Page last updated: 2024-11-05

thiotepa and Carcinoma, Ductal, Breast

thiotepa has been researched along with Carcinoma, Ductal, Breast in 7 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Carcinoma, Ductal, Breast: An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of docetaxel plus thiotepa(TXT/TSPA) and docetaxel plus capecitabine(TXT/CAPE) in patients with metastatic breast cancer."9.15[Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer]. ( Che, L; DI, Lj; Jia, J; Jiang, Hf; Liang, X; Ren, J; Song, Gh; Wang, Xl; Yang, Hb; Yu, J; Zhang, J; Zhou, Xn; Zhu, Yl, 2011)
"Treatment of breast cancer meningeal carcinomatosis (MC) relies on intrathecal chemotherapy."5.39Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa. ( Bidard, FC; Comte, A; Cottu, PH; Dieras, V; Dorval, T; Guilhaume, MN; Jdid, W; Kriegel, I; Mignot, L; Pierga, JY; Piperno-Neumann, S, 2013)
"Our previous work showed thiotepa could eradicate breast cancer stem cells."5.17Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free and overall survival in patients with metastatic breast cancer: reargument of su ( Che, L; Di, L; Jia, J; Jiang, H; Liang, X; Lyerly, HK; Ren, J; Song, G; Wan, F; Wang, X; Yan, Y; Yu, J; Zhang, J; Zhou, X; Zhu, Y, 2013)
"To evaluate the efficacy and safety of docetaxel plus thiotepa(TXT/TSPA) and docetaxel plus capecitabine(TXT/CAPE) in patients with metastatic breast cancer."5.15[Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer]. ( Che, L; DI, Lj; Jia, J; Jiang, Hf; Liang, X; Ren, J; Song, Gh; Wang, Xl; Yang, Hb; Yu, J; Zhang, J; Zhou, Xn; Zhu, Yl, 2011)
"Treatment of breast cancer meningeal carcinomatosis (MC) relies on intrathecal chemotherapy."1.39Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa. ( Bidard, FC; Comte, A; Cottu, PH; Dieras, V; Dorval, T; Guilhaume, MN; Jdid, W; Kriegel, I; Mignot, L; Pierga, JY; Piperno-Neumann, S, 2013)
"Four cases had stage II or III breast cancer with over 10 positive axillary lymph nodes who had received radical surgical resection."1.30[Combination of high-dose chemotherapy with autologous hematopoietic stem cell transplantation for recurrent and high-risk breast cancer: a pilot study]. ( Han, X; Pan, F; Shi, Y, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
de Boo, L1
Cimino-Mathews, A1
Lubeck, Y1
Daletzakis, A1
Opdam, M1
Sanders, J1
Hooijberg, E1
van Rossum, A1
Loncova, Z1
Rieder, D1
Trajanoski, Z1
Vollebergh, M1
Sobral-Leite, M1
van de Vijver, K1
Broeks, A1
van der Wiel, R1
van Tinteren, H1
Linn, S1
Horlings, HM1
Kok, M1
Comte, A1
Jdid, W1
Guilhaume, MN1
Kriegel, I1
Piperno-Neumann, S1
Dieras, V2
Dorval, T2
Pierga, JY2
Cottu, PH1
Mignot, L1
Bidard, FC1
Yu, J2
DI, Lj1
Song, Gh1
Che, L2
Jiang, Hf1
Zhu, Yl1
Liang, X2
Jia, J2
Zhang, J2
Yang, Hb1
Wang, Xl1
Zhou, Xn1
Ren, J2
Di, L1
Song, G1
Zhu, Y1
Yan, Y1
Jiang, H1
Wan, F1
Wang, X1
Zhou, X1
Lyerly, HK1
Stemmer, SM1
Hardan, I1
Brenner, HJ1
Rizel, S1
Mouret, E1
Laurence, V1
Beuzeboc, P1
PalangiƩ, T1
Jouve, M1
Vincent-Salomon, A1
Scholl, S1
Extra, JM1
Asselain, B1
Pouillart, P1
Shi, Y1
Pan, F1
Han, X1

Trials

3 trials available for thiotepa and Carcinoma, Ductal, Breast

ArticleYear
Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 127

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Prote

2020
[Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2011, Feb-18, Volume: 43, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Capec

2011
Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free and overall survival in patients with metastatic breast cancer: reargument of su
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2013, Volume: 15, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinom

2013

Other Studies

4 other studies available for thiotepa and Carcinoma, Ductal, Breast

ArticleYear
Survival of breast cancer patients with meningeal carcinomatosis treated by intrathecal thiotepa.
    Journal of neuro-oncology, 2013, Volume: 115, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcino

2013
High-dose chemotherapy and autologous stem cell transplant in women with de novo chemosensitive metastatic breast cancer.
    American journal of clinical oncology, 2004, Volume: 27, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinoma, Duc

2004
Prognostic value of persistent node involvement after neoadjuvant chemotherapy in patients with operable breast cancer.
    British journal of cancer, 2000, Volume: 83, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Carcinoma, Du

2000
[Combination of high-dose chemotherapy with autologous hematopoietic stem cell transplantation for recurrent and high-risk breast cancer: a pilot study].
    Zhonghua yi xue za zhi, 1999, Volume: 79, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Carcinoma, Duc

1999