thiotepa has been researched along with EHS Tumor in 53 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was shown in rat experiments that high-altitude hypoxia inhibits the growth of transplantable tumors and enhances the efficacy of antitumor treatment with chemotherapeutic drugs (thiotepa for Heren's carcinoma, and cyclophosphamide for sarcoma 45)." | 3.66 | [Effect of high-altitude hypoxia on the effectiveness of chemotherapy in tumors]. ( Galkina, KA; Kulish, OP, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHERNOV, VA | 4 |
| PRESNOVA, Zh | 2 |
| STEVENS, DA | 1 |
| EASTY, GC | 1 |
| AMBROSE, EJ | 1 |
| PRADHAN, SN | 1 |
| WEST, WL | 1 |
| HILLER, SA | 1 |
| LIDAKS, MJ | 1 |
| ZIDERMANE, AA | 1 |
| GERMANE, SK | 1 |
| GRIGALINOVICH, GA | 1 |
| DAUVARTS, AZ | 1 |
| KRAVCHENKO, IM | 1 |
| PRESS, BO | 1 |
| HANDLER, AH | 1 |
| SARRIS, TG | 1 |
| WILLS, C | 1 |
| GRUSHINA, AA | 2 |
| SORKINA, YA | 1 |
| VERMEL, EM | 1 |
| TSETLIN, AL | 1 |
| SAKURAI, Y | 1 |
| GREKH, IF | 1 |
| KARLINSKAIA, RS | 1 |
| TURBINA, IL | 1 |
| SUKHIN, GM | 2 |
| PEREVOSHCHIKOVA, KA | 1 |
| BESLEKOEV, TI | 1 |
| SURODEIKINA, LN | 1 |
| GARIBDZHANIAN, BT | 1 |
| Kulish, OP | 1 |
| Galkina, KA | 1 |
| Garkavi, LKh | 1 |
| Kvakina, EB | 1 |
| Mulatova, AK | 1 |
| Taras'iants, FM | 1 |
| Kavetskiĭ, RE | 1 |
| Balitskiĭ, KP | 1 |
| Veksler, IG | 2 |
| Vetrova, EP | 1 |
| Vorontsova, AL | 1 |
| Peliukova, RN | 1 |
| Bulbuk, GA | 1 |
| Modest, EJ | 1 |
| Stenram, U | 2 |
| Nilsson, E | 2 |
| Berg, R | 2 |
| Moskalik, KG | 1 |
| Kozlov, AP | 1 |
| Akimov, AA | 1 |
| Konovalova, NP | 1 |
| D'iachkovskaia, RF | 1 |
| Kiseleva, EG | 1 |
| Yron, I | 1 |
| Weiss, DW | 1 |
| Robinson, E | 1 |
| Cohen, D | 1 |
| Adelberg, MG | 1 |
| Mekori, T | 1 |
| Haber, M | 1 |
| Merkulov, MF | 2 |
| Leskova, SG | 2 |
| Woenckhaus, HJ | 1 |
| Klemm, D | 1 |
| Obrecht, P | 1 |
| Barton, AA | 1 |
| Barton, M | 1 |
| Tsyrlina, EV | 1 |
| Kochetkova, VA | 1 |
| Morozov, AP | 1 |
| Bulkina, ZP | 1 |
| Poliak, NR | 1 |
| Miuller, NR | 2 |
| Anisimov, VN | 1 |
| Ershova, IuA | 1 |
| Bass-Shadkhan, KhF | 4 |
| Zakenfel'd, GK | 1 |
| Liepa, VE | 2 |
| Birzgale, VP | 1 |
| Prane, LIu | 1 |
| Mergina, GR | 1 |
| Hoshi, A | 1 |
| Kumagai, K | 1 |
| Kanzawa, F | 1 |
| Kuretani, K | 1 |
| Sorkina, IuA | 1 |
| Presnova, ZhF | 1 |
| Kulik, GI | 2 |
| Pel'kis, FP | 1 |
| Arkhangel'skaia, AV | 1 |
| Maliugina, LL | 1 |
| Pol'kina, RI | 1 |
| Remizov, AL | 1 |
| Petrov, AS | 1 |
| Kraĭz, BO | 1 |
| Lazarev, NV | 1 |
| Shelaputina, ZF | 1 |
| Iavorskaia, NP | 2 |
| Mashburn, LT | 1 |
| Schmähl, D | 1 |
2 reviews available for thiotepa and EHS Tumor
| Article | Year |
|---|---|
[Use of optical quantum generators (lasers) in oncology].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Basal Cell; Carcinom | 1972 |
[Side-effects of cytostatic therapy with special reference to potential carcinogenic effects].
