thiotepa and Carcinomatous Meningitis studies

thiotepa and Carcinomatous Meningitis

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

Excerpt	Relevance	Reference
"Treatment of breast cancer meningeal carcinomatosis (MC) relies on intrathecal chemotherapy."	5.39	Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa. ( Bidard, FC; Comte, A; Cottu, PH; Dieras, V; Dorval, T; Guilhaume, MN; Jdid, W; Kriegel, I; Mignot, L; Pierga, JY; Piperno-Neumann, S, 2013)
"Treatment of breast cancer meningeal carcinomatosis (MC) relies on intrathecal chemotherapy."	1.39	Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa. ( Bidard, FC; Comte, A; Cottu, PH; Dieras, V; Dorval, T; Guilhaume, MN; Jdid, W; Kriegel, I; Mignot, L; Pierga, JY; Piperno-Neumann, S, 2013)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

2 (100.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Comte, A	1
Jdid, W	1
Guilhaume, MN	1
Kriegel, I	1
Piperno-Neumann, S	1
Dieras, V	1
Dorval, T	1
Pierga, JY	1
Cottu, PH	1
Mignot, L	1
Bidard, FC	1
Chahal, J	1
Stopeck, A	1
Clarke, K	1
Livingston, RB	1
Chalasani, P	1

Studies

Comte, A

Jdid, W

Guilhaume, MN

Kriegel, I

Piperno-Neumann, S

Dieras, V

Dorval, T

Pierga, JY

Cottu, PH

Mignot, L

Bidard, FC

Chahal, J

Stopeck, A

Clarke, K

Livingston, RB

Chalasani, P

Other Studies

2 other studies available for thiotepa and Carcinomatous Meningitis

Article	Year
Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa. Journal of neuro-oncology, 2013, Volume: 115, Issue:3 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcino	2013
Intravenous thiotepa for treatment of breast cancer-related leptomeningeal carcinomatosis: case series. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:9 Topics: Administration, Intravenous; Adult; Antineoplastic Agents, Alkylating; Breast Neoplasms; Humans; Men	2015

Article

Year

Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa.

Journal of neuro-oncology, 2013, Volume: 115, Issue:3

Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcino

2013

Intravenous thiotepa for treatment of breast cancer-related leptomeningeal carcinomatosis: case series.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:9

Topics: Administration, Intravenous; Adult; Antineoplastic Agents, Alkylating; Breast Neoplasms; Humans; Men

2015