatment related toxicities. During the course of patient follow up and therapy, toxicities will be evaluated, particularly as the investigators will be determining the target dose of temozolomide. One of the major criteria for dose limiting toxicity for the study will be any Grade 3 or 4 nonhematologic toxicity from a list of commonly expected toxicities associated with autologous transplantation and temozolomide. (NCT01235793)
Timeframe: One Year

Interventiondose in mg/m^2 (Number)
DRBEAT Regimen773.25

One-year Progression-free Survival and Overall Survival

"Efficacy of the DRBEAT Regimen will be assessed by analysis of~one-year progression-free survival (PFS), defined as the time interval from maximal response from therapy to tumor regrowth, progression*, or death, (*Progression is defined as meeting the response criteria listed in Table 4: Response Criteria for Primary Central Nervous System Lymphoma according to Abrey LE, Batchelor TT, Ferreri AJM et al.)~and~Overall survival, defined as the time interval between the date of transplant and the date of death from any cause." (NCT01235793)
Timeframe: (1) One Year (2) Until date of death from any cause, assessed up to 2 years

InterventionDays (Median)
Progression Free SurvivalOverall Survival
DRBEAT Regimen132564

Reviews

24 reviews available for thiotepa and Local Neoplasm Recurrence

ArticleYear
Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:12

    Topics: Central Nervous System Neoplasms; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Tran

2014
Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa-pT1 Urothelial Carcinoma
    European urology, 2016, Volume: 69, Issue:2

    Topics: Administration, Intravesical; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitiona

2016
Bladder cancer: current optimal intravesical treatment.
    Urologic nursing, 2005, Volume: 25, Issue:5

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Cystectomy

2005
Intravesical chemotherapy of superficial bladder cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 85

    Topics: Absorption; Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma in Situ; Doxorubicin; Endoscopy;

1983
The biology and treatment of superficial bladder cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; BCG Vaccine; Carcinoma, Squamous Cell; Carcinoma, Trans

1984
Intravesical chemotherapy in the management of superficial bladder tumors.
    Progress in clinical and biological research, 1984, Volume: 153

    Topics: Antineoplastic Agents; BCG Vaccine; Doxorubicin; Humans; Mitomycins; Neoplasm Recurrence, Local; Thi

1984
Rationale for intensive intravesical chemotherapy.
    Progress in clinical and biological research, 1984, Volume: 153

    Topics: Antineoplastic Agents; BCG Vaccine; Humans; Mitomycins; Neoplasm Recurrence, Local; Thiotepa; Urinar

1984
Intravesical chemotherapy.
    Progress in clinical and biological research, 1984, Volume: 162B

    Topics: Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Clinical Trials as Topic; Combined

1984
Intravesical and systemic chemotherapy in the management of superficial bladder cancer.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:4

    Topics: Administration, Topical; Aged; Antineoplastic Agents; Biopsy; Carcinoma, Transitional Cell; Cisplati

1984
Rationale for intensive intravesical chemotherapy for superficial bladder cancer.
    The Journal of urology, 1980, Volume: 123, Issue:4

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Doxorubicin; Humans; Mito

1980
Treatment of superficial bladder cancer.
    Canadian Medical Association journal, 1980, May-24, Volume: 122, Issue:10

    Topics: Aged; Antineoplastic Agents; BCG Vaccine; Cystoscopy; Humans; Immunotherapy; Male; Methods; Neoplasm

1980
[Progress in the internist treatment of bladder tumors].
    Wiener medizinische Wochenschrift (1946), 1982, Jul-31, Volume: 132, Issue:13-14

    Topics: Antineoplastic Agents; BCG Vaccine; Cisplatin; Doxorubicin; Ethoglucid; Humans; Leucovorin; Methotre

1982
[Treatment strategy to obtain cure for recurrent advanced breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carbo

1994
BCG in perspective: advances in the treatment of superficial bladder cancer.
    European urology, 1995, Volume: 27 Suppl 1

    Topics: Administration, Intravesical; BCG Vaccine; Doxorubicin; Humans; Mitomycin; Neoplasm Recurrence, Loca

1995
[High-dose chemotherapy in relapse of medulloblastoma in young children].
    Bulletin du cancer, 1997, Volume: 84, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cerebellar Ne

1997
Optimal BCG treatment of superficial bladder cancer as defined by American trials.
    European urology, 1992, Volume: 21 Suppl 2

    Topics: Administration, Intravesical; Administration, Oral; BCG Vaccine; Carcinoma in Situ; Carcinoma, Trans

1992
Graft versus host disease prophylaxis today.
    Bone marrow transplantation, 1991, Volume: 7 Suppl 2

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide

1991
Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma.
    Progress in clinical and biological research, 1989, Volume: 310

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma in Situ; Carcinoma, Tran

1989
BCG versus thiotepa in non-CIS, stage Ta, T1 bladder cancer: rationale and design of ECOG trial.
    Progress in clinical and biological research, 1989, Volume: 310

    Topics: Aged; BCG Vaccine; Carcinoma in Situ; Carcinoma, Transitional Cell; Doxorubicin; Female; Humans; Mal

1989
Intravesical therapy for bladder cancer.
    The Urologic clinics of North America, 1988, Volume: 15, Issue:4

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Cystoscopy; Doxorubicin; Female; H

1988
The prognosis and management of recurrent abdominal malignancies.
    Current problems in surgery, 1969

    Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Ca

1969
Chemotherapy for bladder cancer.
    Urology, 1974, Volume: 3, Issue:2

    Topics: Administration, Topical; Alkylating Agents; Blood Cell Count; Carcinoma, Papillary; Cystitis; Cystos

1974
Controversies in the management of potentially curable breast cancer.
    Surgery annual, 1974, Volume: 6

    Topics: Breast Neoplasms; Castration; Clinical Trials as Topic; England; Female; Fluorouracil; Humans; Lymph

1974
Chemotherapy of breast cancer.
    Clinical obstetrics and gynecology, 1968, Volume: 11, Issue:2

    Topics: Adrenal Cortex Hormones; Alkaloids; Alkylating Agents; Androgens; Antimetabolites; Antineoplastic Ag

1968

Trials

73 trials available for thiotepa and Local Neoplasm Recurrence

ArticleYear
Thiotepa-fludarabine-treosulfan conditioning for 2nd allogeneic HCT from an alternative unrelated donor for patients with AML: a prospective multicenter phase II trial.
    Bone marrow transplantation, 2022, Volume: 57, Issue:11

    Topics: Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Rec

2022
Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 127

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Prote

2020
High-dose chemotherapy and autologous stem cell transplant compared with conventional chemotherapy for consolidation in newly diagnosed primary CNS lymphoma--a randomized phase III trial (MATRix).
    BMC cancer, 2016, Apr-21, Volume: 16

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2016
Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous system.
    Pediatric blood & cancer, 2010, Volume: 54, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neop

2010
High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cerebellar Neoplasms

2010
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
    The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

2003
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
    The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

2003
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
    The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

2003
High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
    The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

2003
Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer.
    The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyc

2003
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cerebel

2005
Topotecan, thiotepa, and carboplatin for neuroblastoma: failure to prevent relapse in the central nervous system.
    Bone marrow transplantation, 2006, Volume: 37, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cent

2006
Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy.
    British journal of cancer, 2006, Nov-20, Volume: 95, Issue:10

    Topics: Adult; Anthracyclines; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarker

