thiotepa has been researched along with Chylopericardium in 10 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was performed in order to investigate the long-term effects of intracavitary treatment with thiotepa in the reduction of pericardial effusion (PE) recurrences." | 10.21 | Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa. ( Cardinale, D; Cipolla, CM; Civelli, M; Colleoni, M; Fiorentini, C; Lamantia, G; Martinoni, A, 2004) |
| "Patients with malignant pericardial effusions were treated with intracavitary thiotepa (15 mg on days 1, 3, and 5) through an indwelling pericardial cannula after extraction of as much pericardial fluid as possible on day 0." | 9.08 | Intracavitary chemotherapy with thiotepa in malignant pericardial effusions: an active and well-tolerated regimen. ( Beretta, F; Cipolla, G; Colleoni, M; De Pas, T; Fontana, M; Gallino, A; Goldhirsch, A; Graffeo, R; Marone, C; Martinelli, G; Martinoni, C; Zampino, G, 1998) |
| " This study was performed in order to investigate the long-term effects of intracavitary treatment with thiotepa in the reduction of pericardial effusion (PE) recurrences." | 6.21 | Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa. ( Cardinale, D; Cipolla, CM; Civelli, M; Colleoni, M; Fiorentini, C; Lamantia, G; Martinoni, A, 2004) |
| "Patients with malignant pericardial effusions were treated with intracavitary thiotepa (15 mg on days 1, 3, and 5) through an indwelling pericardial cannula after extraction of as much pericardial fluid as possible on day 0." | 5.08 | Intracavitary chemotherapy with thiotepa in malignant pericardial effusions: an active and well-tolerated regimen. ( Beretta, F; Cipolla, G; Colleoni, M; De Pas, T; Fontana, M; Gallino, A; Goldhirsch, A; Graffeo, R; Marone, C; Martinelli, G; Martinoni, C; Zampino, G, 1998) |
| " The following protocols are proposed: CIRP (colchicine in recurrent pericarditis)--colchicine vs placebo in chronic/recurring pericarditis without pericardiocentesis; TRIPE (triamcinolone in pericardial effusion)--intrapericardial instillation of triamcinolone + 6 months colchicine vs pericardial puncture without instillation + 6 months colchicine; NEPIN (neoplastic effusion and pericardial instillation)--pericardiocentesis and drainage + intrapericardial instillation of cisplatin or thiotepa." | 3.70 | New directions in diagnosis and treatment of pericardial disease. A project of the Taskforce on Pericardial Disease of the World Heart Federation. ( Maisch, B; Ristić, AD; Seferovic, PM, 2000) |
| "Pericardial effusion is a known complication of many advanced malignancies, with strong impact both on quality of life and prognosis." | 2.43 | [Treatment of neoplastic pericardial effusions]. ( Martinoni, A, 2006) |
| "A 56-year-old female with breast cancer after left partial mastectomy and subaxillary lymph node dissection was treated with adjuvant chemoradiotherapy." | 1.33 | [A case of recurrent breast cancer complicated with pericardial effusions and cardiac tamponade]. ( Ishiguro, A; Mitobe, S; Munakata, M; Okada, R; Sakata, Y; Shitara, K; Tomioka, R, 2006) |
| "Patients with breast cancer as their primary malignancy survived significantly longer after drainage than did all others (p = 0." | 1.30 | Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions. ( Burt, ME; Ginsberg, RJ; Girardi, LN, 1997) |
| "Pericardial effusions are often present in patients suffering from tumoral diseases, especially lung and breast cancers." | 1.28 | [Pericardial effusion in patients with malignant neoplasms]. ( Beretta, F; Cavalli, F; Marone, C; Martinelli, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maisch, B | 2 |
| Rupp, H | 1 |
| Ristic, A | 1 |
| Pankuweit, S | 1 |
| GOLDMAN, BS | 1 |
| PEARSON, FG | 1 |
| Martinoni, A | 2 |
| Cipolla, CM | 1 |
| Cardinale, D | 1 |
| Civelli, M | 1 |
| Lamantia, G | 1 |
| Colleoni, M | 2 |
| Fiorentini, C | 1 |
| Shitara, K | 1 |
| Munakata, M | 1 |
| Ishiguro, A | 1 |
| Okada, R | 1 |
| Tomioka, R | 1 |
| Mitobe, S | 1 |
| Sakata, Y | 1 |
| Girardi, LN | 1 |
| Ginsberg, RJ | 1 |
| Burt, ME | 1 |
| Martinelli, G | 2 |
| Beretta, F | 2 |
| Marone, C | 2 |
| Gallino, A | 1 |
| Fontana, M | 1 |
| Graffeo, R | 1 |
| Zampino, G | 1 |
| De Pas, T | 1 |
| Cipolla, G | 1 |
| Martinoni, C | 1 |
| Goldhirsch, A | 1 |
| Ristić, AD | 1 |
| Seferovic, PM | 1 |
| Cavalli, F | 1 |
| Smith, FE | 1 |
| Lane, M | 1 |
| Hudgins, PT | 1 |
2 reviews available for thiotepa and Chylopericardium
| Article | Year |
|---|---|
Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa.
Topics: Antineoplastic Agents, Alkylating; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Ins | 2004 |
[Treatment of neoplastic pericardial effusions].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Heart Neoplasms; Humans; Peric | 2006 |
3 trials available for thiotepa and Chylopericardium
| Article | Year |
|---|---|
Pericardioscopy and epi- and pericardial biopsy - a new window to the heart improving etiological diagnoses and permitting targeted intrapericardial therapy.
Topics: Adult; Aged; Algorithms; Anti-Inflammatory Agents; Antineoplastic Agents; Cisplatin; Comparative Eff | 2013 |
Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa.
Topics: Antineoplastic Agents, Alkylating; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Ins | 2004 |
Intracavitary chemotherapy with thiotepa in malignant pericardial effusions: an active and well-tolerated regimen.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Echocardiography; Female; Humans; Instillation, Drug | 1998 |
6 other studies available for thiotepa and Chylopericardium
| Article | Year |
|---|---|
MALIGNANT PERICARDIAL EFFUSION. REVIEW OF HOSPITAL EXPERIENCE AND REPORT OF A CASE SUCCESSFULLY TREATED BY TALC POUDRAGE.
Topics: Breast Neoplasms; Cardiac Surgical Procedures; Cardiac Tamponade; Drug Therapy; Exudates and Transud | 1965 |
[A case of recurrent breast cancer complicated with pericardial effusions and cardiac tamponade].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; B | 2006 |
Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Drainage; | 1997 |
New directions in diagnosis and treatment of pericardial disease. A project of the Taskforce on Pericardial Disease of the World Heart Federation.
Topics: Chronic Disease; Cisplatin; Clinical Trials as Topic; Colchicine; Heart Diseases; Heart Neoplasms; H | 2000 |
[Pericardial effusion in patients with malignant neoplasms].
Topics: Adult; Aged; Breast Neoplasms; Drainage; Drug Therapy, Combination; Echocardiography; Female; Humans | 1992 |
Conservative management of malignant pericardial effusion.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Cardiomegaly; Female; Fluorouracil; Follow-Up Studies | 1974 |