thiotepa has been researched along with Colonic Neoplasms in 30 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No excess mortality from noncolorectal cancers was apparent, nor were there significant differences by treatment: TSPA (22/22), FdUrd (9/12), and surgery only (50/42)." | 2.65 | Late effects of low-dose adjuvant chemotherapy in colorectal cancer. ( Boice, JD; Fraumeni, JF; Greene, MH; Higgins, GA; Keehn, RJ, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (93.33) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HOLDEN, WD | 2 |
| DIXON, WJ | 2 |
| ETALA, E | 1 |
| SOFIA, V | 1 |
| ROMERO, LM | 1 |
| BRINDLEY, CO | 1 |
| HIGGINS, GA | 3 |
| FLYNN, T | 1 |
| GILLESPIE, J | 1 |
| DWIGHT, RW | 2 |
| KABAKOW, B | 1 |
| ALBAUM, H | 1 |
| ANTOPOL, W | 1 |
| BLINICK, G | 1 |
| SUSSMAN, L | 1 |
| GINZBURG, L | 1 |
| KAITMAZOVA-KHUDZHADZE, RG | 1 |
| BATEMAN, JC | 1 |
| CARLTON, HN | 1 |
| WHITLEY, R | 1 |
| Gilbert, JM | 1 |
| Korman, DB | 1 |
| Krutova, TV | 1 |
| Shamajev, VI | 1 |
| Boice, JD | 1 |
| Greene, MH | 1 |
| Keehn, RJ | 2 |
| Fraumeni, JF | 1 |
| Gisselbrecht, C | 1 |
| Belpomme, D | 1 |
| Mignot, L | 1 |
| Marty, M | 1 |
| Mathé, G | 1 |
| Boiron, M | 1 |
| Ahmann, FR | 1 |
| Fleischer, I | 1 |
| Wainstein, R | 1 |
| de Gibson, AM | 1 |
| Cagetti, M | 1 |
| Casula, G | 1 |
| Uccheddu, A | 1 |
| Dionne, LJ | 1 |
| Kibrite, A | 1 |
| Martin, M | 1 |
| Chauffert, B | 1 |
| Dimanche-Boitrel, MT | 1 |
| Genne, P | 1 |
| Petit, JM | 1 |
| Onier, N | 1 |
| Jeannin, JF | 1 |
| Nakamura, S | 1 |
| Kashimoto, S | 1 |
| Kajikawa, F | 1 |
| Nakata, K | 1 |
| Bibby, MC | 2 |
| McDermott, BJ | 1 |
| Double, JA | 2 |
| Phillips, RM | 2 |
| Loadman, PM | 1 |
| Burgess, L | 1 |
| Shabanov, AN | 1 |
| Kizhaev, VI | 1 |
| Dorokhin, IF | 1 |
| Zogorianskiĭ, IA | 1 |
| Griffen, WO | 1 |
| Humphrey, L | 1 |
| Sosin, H | 1 |
| Lipton, A | 1 |
| Kenis, Y | 1 |
| Grossi, CE | 1 |
| Nealon, TF | 1 |
| Rousselot, LM | 1 |
| Hill, GJ | 1 |
| Larsen, RR | 1 |
| Kuzma, JW | 1 |
| Horton, J | 1 |
| Olson, K | 1 |
| Johnston, GS | 1 |
| Jones, AE | 1 |
5 reviews available for thiotepa and Colonic Neoplasms
| Article | Year |
|---|---|
[CHEMOTHERAPY BY PERFUSION FOR CANCER OF THE STOMACH AND COLON].
Topics: Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Flox | 1963 |
[Current trends of complementary therapy in radical surgery of colo-rectal cancer].
Topics: Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Postoperative Care; P | 1979 |
[Symposium on carcinoma of colon and rectum: 4. The role of adjuvant therapy with surgery in cancers of the colon and rectum].
Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunosuppressive Agents; Neoplasm Metastasis; Nitrosourea | 1978 |
The prognosis and management of recurrent abdominal malignancies.
Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Ca | 1969 |
Chemotherapy of residual disease in solid tumours.
Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun | 1971 |
5 trials available for thiotepa and Colonic Neoplasms
| Article | Year |
|---|---|
Adjuvant chemotherapy of large bowel cancer.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Floxu | 1982 |
Late effects of low-dose adjuvant chemotherapy in colorectal cancer.
