Page last updated: 2024-11-05

thiotepa and Delayed Hypersensitivity

thiotepa has been researched along with Delayed Hypersensitivity in 3 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"The effect of anti-cancer agents on the delayed hypersensitivity reaction was thought to be due to elimination of suppressor T cell activity."1.26Enhancement of delayed hypersensitivity reaction with varieties of anti-cancer drugs. A common biological phenomenon. ( Goto, M; Kitano, M; Mitsuoka, A; Sugiyama, M, 1981)
"Patients with recurrent superficial bladder tumors have been treated by vesical and intradermal administration of Bacillus Calmette-Guerin."1.26Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors. ( Bruce, AW; Eidinger, D; Morales, A, 1976)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goto, M1
Mitsuoka, A1
Sugiyama, M1
Kitano, M1
Morales, A1
Eidinger, D1
Bruce, AW1
Venenson, EV1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravesical Instillation Therapy With Bacillus Calmette-Guérin (BCG) and Sequential BCG and Electromotive Mitomycin-C (EMDA-MCC) in Patients With High-risk Non-muscle-invasive Bladder Carcinoma[NCT03664869]Phase 3300 participants (Anticipated)Interventional2018-10-26Recruiting
The Difference of Two Year Recurrence Rate According to Anesthetic Method During Transurethral Resection of Bladder Mass in Patients With Non-muscle Invasive Bladder Cancer: Prospective, Randomized, Clinical Phase II Study[NCT03597087]289 participants (Anticipated)Interventional2018-07-19Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for thiotepa and Delayed Hypersensitivity

ArticleYear
Enhancement of delayed hypersensitivity reaction with varieties of anti-cancer drugs. A common biological phenomenon.
    The Journal of experimental medicine, 1981, Jul-01, Volume: 154, Issue:1

    Topics: Animals; Antineoplastic Agents; Carbazilquinone; Cell Cycle; Cyclophosphamide; Humans; Hypersensitiv

1981
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.
    The Journal of urology, 1976, Volume: 116, Issue:2

    Topics: Aged; BCG Vaccine; Carcinoma, Transitional Cell; Female; Humans; Hypersensitivity, Delayed; Immunoth

1976
[Mechanism of action of cytostatic agents in rheumatoid arthritis].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:1

    Topics: Adult; Antibodies; Antineoplastic Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Chlorambucil;

1974