thiotepa has been researched along with Carcinoma, Non-Small Cell Lung in 5 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Excerpt | Relevance | Reference |
---|---|---|
"The principles of dose-response and combination chemotherapy were basic to the design of the initial curative standard-dose treatment regimens for leukemias, lymphomas, and testis cancer." | 1.28 | A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients. ( Burke, J; Eder, JP; Elias, A; Frei, E; Hunt, M; Schnipper, LE; Schryber, SM; Shea, TC; Siegel, R; Teicher, BA, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 3 (60.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sørensen, JB | 1 |
Panday, VR | 1 |
van Warmerdam, LJ | 1 |
Huizing, MT | 1 |
Rodenhuis, S | 1 |
Schellens, JH | 1 |
Beijnen, JH | 1 |
Eder, JP | 1 |
Elias, A | 1 |
Shea, TC | 1 |
Schryber, SM | 1 |
Teicher, BA | 1 |
Hunt, M | 1 |
Burke, J | 1 |
Siegel, R | 1 |
Schnipper, LE | 1 |
Frei, E | 1 |
Williams, SF | 2 |
Bitran, JD | 2 |
Hoffman, PC | 1 |
Robin, E | 2 |
Fullem, L | 1 |
Beschorner, J | 2 |
Golick, J | 1 |
Golomb, HM | 1 |
Kaminer, L | 1 |
Westbrook, C | 1 |
Jacobs, R | 1 |
Ashenhurst, J | 1 |
Purl, S | 1 |
Schroeder, C | 1 |
1 trial available for thiotepa and Carcinoma, Non-Small Cell Lung
Article | Year |
---|---|
A single 24-hour plasma sample does not predict the carboplatin AUC from carboplatin-paclitaxel combinations or from a high-dose carboplatin-thiotepa-cyclophosphamide regimen.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplat | 1999 |
4 other studies available for thiotepa and Carcinoma, Non-Small Cell Lung
Article | Year |
---|---|
Current position of vinorelbine in cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Ci | 1995 |
A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1990 |
High-dose, multiple-alkylator chemotherapy with autologous bone marrow reinfusion in patients with advanced non-small cell lung cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Non-S | 1989 |
A phase I-II study of bialkylator chemotherapy, high-dose thiotepa, and cyclophosphamide with autologous bone marrow reinfusion in patients with advanced cancer.
Topics: Adult; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantatio | 1987 |