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thiotepa and Carcinoma, Non-Small Cell Lung

thiotepa has been researched along with Carcinoma, Non-Small Cell Lung in 5 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"The principles of dose-response and combination chemotherapy were basic to the design of the initial curative standard-dose treatment regimens for leukemias, lymphomas, and testis cancer."1.28A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients. ( Burke, J; Eder, JP; Elias, A; Frei, E; Hunt, M; Schnipper, LE; Schryber, SM; Shea, TC; Siegel, R; Teicher, BA, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sørensen, JB1
Panday, VR1
van Warmerdam, LJ1
Huizing, MT1
Rodenhuis, S1
Schellens, JH1
Beijnen, JH1
Eder, JP1
Elias, A1
Shea, TC1
Schryber, SM1
Teicher, BA1
Hunt, M1
Burke, J1
Siegel, R1
Schnipper, LE1
Frei, E1
Williams, SF2
Bitran, JD2
Hoffman, PC1
Robin, E2
Fullem, L1
Beschorner, J2
Golick, J1
Golomb, HM1
Kaminer, L1
Westbrook, C1
Jacobs, R1
Ashenhurst, J1
Purl, S1
Schroeder, C1

Trials

1 trial available for thiotepa and Carcinoma, Non-Small Cell Lung

ArticleYear
A single 24-hour plasma sample does not predict the carboplatin AUC from carboplatin-paclitaxel combinations or from a high-dose carboplatin-thiotepa-cyclophosphamide regimen.
    Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplat

1999

Other Studies

4 other studies available for thiotepa and Carcinoma, Non-Small Cell Lung

ArticleYear
Current position of vinorelbine in cancer chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Ci

1995
A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms

1990
High-dose, multiple-alkylator chemotherapy with autologous bone marrow reinfusion in patients with advanced non-small cell lung cancer.
    Cancer, 1989, Jan-15, Volume: 63, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Non-S

1989
A phase I-II study of bialkylator chemotherapy, high-dose thiotepa, and cyclophosphamide with autologous bone marrow reinfusion in patients with advanced cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:2

    Topics: Adult; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantatio

1987