Page last updated: 2024-11-05

thiotepa and Cystitis

thiotepa has been researched along with Cystitis in 12 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.

Research Excerpts

ExcerptRelevanceReference
"The National Bladder Cancer Group undertook a study to determine the effectiveness and toxicity of mitomycin in patients who failed on thiotepa."9.05Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group. ( Barton, B; Hazra, TA; Heney, NM; Kluskens, L; Koontz, WW; Soloway, MS; Trump, DL, 1985)
"Eosinophilic cystitis is a rare form of an allergic cystitis."6.39Intravesical thiotepa-induced eosinophilic cystitis. ( Choe, JM; Kirkemo, AK; Sirls, LT, 1995)
"The National Bladder Cancer Group undertook a study to determine the effectiveness and toxicity of mitomycin in patients who failed on thiotepa."5.05Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group. ( Barton, B; Hazra, TA; Heney, NM; Kluskens, L; Koontz, WW; Soloway, MS; Trump, DL, 1985)
"Eosinophilic cystitis is a rare form of an allergic cystitis."2.39Intravesical thiotepa-induced eosinophilic cystitis. ( Choe, JM; Kirkemo, AK; Sirls, LT, 1995)
"Serious leukopenia was found in 2 of the 48 patients receiving the combined instillation therapy but we concluded that this was not attributable to the use of urokinase."1.25The prophylactic use of thio-tepa and urokinase in transitional cell carcinoma of the bladder: a preliminary report. ( Hisazumi, H; Misaki, T; Miyazaki, K; Naito, K; Uchibayashi, T, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nissenkorn, I1
Slutzker, D1
Schujman, E1
Servadio, C1
Choe, JM1
Kirkemo, AK1
Sirls, LT1
Fleming, RA1
Cruz, JM1
Webb, CD1
Kucera, GL1
Perry, JJ1
Hurd, DD1
Hisazumi, H1
Uchibayashi, T1
Naito, K1
Misaki, T1
Miyazaki, K1
Koontz, WW1
Heney, NM1
Soloway, MS1
Kluskens, L1
Hazra, TA1
Trump, DL1
Barton, B1
Pavone-Macaluso, M1
Veenema, RJ2
Romas, NA1
Fingerhut, B1
Mayor, G1
Dean, AL1
Uson, AC1
Roberts, M1
Longo, F1
Lunglmayr, G2
Czech, K2

Reviews

2 reviews available for thiotepa and Cystitis

ArticleYear
Intravesical thiotepa-induced eosinophilic cystitis.
    Urology, 1995, Volume: 46, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Cystitis; Eosinophilia; Humans; Male; Thiotepa

1995
Chemotherapy for bladder cancer.
    Urology, 1974, Volume: 3, Issue:2

    Topics: Administration, Topical; Alkylating Agents; Blood Cell Count; Carcinoma, Papillary; Cystitis; Cystos

1974

Trials

2 trials available for thiotepa and Cystitis

ArticleYear
Urinary elimination of cyclophosphamide alkylating metabolites and free thiols following two administration schedules of high-dose cyclophosphamide and mesna.
    Bone marrow transplantation, 1996, Volume: 17, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Carboplatin; Cyclophosphamide; Cystitis; Drug Administrati

1996
Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group.
    Urology, 1985, Volume: 26, Issue:4 Suppl

    Topics: Administration, Topical; Biopsy; Carcinoma in Situ; Clinical Trials as Topic; Cystitis; Cystoscopy;

1985

Other Studies

8 other studies available for thiotepa and Cystitis

ArticleYear
The influence of lower urinary tract infection on the recurrence rate of superficial transitional cell carcinoma of the bladder.
    The Journal of urology, 1983, Volume: 130, Issue:4

    Topics: Aged; Animals; Anti-Bacterial Agents; Carcinoma, Transitional Cell; Cystitis; Dogs; Female; Humans;

1983
[Bladder tumors].
    Minerva medica, 1981, Apr-14, Volume: 72, Issue:15

    Topics: Carcinoma in Situ; Cystitis; Diagnosis, Differential; Doxorubicin; Humans; Thiotepa; Urinary Bladder

1981
The prophylactic use of thio-tepa and urokinase in transitional cell carcinoma of the bladder: a preliminary report.
    The Journal of urology, 1975, Volume: 114, Issue:3

    Topics: Adolescent; Adult; Aged; Carcinoma, Transitional Cell; Cystitis; Drug Therapy, Combination; Endopept

1975
Chemotherapy of vesical and prostatic tumours.
    British journal of urology, 1971, Volume: 43, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cobalt Isotopes; Cystitis; Daunorubic

1971
[Bladder lesions due to local administration or ingestion of antiseptic, cytostatic and radioactive compounds].
    Journal d'urologie et de nephrologie, 1973, Volume: 79, Issue:12 Pt 2

    Topics: Anti-Infective Agents, Urinary; Antineoplastic Agents; Cresols; Cystitis; Humans; Iodine Radioisotop

1973
Thiotepa bladder instillations: therapy and prophylaxis for superficial bladder tumors.
    The Journal of urology, 1969, Volume: 101, Issue:5

    Topics: Blood Platelet Disorders; Cystitis; Cystoscopy; Humans; Leukopenia; Neoplasm Recurrence, Local; Solu

1969
[Experimental animal and clinical studies of the absorption of trisaziridylthiophosphoric acid (Thio-Thepa) from the bladder].
    Osterreichische Zeitschrift fur Erforschung und Bekampfung der Krebskrankheit, 1970, Volume: 25, Issue:6

    Topics: Absorption; Animals; Cystitis; Humans; Male; Papilloma; Rabbits; Thiotepa; Urinary Bladder; Urinary

1970
Absorption studies on intraluminal thio-tepa for topical cytostatic treatment of low-stage bladder tumors.
    The Journal of urology, 1971, Volume: 106, Issue:1

    Topics: Body Fluids; Bone Marrow; Cystitis; Epithelium; Humans; Methods; Papilloma; Pyridines; Thiotepa; Uri

1971