thiotepa has been researched along with Leucocythaemia in 53 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study reports the results of UD-CBT in 22 adults with hematologic malignancies following conditioning with thiotepa, busulfan, cyclophosphamide, and antithymocyte globulin in 21, with thiotepa, fludarabine, and antithymocyte globulin in 1, and graft-versus-host disease (GVHD) prophylaxis with cyclosporine and prednisone." | 5.09 | Standardized, unrelated donor cord blood transplantation in adults with hematologic malignancies. ( Andreu, R; Barragán, E; Benlloch, L; Bolufer, P; Cervera, J; de La Rubia, J; García, I; Jarque, I; Jiménez, C; Larrea, L; Martín, G; Martínez, J; Marty, ML; Mollá, S; Moscardó, F; Planelles, D; Plumé, G; Regadera, AI; Saavedra, S; Sanz, GF; Sanz, MA; Senent, L; Soler, MA; Solves, P, 2001) |
| " We determined the pharmacokinetics of thioTEPA and its metabolite TEPA during first-dose infusion of thioTEPA 150-250 mg/m2 given daily for 3 days in combination with busulfan and cyclophosphamide, and evaluated the results for correlations with toxicity and dosing strategies." | 2.68 | Dosing of thioTEPA for myeloablative therapy. ( Dimopoulos, M; Estrov, Z; Ippoliti, C; Madden, T; Przepiorka, D, 1995) |
| "Chlorambucil and melphalan were the most leukemogenic drugs, followed by thiotepa; cyclophosphamide and treosulfan were the weakest leukemogens, and the effect per gram was substantially lower at high doses than at lower doses." | 2.67 | Leukemia following chemotherapy for ovarian cancer. ( Bell, J; Clarke, EA; Day, NE; Høst, H; Kaldor, JM; Karjalainen, S; Mehnert, W; Pedersen, D; Pettersson, F; Prior, P, 1990) |
| "Leptomeningeal carcinomatosis is defined as malignant infiltration of the pia matter and arachnoid membrane." | 2.43 | Management of leptomeningeal malignancy. ( Pavlidis, N; Pentheroudakis, G, 2005) |
| "However, survivors of brain tumors and any survivor who received high-dose neurotoxic treatment reported the lowest rates of achieving milestones of psychosexual development, whereas sexual and relationship status satisfaction were found to be related to relationship status." | 1.46 | Psychosexual development and satisfaction in long-term survivors of childhood cancer: Neurotoxic treatment intensity as a risk indicator. ( Bajwa, RPS; Gerhardt, CA; Hagedoorn, M; Keim, MC; Lehmann, V; Olshefski, RS; Tuinman, MA; Winning, AM, 2017) |
| "Among the causes of IRM, bacterial infections and IFIs were more common in sCBT (15% vs." | 1.42 | Severe infections after single umbilical cord blood transplantation in adults with or without the co-infusion of CD34+ cells from a third-party donor: results of a multicenter study from the Grupo Español de Trasplante Hematopoyético (GETH). ( Barba, P; Bautista, G; Cabrera, JR; Duarte, R; Esquirol, A; Fores, R; García, I; García-Marco, JA; Heras, I; Marquez-Malaver, FJ; Martino, R; Parody, R; Regidor, C; Rovira, M; Saavedra, S; Sánchez-Ortega, I; Serrano, D; Sierra, J; Vazquez, L, 2015) |
