thiotepa and Di Guglielmo Disease studies

thiotepa and Di Guglielmo Disease

thiotepa has been researched along with Di Guglielmo Disease in 4 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

Excerpt	Relevance	Reference
"Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0."	1.26	Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977)
" Pharmacokinetic studies have shown that these compounds possess particular affinity towards tumor tissue."	1.26	Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs. ( Djachkovskaya, RF; Emanuel, NM; Konovalova, NP, 1976)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

4 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Reimer, RR	1
Hoover, R	1
Fraumeni, JF	1
Young, RC	1
Emanuel, NM	1
Konovalova, NP	1
Djachkovskaya, RF	1
Ruffner, BW	1
Khomchenovskiĭ, EI	1

Studies

Reimer, RR

Hoover, R

Fraumeni, JF

Young, RC

Emanuel, NM

Konovalova, NP

Djachkovskaya, RF

Ruffner, BW

Khomchenovskiĭ, EI

Other Studies

4 other studies available for thiotepa and Di Guglielmo Disease

Article	Year
Acute leukemia after alkylating-agent therapy of ovarian cancer. The New England journal of medicine, 1977, Jul-28, Volume: 297, Issue:4 Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil;	1977
Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs. Cancer treatment reports, 1976, Volume: 60, Issue:11 Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinic	1976
Letter: Androgen role in erythroleukemia after treatment with alkylating agents. Annals of internal medicine, 1974, Volume: 81, Issue:1 Topics: Adult; Alkylating Agents; Androgens; Carcinoma, Intraductal, Noninfiltrating; Chlorambucil; Cytarabi	1974
[A comparative quantitative study of the anti-leukemia activity of hexaphosphamide, various anti-leukemia preparations and x-rays]. Biulleten' eksperimental'noi biologii i meditsiny, 1968, Volume: 65, Issue:4 Topics: Acute Disease; Animals; Antineoplastic Agents; Leukemia, Erythroblastic, Acute; Leukemia, Experiment	1968

Article

Year

Acute leukemia after alkylating-agent therapy of ovarian cancer.

The New England journal of medicine, 1977, Jul-28, Volume: 297, Issue:4

Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil;

1977

Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs.

Cancer treatment reports, 1976, Volume: 60, Issue:11

Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinic

1976

Letter: Androgen role in erythroleukemia after treatment with alkylating agents.

Annals of internal medicine, 1974, Volume: 81, Issue:1

Topics: Adult; Alkylating Agents; Androgens; Carcinoma, Intraductal, Noninfiltrating; Chlorambucil; Cytarabi

1974

[A comparative quantitative study of the anti-leukemia activity of hexaphosphamide, various anti-leukemia preparations and x-rays].

Biulleten' eksperimental'noi biologii i meditsiny, 1968, Volume: 65, Issue:4

Topics: Acute Disease; Animals; Antineoplastic Agents; Leukemia, Erythroblastic, Acute; Leukemia, Experiment

1968