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thiotepa and Cancer of Kidney

thiotepa has been researched along with Cancer of Kidney in 24 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
" These cases demonstrate that it is feasible and safe to perform HSCT in pediatric patients with low nGFR using melphalan- and thiotepa-based preparative therapy."2.72Autologous hematopoietic stem cell transplant with melphalan and thiotepa is safe and feasible in pediatric patients with low normalized glomerular filtration rate. ( Gross, TG; Grovas, A; Klopfenstein, K; Rosselet, R; Termuhlen, AM, 2006)
"Renal cell carcinoma has been shown to be responsive to immunotherapy with recombinant human cytokines and may be an ideal model for exploring this novel therapy."2.41Nonablative hematopoietic cell transplantation for the treatment of metastatic renal cell carcinoma. ( Abonour, R; Logan, TF; Nelson, RP, 2002)
"The tumors included 18 neuroblastomas, 5 soft tissue sarcomas, 2 hepatoblastomas, and 1 Wilms tumor."1.42Perioperative management after high-dose chemotherapy with autologous or allogeneic hematopoietic stem cell transplantation for pediatric solid tumors. ( Hashii, Y; Miyamura, T; Nakahata, K; Nara, K; Oue, T; Owari, M; Uehara, S; Ueno, T; Usui, N, 2015)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's2 (8.33)18.2507
2000's5 (20.83)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uehara, S1
Oue, T1
Nakahata, K1
Nara, K1
Ueno, T1
Owari, M1
Usui, N1
Miyamura, T1
Hashii, Y1
Lu, DD1
Boorjian, SA1
Raman, JD1
Nelson, RP1
Logan, TF1
Abonour, R1
Kremens, B1
Gruhn, B1
Klingebiel, T1
Hasan, C1
Laws, HJ1
Koscielniak, E1
Hero, B1
Selle, B1
Niemeyer, C1
Finckenstein, FG1
Schulz, A1
Wawer, A1
Zintl, F1
Graf, N1
BATEMAN, JC1
CARLTON, HN1
WHITLEY, R1
Campbell, AD1
Cohn, SL1
Reynolds, M1
Seshadri, R1
Morgan, E1
Geissler, G1
Rademaker, A1
Marymount, M1
Kalapurakal, J1
Haut, PR1
Duerst, R1
Kletzel, M1
Termuhlen, AM1
Grovas, A1
Klopfenstein, K1
Rosselet, R1
Gross, TG1
Wong, SH1
Poon, GP1
Bretheau, D1
Lechevallier, E1
Jean, F1
Rampal, M1
Coulange, C1
Seaman, EK1
Slawin, KM1
Benson, MC1
Izhogin, DG1
Boiarshinov, VK1
Dolgonolov, IS1
Iankelevich, MIa1
Ptushkina, EA1
Mentkevich, GL1
Hahn, DM1
Schimpff, SC1
Ruckdeschel, JC1
Wiernik, PH1
Carter, SK1
Wasserman, TH1
Berry, RJ1
Laing, AH1
Wells, J1
Staquet, M1
De Kock, ML1
Breytenbach, IH1
Rutishauser, G1
Klein, U1
Furnari, S1
Pavone-Macaluso, M1
Veroux, G1
Mattea, E1
Wallace, JD1
Franksson, C1
Bergstrand, A1
Ljungdahl, I1
Magnusson, G1
Nordenstam, H1
Brenner, MW1
Holsti, LR1
Perttala, Y1
Godby, AF1
Sonntag, RW1
Cosentino, BJ1
Mannes, P1
Derriks, R1
Moens, R1
Heynen, E1
Terent'eva, TG1
Fomina, IP1
Navashin, SM1
Martochkina, GA1

Reviews

3 reviews available for thiotepa and Cancer of Kidney

ArticleYear
Nonablative hematopoietic cell transplantation for the treatment of metastatic renal cell carcinoma.
    Bone marrow transplantation, 2002, Volume: 30, Issue:12

    Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Combined Modality Therapy; C

2002
Treatment options for upper tract transitional-cell carcinoma.
    The Urologic clinics of North America, 1993, Volume: 20, Issue:2

    Topics: Administration, Topical; BCG Vaccine; Carcinoma, Transitional Cell; Combined Modality Therapy; Human

1993
Free radicals and neoplasia--some experimental findings and some possible implications.
    CRC critical reviews in radiological sciences, 1972, Volume: 3, Issue:1

    Topics: Adenofibroma; Animals; Breast Neoplasms; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Carcinoma

