Page last updated: 2024-11-05

thiotepa and ER-Negative PR-Negative HER2-Negative Breast Cancer

thiotepa has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 3 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
de Boo, L1
Cimino-Mathews, A1
Lubeck, Y1
Daletzakis, A1
Opdam, M1
Sanders, J1
Hooijberg, E1
van Rossum, A1
Loncova, Z1
Rieder, D1
Trajanoski, Z1
Vollebergh, M1
Sobral-Leite, M1
van de Vijver, K1
Broeks, A1
van der Wiel, R1
van Tinteren, H2
Linn, S1
Horlings, HM1
Kok, M1
Vollebergh, MA1
Lips, EH1
Nederlof, PM1
Wessels, LF1
Wesseling, J1
Vd Vijver, MJ1
de Vries, EG1
Jonkers, J1
Hauptmann, M1
Rodenhuis, S1
Linn, SC1
Wang, X1
Ren, J1
Zhang, J1
Yan, Y1
Jiang, N1
Yu, J1
Di, L1
Song, G1
Che, L1
Jia, J1
Zhou, X1
Yang, H1
Lyerly, HK1

Trials

2 trials available for thiotepa and ER-Negative PR-Negative HER2-Negative Breast Cancer

ArticleYear
Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 127

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Prote

2020
Prospective study of cyclophosphamide, thiotepa, carboplatin combined with adoptive DC-CIK followed by metronomic cyclophosphamide therapy as salvage treatment for triple negative metastatic breast cancers patients (aged <45).
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2016, Volume: 18, Issue:1

    Topics: Administration, Metronomic; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chem

2016

Other Studies

1 other study available for thiotepa and ER-Negative PR-Negative HER2-Negative Breast Cancer

ArticleYear
Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy.
    Breast cancer research : BCR, 2014, May-15, Volume: 16, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Prote

2014