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bus | 1971 |
51 other studies available for thiotepa and EHS Tumor
| Article | Year |
|---|---|
[CHANGES IN DEPOLYMERASE ACTIVITY OF NUCLEIC ACIDS IN RATS WITH TRANSPLANTABLE TUMORS UNDER THE INFLUENCE OF ETHYLENIMINE DERIVATIVES].
Topics: Antineoplastic Agents; Aziridines; Clinical Enzyme Tests; Deoxyribonucleases; DNA; Neoplasm Transpla | 1963 |
THE ASSAY OF THE EFFECT OF CHEMICAL AGENTS ON TUMOUR INVASION USING CHICK EMBRYOS.
Topics: Animals; Astrocytoma; Biological Assay; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chick Embry | 1963 |
FURTHER STUDIES ON THE EFFECT OF THIOTEPA ON THE SYNTHESIS OF PROTEIN AND NUCLEIC ACIDS IN TUMOR-BEARING MICE.
Topics: Animals; DNA; DNA, Neoplasm; Glycine; Lymphoma, Non-Hodgkin; Metabolism; Mice; Neoplasm Proteins; Ne | 1964 |
ANTITUMOROUS SUBSTANCES WITH RADIOMIMETIC AND RADIOPROTECTIVE GROUPS.
Topics: Acetylcholine; Antineoplastic Agents; Blood Pressure; Carcinoma 256, Walker; Cats; Erythropoiesis; L | 1964 |
CHEMOTHERAPY STUDIES ON PRIMARY TUMOR GRAFTS AND METASTASES IN HAMSTERS AND MICE.
Topics: Antineoplastic Agents; Cricetinae; Cyclophosphamide; Dactinomycin; Melphalan; Mice; Mitomycin; Mitom | 1964 |
THE EFFECT PRODUCED BY SOME HORMONES ON THE ANTITUMOUR ACTIVITY OF ETHYLENIMINE AND BETA-CHLORETHYLAMINE DERIVATIVES.
Topics: Adrenocorticotropic Hormone; Antineoplastic Agents; Aziridines; Cortisone; Growth Hormone; Neoplasms | 1964 |
[ON THE ANTINEOPLASTIC ACTIVITY OF SOME FUROCOUMARINS].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Furans; Furocoumarins; Khellin; | 1964 |
IN VITRO CULTURE OF YOSHIDA SARCOMA CELLS: METHODS FOR DETERMINING ACQUIRED RESISTANCE TO DRUGS.
Topics: Animals; Antineoplastic Agents; Azaguanine; Culture Media; Cyclophosphamide; Dactinomycin; Drug Tole | 1964 |
[RESULTS OF THE TREATMENT OF RATS WITH TRANSPLANTED SARCOMA SSK WITH THIOTEPA ASSOCIATED WITH SOME PYRIMIDINE DERIVATIVES].
Topics: Antineoplastic Agents; Neoplasm Transplantation; Neoplasms; Pharmacology; Pyrimidines; Research; Sar | 1964 |
[BONE MARROW TRANSPLANTATION IN RATS WITH M-1 SARCOMA AFTER ADMINISTRATION OF TOXIC DOSES OF THIO-TEPA].
Topics: Animals; Bone Marrow Transplantation; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Exp | 1965 |
THE ACTION OF SOME METABOLIC INHIBITORS UPON THE ACCUMULATION OF AMINO ACIDS AND THE INCORPORATION OF THE LATTER INTO THE PROTEINS OF THE TUMOR CELLS IN VITRO.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Glyc | 1964 |
[EFFECT OF BONE MARROW TRANSPLANTATION IN THE TREATMENT OF SARCOMA-M-1 IN RATS WITH THIO-TEPA].
Topics: Animals; Bone Marrow Transplantation; Neoplasms; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1965 |
[CHANGES IN THE ANTITUMOR ACTIVITY OF THIOPHOSPHAMIDE WITH ADRENALIN UNDER EXPERIMENTAL CONDITIONS].
Topics: Animals; Epinephrine; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiot | 1964 |
[EFFECT OF THIO-TEPA ON THE BLOOD PROTEIN COMPOSITION IN SARCOMA M-1].