| "9 X 10(-4)M, and remained as a level of 10(-6)M for 72 hours with a half-life of 10." | 1.27 | [Pharmacokinetics of intrathecal chemotherapy and clinical problems]. ( Fujimoto, T, 1984) |
| "Rheumatoid arthritis was the most common underlying disease, in addition to giant cell arteritis, polyarteritis nodosa, chronic glomerulonephritis, and scleroderma." | 1.26 | Acute nonlymphocytic leukemia in patients receiving chemotherapy for nonmalignant diseases. ( Bukowski, RM; Hoffman, GC; Savage, RA; Sebek, BA; Sheibani, K; Tubbs, RR, 1980) |
| "Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0." | 1.26 | Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977) |
| " Pharmacokinetic studies have shown that these compounds possess particular affinity towards tumor tissue." | 1.26 | Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs. ( Djachkovskaya, RF; Emanuel, NM; Konovalova, NP, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (64.15) | 18.7374 |
| 1990's | 10 (18.87) | 18.2507 |
| 2000's | 5 (9.43) | 29.6817 |
| 2010's | 3 (5.66) | 24.3611 |
| 2020's | 1 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Bonifazi, F | 1 |
| Pavoni, C | 1 |
| Peccatori, J | 1 |
| Giglio, F | 1 |
| Arpinati, M | 1 |
| Busca, A | 2 |
| Bernasconi, P | 1 |
| Grassi, A | 1 |
| Iori, AP | 1 |
| Patriarca, F | 1 |
| Brunello, L | 1 |
| Di Grazia, C | 1 |
| Carella, AM | 1 |
| Cilloni, D | 1 |
| Picardi, A | 1 |
| Proia, A | 1 |
| Santarone, S | 1 |
| Sorasio, R | 1 |
| Carluccio, P | 1 |
| Chiusolo, P | 1 |
| Cupri, A | 1 |
| Luppi, M | 1 |
| Nozzoli, C | 1 |
| Baronciani, D | 1 |
| Casini, M | 1 |
| Grillo, G | 1 |
| Musso, M | 1 |
| Onida, F | 1 |
| Palazzo, G | 1 |
| Parma, M | 1 |
| Tringali, S | 1 |
| Vacca, A | 1 |
| Vallisa, D | 1 |
| Sacchi, N | 1 |
| Oldani, E | 1 |
| Masciulli, A | 1 |
| Gheorghiu, A | 1 |
| Girmenia, C | 1 |
| Martino, M | 1 |
| Bruno, B | 2 |
| Rambaldi, A | 1 |
| Ciceri, F | 1 |
| Martino, R | 1 |
| Bautista, G | 1 |
| Parody, R | 1 |
| García, I | 2 |
| Esquirol, A | 1 |
| Rovira, M | 1 |
| Cabrera, JR | 1 |
| Regidor, C | 1 |
| Fores, R | 1 |
| García-Marco, JA | 1 |
| Serrano, D | 1 |
| Barba, P | 1 |
| Heras, I | 1 |
| Marquez-Malaver, FJ | 1 |
| Sánchez-Ortega, I | 1 |
| Duarte, R | 1 |
| Saavedra, S | 2 |
| Sierra, J | 1 |
| Vazquez, L | 1 |
| Spitzer, B | 1 |
| Perales, MA | 1 |
| Kernan, NA | 1 |
| Prockop, SE | 1 |
| Zabor, EC | 1 |
| Webb, N | 1 |
| Castro-Malaspina, H | 1 |
| Papadopoulos, EB | 1 |
| Young, JW | 1 |
| Scaradavou, A | 1 |
| Kobos, R | 1 |
| Giralt, SA | 1 |
| O'Reilly, RJ | 1 |
| Boulad, F | 1 |
| Lehmann, V | 1 |
| Tuinman, MA | 1 |
| Keim, MC | 1 |
| Winning, AM | 1 |
| Olshefski, RS | 1 |
| Bajwa, RPS | 1 |
| Hagedoorn, M | 1 |
| Gerhardt, CA | 1 |
| Boccadoro, M | 1 |
| Locatelli, F | 1 |
| Falda, M | 1 |
| SHAY, H | 4 |
| ZARAFONETIS, C | 1 |
| SMITH, N | 1 |
| WOLDOW, I | 1 |
| SUN, DC | 3 |
| GRUENSTEIN, M | 1 |