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; Hu | 1980 |
Adjuvant chemotherapy of colorectal carcinoma.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neo | 1982 |
The use of triethylenethiophosphoramide as an adjuvant to the surgical treatment of colorectal carcinoma.
Topics: Adult; Aged; Black or African American; Colonic Neoplasms; Ethnology; Female; Humans; Injections, In | 1967 |
Factors influencing survival after resection in cancer of the colon and rectum.
Topics: Adult; Age Factors; Aged; Colonic Neoplasms; Humans; Lymphatic Metastasis; Middle Aged; Prognosis; R | 1969 |
20 other studies available for thiotepa and Colonic Neoplasms
| Article | Year |
|---|---|
A study of the use of triethylenethiophosphoramide as an adjuvant to surgery in the treatment of colorectal cancer.
Topics: Antineoplastic Agents; Colonic Neoplasms; Colorectal Neoplasms; Humans; Rectal Neoplasms; Rectum; Th | 1962 |
METHODOLOGY OF PRELIMINARY CHEMOTHERAPEUTIC TRIALS IN PATIENTS WITH MALIGNANT SOLID TUMORS.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Colonic Neoplasms; Cyclophosp | 1963 |
EFFECT OF SPLENECTOMY ON TOLERANCE TO THIO-TEPA.
Topics: Colonic Neoplasms; Dogs; Drug Tolerance; Gastrectomy; Mortality; Neoplasms; Splenectomy; Stomach Neo | 1964 |
ADJUVANT CHEMOTHERAPY IN CANCER OF THE LARGE BOWEL. AN INTERIM REPORT OF THE VETERANS ADMINISTRATION SURGICAL ADJUVANT CANCER CHEMOTHERAPY STUDY.
Topics: Adenocarcinoma; Chemotherapy, Adjuvant; Colonic Neoplasms; Geriatrics; Neoplasms; Postoperative Comp | 1964 |
SERIAL ENZYME CHANGES IN CANCER PATIENTS UNDERGOING CHEMOTHERAPY.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Enzyme Tests; Colonic Neoplasms; D-Alani | 1964 |
[TREATMENT OF MALIGNANT TUMORS WITH TRIETHYLNETHIOPHOSPHAMIDE].
Topics: Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Humans; Laryngeal Neoplasms; Lung Neoplasms; Neop | 1963 |
LOCAL ADJUVANT CHEMOTHERAPY IN THE SURGICAL MANAGEMENT OF CANCER.
Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; Intestin | 1964 |
The effect of thiophosphamide on the proliferative activity of human tumor cells cultured in vivo in diffusion chambers.
Topics: Animals; Breast Neoplasms; Cell Division; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Mice; M | 1984 |
Chemotherapy of carcinomas of the digestive tract.
Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Esop | 1982 |
[Adjuvant treatment in surgery of colon and rectal cancer].
Topics: Colonic Neoplasms; Fluorouracil; Humans; Immunotherapy; Prognosis; Rectal Neoplasms; Thiotepa | 1982 |
[Experimental chemotherapy of peritoneal carcinomatosis of colonic origin in rats].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Disease Models, Anim | 1992 |
Combination effect of recombinant human interleukin 1 alpha with antitumor drugs on syngeneic tumors in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Col | 1991 |
Influence of the tissue distribution of ThioTEPA and its metabolite, TEPA, on the response of murine colon tumours.
Topics: Adenocarcinoma; Animals; Azirines; Colonic Neoplasms; Female; Male; Mice; Mice, Inbred Strains; Sex | 1987 |
Experimental correlations of in vitro drug sensitivity with in vivo responses to ThioTEPA in a panel of murine colon tumours.
Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Colony-Forming Units Assay; Dose-Response | 1988 |
[Combination of chemotherapy and surgical treatment of malignant tumors].
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Female; Hodgkin Disease | 1967 |
Chemotherapy of cancer of the colon and rectum.
Topics: Antineoplastic Agents; Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; Nitrosourea Compounds; | 1972 |
Adjuvant chemotherapy in resectable cancer of the colon and rectum.
Topics: Colonic Neoplasms; Fluorouracil; Humans; Postoperative Complications; Rectal Neoplasms; Thiotepa | 1972 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; | 1972 |
[Are combinations more effective than monotherapy in the matter of antiocancer chemotherapy?].
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Synergism; Female; Fluorouracil; Fl | 1968 |
Sequential liver scanning.
Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; F | 1969 |