2006
Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-20, Volume: 26, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Busulfan; Combined Mod

2008
Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-20, Volume: 26, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Busulfan; Combined Mod

2008
Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-20, Volume: 26, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Busulfan; Combined Mod

2008
Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-20, Volume: 26, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Busulfan; Combined Mod

2008
Influence of thiotepa and doxorubicin instillation at time of transurethral surgical treatment of bladder cancer on tumor recurrence: a prospective, randomized, double-blind, controlled trial.
    The Journal of urology, 1983, Volume: 129, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Doxorubicin; Female; Humans; Male; Middl

1983
Improved therapy with cisplatin regimens for patients with ovarian carcinoma (FIGO Stages III and IV) as measured by surgical end-staging (second-look operation).
    American journal of obstetrics and gynecology, 1983, Apr-15, Volume: 145, Issue:8

    Topics: Aged; Antineoplastic Agents; Carcinoma; Cell Differentiation; Cisplatin; Clinical Trials as Topic; D

1983
Prognostic factors in superficial bladder tumors. A study of the European Organization for Research on Treatment of Cancer: Genitourinary Tract Cancer Cooperative Group.
    The Journal of urology, 1983, Volume: 129, Issue:4

    Topics: Humans; Neoplasm Recurrence, Local; Prognosis; Teniposide; Thiotepa; Urinary Bladder Neoplasms

1983
Long-term fate of 90 patients with superficial bladder cancer randomly assigned to receive or not to receive thiotepa.
    The Journal of urology, 1983, Volume: 130, Issue:4

    Topics: Aged; Carcinoma, Transitional Cell; Female; Follow-Up Studies; Humans; Male; Neoplasm Recurrence, Lo

1983
Bladder cancer chemotherapy studies supported by the National Bladder Cancer Project.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Papillary; Ci

1983
Cooperative studies of chemoprophylaxis after transurethral resection of bladder tumors.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Antineoplastic Agents; Carcinoma, Papillary; Cisplatin; Clinical Trials as Topic; Combined Modality

1983
Intravesical chemotherapy.
    Progress in clinical and biological research, 1984, Volume: 162B

    Topics: Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Clinical Trials as Topic; Combined

1984
Intravesical treatment with thiotepa: an update review.
    Progress in clinical and biological research, 1984, Volume: 162B

    Topics: Carcinoma, Transitional Cell; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neoplasm

1984
Resume of selected studies of the National Bladder Cancer Collaborative Group A and new protocols.
    Progress in clinical and biological research, 1984, Volume: 162B

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Cisplatin; Clini

1984
Prophylactic chemotherapy of superficial transitional cell bladder carcinoma: an EORTC randomized trial comparing thiotepa, an epipodophyllotoxin (VM26) and TUR alone.
    European urology, 1982, Volume: 8, Issue:4

    Topics: Carcinoma, Transitional Cell; Clinical Trials as Topic; Follow-Up Studies; Humans; Neoplasm Recurren

1982
Experience with bacillus Calmette-Guerin in patients with superficial bladder carcinoma.
    The Journal of urology, 1982, Volume: 128, Issue:1

    Topics: BCG Vaccine; Carcinoma in Situ; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Neo

1982
Pilot study of a high-dose carboplatin-based salvage strategy for relapsing or refractory germ cell cancer.
    Cancer investigation, 1995, Volume: 13, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Com

1995
Combination chemotherapy for metastatic or recurrent carcinoma of the breast--a randomized phase III trial comparing CAF versus VATH versus VATH alternating with CMFVP: Cancer and Leukemia Group B Study 8281.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cy

1995
The effect of intravesical thiotepa on tumour recurrence after endoscopic treatment of newly diagnosed superficial bladder cancer. A further report with long-term follow-up of a Medical Research Council randomized trial. Medical Research Council Working P
    British journal of urology, 1994, Volume: 73, Issue:6

    Topics: Administration, Intravesical; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cystoscopy; Drug

1994
Treatment of recurrent malignant supratentorial gliomas with the association of procarbazine, thiotepa and vincristine: a phase II study.
    Journal of neuro-oncology, 1993, Volume: 17, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Glioma; Humans; Male; Middle Ag

1993
Predictors of survival following relapse or progression of small cell lung cancer. Southwest Oncology Group Study 8605 report and analysis of recurrent disease data base.
    Cancer, 1993, Aug-15, Volume: 72, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide

1993
Maintenance tamoxifen after induction postoperative chemotherapy in node-positive breast cancer patients: the Eastern Cooperative Oncology Group Trials.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1993, Volume: 127

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosp

1993
A phase II evaluation of thiotepa in pediatric central nervous system malignancies.
    Cancer, 1993, Jul-01, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Drug Administrati

1993
ThioTEPA pharmacokinetics during intravesical chemotherapy: the influence of dose and volume of instillate on systemic uptake and dose rate to the tumour.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:1

    Topics: Absorption; Administration, Intravesical; Aged; Analysis of Variance; Antineoplastic Agents, Alkylat

1996
Contemporary chemotherapy issues for children with brainstem gliomas.
    Pediatric neurosurgery, 1996, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Brain Stem; Carboplatin; Carmustine; Dose-Response Relations

1996
A high-dose busulfan-thiotepa combination followed by autologous bone marrow transplantation in childhood recurrent ependymoma. A phase-II study.
    Pediatric neurosurgery, 1996, Volume: 25, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neopl

1996
Thiotepa and etoposide treatment of recurrent malignant gliomas: phase I study.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Etoposide;

1997
Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carbop

1998
A phase II study of intraperitoneal cisplatin and thiotepa in residual ovarian carcinoma: a Gynecologic Oncology Group study.
    Gynecologic oncology, 1998, Volume: 71, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Humans; Infusions, P

1998
A phase I study of high-dose BCNU, etoposide and escalating-dose thiotepa (BTE) with hematopoietic progenitor cell support in adults with recurrent and high-risk brain tumors.
    Journal of neuro-oncology, 1999, Volume: 44, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined

1999
Busulfan, melphalan, and thiotepa with or without total marrow irradiation with hematopoietic stem cell rescue for poor-risk Ewing-Sarcoma-Family tumors.
    Medical and pediatric oncology, 2000, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2000
Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Feb-01, Volume: 19, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neoplasms; C

2001
Feasibility and low toxicity of early radiotherapy after high-dose chemotherapy and autologous stem cell transplantation for patients with high-risk stage II-III and locally advanced breast carcinoma.
    Cancer, 2001, Jun-01, Volume: 91, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinom

2001
[Prevention of postoperative recurrence of bladder cancer: a clinical study].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1999, Volume: 37, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; BCG

1999
Adjuvant therapy of T1 bladder carcinoma: preliminary results of an EORTC randomized study.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Pathology; Podophyllotoxin; Random Allocation;

1978
The role of intravesical thiotepa in the management of superficial bladder cancer. National Bladder Cancer Collaborative Group A.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Clinical Trials as Topic; Humans; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Postopera

1977
Comparisons of placebo, pyridoxine, and topical thiotepa in preventing recurrence of stage I bladder cancer.
    Urology, 1977, Volume: 10, Issue:6

    Topics: Administration, Oral; Administration, Topical; Clinical Trials as Topic; Drug Evaluation; Follow-Up

1977
Single dose intravesical thiotepa as an adjuvant to cystodiathermy in the treatment of transitional cell bladder carcinoma.
    British journal of urology, 1976, Volume: 48, Issue:1