| ATWATER, J | 1 |
| ZARAFONETIS, CJ | 1 |
| MCKENZIE, D | 1 |
| BRODY, JI | 1 |
| KIMURA, K | 1 |
| KURITA, S | 1 |
| KATCHMAN, BJ | 1 |
| ZIPF, RE | 1 |
| MURPHY, JP | 1 |
| MATSUOKA, M | 1 |
| PRAETORIUS, E | 1 |
| ARIEL, IM | 1 |
| RESNICK, MI | 1 |
| GALEY, D | 1 |
| LOPESCARDOZO, E | 1 |
| CHORIN, VA | 1 |
| ROSSOLIMO, OK | 1 |
| GOLDBERG, LE | 1 |
| STANISLAVSKAYA, MS | 1 |
| BLUMBERG, NA | 1 |
| VERTOGRADOVA, TP | 1 |
| DOWD, JE | 1 |
| DIPAOLO, JA | 1 |
| WATNE, AL | 1 |
| GERICKE, D | 1 |
| RAVINA, A | 1 |
| BRIDGES, JB | 1 |
| BRIDGES, JM | 1 |
| EDELSTYN, GJ | 1 |
| LYONS, AR | 1 |
| Kolb, EA | 1 |
| Steinherz, PG | 1 |
| Pentheroudakis, G | 1 |
| Pavlidis, N | 1 |
| Bunin, N | 1 |
| Aplenc, R | 1 |
| Grupp, S | 1 |
| Pierson, G | 1 |
| Monos, D | 1 |
| Easton, DJ | 1 |
| Poon, MA | 1 |
| Fujimoto, T | 1 |
| Sheibani, K | 1 |
| Bukowski, RM | 1 |
| Tubbs, RR | 1 |
| Savage, RA | 1 |
| Sebek, BA | 1 |
| Hoffman, GC | 1 |
| Adamson, RH | 1 |
| Seiber, SM | 1 |
| Mena, H | 1 |
| Garcia, JH | 1 |
| Velandia, F | 1 |
| Przepiorka, D | 2 |
| Madden, T | 1 |
| Ippoliti, C | 2 |
| Estrov, Z | 1 |
| Dimopoulos, M | 1 |
| Giralt, S | 1 |
| van Beisen, K | 1 |
| Mehra, R | 1 |
| Deisseroth, AB | 1 |
| Andersson, B | 1 |
| Luna, M | 1 |
| Cork, A | 1 |
| Lee, M | 1 |
| Rosenfeld, CS | 1 |
| Bolwell, B | 1 |
| LeFever, A | 1 |
| Taylor, R | 1 |
| List, A | 1 |
| Fay, J | 1 |
| Collins, R | 1 |
| Andrews, F | 1 |
| Pallansch, P | 1 |
| Schuster, MW | 1 |
| Resta, D | 1 |
| Levitt, D | 1 |
| Nemunaitis, J | 1 |
| Bacigalupo, A | 1 |
| Van Lint, MT | 1 |
| Valbonesi, M | 1 |
| Lercari, G | 1 |
| Carlier, P | 1 |
| Lamparelli, T | 1 |
| Gualandi, F | 1 |
| Occhini, D | 1 |
| Bregante, S | 1 |
| Valeriani, A | 1 |
| Piaggio, G | 1 |
| Pitto, A | 1 |
| Benvenuto, F | 1 |
| Figari, O | 1 |
| De Stefano, G | 1 |
| Caimo, A | 1 |
| Sessarego, M | 1 |
| Rosales, F | 1 |
| Naparstek, E | 1 |
| Varadi, G | 1 |
| Or, R | 1 |
| Slavin, S | 1 |
| Nagler, A | 1 |
| Sanz, GF | 1 |
| Planelles, D | 1 |
| Senent, L | 1 |
| Cervera, J | 1 |
| Barragán, E | 1 |
| Jiménez, C | 1 |
| Larrea, L | 1 |
| Martín, G | 1 |
| Martínez, J | 1 |
| Jarque, I | 1 |
| Moscardó, F | 1 |
| Plumé, G | 1 |
| Andreu, R | 1 |
| Regadera, AI | 1 |
| Mollá, S | 1 |
| Solves, P | 1 |
| de La Rubia, J | 1 |
| Bolufer, P | 1 |
| Benlloch, L | 1 |
| Soler, MA | 1 |
| Marty, ML | 1 |
| Sanz, MA | 1 |
| Kölmel, HW | 1 |
| Reimer, RR | 1 |
| Hoover, R | 1 |
| Fraumeni, JF | 1 |
| Young, RC | 1 |
| Manevich, ZA | 1 |
| Preĭnberg, GA | 1 |
| Emanuel, NM | 2 |
| Konovalova, NP | 1 |
| Djachkovskaya, RF | 1 |
| Tricot, G | 1 |
| Blaney, SM | 1 |
| Balis, FM | 2 |
| Poplack, DG | 2 |
| Martelli, MF | 2 |
| Aversa, F | 1 |
| Kaldor, JM | 1 |
| Day, NE | 1 |
| Pettersson, F | 1 |
| Clarke, EA | 1 |
| Pedersen, D | 1 |
| Mehnert, W | 1 |
| Bell, J | 1 |
| Høst, H | 1 |
| Prior, P | 1 |
| Karjalainen, S | 1 |
| Terenzi, A | 1 |
| Lubin, I | 1 |
| Lapidot, T | 1 |
| Salomon, O | 1 |
