thiotepa has been researched along with Experimental Leukemia in 12 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SHAY, H | 2 |
| GRUENSTEIN, M | 2 |
| HARRIS, C | 1 |
| ATWATER, J | 1 |
| MCKENZIE, D | 1 |
| BRODY, JI | 1 |
| RUTMAN, RJ | 1 |
| Miller, B | 2 |
| Sosnovsky, G | 2 |
| Rao, NU | 2 |
| Gutierrez, PL | 2 |
| Tenenholz, T | 1 |
| Egorin, MJ | 1 |
| Prokhorova, EV | 1 |
| Konovalova, NP | 1 |
| D'iachkovskaia, RF | 1 |
| Kiseleva, EG | 1 |
| Wallace, JD | 1 |
| Merkulov, MF | 1 |
| Leskova, SG | 1 |
| Terent'eva, TG | 1 |
| Fomina, IP | 1 |
| Navashin, SM | 1 |
| Khomchenovskiĭ, EI | 1 |
1 review available for thiotepa and Experimental Leukemia
| Article | Year |
|---|---|
Free radicals and neoplasia--some experimental findings and some possible implications.
Topics: Adenofibroma; Animals; Breast Neoplasms; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Carcinoma | 1972 |
11 other studies available for thiotepa and Experimental Leukemia
| Article | Year |
|---|---|
The effect of triethylene thiophosphoramide (thio-TEPA) in the treatment of chronic myelocytic chloroleukemia in the rat.
Topics: Animals; Leukemia, Experimental; Phosphorus; Rats; Thiotepa | 1954 |
Effect of triethylene thiophosphoramide and 6-mercaptopurine in chronic myelogenous and in an acute leukemia in rats.
Topics: Animals; Leukemia; Leukemia, Experimental; Mercaptopurine; Phosphorus; Purines; Rats; Thiotepa | 1955 |
Synergistic toxicity of triethylene thiophosphoramide and folic acid in the IRC-741 leukemia.
Topics: Folic Acid; Leukemia; Leukemia, Experimental; Thiotepa | 1963 |
EXPERIMENTAL CHEMOTHERAPY STUDIES. V. THE COLLATERAL SENSITIVITY TO ALKYLATING AGENTS OF SEVERAL ANTIMETABOLITE-RESISTANT ASCITES TUMORS IN MICE.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Ascites; Azaserine; Carcinoma, E | 1964 |
In the search for new anticancer drugs. XX: A comparison of the in vitro growth inhibition of P388 cells by TEPA and N,N;N',N'-bis (1,2-ethanediyl)-N''-(1-oxyl-2,2,6,6-tetramethyl-4- piperidinylaminocarbonyl) phosphoric triamide and congeners.
Topics: Animals; Antineoplastic Agents; Azirines; Cell Line; Leukemia P388; Leukemia, Experimental; Structur | 1987 |
Cellular pharmacology of N,N',N''-triethylene thiophosphoramide.
Topics: Animals; Cell Division; Cell Survival; DNA Replication; DNA, Neoplasm; Kinetics; Leucine; Leukemia P | 1988 |
[Effectiveness in vivo of some antiblastomic preparations in relation to cells resistant to bruneomycin and olivomycin].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Culture Techniques; Cyclopho | 1969 |
[Toxicity and antineoplastic activity of a new thio-TEPA analog].
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Squa | 1973 |
[Use of transplantability indices of tumor cells for evaluation of the cytotoxic effect of antineoplastic agents in vitro].
Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Fluorouracil; Leukemia, Experimental; Male; Melp | 1972 |
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; As | 1970 |
[A comparative quantitative study of the anti-leukemia activity of hexaphosphamide, various anti-leukemia preparations and x-rays].
Topics: Acute Disease; Animals; Antineoplastic Agents; Leukemia, Erythroblastic, Acute; Leukemia, Experiment | 1968 |