thiotepa has been researched along with Dermatitis Medicamentosa in 5 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| " TBC combined with thiotepa is highly toxic to the skin with various cutaneous manifestations." | 1.56 | Skin toxicity following treosulfan-thiotepa-fludarabine-based conditioning regimen in non-malignant pediatric patients undergoing hematopoietic stem cell transplantation. ( Altman Kohl, S; Even-Or, E; Molho-Pessach, V; Stepensky, P; Zaidman, I, 2020) |
| "Patients with multiple bladder tumors, bladder tumors inaccessible to endoscopic resection, or lesions too extensive to completely resect, or with medial contraindications for endoscopic resection procedures, were included in these studies." | 1.27 | Combined thiotepa and mitomycin C instillation therapy for low-grade superficial bladder tumor. ( Gonder, M; Hu, KN; Khan, AS; Kim, A; Soroff, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Even-Or, E | 1 |
| Altman Kohl, S | 1 |
| Zaidman, I | 1 |
| Stepensky, P | 1 |
| Molho-Pessach, V | 1 |
| Van Schandevyl, G | 1 |
| Bauters, T | 1 |
| Legha, SS | 1 |
| Ajani, JA | 1 |
| Blumenschein, GR | 1 |
| Hortobagyi, GN | 1 |
| Buzdar, AU | 1 |
| Kalifa, C | 1 |
| Hartmann, O | 1 |
| Demeocq, F | 1 |
| Vassal, G | 1 |
| Couanet, D | 1 |
| Terrier-Lacombe, MJ | 1 |
| Valteau, D | 1 |
| Brugieres, L | 1 |
| Lemerle, J | 1 |
| Hu, KN | 1 |
| Kim, A | 1 |
| Khan, AS | 1 |
| Soroff, H | 1 |
| Gonder, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Tolerance Adjuvant High-Dose Thiotepa With Peripheral Stem Cell Rescue Associated With Conventional Chemotherapy in Children and Adults With Relapsed Osteosarcoma[NCT00978471] | Phase 2 | 44 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for thiotepa and Dermatitis Medicamentosa
| Article | Year |
|---|---|
High-dose busulfan and thiotepa with autologous bone marrow transplantation in childhood malignant brain tumors: a phase II study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation | 1992 |
4 other studies available for thiotepa and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Skin toxicity following treosulfan-thiotepa-fludarabine-based conditioning regimen in non-malignant pediatric patients undergoing hematopoietic stem cell transplantation.
Topics: Busulfan; Child; Child, Preschool; Drug Eruptions; Drug Therapy, Combination; Female; Hematopoietic | 2020 |
Thiotepa-induced cutaneous toxicity in pediatric patients: Case report and implementation of preventive care guidelines.
Topics: Adolescent; Cerebellar Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Drug Eruptions | 2019 |
Combination chemotherapy of metastatic breast carcinoma with cyclophosphamide, adriamycin, and peptichemio.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; | 1984 |
Combined thiotepa and mitomycin C instillation therapy for low-grade superficial bladder tumor.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Transitional Cell; Cystosco | 1985 |