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thiotepa and EHS Tumor

thiotepa has been researched along with EHS Tumor in 53 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"It was shown in rat experiments that high-altitude hypoxia inhibits the growth of transplantable tumors and enhances the efficacy of antitumor treatment with chemotherapeutic drugs (thiotepa for Heren's carcinoma, and cyclophosphamide for sarcoma 45)."3.66[Effect of high-altitude hypoxia on the effectiveness of chemotherapy in tumors]. ( Galkina, KA; Kulish, OP, 1983)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199053 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CHERNOV, VA4
PRESNOVA, Zh2
STEVENS, DA1
EASTY, GC1
AMBROSE, EJ1
PRADHAN, SN1
WEST, WL1
HILLER, SA1
LIDAKS, MJ1
ZIDERMANE, AA1
GERMANE, SK1
GRIGALINOVICH, GA1
DAUVARTS, AZ1
KRAVCHENKO, IM1
PRESS, BO1
HANDLER, AH1
SARRIS, TG1
WILLS, C1
GRUSHINA, AA2
SORKINA, YA1
VERMEL, EM1
TSETLIN, AL1
SAKURAI, Y1
GREKH, IF1
KARLINSKAIA, RS1
TURBINA, IL1
SUKHIN, GM2
PEREVOSHCHIKOVA, KA1
BESLEKOEV, TI1
SURODEIKINA, LN1
GARIBDZHANIAN, BT1
Kulish, OP1
Galkina, KA1
Garkavi, LKh1
Kvakina, EB1
Mulatova, AK1
Taras'iants, FM1
Kavetskiĭ, RE1
Balitskiĭ, KP1
Veksler, IG2
Vetrova, EP1
Vorontsova, AL1
Peliukova, RN1
Bulbuk, GA1
Modest, EJ1
Stenram, U2
Nilsson, E2
Berg, R2
Moskalik, KG1
Kozlov, AP1
Akimov, AA1
Konovalova, NP1
D'iachkovskaia, RF1
Kiseleva, EG1
Yron, I1
Weiss, DW1
Robinson, E1
Cohen, D1
Adelberg, MG1
Mekori, T1
Haber, M1
Merkulov, MF2
Leskova, SG2
Woenckhaus, HJ1
Klemm, D1
Obrecht, P1
Barton, AA1
Barton, M1
Tsyrlina, EV1
Kochetkova, VA1
Morozov, AP1
Bulkina, ZP1
Poliak, NR1
Miuller, NR2
Anisimov, VN1
Ershova, IuA1
Bass-Shadkhan, KhF4
Zakenfel'd, GK1
Liepa, VE2
Birzgale, VP1
Prane, LIu1
Mergina, GR1
Hoshi, A1
Kumagai, K1
Kanzawa, F1
Kuretani, K1
Sorkina, IuA1
Presnova, ZhF1
Kulik, GI2
Pel'kis, FP1
Arkhangel'skaia, AV1
Maliugina, LL1
Pol'kina, RI1
Remizov, AL1
Petrov, AS1
Kraĭz, BO1
Lazarev, NV1
Shelaputina, ZF1
Iavorskaia, NP2
Mashburn, LT1
Schmähl, D1

Reviews

2 reviews available for thiotepa and EHS Tumor

ArticleYear
[Use of optical quantum generators (lasers) in oncology].
    Voprosy onkologii, 1972, Volume: 18, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Basal Cell; Carcinom

1972
[Side-effects of cytostatic therapy with special reference to potential carcinogenic effects].
    Der Internist, 1971, Volume: 12

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bus

1971

Other Studies

51 other studies available for thiotepa and EHS Tumor

ArticleYear
[CHANGES IN DEPOLYMERASE ACTIVITY OF NUCLEIC ACIDS IN RATS WITH TRANSPLANTABLE TUMORS UNDER THE INFLUENCE OF ETHYLENIMINE DERIVATIVES].
    Voprosy onkologii, 1963, Volume: 9

    Topics: Antineoplastic Agents; Aziridines; Clinical Enzyme Tests; Deoxyribonucleases; DNA; Neoplasm Transpla

1963
THE ASSAY OF THE EFFECT OF CHEMICAL AGENTS ON TUMOUR INVASION USING CHICK EMBRYOS.
    British journal of cancer, 1963, Volume: 17

    Topics: Animals; Astrocytoma; Biological Assay; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chick Embry

1963
FURTHER STUDIES ON THE EFFECT OF THIOTEPA ON THE SYNTHESIS OF PROTEIN AND NUCLEIC ACIDS IN TUMOR-BEARING MICE.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; DNA; DNA, Neoplasm; Glycine; Lymphoma, Non-Hodgkin; Metabolism; Mice; Neoplasm Proteins; Ne

