thiotepa has been researched along with Brain Edema in 2 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, O | 1 |
| Mogami, H | 1 |
| Higashi, H | 1 |
| Hayakawa, T | 1 |
| Kuroda, R | 1 |
| Kanai, N | 1 |
2 other studies available for thiotepa and Brain Edema
| Article | Year |
|---|---|
[Chemotherapy of malignant brain tumors by intermittent and continuous intra-arterial infusion of antitumor agents--clinical study].
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Arteries; Brain Edema; Brain Neoplasms; C | 1966 |
Selection of cytostatic agents for intrathecal chemotherapy of brain tumor.
Topics: Animals; Brain Edema; Cyclophosphamide; Injections, Spinal; Mitomycins; Nitrogen Mustard Compounds; | 1967 |