    Topics: Carcinoma, Transitional Cell; Clinical Trials as Topic; Electrocoagulation; Female; Follow-Up Studie

1976
EORTC randomized trial for the adjuvant therapy of T1 bladder carcinoma.
    European urology, 1976, Volume: 2, Issue:6

    Topics: Carcinoma, Papillary; Clinical Trials as Topic; Follow-Up Studies; Humans; Neoplasm Recurrence, Loca

1976
[Neoadjuvant chemotherapy in combined treatment of breast cancer].
    Voprosy onkologii, 1992, Volume: 38, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyc

1992
A prospective randomized study of prophylaxis of tumor recurrence following transurethral resection of superficial bladder cancer--intravesical thio-TEPA versus oral UFT.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30 Suppl

    Topics: Administration, Intravesical; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Proto

1992
Randomized trial of adjuvant chemotherapy for operable breast cancer comparing i.v. CMF to an epirubicin-containing regimen [see comment].
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

1992
[BCG in superficial carcinoma of the bladder. Authors' experience].
    Actas urologicas espanolas, 1992, Volume: 16, Issue:6

    Topics: Administration, Topical; Adult; Aged; BCG Vaccine; Carcinoma in Situ; Drug Evaluation; Female; Human

1992
Adjuvant chemotherapy of recurrent superficial transitional cell carcinoma: results of a European organization for research on treatment of cancer randomized trial comparing intravesical instillation of thiotepa, doxorubicin and cisplatin. The European Or
    The Journal of urology, 1992, Volume: 148, Issue:2 Pt 1

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Transitiona

1992
Effects of primary chemotherapy in conservative treatment of breast cancer patients with operable tumors larger than 3 cm. Results of a randomized trial in a single centre.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Pro

1991
Bacillus Calmette-Guerin versus doxorubicin versus thiotepa: a randomized prospective study in 202 patients with superficial bladder cancer.
    The Journal of urology, 1990, Volume: 143, Issue:3

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; BCG Vaccine; Carcinoma, Transitional C

1990
Selective chemoprophylaxis guided by multifactorial analysis in superficial bladder cancer.
    European urology, 1990, Volume: 17, Issue:3

    Topics: Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin;

1990
Prognostic factors for recurrence and followup policies in the treatment of superficial bladder cancer: report from the British Medical Research Council Subgroup on Superficial Bladder Cancer (Urological Cancer Working Party).
    The Journal of urology, 1989, Volume: 142, Issue:2 Pt 1

    Topics: Administration, Intravesical; Carcinoma, Transitional Cell; Cystoscopy; Follow-Up Studies; Humans; M

1989
Intravesical therapy comparing BCG, adriamycin, and thiotepa in 200 patients with superficial bladder cancer: a randomized prospective study.
    Progress in clinical and biological research, 1989, Volume: 310

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; BCG Vaccine; Carcinoma, Transitional C

1989
BCG versus thiotepa in non-CIS, stage Ta, T1 bladder cancer: rationale and design of ECOG trial.
    Progress in clinical and biological research, 1989, Volume: 310

    Topics: Aged; BCG Vaccine; Carcinoma in Situ; Carcinoma, Transitional Cell; Doxorubicin; Female; Humans; Mal

1989
The effect of intravesical thiotepa on the recurrence rate of newly diagnosed superficial bladder cancer. An MRC Study. MRC Working Party on Urological Cancer.
    British journal of urology, 1985, Volume: 57, Issue:6

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Clinical Trials as Topic; Cystoscopy; Humans; Middle Aged

1985
A trial of prophylactic thiotepa or mitomycin C intravesical therapy in patients with recurrent or multiple superficial bladder cancers.
    The Journal of urology, 1986, Volume: 136, Issue:1

    Topics: Carcinoma, Transitional Cell; Clinical Trials as Topic; Humans; Mitomycin; Mitomycins; Neoplasm Recu

1986
Crossed chemoprophylaxis assay between adriamycin and cis-platinum in recurrent superficial bladder tumor.
    European urology, 1986, Volume: 12, Issue:4

    Topics: Cisplatin; Doxorubicin; Humans; Neoplasm Recurrence, Local; Random Allocation; Thiotepa; Urinary Bla

1986
Prophylactic treatment for superficial bladder cancer following transurethral resection.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20 Suppl

    Topics: Administration, Intravesical; Aged; Antineoplastic Agents; Carcinoma, Transitional Cell; Combined Mo

1987
[Evaluation of regimens for the simultaneous and sequential administration of cytostatics in the combined chemotherapy of disseminated forms of breast cancer].
    Voprosy onkologii, 1985, Volume: 31, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Fema

1985
Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group.
    Urology, 1985, Volume: 26, Issue:4 Suppl

    Topics: Administration, Topical; Biopsy; Carcinoma in Situ; Clinical Trials as Topic; Cystitis; Cystoscopy;

1985
Intravesical thiotepa and mitomycin C treatment immediately after transurethral resection and later for superficial (stages Ta and Tis) bladder cancer: a prospective, randomized, stratified study with crossover design.
    The Journal of urology, 1985, Volume: 134, Issue:6

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma in Situ; Carcinoma, Transitional Cell; Clinical

1985
Extended surgical adjuvant thiotepa for mammary carcinoma.
    Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 109, Issue:2

    Topics: Adenocarcinoma; Blood Cell Count; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Femal

1974
Controversies in the management of potentially curable breast cancer.
    Surgery annual, 1974, Volume: 6

    Topics: Breast Neoplasms; Castration; Clinical Trials as Topic; England; Female; Fluorouracil; Humans; Lymph

1974
Treatment of early breast cancer: a report after ten years of a clinical trial.
    British medical journal, 1972, May-20, Volume: 2, Issue:5811

    Topics: Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Lymphatic

1972
The use of triethylenethiophosphoramide as an adjuvant to the surgical treatment of colorectal carcinoma.
    Annals of surgery, 1967, Volume: 165, Issue:4

    Topics: Adult; Aged; Black or African American; Colonic Neoplasms; Ethnology; Female; Humans; Injections, In

1967
Chemotherapy in primary therapy of cancer of the breast.
    Cancer, 1967, Volume: 20, Issue:7

    Topics: Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mast

1967
Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation.
    Annals of surgery, 1968, Volume: 168, Issue:3

    Topics: Adult; Aged; Axilla; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouraci

1968
Complications and toxic manifestations of surgical adjuvant chemotherapy for breast cancer.
    Surgery, gynecology & obstetrics, 1968, Volume: 127, Issue:6

    Topics: Adult; Aged; Blood Cell Count; Blood Platelets; Blood Transfusion; Breast Neoplasms; Clinical Trials

1968
Extended surgical adjuvant chemotherapy for breast carcinoma.
    American journal of surgery, 1969, Volume: 117, Issue:5

    Topics: Adenocarcinoma; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Lymphatic Metastasis; Ma

1969
Postoperative radiotherapy in the treatment of breast cancer: results of the NSABP clinical trial.
    Annals of surgery, 1970, Volume: 172, Issue:4

    Topics: Adult; Age Factors; Breast Neoplasms; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Maste

1970
Results of a clinical trial concerning the worth of prophylactic oophorectomy for breast carcinoma.
    Surgery, gynecology & obstetrics, 1970, Volume: 131, Issue:6

