thiotepa has been researched along with Eye Cancer, Retinoblastoma in 9 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melphalan was a key drug in all patients, and was administered in combination with other agents such as cisplatin, cyclophosphamide, carboplatin or thiotepa." | 1.33 | A multidisciplinary treatment strategy that includes high-dose chemotherapy for metastatic retinoblastoma without CNS involvement. ( Higa, T; Hosono, A; Kaneko, A; Kawamoto, H; Makimoto, A; Matsubara, H; Murayama, S; Ohira, M; Sakiyama, S; Sumi, M; Takaue, Y; Takayama, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaradat, I | 1 |
| Mubiden, R | 1 |
| Salem, A | 1 |
| Abdel-Rahman, F | 1 |
| Al-Ahmad, I | 1 |
| Almousa, A | 1 |
| Kaneko, A | 2 |
| Suzuki, S | 1 |
| Matsubara, H | 1 |
| Makimoto, A | 1 |
| Higa, T | 1 |
| Kawamoto, H | 1 |
| Sakiyama, S | 1 |
| Hosono, A | 1 |
| Takayama, J | 1 |
| Takaue, Y | 1 |
| Murayama, S | 1 |
| Sumi, M | 1 |
| Ohira, M | 1 |
| Popovic, MB | 1 |
| Diezi, M | 1 |
| Kuchler, H | 1 |
| Abouzeid, H | 1 |
| Maeder, P | 1 |
| Balmer, A | 1 |
| Munier, FL | 1 |
| Seregard, S | 1 |
| Kock, E | 1 |
| af Trampe, E | 1 |
| Hertzberg, H | 1 |
| Kremens, B | 1 |
| Velten, I | 1 |
| Beck, JD | 1 |
| Greil, J | 1 |
| Heath, JA | 1 |
| Broxson, EH | 1 |
| Dole, MG | 1 |
| Filippa, DA | 1 |
| George, D | 1 |
| Lyden, D | 1 |
| Dunkel, IJ | 1 |
| Mahaley, MS | 1 |
| Woodhall, B | 1 |
| Iguchi, K | 1 |
| Ikeda, K | 1 |
| Nakamura, T | 1 |
| Toda, T | 1 |
| Akiyoshi, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open, Single-centre Non-randomized Phase II Clinical Trial on Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage[NCT01393769] | Phase 2 | 5 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to Only 5 subjects could be enrolled. Sample of 25 pat. not be achieved (rare disease).) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thiotepa and Eye Cancer, Retinoblastoma
| Article | Year |
|---|---|
High-dose chemotherapy followed by stem cell transplantation in the management of retinoblastoma: a systematic review.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Combined Modality Therapy; Humans; Retin | 2012 |
Eye-preservation treatment of retinoblastoma with vitreous seeding.
Topics: Animals; Antineoplastic Agents, Alkylating; Brachytherapy; Combined Modality Therapy; Humans; Inject | 2003 |
7 other studies available for thiotepa and Eye Cancer, Retinoblastoma
| Article | Year |
|---|---|
A multidisciplinary treatment strategy that includes high-dose chemotherapy for metastatic retinoblastoma without CNS involvement.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Carboplatin; Central Nervous Syst | 2005 |
Trilateral retinoblastoma with suprasellar tumor and associated pineal cyst.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Cysts; Child; Cy | 2007 |
Intravitreal chemotherapy for recurrent retinoblastoma in an only eye.
Topics: Combined Modality Therapy; Eye Neoplasms; Female; Humans; Infant; Male; Neoplasm Recurrence, Local; | 1995 |
Recurrent disseminated retinoblastoma in a 7-year-old girl treated successfully by high-dose chemotherapy and CD34-selected autologous peripheral blood stem cell transplantation.
Topics: Antigens, CD34; Antineoplastic Agents; Bone Marrow Neoplasms; Bone Neoplasms; Carboplatin; Child; Cy | 2001 |
Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescue.
Topics: Acyclovir; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Ph | 2002 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci | 1967 |
[Contineous intra-arterial perfusion of carcinostatic drugs for retinoblastoma].
Topics: Child, Preschool; Eye Neoplasms; Female; Humans; Infant; Injections, Intra-Arterial; Male; Methotrex | 1967 |