Topics: Blood Proteins; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1964 |
[EFFECT OF THIO-TEPA ON THE PHAGOCYTIC ACTIVITY OF LEUKOCYTES (EXPERIMENTAL STUDY)].
Topics: Animals; Leukocytes; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1964 |
[Effect of high-altitude hypoxia on the effectiveness of chemotherapy in tumors].
Topics: Altitude Sickness; Animals; Carcinoma; Cyclophosphamide; Drug Evaluation, Preclinical; Female; Hypox | 1983 |
[Experimental use of antitumor preparations in low doses].
Topics: Adaptation, Physiological; Animals; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Resista | 1981 |
[Tilorone, a synthetic immunostimulator possessing antitumor activity].
Topics: Animals; Antibody-Producing Cells; Antineoplastic Agents; Drug Evaluation, Preclinical; Fluorenes; I | 1977 |
[Effect of thiophosphamide on carcinomia in rats with sarcoma SSK].
Topics: Animals; Female; Neoplastic Cells, Circulating; Rats; Sarcoma, Experimental; Thiotepa | 1976 |
[The effect of extirpation of the adrenals on changes in the perimural hydrolysis of carbohydrates in animals with sarcoma 45 and receiving thiophosphamide and 5-fluorouracil].
Topics: Adrenal Glands; Adrenalectomy; Amylases; Animals; Diet; Female; Fluorouracil; Intestinal Mucosa; Int | 1973 |
Formal discussion: future prospects in leukemia chemotherapy.
Topics: Animals; Dactinomycin; Floxuridine; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; N | 1965 |
The effect of some cancer-therapeutic agents on the transplantability and growth of an SV40 sarcoma in rat.
Topics: Animals; Cyclophosphamide; Neoplasm Transplantation; Rats; Sarcoma, Experimental; Simian virus 40; T | 1968 |
Effects of some cancer-chemotherapeutic agents, especially cyclophosphamide, on an SV40 sarcoma in rat.
Topics: Animals; Azathioprine; Cyclophosphamide; Fluorouracil; Hydrocortisone; Neoplasm Transplantation; Rat | 1969 |
[Toxicity and antineoplastic activity of a new thio-TEPA analog].
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Squa | 1973 |
Immunotherapeutic studies in mice with the methanol-extraction residue (mer) fraction of BCG: solid tumors.
Topics: Animals; Antigens, Bacterial; BCG Vaccine; Benzopyrenes; Cyclophosphamide; Female; Fibrosarcoma; Flu | 1973 |
[Use of transplantability indices of tumor cells for evaluation of the cytotoxic effect of antineoplastic agents in vitro].
Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Fluorouracil; Leukemia, Experimental; Male; Melp | 1972 |
[Studies on the lengthening of the survival time of RF mice with retothelial sarcoma by the combination of radiotherapy and chemotherapy].
Topics: Animals; Antineoplastic Agents; Azirines; Lymphoma, Large B-Cell, Diffuse; Mice; Radiation Effects; | 1965 |
Electron microscope studies on the effect of thiotepa on the cytoplasm of fibrosarcoma cells grown in tissue culture.
Topics: Animals; Culture Techniques; Cytoplasm; Fibrosarcoma; Mice; Microscopy, Electron; Sarcoma, Experimen | 1965 |
[Influence of chemotherapeutic agents combined with the extract of eleutherococcus senticosus on rise and development of the "SSK" tumour metastases].
Topics: Animals; Antineoplastic Agents; Drug Synergism; Melphalan; Mice; Neoplasm Metastasis; Plants, Medici | 1965 |
An experimental comparative study of the distribution of P32-labelled Thio-Tepa and P32 tag.
Topics: Animals; Phosphorus Isotopes; Rats; Sarcoma, Experimental; Thiotepa | 1967 |
[Effect of prodigiozan on the therapeutic effect and toxicity of some antitumor preparations].
Topics: Adrenal Glands; Animals; Antineoplastic Agents; Body Weight; Drug Synergism; Leukocytes; Liver; Melp | 1968 |
[Vitamin B-12 in the chemotherapy of experimental tumors].
Topics: Animals; Mice; Nitrogen Mustard Compounds; Rats; Sarcoma, Experimental; Thiotepa; Vitamin B 12 | 1968 |
[A study of the combined effect of antitumorous alkylating agents and vitamin B 12 on a model of a metastasizing tumor].