1964
ANTITUMOROUS SUBSTANCES WITH RADIOMIMETIC AND RADIOPROTECTIVE GROUPS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Acetylcholine; Antineoplastic Agents; Blood Pressure; Carcinoma 256, Walker; Cats; Erythropoiesis; L

1964
CHEMOTHERAPY STUDIES ON PRIMARY TUMOR GRAFTS AND METASTASES IN HAMSTERS AND MICE.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Antineoplastic Agents; Cricetinae; Cyclophosphamide; Dactinomycin; Melphalan; Mice; Mitomycin; Mitom

1964
THE EFFECT PRODUCED BY SOME HORMONES ON THE ANTITUMOUR ACTIVITY OF ETHYLENIMINE AND BETA-CHLORETHYLAMINE DERIVATIVES.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Adrenocorticotropic Hormone; Antineoplastic Agents; Aziridines; Cortisone; Growth Hormone; Neoplasms

1964
[ON THE ANTINEOPLASTIC ACTIVITY OF SOME FUROCOUMARINS].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Furans; Furocoumarins; Khellin;

1964
IN VITRO CULTURE OF YOSHIDA SARCOMA CELLS: METHODS FOR DETERMINING ACQUIRED RESISTANCE TO DRUGS.
    National Cancer Institute monograph, 1964, Volume: 16

    Topics: Animals; Antineoplastic Agents; Azaguanine; Culture Media; Cyclophosphamide; Dactinomycin; Drug Tole

1964
[RESULTS OF THE TREATMENT OF RATS WITH TRANSPLANTED SARCOMA SSK WITH THIOTEPA ASSOCIATED WITH SOME PYRIMIDINE DERIVATIVES].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Antineoplastic Agents; Neoplasm Transplantation; Neoplasms; Pharmacology; Pyrimidines; Research; Sar

1964
[BONE MARROW TRANSPLANTATION IN RATS WITH M-1 SARCOMA AFTER ADMINISTRATION OF TOXIC DOSES OF THIO-TEPA].
    Biulleten' eksperimental'noi biologii i meditsiny, 1965, Volume: 59

    Topics: Animals; Bone Marrow Transplantation; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Exp

1965
THE ACTION OF SOME METABOLIC INHIBITORS UPON THE ACCUMULATION OF AMINO ACIDS AND THE INCORPORATION OF THE LATTER INTO THE PROTEINS OF THE TUMOR CELLS IN VITRO.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Amino Acids; Animals; Antineoplastic Agents; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Glyc

1964
[EFFECT OF BONE MARROW TRANSPLANTATION IN THE TREATMENT OF SARCOMA-M-1 IN RATS WITH THIO-TEPA].
    Voprosy onkologii, 1965, Volume: 11

    Topics: Animals; Bone Marrow Transplantation; Neoplasms; Research; Sarcoma; Sarcoma, Experimental; Thiotepa

1965
[CHANGES IN THE ANTITUMOR ACTIVITY OF THIOPHOSPHAMIDE WITH ADRENALIN UNDER EXPERIMENTAL CONDITIONS].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 58

    Topics: Animals; Epinephrine; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiot

1964
[EFFECT OF THIO-TEPA ON THE BLOOD PROTEIN COMPOSITION IN SARCOMA M-1].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Blood Proteins; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiotepa

1964
[EFFECT OF THIO-TEPA ON THE PHAGOCYTIC ACTIVITY OF LEUKOCYTES (EXPERIMENTAL STUDY)].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Animals; Leukocytes; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiotepa

1964
[Effect of high-altitude hypoxia on the effectiveness of chemotherapy in tumors].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 95, Issue:2

    Topics: Altitude Sickness; Animals; Carcinoma; Cyclophosphamide; Drug Evaluation, Preclinical; Female; Hypox

1983
[Experimental use of antitumor preparations in low doses].
    Voprosy onkologii, 1981, Volume: 27, Issue:7

    Topics: Adaptation, Physiological; Animals; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Resista

1981
[Tilorone, a synthetic immunostimulator possessing antitumor activity].
    Voprosy onkologii, 1977, Volume: 23, Issue:11

    Topics: Animals; Antibody-Producing Cells; Antineoplastic Agents; Drug Evaluation, Preclinical; Fluorenes; I

1977
[Effect of thiophosphamide on carcinomia in rats with sarcoma SSK].
    Voprosy onkologii, 1976, Volume: 22, Issue:9

    Topics: Animals; Female; Neoplastic Cells, Circulating; Rats; Sarcoma, Experimental; Thiotepa