    Topics: Adult; Breast Neoplasms; Castration; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Ma

1970

Other Studies

162 other studies available for thiotepa and Local Neoplasm Recurrence

ArticleYear
Intensive chemotherapy followed by autologous stem cell transplantation in primary central nervous system lymphomas (PCNSLs). Therapeutic outcomes in real life-experience of the French Network.
    Bone marrow transplantation, 2022, Volume: 57, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Central Nervous System; Centra

2022
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Effective T-cell replete haploidentical stem cell transplantation for pediatric patients with high-risk hematologic disorders.
    European journal of haematology, 2023, Volume: 110, Issue:3

    Topics: Busulfan; Child; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem

2023
Impact of Thiotepa-Based Autologous Hematopoietic Cell Transplantation in Primary Central Nervous System Lymphoma in First Complete Remission: A University of California Hematologic Malignancies Consortium Retrospective Analysis.
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:10

    Topics: Adult; Central Nervous System; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Human

2023
Impact of thiotepa dose-intensity in primary diffuse large B-cell lymphoma of the central nervous system undergoing autologous hematopoietic cell transplant with thiotepa/carmustine conditioning.
    Bone marrow transplantation, 2023, Volume: 58, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Autografts; Carmustine; Central Nervous Syste

2023
How I treat secondary CNS involvement by aggressive lymphomas.
    Blood, 2023, Nov-23, Volume: 142, Issue:21

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Humans; Lym

2023
Single-dose perioperative mitomycin-C versus thiotepa for low-grade noninvasive bladder cancer.
    The Canadian journal of urology, 2019, Volume: 26, Issue:5

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic A

2019
Thiotepa and antithymocyte globulin-based conditioning prior to haploidentical transplantation with posttransplant cyclophosphamide in high-risk hematological malignancies.
    Bone marrow transplantation, 2020, Volume: 55, Issue:4

    Topics: Antilymphocyte Serum; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic

2020
Tandem High-dose Chemotherapy without Craniospinal Irradiation in Treatment of Non-metastatic Malignant Brain Tumors in Very Young Children.
    Journal of Korean medical science, 2020, Dec-14, Volume: 35, Issue:48

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child, Preschool; Cran

2020
Outcomes Associated With Thiotepa-Based Conditioning in Patients With Primary Central Nervous System Lymphoma After Autologous Hematopoietic Cell Transplant.
    JAMA oncology, 2021, Jul-01, Volume: 7, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cohort Studies; Cyclop

2021
Intravenous busulfan-based conditioning with autologous stem cell transplantation for refractory B-cell lymphoma with central nervous system involvement.
    The journal of medical investigation : JMI, 2021, Volume: 68, Issue:1.2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System; Combi

2021
Frequency of Immune Cell Subtypes in Peripheral Blood Correlates With Outcome for Patients With Metastatic Breast Cancer Treated With High-Dose Chemotherapy.
    Clinical breast cancer, 2019, Volume: 19, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; CD8-Positive T

2019
Myeloablative chemotherapy and autologous stem cell transplantation in patients with relapsed or progressed central nervous system germ cell tumors: results of Korean Society of Pediatric Neuro-Oncology (KSPNO) S-053 study.
    Journal of neuro-oncology, 2013, Volume: 114, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous Syst

2013
Case-cohort analysis of clusters of recurrent events.
    Lifetime data analysis, 2014, Volume: 20, Issue:1

    Topics: Cluster Analysis; Cohort Studies; Computer Simulation; Humans; Likelihood Functions; Neoplasm Recurr

2014
Autologous stem cell transplant in recurrent or refractory primary or secondary central nervous system lymphoma using thiotepa, busulfan and cyclophosphamide.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neopla

2015
Whither thiotepa (for patients in the USA)?
    Journal of neuro-oncology, 2015, Volume: 124, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Female; Humans; Neoplasm Recurrence, Local; Ovarian Neoplasms; Th

2015
Efficacy and feasibility of autologous stem cell transplantation in patients with diffuse large B‑cell lymphoma with secondary central nervous system involvement.
    International journal of hematology, 2015, Volume: 102, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autografts; Busulfan; Central Nervous System Neoplas

2015
Intravesical chemotherapy use after radical nephroureterectomy: A national survey of urologic oncologists.
    Urologic oncology, 2017, Volume: 35, Issue:3

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Chem

2017
Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group.
    Pediatric blood & cancer, 2008, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Transpla

2008
No salvage using high-dose chemotherapy plus/minus reirradiation for relapsing previously irradiated medulloblastoma.
    International journal of radiation oncology, biology, physics, 2009, Apr-01, Volume: 73, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cerebellar Neoplasms; Child

2009
Outcome of patients with recurrent medulloblastoma or central nervous system germinoma treated with low dose continuous intravenous etoposide along with dose-intensive chemotherapy followed by autologous hematopoietic stem cell rescue.
    Pediatric blood & cancer, 2009, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nerv

2009
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome.
    Cancer, 2009, Jul-01, Volume: 115, Issue:13

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined

2009
Is radiotherapy an option for early breast cancers with complete clinical response after neoadjuvant chemotherapy?
    International journal of radiation oncology, biology, physics, 2011, Apr-01, Volume: 79, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dis

2011
Platine and cytarabine-based salvage treatment for primary central nervous system lymphoma.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combin

2011
[Sustained complete remission of intravascular large B-cell lymphoma with recurrent CNS involvement by autologous peripheral blood stem cell transplantation preconditioned with TBC regimen].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2011
Weighted logrank tests for interval censored data when assessment times depend on treatment.
    Statistics in medicine, 2012, Dec-10, Volume: 31, Issue:28

    Topics: Antineoplastic Agents, Alkylating; Bias; Biometry; Cluster Analysis; Computer Simulation; Data Inter

2012
Successful treatment of a recurrent choroid plexus carcinoma with surgery followed by high-dose chemotherapy and stem cell rescue.
    Pediatric hematology and oncology, 2013, Volume: 30, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carcinoma; Choroid Plexus Neoplasms; Combi

2013
[Triethylene-phosphoramide or thio-TEPA in therapy of recurrent cancer of the breast].
    La Presse medicale, 1959, Jan-24, Volume: 67, Issue:4

    Topics: Antineoplastic Agents; Breast; Breast Neoplasms; Humans; Neoplasm Recurrence, Local; Neoplasms; Phos

1959
ADJUVANT CHEMOTHERAPY (TRIETHYLENE THIOPHOSPHORAMIDE) WITH RADICAL MASTECTOMY AND RADIOTHERAPY IN BREAST CANCER.
    Canadian Medical Association journal, 1963, Dec-28, Volume: 89

    Topics: Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Humans; Leukopenia; Mastectomy; Mastectomy, Rad

1963
[PREVENTION OF THE RECURRENCE OF CANCER].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Animals; Biomedical Research; Genetic Diseases, X-Linked; Hormones; Leukemia, Hairy Cell; Lymphatic

1964
CYCLOPHOSPHAMIDE IN TREATMENT OF LOCALLY RECURRENT BREAST CANCER.
    Lancet (London, England), 1965, Jan-30, Volume: 1, Issue:7379

    Topics: Androgens; Breast; Breast Neoplasms; Cyclophosphamide; Drug Therapy; Estrogens; Humans; Hypophysecto