Topics: Animals; Lung Neoplasms; Lymphatic Metastasis; Melphalan; Neoplasm Metastasis; Neoplasm Transplantat | 1966 |
[On the anti-tumor action of N,N'-malonyl-bis-ethyleneimine].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Injections, Intraperitoneal; Mice; Rats; S | 1967 |
[Effect of thiophosphamide and DEPA on the mitotic activity of tumorous and normal tissue of rats with sarcoma 45].
Topics: Animals; Bone Marrow; Heart; Male; Mitosis; Rats; Sarcoma, Experimental; Thiotepa | 1968 |
[Serum protein fractions of sarcomatous mice subjected to the combined effect of zymosan and thio-TEPA].
Topics: Animals; Blood Proteins; Male; Rats; Sarcoma, Experimental; Thiotepa; Zymosan | 1968 |
[Levels of properdin in the serum of rats submitted to the combined effect of zymosan and thio-TEPA].
Topics: Animals; Neoplasm Transplantation; Properdin; Rats; Sarcoma, Experimental; Thiotepa; Transplantation | 1968 |
[Various biologic indices in sarcomatous rats administered thio-TEPA together with zymosan].
Topics: Animals; Male; Rats; Sarcoma, Experimental; Thiotepa; Zymosan | 1968 |
[Study of the hemo-stimulating effect of zymosan according to findings in the blood and bone marrow of normal subjects and experimental animals with tumors during their treatment with thio-TEPA].
Topics: Animals; Bone Marrow; Male; Rabbits; Rats; Sarcoma, Experimental; Thiotepa; Zymosan | 1968 |
[Aminotransferase activity in the liver, blood plasma and tumors of mice with sarcoma M-1 under the influence of thio-TEPA and zymosan].
Topics: Animals; Liver; Male; Rats; Sarcoma, Experimental; Thiotepa; Transaminases; Zymosan | 1968 |
[Comparative evaluation of the effect of ionizing radiation, thio-TEPA and their combined use on various indices of the blood of mice diseased with sarcoma M-1].
Topics: Animals; Blood Proteins; Male; Rats; Sarcoma, Experimental; Thiotepa | 1968 |
Sensitivity of Nakahara-Fukuoka sarcoma to antitumor agents, especially to purine analogs.
Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Fluorouracil; Hydrocortisone; Me | 1969 |
[The influence of desoxycorticosterone on the anti-tumor effect of thiophosphamide in intact and adrenalectomized rats with sarcoma 45].
Topics: Adrenal Glands; Animals; Desoxycorticosterone; Male; Rats; Sarcoma; Sarcoma, Experimental; Thiotepa | 1969 |
[The effect of antineoplastic alkylating agents on the serum protein fraction of rats with sarcoma 45].
Topics: Alkylating Agents; Animals; Blood Protein Disorders; Blood Protein Electrophoresis; Cyclophosphamide | 1969 |
[Dynamics of the cerebral ammonia-glutamine system in rat tumor carriers following surgical and chemotherapeutic removal of the tumor].
Topics: Ammonia; Animals; Brain Chemistry; Glutamates; Glutamine; Male; Rats; Sarcoma, Experimental; Thiotep | 1969 |
[Experimental basis for methods of determining individual sensitivity of tumors to alkylating antitumor preparations].
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cyclophosphamide; Male; Melphalan; Neoplasms, Exp | 1969 |
[The anti-tumor effect of several mono- and di-chlor-sym.triazine derivatives].
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Female; Leukopenia; Lung Neoplasms; Lympho | 1970 |
[Resistance of malignant tumors to chemotherapeutic effects].
Topics: Animals; Lymphoma, Non-Hodgkin; Male; Rats; Sarcoma, Experimental; Thiotepa | 1970 |
[Effect of thiophosphamide on the incorporation of H3-thymidine into the DNA of cells of surviving transplantable tumor sections sensitive and resistant toward the agent].
Topics: Animals; Body Weight; Depression, Chemical; DNA, Neoplasm; In Vitro Techniques; Male; Mice; Rats; Sa | 1971 |
Combination chemotherapy with L-asparaginase (EC-2) using P1798 lymphosarcoma.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cyclophosphami | 1971 |
[Probit-analysis in the evaluation of the selectivity of antineoplastic effect of agents].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Evaluation Studies as Topic | 1971 |