1976
[The effect of extirpation of the adrenals on changes in the perimural hydrolysis of carbohydrates in animals with sarcoma 45 and receiving thiophosphamide and 5-fluorouracil].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Amylases; Animals; Diet; Female; Fluorouracil; Intestinal Mucosa; Int

1973
Formal discussion: future prospects in leukemia chemotherapy.
    Cancer research, 1965, Volume: 25, Issue:9

    Topics: Animals; Dactinomycin; Floxuridine; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; N

1965
The effect of some cancer-therapeutic agents on the transplantability and growth of an SV40 sarcoma in rat.
    Acta pathologica et microbiologica Scandinavica, 1968, Volume: 72, Issue:3

    Topics: Animals; Cyclophosphamide; Neoplasm Transplantation; Rats; Sarcoma, Experimental; Simian virus 40; T

1968
Effects of some cancer-chemotherapeutic agents, especially cyclophosphamide, on an SV40 sarcoma in rat.
    Zeitschrift fur Krebsforschung, 1969, Volume: 72, Issue:2

    Topics: Animals; Azathioprine; Cyclophosphamide; Fluorouracil; Hydrocortisone; Neoplasm Transplantation; Rat

1969
[Toxicity and antineoplastic activity of a new thio-TEPA analog].
    Voprosy onkologii, 1973, Volume: 19, Issue:1

    Topics: Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Squa

1973
Immunotherapeutic studies in mice with the methanol-extraction residue (mer) fraction of BCG: solid tumors.
    National Cancer Institute monograph, 1973, Volume: 39

    Topics: Animals; Antigens, Bacterial; BCG Vaccine; Benzopyrenes; Cyclophosphamide; Female; Fibrosarcoma; Flu

1973
[Use of transplantability indices of tumor cells for evaluation of the cytotoxic effect of antineoplastic agents in vitro].
    Farmakologiia i toksikologiia, 1972, Volume: 35, Issue:1

    Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Fluorouracil; Leukemia, Experimental; Male; Melp

1972
[Studies on the lengthening of the survival time of RF mice with retothelial sarcoma by the combination of radiotherapy and chemotherapy].
    Klinische Wochenschrift, 1965, Jul-15, Volume: 43, Issue:14

    Topics: Animals; Antineoplastic Agents; Azirines; Lymphoma, Large B-Cell, Diffuse; Mice; Radiation Effects;

1965
Electron microscope studies on the effect of thiotepa on the cytoplasm of fibrosarcoma cells grown in tissue culture.
    British journal of cancer, 1965, Volume: 19, Issue:3

    Topics: Animals; Culture Techniques; Cytoplasm; Fibrosarcoma; Mice; Microscopy, Electron; Sarcoma, Experimen

1965
[Influence of chemotherapeutic agents combined with the extract of eleutherococcus senticosus on rise and development of the "SSK" tumour metastases].
    Voprosy onkologii, 1965, Volume: 11, Issue:10

    Topics: Animals; Antineoplastic Agents; Drug Synergism; Melphalan; Mice; Neoplasm Metastasis; Plants, Medici

1965
An experimental comparative study of the distribution of P32-labelled Thio-Tepa and P32 tag.
    Meditsinskaia radiologiia, 1967, Volume: 12, Issue:4

    Topics: Animals; Phosphorus Isotopes; Rats; Sarcoma, Experimental; Thiotepa

1967
[Effect of prodigiozan on the therapeutic effect and toxicity of some antitumor preparations].
    Antibiotiki, 1968, Volume: 13, Issue:1

    Topics: Adrenal Glands; Animals; Antineoplastic Agents; Body Weight; Drug Synergism; Leukocytes; Liver; Melp

1968
[Vitamin B-12 in the chemotherapy of experimental tumors].
    Voprosy onkologii, 1968, Volume: 14, Issue:4

    Topics: Animals; Mice; Nitrogen Mustard Compounds; Rats; Sarcoma, Experimental; Thiotepa; Vitamin B 12

1968
[A study of the combined effect of antitumorous alkylating agents and vitamin B 12 on a model of a metastasizing tumor].
    Voprosy onkologii, 1966, Volume: 12, Issue:4

    Topics: Animals; Lung Neoplasms; Lymphatic Metastasis; Melphalan; Neoplasm Metastasis; Neoplasm Transplantat

1966
[On the anti-tumor action of N,N'-malonyl-bis-ethyleneimine].
    Voprosy onkologii, 1967, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Injections, Intraperitoneal; Mice; Rats; S