1965
DISSEMINATION OF CANCER WITH SPECIAL EMPHASIS ON VASCULAR SPREAD AND IMPLANTATION.
    Annals of surgery, 1965, Volume: 161

    Topics: Geriatrics; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplasms; Ne

1965
High-dose thiotepa and etoposide in children with poor-prognosis brain tumors.
    Cancer, 2004, May-15, Volume: 100, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplati

2004
Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-15, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dise

2004
Treatment of relapsed Wilms' tumor with high-dose therapy and autologous hematopoietic stem-cell rescue: the experience at Children's Memorial Hospital.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jul-15, Volume: 22, Issue:14

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cy

2004
High dose chemotherapy and autologous stem cell transplantation for poor risk and recurrent non-Hodgkin's lymphoma: a single-center experience of 50 patients.
    The Korean journal of internal medicine, 2004, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophos

2004
Multifocal motor neuropathy with conduction block associated with metastatic lymphoma of the nervous system.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Demyelinating Diseases; Female; He

2006
A case of relapsing glioblastoma multiforme responding to vinorelbine.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Combin

2006
[A case of recurrent breast cancer complicated with pericardial effusions and cardiac tamponade].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; B

2006
Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschoo

2007
Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain

2008
High-dose chemotherapy with autologous stem cell rescue followed by posterior fossa irradiation for local medulloblastoma recurrence or progression after conventional chemotherapy.
    Cancer, 2007, Jul-01, Volume: 110, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Busulfan; Cerebellar Neoplasms; Child

2007
[A case of recurrent renal cell carcinoma which recurred after fourth surgical resection and survived for about 2 years by medroxyporgesterone acetate administration].
    Hinyokika kiyo. Acta urologica Japonica, 2007, Volume: 53, Issue:9

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Ce

2007
Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant

2008
High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.
    Cancer, 2008, Apr-15, Volume: 112, Issue:8

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic;

2008
Minimal breast cancer. Clinical characteristics and treatment results.
    Neoplasma, 1983, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Breast Neoplasms; Carcinoma; Carcinoma in Situ; Female; H

1983
A comparison of treatment methods for the prophylaxis of recurrent superficial bladder tumors.
    The Journal of urology, 1983, Volume: 129, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; BCG Vaccine; Carcinoma, Transitional Cel

1983
Bladder cancer. Management of an increasingly common tumor.
    Postgraduate medicine, 1983, Volume: 73, Issue:3

    Topics: Endoscopy; Humans; Neoplasm Recurrence, Local; Thiotepa; Urinary Bladder Neoplasms

1983
[Use of thiotepa, in local instillation, as a prophylactic treatment for recurrence of superficial tumors of the bladder].
    Journal d'urologie, 1983, Volume: 89, Issue:2

    Topics: Administration, Topical; Adult; Aged; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Age

1983
Intravesical thiotepa prophylaxis of superficial bladder cancer. A follow-up study.
    European urology, 1983, Volume: 9, Issue:4

    Topics: Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Invasiv

1983
The influence of lower urinary tract infection on the recurrence rate of superficial transitional cell carcinoma of the bladder.
    The Journal of urology, 1983, Volume: 130, Issue:4

    Topics: Aged; Animals; Anti-Bacterial Agents; Carcinoma, Transitional Cell; Cystitis; Dogs; Female; Humans;

1983
Does intravesical chemotherapy prevent invasive bladder cancer?
    The Journal of urology, 1984, Volume: 131, Issue:1

    Topics: Administration, Topical; Aged; Antineoplastic Agents; Carcinoma, Transitional Cell; Follow-Up Studie

1984
Intrapelvic thiotepa for re-recurrence of transitional cell carcinoma of the renal pelvis in a solitary kidney.
    British journal of urology, 1984, Volume: 56, Issue:1

    Topics: Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Middle Aged; Neoplasm

1984
[The effect of various factors on the results of chemotherapy in patients with recurrent ovarian serous cystadenocarcinoma].
    Voprosy onkologii, 1984, Volume: 30, Issue:3

    Topics: Antineoplastic Agents; Combined Modality Therapy; Cyclophosphamide; Cystadenocarcinoma; Female; Huma

1984
Bilateral primary carcinoma of the ureter: topical intraureteral thiotepa.
    The Journal of urology, 1984, Volume: 132, Issue:2

    Topics: Administration, Topical; Carcinoma, Transitional Cell; Humans; Male; Middle Aged; Neoplasm Recurrenc

1984
Management of superficial bladder carcinoma with BCG. Long term follow-up.
    Progress in clinical and biological research, 1984, Volume: 162B

    Topics: BCG Vaccine; Combined Modality Therapy; Follow-Up Studies; Humans; Neoplasm Recurrence, Local; Thiot

1984
The value of thiotepa in the treatment of superficial bladder tumors.
    The Turkish journal of pediatrics, 1984, Volume: 26, Issue:1-4

    Topics: Adult; Aged; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neopla

1984
The effects of intravesical instillation of Thio-Tepa on the recurrence rate of bladder tumors.
    Acta medica Okayama, 1980, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Thiotepa

1980
Conservative management of low grade neoplasms of the male urethra: a preliminary report.
    The Journal of urology, 1980, Volume: 123, Issue:2

    Topics: Adult; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Fluorouracil; Humans; Male; Middle Ag

1980
The management of superficial bladder cancer.
    Cancer, 1980, Apr-15, Volume: 45, Issue:7 Suppl

    Topics: Adenocarcinoma; Carcinoma, Papillary; Carcinoma, Transitional Cell; Humans; Methods; Mitomycins; Neo

1980
[Use of a combination of pyrogenal and drug preparations in the overall treatment of breast cancer].
    Klinicheskaia khirurgiia, 1980, Issue:5

    Topics: Adult; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; M

1980
[The recurrence after conservative therapy of bladder cancer. II: The intravesical instillation of anti-cancer drug for preventing recurrence (author's transl)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1980, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Child; Female; Humans; Male; Midd

1980
The use of intravesical thio-tepa in the management of non-invasive carcinoma of the bladder.
    The Journal of urology, 1981, Volume: 125, Issue:3

    Topics: Humans; Neoplasm Recurrence, Local; Remission, Spontaneous; Thiotepa; Urinary Bladder; Urinary Bladd

1981
[Reoperation for severe hematuria following chemotherapy for bladder papillomatosis previously treated by surgery and cobalt therapy].
    Acta urologica Belgica, 1981, Volume: 49, Issue:1

    Topics: Administration, Topical; Aged; Hematuria; Humans; Male; Neoplasm Recurrence, Local; Papilloma; Thiot

1981
[Effect of cytostatics on tumor cells].
    Sovetskaia meditsina, 1980, Issue:12

    Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Mesothelioma;

1980
Intravesical thiotepa in prevention of recurrence of bladder tumour.
    Journal of the Indian Medical Association, 1980, Nov-01, Volume: 75, Issue:9

    Topics: Adult; Female; Humans; Male; Neoplasm Recurrence, Local; Thiotepa; Urinary Bladder; Urinary Bladder

1980
[Combination chemotherapy including anablastine in disseminated breast cancer].
    Voprosy onkologii, 1981, Volume: 27, Issue:5

    Topics: Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female;

1981
Use of intravesical thiotepa in superficial bladder tumours.
    Indian journal of cancer, 1981, Volume: 18, Issue:3

    Topics: Administration, Topical; Female; Follow-Up Studies; Humans; Male; Neoplasm Recurrence, Local; Neopla