1972

Trials

4 trials available for thiotepa and Cancer of Kidney

ArticleYear
Autologous hematopoietic stem cell transplant with melphalan and thiotepa is safe and feasible in pediatric patients with low normalized glomerular filtration rate.
    Pediatric transplantation, 2006, Volume: 10, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Combined Modality Therapy; Drug Therapy, Combin

2006
[High-dose thiotepa chemotherapy in children].
    Voprosy onkologii, 2000, Volume: 46, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child

2000
Single-agent therapy for renal cell carcinoma: CCNU, vinblastine, thioTEPA, or bleomycin.
    Cancer treatment reports, 1977, Volume: 61, Issue:8

    Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Drug Evaluation; Female; Humans; Kidney Neoplasms;

1977
The randomized clinical trial: a prerequisite for rational therapy.
    European urology, 1976, Volume: 2, Issue:6

    Topics: Clinical Trials as Topic; Cyclophosphamide; Diethylstilbestrol; Double-Blind Method; Doxorubicin; Fe

1976

Other Studies

17 other studies available for thiotepa and Cancer of Kidney

ArticleYear
Perioperative management after high-dose chemotherapy with autologous or allogeneic hematopoietic stem cell transplantation for pediatric solid tumors.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2015, Volume: 25, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj

2015
Intravesical chemotherapy use after radical nephroureterectomy: A national survey of urologic oncologists.
    Urologic oncology, 2017, Volume: 35, Issue:3

    Topics: Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Chem

2017
High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma.
    Bone marrow transplantation, 2002, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Combined Modal

2002
LOCAL ADJUVANT CHEMOTHERAPY IN THE SURGICAL MANAGEMENT OF CANCER.
    Surgery, 1964, Volume: 56

    Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; Intestin

1964
Treatment of relapsed Wilms' tumor with high-dose therapy and autologous hematopoietic stem-cell rescue: the experience at Children's Memorial Hospital.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jul-15, Volume: 22, Issue:14

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cy

2004
Intrapelvic thiotepa for re-recurrence of transitional cell carcinoma of the renal pelvis in a solitary kidney.
    British journal of urology, 1984, Volume: 56, Issue:1

    Topics: Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Pelvis; Middle Aged; Neoplasm

1984
[Tumors of the superior urinary tract and associated bladder tumors: clinical and etiological aspects].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1993, Volume: 3, Issue:6

    Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Cystectomy; Female; Follow-Up Studies; Humans; I

1993
The chemotherapy of urologic cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Co

1975
Fresh explant culture of human tumours in vitro and the assessment of sensitivity to cytotoxic chemotherapy.
    British journal of cancer, 1975, Volume: 31, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Culture Techniques; Drug Evaluation, Preclini

1975
Local excision and topical thiotepa in the treatment of transitional cell carcinoma of the renal pelvis: a case report.
    The Journal of urology, 1986, Volume: 135, Issue:3

    Topics: Aged; Carcinoma, Transitional Cell; Combined Modality Therapy; Female; Humans; Kidney Neoplasms; Kid

1986
[The so-called benign tumors of the urinary tract].
    Helvetica chirurgica acta, 1973, Volume: 40, Issue:5

    Topics: Adult; Female; Hematuria; Humans; Kidney Neoplasms; Male; Neoplasm Recurrence, Local; Papilloma; Thi

1973
Cancer chemotherapy in urology.
    Urologia internationalis, 1971, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal

1971
Renal carcinoma (hypernephroma) occurring in 5 siblings.
    The Journal of urology, 1972, Volume: 108, Issue:1

    Topics: Adenocarcinoma; Adult; Biopsy; Female; Fluorouracil; Humans; Kidney; Kidney Neoplasms; Male; Middle

1972
The study by graphical analysis of the growth of human tumours and metastases of the lung.
    British journal of cancer, 1967, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Kidney Neoplasms; Lung Neoplasms; Mathemati

1967
Hypernephroma with metastasis to the mandibular gingiva. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1967, Volume: 23, Issue:5

    Topics: Adenocarcinoma; Adult; Biopsy; Bone Resorption; Gingival Diseases; Humans; Kidney Neoplasms; Male; M

1967
[Antineoplastic polychemotherapy in thoracic pathology].
    Le Poumon et le coeur, 1968, Volume: 24, Issue:1

    Topics: Adrenalectomy; Aged; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cortisone; Cyclop

1968
[The sensitivity of human kidney cancer in cultures to antitumor preparations].
    Voprosy onkologii, 1971, Volume: 17, Issue:7

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cells, Cultured; Humans; In Vitro Techniques; Ki

1971