| Faktorowich, Y | 1 |
| Rabi, I | 1 |
| Reisner, Y | 1 |
| Garfield, DH | 1 |
| Modest, EJ | 1 |
| Fickers, M | 1 |
| Speck, B | 1 |
| Ota, K | 1 |
| Solomon, RB | 1 |
| Firat, D | 1 |
8 reviews available for thiotepa and Leucocythaemia
| Article | Year |
|---|---|
Allogenic stem cell transplantation following non-myeloablative conditioning regimens as adoptive immunotherapy in patients with hematological malignancies.
Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow; Humans; Immunotherapy, Adoptive; Leukemia; | 2002 |
Management of leptomeningeal malignancy.
Topics: Adenocarcinoma; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Arac | 2005 |
Chemically induced leukemia in humans.
Topics: Benzene; Chlorambucil; Chloramphenicol; Cyclophosphamide; Humans; Leukemia; Melphalan; Phenylbutazon | 1981 |
[Intrathecal application of antineoplastic agents (author's transl)].
Topics: Aminopterin; Antineoplastic Agents; Asparaginase; Azaguanine; Brain Neoplasms; Cyclophosphamide; Cyt | 1978 |
Tris (1-aziridinyl)phosphine sulphide.
Topics: Animals; Carcinogens; Drosophila melanogaster; Drug Evaluation, Preclinical; Female; Genes, Lethal; | 1975 |
Graft versus host disease prophylaxis today.
Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide | 1991 |
Central nervous system pharmacology of antileukemic drugs.
Topics: Antineoplastic Agents; Central Nervous System; Child; Cytarabine; Humans; Leukemia; Mercaptopurine; | 1989 |
Multiple combination therapy in cancer chemotherapy in Japan.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug | 1969 |
10 trials available for thiotepa and Leucocythaemia
| Article | Year |
|---|---|
Myeloablative conditioning with thiotepa-busulfan-fludarabine does not improve the outcome of patients transplanted with active leukemia: final results of the GITMO prospective trial GANDALF-01.
Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Prospect | 2022 |
Second Allogeneic Stem Cell Transplantation for Acute Leukemia Using a Chemotherapy-Only Cytoreduction with Clofarabine, Melphalan, and Thiotepa.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Adult; Arabinonucleosides; Child; Child, Preschool; | 2016 |
A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pres | 2003 |
Unrelated donor or partially matched related donor peripheral stem cell transplant with CD34+ selection and CD3+ addback for pediatric patients with leukemias.
Topics: Adolescent; Adult; Antigens, CD34; CD3 Complex; Child; Child, Preschool; Chronic Disease; Cyclophosp | 2006 |
Dosing of thioTEPA for myeloablative therapy.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Transplantation; Fema | 1995 |
A phase I-II study of high-dose thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic marrow transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busu | 1994 |
Comparison of four cytokine regimens for mobilization of peripheral blood stem cells: IL-3 alone and combined with GM-CSF or G-CSF.