1981
Early multiple-dose adjuvant thiotepa in the control of multiple and rapid T1 tumour neogenesis.
    British journal of urology, 1981, Volume: 53, Issue:6

    Topics: Drug Administration Schedule; Electrocoagulation; Female; Humans; Male; Middle Aged; Neoplasm Recurr

1981
[Chemotherapy associating mitomycin C, thiotepa and vindesine in advanced breast cancers. Study of 100 cases (author's transl)].
    Bulletin du cancer, 1981, Volume: 68, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Drug Therapy, Combination; Dru

1981
Intravitreal chemotherapy for recurrent retinoblastoma in an only eye.
    The British journal of ophthalmology, 1995, Volume: 79, Issue:2

    Topics: Combined Modality Therapy; Eye Neoplasms; Female; Humans; Infant; Male; Neoplasm Recurrence, Local;

1995
Regional chemotherapy for melanoma. A 35-year experience.
    Annals of surgery, 1994, Volume: 220, Issue:4

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials as Topic; Combined Modality T

1994
TMJ: a well-tolerated high-dose regimen for the adjuvant chemotherapy of high risk breast cancer.
    Journal of medicine, 1994, Volume: 25, Issue:3-4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms

1994
Rapid tumour recurrence following cessation of long-term treatment with intravesical thiotepa.
    British journal of urology, 1994, Volume: 74, Issue:1

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; BCG Vaccine; Carcinoma, Transitional Cell; Fe

1994
[Tumors of the superior urinary tract and associated bladder tumors: clinical and etiological aspects].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1993, Volume: 3, Issue:6

    Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Cystectomy; Female; Follow-Up Studies; Humans; I

1993
Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. The Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brai

1996
Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. The Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brai

1996
Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. The Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brai

1996
Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. The Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brai

1996
Double dose-intensive chemotherapy with autologous stem-cell support for metastatic breast cancer: no improvement in progression-free survival by the sequence of high-dose melphalan followed by cyclophosphamide, thiotepa, and carboplatin.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brea

1996
Pediatric leptomeningeal metastases: outcome following combined therapy.
    Journal of child neurology, 1997, Volume: 12, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Fluid; Chemotherapy, Cance

1997
Regional isolated perfusion of extremities for melanoma: a 20-year experience with drugs other than L-phenylalanine mustard.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carboplatin; Chemotherapy, Cancer, Regional P

1997
[High-dosage chemotherapy and autologous transplant of hematopoietic germ cells from peripheral blood in high-risk recurrence carcinoma of the breast (with >= or 10 involved axillary nodes at diagnosis) Preliminary results of the Solti 9301 cooperative st
    Sangre, 1997, Volume: 42 Suppl 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Carboplatin; Combin

1997
High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cerebellar Neoplasms

1998
[High-dose chemotherapy with four drugs and peripheral blood progenitor cell autologous transplantation in disseminated breast cancer].
    Medicina clinica, 1997, Dec-06, Volume: 109, Issue:20

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cyclophosphami

1997
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
    Neuro-oncology, 2000, Volume: 2, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta

2000
A general family of distributions for longitudinal dependence with special reference to event histories.
    Statistics in medicine, 2001, Jun-15, Volume: 20, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Granulomatous Disease, Chronic; Humans; Interferon-gamma; Longitu

2001
[Combination of high-dose chemotherapy with autologous hematopoietic stem cell transplantation for recurrent and high-risk breast cancer: a pilot study].
    Zhonghua yi xue za zhi, 1999, Volume: 79, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinoma, Duc

1999
High-dose adjuvant chemotherapy for patients with high-risk breast cancer: efficacy is still an open question.
    Clinical breast cancer, 2000, Volume: 1, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvan

2000
Intrathecal thiotepa: reappraisal of an established therapy.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Cerebrospinal Fluid; Child; Child, Preschool; Cohort

2002
Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescue.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:2

    Topics: Acyclovir; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Ph

2002
Intravesical thio-tepa in the immediate postoperative period in patients with recurrent transitional cell carcinoma of the bladder.
    The Journal of urology, 1978, Volume: 120, Issue:4

    Topics: Adolescent; Adult; Aged; Animals; Carcinoma, Transitional Cell; Child; Child, Preschool; Dogs; Follo

1978
Adjuvant chemotherapy or chemoimmunotherapy in the management of primary malignant melanoma of level III, IV, or V.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bacterial Vaccines; BCG Vaccine; Dacarbazine; Drug

1978
Local application of THIO-TEPA in the prevention of recurrent papillary carcinoma of the bladder.
    International urology and nephrology, 1979, Volume: 11, Issue:1

    Topics: Administration, Topical; Adult; Aged; Carcinoma, Papillary; Female; Humans; Male; Middle Aged; Neopl

1979
Intravesical chemotherapy and chemoprevention of superficial, low grade, low stage bladder carcinoma.
    Seminars in oncology, 1979, Volume: 6, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Humans; Neoplasm Recurrence, Local; Thiotepa; T

1979
[Chemotherapy of bladder neoplasms--studies of preventive measures against recurrence of superficial bladder neoplasms].
    Nihon rinsho. Japanese journal of clinical medicine, 1977, Volume: 35, Issue:5

    Topics: Carcinoma, Transitional Cell; Female; Humans; Male; Mitomycins; Neoplasm Recurrence, Local; Thiotepa

1977
[Endoscopic resection in the treatment of non-invasive excreto-urinary carcinomas of the bladder 146 endoscopic resections carried out in 53 patients].
    Journal d'urologie et de nephrologie, 1977, Volume: 83, Issue:6

    Topics: Adult; Aged; Animals; Carcinoma, Papillary; Endoscopy; Female; Humans; Male; Middle Aged; Neoplasm R

1977
Proceedings: Adjuvant intravesical thiotepa and bladder tumour recurrence.
    The British journal of surgery, 1975, Volume: 62, Issue:2

    Topics: Humans; Neoplasm Recurrence, Local; Neoplasm Seeding; Thiotepa; Urinary Bladder Neoplasms

1975
The prophylactic use of thio-tepa and urokinase in transitional cell carcinoma of the bladder: a preliminary report.
    The Journal of urology, 1975, Volume: 114, Issue:3

    Topics: Adolescent; Adult; Aged; Carcinoma, Transitional Cell; Cystitis; Drug Therapy, Combination; Endopept

1975
Survival after regional perfusion for limb melanoma.
    The Australian and New Zealand journal of surgery, 1975, Volume: 45, Issue:1

    Topics: Amputation, Surgical; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Humans; Lymphat

1975
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
[Intravesical BCG, mitomycin-C and thiotepa in the prevention of bladder tumor recurrence after operation].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1992, Volume: 30, Issue:7

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Chem

1992
Recurrence and treatment of urinary bladder cancer after failure in radiotherapy.
    Cancer, 1990, Dec-01, Volume: 66, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Doxorubicin; Female; Humans; Male; Middle

1990
[Superficial bladder cancer: prophylaxis of recurrence and progression].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:14

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Bleomycin; Cisplatin; Doxorubicin;

1991
Adjuvant therapy of stage II breast cancer treated with CMFVP, radiation therapy and VATH following lumpectomy. A pilot trial.
    American journal of clinical oncology, 1991, Volume: 14, Issue:4

    Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas

1991
High-dose thiotepa with autologous bone marrow rescue in recurrent malignant oligodendroglioma: a case report.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:1