1967
[Effect of thiophosphamide and DEPA on the mitotic activity of tumorous and normal tissue of rats with sarcoma 45].
    Voprosy onkologii, 1968, Volume: 14, Issue:10

    Topics: Animals; Bone Marrow; Heart; Male; Mitosis; Rats; Sarcoma, Experimental; Thiotepa

1968
[Serum protein fractions of sarcomatous mice subjected to the combined effect of zymosan and thio-TEPA].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Animals; Blood Proteins; Male; Rats; Sarcoma, Experimental; Thiotepa; Zymosan

1968
[Levels of properdin in the serum of rats submitted to the combined effect of zymosan and thio-TEPA].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Animals; Neoplasm Transplantation; Properdin; Rats; Sarcoma, Experimental; Thiotepa; Transplantation

1968
[Various biologic indices in sarcomatous rats administered thio-TEPA together with zymosan].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Animals; Male; Rats; Sarcoma, Experimental; Thiotepa; Zymosan

1968
[Study of the hemo-stimulating effect of zymosan according to findings in the blood and bone marrow of normal subjects and experimental animals with tumors during their treatment with thio-TEPA].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Animals; Bone Marrow; Male; Rabbits; Rats; Sarcoma, Experimental; Thiotepa; Zymosan

1968
[Aminotransferase activity in the liver, blood plasma and tumors of mice with sarcoma M-1 under the influence of thio-TEPA and zymosan].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Animals; Liver; Male; Rats; Sarcoma, Experimental; Thiotepa; Transaminases; Zymosan

1968
[Comparative evaluation of the effect of ionizing radiation, thio-TEPA and their combined use on various indices of the blood of mice diseased with sarcoma M-1].
    Klinika i lechenie zlokachestvennykh novoobrazovanii, 1968, Volume: 11

    Topics: Animals; Blood Proteins; Male; Rats; Sarcoma, Experimental; Thiotepa

1968
Sensitivity of Nakahara-Fukuoka sarcoma to antitumor agents, especially to purine analogs.
    Gan, 1969, Volume: 60, Issue:1

    Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Fluorouracil; Hydrocortisone; Me

1969
[The influence of desoxycorticosterone on the anti-tumor effect of thiophosphamide in intact and adrenalectomized rats with sarcoma 45].
    Voprosy onkologii, 1969, Volume: 15, Issue:2

    Topics: Adrenal Glands; Animals; Desoxycorticosterone; Male; Rats; Sarcoma; Sarcoma, Experimental; Thiotepa

1969
[The effect of antineoplastic alkylating agents on the serum protein fraction of rats with sarcoma 45].
    Voprosy onkologii, 1969, Volume: 15, Issue:7

    Topics: Alkylating Agents; Animals; Blood Protein Disorders; Blood Protein Electrophoresis; Cyclophosphamide

1969
[Dynamics of the cerebral ammonia-glutamine system in rat tumor carriers following surgical and chemotherapeutic removal of the tumor].
    Biulleten' eksperimental'noi biologii i meditsiny, 1969, Volume: 67, Issue:2

    Topics: Ammonia; Animals; Brain Chemistry; Glutamates; Glutamine; Male; Rats; Sarcoma, Experimental; Thiotep

1969
[Experimental basis for methods of determining individual sensitivity of tumors to alkylating antitumor preparations].
    Biulleten' eksperimental'noi biologii i meditsiny, 1969, Volume: 68, Issue:12

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cyclophosphamide; Male; Melphalan; Neoplasms, Exp

1969
[The anti-tumor effect of several mono- and di-chlor-sym.triazine derivatives].
    Voprosy onkologii, 1970, Volume: 16, Issue:6

    Topics: Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Female; Leukopenia; Lung Neoplasms; Lympho

1970
[Resistance of malignant tumors to chemotherapeutic effects].
    Voprosy onkologii, 1970, Volume: 16, Issue:12

    Topics: Animals; Lymphoma, Non-Hodgkin; Male; Rats; Sarcoma, Experimental; Thiotepa

1970
[Effect of thiophosphamide on the incorporation of H3-thymidine into the DNA of cells of surviving transplantable tumor sections sensitive and resistant toward the agent].
    Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:1

    Topics: Animals; Body Weight; Depression, Chemical; DNA, Neoplasm; In Vitro Techniques; Male; Mice; Rats; Sa

1971
Combination chemotherapy with L-asparaginase (EC-2) using P1798 lymphosarcoma.
    Cancer, 1971, Volume: 28, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cyclophosphami

1971
[Probit-analysis in the evaluation of the selectivity of antineoplastic effect of agents].
    Voprosy onkologii, 1971, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Evaluation Studies as Topic

1971