Topics: Adult; Bone Marrow; Breast Neoplasms; Busulfan; Carboplatin; Carmustine; Cyclophosphamide; Drug Admi | 1996 |
Thiotepa cyclophosphamide followed by granulocyte colony-stimulating factor mobilized allogeneic peripheral blood cells in adults with advanced leukemia.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone M | 1996 |
Standardized, unrelated donor cord blood transplantation in adults with hematologic malignancies.
Topics: Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Femal | 2001 |
Leukemia following chemotherapy for ovarian cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Case-Control Studie | 1990 |
35 other studies available for thiotepa and Leucocythaemia
| Article | Year |
|---|---|
Severe infections after single umbilical cord blood transplantation in adults with or without the co-infusion of CD34+ cells from a third-party donor: results of a multicenter study from the Grupo Español de Trasplante Hematopoyético (GETH).
Topics: Adolescent; Adult; Antigens, CD34; Bacterial Infections; Busulfan; Cohort Studies; Cord Blood Stem C | 2015 |
Psychosexual development and satisfaction in long-term survivors of childhood cancer: Neurotoxic treatment intensity as a risk indicator.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cranial Irradiation; Cytarabine | 2017 |
Treatment of leukemia with triethylene thiophosphoramide (thio-TEPA); preliminary results in experimental and clinical leukemia.
Topics: Blood; Leukemia; Mitosis; Poisons; Thiotepa | 1953 |
Effect of triethylene thiophosphoramide and 6-mercaptopurine in chronic myelogenous and in an acute leukemia in rats.
Topics: Animals; Leukemia; Leukemia, Experimental; Mercaptopurine; Phosphorus; Purines; Rats; Thiotepa | 1955 |
Triethylene thiophosphoramide in the treatment of chronic leukemia.
Topics: Chronic Disease; Leukemia; Phosphorus; Phosphorus, Dietary; Thiotepa | 1955 |
Experimental and clinical experience with thio-TEPA in leukemia and inoperable cancer.
Topics: Antineoplastic Agents; Leukemia; Neoplasms; Thiotepa | 1958 |
Synergistic toxicity of triethylene thiophosphoramide and folic acid in the IRC-741 leukemia.
Topics: Folic Acid; Leukemia; Leukemia, Experimental; Thiotepa | 1963 |
[CLASSIFICATION OF LEUKEMIA BY SENSITIVITY OF CELLS TO DRUGS].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Busulfan; Cl | 1963 |
THE EFFECT OF CHEMOTHERAPEUTIC AGENTS UPON THE METABOLISM OF INTACT HUMAN CANCER CELLS: AN IN VITRO TECHNIC FOR CELL SENSITIVITY.
Topics: Aminopterin; Antineoplastic Agents; Azaguanine; Carbohydrate Metabolism; In Vitro Techniques; Lactat | 1963 |
[IMPROVEMENT AND EXACERBATION IN LEUKEMIA].
Topics: Aminocaproates; Aminocaproic Acid; Anemia; Antineoplastic Agents; Blood Transfusion; Busulfan; Centr | 1963 |
[SURVIVAL TIME AND ABILITY TO WORK IN HEMOBLASTOSES TREATED BY CHEMOTHERAPY].
Topics: Antineoplastic Agents; Aziridines; Biomedical Research; Cyclophosphamide; Genetic Diseases, X-Linked | 1963 |
THE INTRALYMPHATIC ADMINISTRATION OF RADIOACTIVE ISOTOPES AND CANCER CHEMOTHERAPEUTIC DRUGS.
Topics: Abdominal Neoplasms; Angiography; Breast Neoplasms; Geriatrics; Gold; Humans; Injections; Iodine Iso | 1964 |
[CYTOSTATIC THERAPY].
Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambucil; Colchicine; Cyclophosphamide; Femal | 1964 |
EXPERIMENTAL STUDY OF OLIVOMYCIN, AN ANTITUMOUR ANTIBIOTIC.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Carcin | 1964 |
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neop | 1964 |
[EXPERIENCE WITH ETHYLENEIMINES].
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Leukemi | 1964 |
[THE PRACTITIONER AND ANTINEOPLASTIC CHEMOTHERAPY. RECENT DATA].
Topics: Antineoplastic Agents; Dactinomycin; Glioma; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Perfusion | 1965 |
FEOTAL LIVER SUSPENSIONS IN THE TREATMENT OF MARROW APLASIA.
Topics: Anemia; Anemia, Aplastic; Antineoplastic Agents; Bone Marrow; Bone Marrow Diseases; Fetus; Hemoglobi | 1965 |
Acute nonlymphocytic leukemia following bladder instillations with thiotepa.
Topics: Acute Disease; Aged; Humans; Leukemia; Male; Papilloma; Thiotepa; Time Factors; Urinary Bladder; Uri | 1983 |
[Pharmacokinetics of intrathecal chemotherapy and clinical problems].
Topics: Acute Disease; Blood-Brain Barrier; Cytarabine; Humans; Infusions, Parenteral; Injections, Spinal; K | 1984 |
Acute nonlymphocytic leukemia in patients receiving chemotherapy for nonmalignant diseases.
Topics: Arthritis, Rheumatoid; Chromosomes; Drug Therapy, Combination; Drug-Related Side Effects and Adverse | 1980 |
Central and peripheral myelinopathy associated with systemic neoplasia and chemotherapy.
Topics: Adult; Aged; Axons; Brain; Cytarabine; Cytoskeleton; Female; Humans; Injections, Spinal; Leukemia; M | 1981 |
The role of thiotepa in allogeneic stem cell transplantation in patients with leukemia.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Combined Mo | 1999 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; | 1977 |
[Use of thiophosphamide in the treatment of bovine leukemia].
Topics: Animals; Cattle; Cattle Diseases; Drug Evaluation; Female; Leukemia; Thiotepa | 1977 |
Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs.
Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinic | 1976 |
T-cell depletion in unrelated bone marrow transplantation.
Topics: Adult; Aged; Antilymphocyte Serum; Bone Marrow Purging; Bone Marrow Transplantation; Cell Separation | 1992 |
Pharmacologic approaches to the treatment of meningeal malignancy.
Topics: Adolescent; Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Blood-Brain Barrier; Child; Chi | 1991 |
Enhancement of T cell-depleted bone marrow allografts in mice by thiotepa.
Topics: Animals; Bone Marrow Transplantation; Busulfan; Chimera; Cyclophosphamide; Female; Leukemia; Lymphoc | 1990 |
Acute erythromegakaryocytic leukaemia after treatment with cytostatic agents.
Topics: Adenocarcinoma; Aged; Bone Marrow Diseases; Erythrocytes; Humans; Leukemia; Lung Neoplasms; Male; Me | 1970 |
Leukaemia and cytotoxic drugs.
Topics: Alkylating Agents; Female; Humans; Leukemia; Melphalan; Multiple Myeloma; Thiotepa | 1971 |
Formal discussion: future prospects in leukemia chemotherapy.
Topics: Animals; Dactinomycin; Floxuridine; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; N | 1965 |
Kinetics and the free-radical mechanisms of tumor growth.
Topics: Animals; Benzyl Compounds; Brain; DDT; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; | 1973 |
Thrombocythaemia. Familial occurrence and transition into blastic crisis.
Topics: Alkaline Phosphatase; Anemia, Aplastic; Blood Coagulation Tests; Bone Marrow Examination; Busulfan; | 1974 |
Acute leukemia, following treatment with irradiation and alkylating agent.
Topics: Adenocarcinoma; Humans; Leukemia; Leukemia, Radiation-Induced; Lung Neoplasms; Male; Middle Aged; Ra | 1971 |