    Topics: Bone Marrow Transplantation; Brain Neoplasms; Child; Combined Modality Therapy; Dose-Response Relati

1990
A phase II study of mitoxantrone, etoposide, and thiotepa with autologous marrow support for patients with relapsed breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brea

1990
Human plasma pharmacokinetics and urinary excretion of thiotepa and its metabolites.
    Cancer treatment reports, 1986, Volume: 70, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromatography, Gas;

1986
Combined intracavitary and external beam irradiation for superficial transitional cell carcinoma of the bladder: an alternative to cystectomy for patients with recurrence after intravesical chemotherapy.
    The Journal of urology, 1989, Volume: 141, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Transitional Cell; C

1989
Combination chemotherapy of advanced breast cancer. Comparison of dibromodulcitol, doxorubicin, vincristine, and fluoxymesterone to thiotepa, doxorubicin, vinblastine, and fluoxymesterone: an Eastern Cooperative Oncology Group Study.
    Cancer, 1989, Oct-01, Volume: 64, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

1989
Inhibition of implantation of murine bladder tumor by thiotepa in cauterized bladder.
    The Journal of urology, 1989, Volume: 142, Issue:6

    Topics: Administration, Intravesical; Animals; Carcinoma, Transitional Cell; Cautery; Disease Models, Animal

1989
Use of intravesical cisplatin and mitomycin-C for recurrent transitional cell carcinoma of bladder refractory to thiotepa.
    Urology, 1986, Volume: 27, Issue:4

    Topics: Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; Cisplatin; Cystoscopy; Drug Evaluation; Dru

1986
[Chemoprophylaxis with intravesical thiotepa in non-infiltrating bladder tumors].
    Archivos espanoles de urologia, 1986, Volume: 39, Issue:7

    Topics: Administration, Intravesical; Adult; Aged; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, L

1986
[Intravesical application of thio-tepa for preventing postoperative recurrence of bladder carcinoma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1986, Volume: 24, Issue:8

    Topics: Administration, Intravesical; Carcinoma, Squamous Cell; Humans; Neoplasm Recurrence, Local; Postoper

1986
Distilled water versus chemotherapeutic agents for transitional bladder carcinoma.
    European urology, 1986, Volume: 12, Issue:6

    Topics: Carcinoma, Transitional Cell; Cell Survival; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Neo

1986
[Vesicorenal reflux following endoscopic treatment of vesical tumors. Developmental and therapeutic complications].
    Journal d'urologie, 1986, Volume: 92, Issue:9

    Topics: Aged; Carcinoma, Papillary; Cystoscopy; Humans; Kidney Diseases; Male; Middle Aged; Neoplasm Recurre

1986
[Prognostic factors and risk of recurrence in a series of 385 patients with superficial bladder carcinoma treated with thiotepa, adriamycin or cisplatin].
    Archivos espanoles de urologia, 1987, Volume: 40, Issue:3

    Topics: Antineoplastic Agents; Cisplatin; Doxorubicin; Female; Humans; Male; Neoplasm Recurrence, Local; Pro

1987
Bladder wall calcification after topical mitomycin C.
    The Journal of urology, 1987, Volume: 138, Issue:5

    Topics: Administration, Intravesical; Aged; Calcinosis; Carcinoma, Transitional Cell; Combined Modality Ther

1987
[Preventive value of intravesical thiotepa on the recurrence of Ta-T1 vesical tumors treated by conservative surgery. Apropos of 247 cases a mean follow-up of 88 months].
    Journal d'urologie, 1987, Volume: 93, Issue:4

    Topics: Administration, Intravesical; Combined Modality Therapy; Follow-Up Studies; Humans; Neoplasm Recurre

1987
Effects of local chemotherapy and immunotherapy on the recurrence and progression of superficial bladder cancer.
    European urology, 1988, Volume: 14, Issue:5

    Topics: Administration, Intravesical; BCG Vaccine; Carcinoma, Transitional Cell; Combined Modality Therapy;

1988
Extensive distal subcutaneous metastases of a "benign" giant cell tumor of the radius.
    Plastic and reconstructive surgery, 1985, Volume: 75, Issue:2

    Topics: Adult; Bone Neoplasms; Doxorubicin; Female; Giant Cell Tumors; Hand; Humans; Neoplasm Metastasis; Ne

1985
Thiotepa versus adriamycin versus cis-platinum in the intravesical prophylaxis of superficial bladder tumors.
    European urology, 1985, Volume: 11, Issue:2

    Topics: Cisplatin; Doxorubicin; Drug Evaluation; Humans; Neoplasm Recurrence, Local; Postoperative Care; Thi

1985
Management of superficial bladder cancer in a community setting.
    Urology, 1985, Volume: 26, Issue:4 Suppl

    Topics: Administration, Topical; Carcinoma in Situ; Carcinoma, Transitional Cell; Cost-Benefit Analysis; Geo

1985
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Volume: 18, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms

1973
[FSH and steroid hormone excretion in breast cancer during chemotherapy].
    Voprosy onkologii, 1972, Volume: 18, Issue:10

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast Neoplasms; Cyclophosphamide; Estrogens; Female; F

1972
Renal failure associated with the use of thio-tepa.
    The Journal of urology, 1973, Volume: 110, Issue:5

    Topics: Acute Kidney Injury; Aged; Autopsy; Carcinoma, Transitional Cell; Humans; Inflammation; Male; Neopla

1973
[The so-called benign tumors of the urinary tract].
    Helvetica chirurgica acta, 1973, Volume: 40, Issue:5

    Topics: Adult; Female; Hematuria; Humans; Kidney Neoplasms; Male; Neoplasm Recurrence, Local; Papilloma; Thi

1973
[Benign bladder papillomas, prognosis and treatment. Attempt at an anatomo-clinical correlation].
    Helvetica chirurgica acta, 1973, Volume: 40, Issue:5

    Topics: Aged; Female; Humans; Male; Neoplasm Recurrence, Local; Papilloma; Prognosis; Thiotepa; Urinary Blad

1973
Bladder hyperthermia in the treatment of vesical papillomatosis.
    International urology and nephrology, 1973, Volume: 5, Issue:1

    Topics: Bacitracin; Buffers; Drug Combinations; Follow-Up Studies; Hematuria; Hot Temperature; Humans; Leuko

1973
[Thio-tepa in the prevention of recurrences of papillary bladder tumors].
    Zeitschrift fur Urologie und Nephrologie, 1973, Volume: 66, Issue:8

    Topics: Aged; Blood Cell Count; Blood Platelets; Carcinoma, Papillary; Female; Follow-Up Studies; Humans; Le

1973
Chemoprophylaxis of bladder cancer recurrence: immunological aspects.
    Panminerva medica, 1974, Volume: 16, Issue:3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Humans; Immune Adherenc

1974
[Local chemotherapy in vesical neoplasms].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1974, Volume: 55, Issue:11

    Topics: Antineoplastic Agents; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Neoplasm Recurr

1974
[Repeat surgery for recurring thecoma of the ovary].
    Voprosy onkologii, 1967, Volume: 13, Issue:7

    Topics: Androgens; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Thecoma; Thio

1967
[On the prevention of postoperative recurrences in cancer of the ovaries].
    Voprosy onkologii, 1968, Volume: 14, Issue:2

    Topics: Adult; Cyclophosphamide; Cystadenoma; Dysgerminoma; Female; Granulosa Cell Tumor; Humans; Middle Age

1968
Cancer chemotherapy in urology.
    Urologia internationalis, 1971, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal

1971
[Results of a comparative study of the efficacy of treatment of early forms of breast neoplasms by different methods].
    Voprosy onkologii, 1973, Volume: 19, Issue:3

    Topics: Adenocarcinoma, Scirrhous; Breast Neoplasms; Female; Humans; Menopause; Middle Aged; Neoplasm Metast

1973
Clinical and experimental projects on chemotherapy of bladder tumours.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Mar-30, Volume: 48, Issue:15

    Topics: Absorption; Alkylating Agents; Animals; Antineoplastic Agents; Cricetinae; Dogs; Drug Therapy, Combi

1974
Thio-TEPA and supervoltage radiotherapy for carcinoma of the ovary.
    Cancer, 1972, Volume: 29, Issue:4

    Topics: Adenocarcinoma, Papillary; Carcinoma; Cystadenocarcinoma; Cystadenoma; Evaluation Studies as Topic;

1972
[Cytostatic prophylactic treatment of superficial bladder tumours].
    Der Urologe. Ausg. A, 1972, Volume: 11, Issue:2

    Topics: Adult; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Papilloma; Thiotepa; Time Factors; Uri

1972
Perfusion of melanoma. 105 isolated perfusions in 92 patients.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Humans; Melanoma; Melphalan; Neoplasm Recurr

1972
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens;

1972
Chemotherapy for recurrent carcinoma of the breast.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Adult; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Hepatic Artery; Humans; Injections,

1972
Hormones, chemotherapy, and the breast cancer patient.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Administration, Oral; Adrenalectomy; Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluoro

1972
Chemotherapy in superficial neoplasms of the bladder.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Jul-01, Volume: 46, Issue:27

    Topics: Acids; Carcinoma, Papillary; Humans; Neoplasm Recurrence, Local; Papilloma; Precancerous Conditions;

1972
Optimal intravesical dosage of thio-tepa in the prophylaxis of recurrent bladder papillomatosis.
    Scandinavian journal of urology and nephrology, 1972, Volume: 6, Issue:1

    Topics: Administration, Oral; Cystoscopy; Humans; Injections; Leukopenia; Neoplasm Recurrence, Local; Papill

1972
[Thio-tepa in recurring carcinomas of the cervix uteri. Results].
    Revue francaise de gynecologie et d'obstetrique, 1966, Volume: 61, Issue:4

    Topics: Female; Humans; Neoplasm Recurrence, Local; Thiotepa; Uterine Cervical Neoplasms

1966
Malignant melanoma in childhood.
    Surgery, 1966, Volume: 59, Issue:2

    Topics: Humans; Infant; Lymph Node Excision; Male; Melanoma; Neoplasm Metastasis; Neoplasm Recurrence, Local

1966
The prophylactic use of thio-TEPA in transitional cell carcinoma of the bladder.
    The Journal of urology, 1966, Volume: 96, Issue:6

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, L

1966
Cyclophosphamide. Evaluation in recurrent and progressive ovarian cancer.
    American journal of obstetrics and gynecology, 1967, Mar-01, Volume: 97, Issue:5

    Topics: Cyclophosphamide; Female; Fluorouracil; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ova

1967
Systemic chemotherapy for carcinoma of the cervix.
    American journal of obstetrics and gynecology, 1967, Mar-15, Volume: 97, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Fema

1967
Severe pancytopenia associated with the use of intravesical thio-TEPA.
    The Journal of urology, 1967, Volume: 98, Issue:4

    Topics: Aged; Anemia, Aplastic; Carcinoma, Transitional Cell; Humans; Leukocyte Count; Male; Neoplasm Recurr

1967
[New experience with cytostatics, especially their intra-arterial use in bladder tumors].
    Zeitschrift fur Urologie und Nephrologie, 1966, Volume: 59, Issue:2

    Topics: Antineoplastic Agents; Electrosurgery; Humans; Injections, Intra-Arterial; Neoplasm Recurrence, Loca

1966
[Follow-up therapy with cytostatic drugs following surgery].
    Wiener klinische Wochenschrift, 1966, Jul-22, Volume: 78, Issue:29

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide; Female; Humans; Neoplas

1966
[Hormonal prevention of recurrence and metastasis in the complex treatment of breast cancer].
    Voprosy onkologii, 1968, Volume: 14, Issue:3

    Topics: Adult; Aged; Androgens; Breast Neoplasms; Castration; Estrogens; Female; Humans; Mastectomy; Middle

1968
The effects of topical THIOTEPA on the recurrence rate of superficial bladder cancers.
    The Journal of urology, 1968, Volume: 99, Issue:6

    Topics: Aged; Female; Humans; Male; Middle Aged; Mucous Membrane; Neoplasm Recurrence, Local; Thiotepa; Urin

1968
Thiotepa bladder instillations: therapy and prophylaxis for superficial bladder tumors.
    The Journal of urology, 1969, Volume: 101, Issue:5

    Topics: Blood Platelet Disorders; Cystitis; Cystoscopy; Humans; Leukopenia; Neoplasm Recurrence, Local; Solu

1969
The treatment of primary breast cancer. Comments.
    Archives of surgery (Chicago, Ill. : 1960), 1969, Volume: 99, Issue:3

    Topics: Adrenalectomy; Breast Neoplasms; Castration; Female; Humans; Hypophysectomy; Lymphatic Metastasis; N

1969
[Results of the surgical treatment of lung cancer].
    Voprosy onkologii, 1969, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Follow-Up Studies;

1969
[Surgical adjuvant chemotherapy of stomach cancer, with special reference to follow-up study of thio-TEPA and future problems].
    Gan no rinsho. Japan journal of cancer clinics, 1969, Volume: 15, Issue:5

    Topics: Female; Follow-Up Studies; Humans; Male; Mitomycins; Neoplasm Recurrence, Local; Sex Factors; Stomac

1969
Adjuvant chemotherapy in primary treatment of breast cancer.
    Radiology, 1969, Volume: 93, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Female; Humans; Mastectomy; Mechlorethami

1969
Therapeutic implications from a mathematical model characterizing the course of breast cancer.
    Cancer, 1969, Volume: 24, Issue:5

    Topics: Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Mastectomy;

1969
Prospects for the control of metastases.
    Cancer, 1969, Volume: 24, Issue:6

    Topics: Anticoagulants; Breast Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Neoplasm Recur

1969
Evaluation of adjunctive chemotherapy for recurrent cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 100, Issue:4

    Topics: Animals; Breast Neoplasms; Female; Fluorouracil; Humans; Mice; Neoplasm Recurrence, Local; Neoplasms

1970
Intracavitary chemotherapy for multiple non-invasive bladder tumours.
    British journal of urology, 1971, Volume: 43, Issue:2

    Topics: Alkylating Agents; Carcinoma, Papillary; Humans; Leukopenia; Neoplasm Recurrence, Local; Thiotepa; U

1971
Intravesical thiotepa in the treatment of transitional cell bladder carcinoma.
    British journal of urology, 1971, Volume: 43, Issue:2

    Topics: Aged; Bone Marrow; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Neoplasm Recurre

1971
[Results of treatment of tonsillar tumors by olivomycin].
    Antibiotiki, 1969, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Chlorpromazine; Cyclophosp

1969