thiotepa has been researched along with Body Weight in 14 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the relationship of microvascular events in the bone marrow to the development of and the recovery from bone atrophy, we examined quantitatively and qualitatively trabecular bone, sinusoids and haematopoietic tissue in the metaphysis of the tibia of rats given thiotepa, an antitumour drug derived from nitrogen mustards." | 7.68 | Microvascular events in bone marrow related to development of and recovery from bone atrophy in thiotepa-treated rats. ( Nakata, K; Nishimoto, M; Shibayama, Y, 1993) |
| "To clarify the relationship of microvascular events in the bone marrow to the development of and the recovery from bone atrophy, we examined quantitatively and qualitatively trabecular bone, sinusoids and haematopoietic tissue in the metaphysis of the tibia of rats given thiotepa, an antitumour drug derived from nitrogen mustards." | 3.68 | Microvascular events in bone marrow related to development of and recovery from bone atrophy in thiotepa-treated rats. ( Nakata, K; Nishimoto, M; Shibayama, Y, 1993) |
| " With human bladder cancer cells in culture, cytotoxicity of thiotepa was increased up to 10-fold (P less than 0." | 3.67 | In vivo and in vitro enhanced antitumor effects by pentoxifylline in human cancer cells treated with thiotepa. ( Alley, MC; Chen, ZY; Fingert, HJ; Googe, PB; Pardee, AB; Pu, AT, 1988) |
| " Dosage of thiotepa was significantly related to percentage of sperm head morphological abnormalities assayed by light microscopy." | 1.27 | Toxicity of thiotepa on mouse spermatogenesis as determined by dual-parameter flow cytometry. ( Baer, RK; Evenson, DP; Gesch, RW; Jost, LK, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsutsumi, E | 1 |
| Momonami, A | 1 |
| Hori, H | 1 |
| Kitagawa, Y | 1 |
| SYRKIN, AB | 2 |
| CHUMAKOV, VM | 1 |
| Ariyuki, F | 1 |
| Higaki, K | 1 |
| Yasuda, M | 1 |
| Shibayama, Y | 1 |
| Nishimoto, M | 1 |
| Nakata, K | 1 |
| Evenson, DP | 1 |
| Baer, RK | 1 |
| Jost, LK | 1 |
| Gesch, RW | 1 |
| Tanum, G | 1 |
| Sønstevold, A | 1 |
| Engeset, A | 1 |
| Fingert, HJ | 1 |
| Pu, AT | 1 |
| Chen, ZY | 1 |
| Googe, PB | 1 |
| Alley, MC | 1 |
| Pardee, AB | 1 |
| Potopal'skiĭ, AI | 1 |
| Shishka, GV | 1 |
| Iordan, AM | 1 |
| Veksler, IG | 1 |
| Tanimura, T | 1 |
| MacGregor, AB | 1 |
| Macleod, DA | 1 |
| Thomson, JW | 1 |
| Hayakawa, T | 1 |
| Yamada, R | 1 |
| Kanai, N | 1 |
| Kuroda, R | 1 |
| Ushio, Y | 1 |
| Higashi, H | 1 |
| Mogami, H | 1 |
| Merkulov, MF | 1 |
| Shelaputina, ZF | 1 |
| Iavorskaia, NP | 1 |
| Leskova, SG | 1 |
1 review available for thiotepa and Body Weight
| Article | Year |
|---|---|
Design of cancer chemotherapy: tailored sensitivity assays.
Topics: Animals; Antineoplastic Agents; Body Weight; Chlorambucil; Melphalan; Nitrogen Mustard Compounds; Or | 1980 |
13 other studies available for thiotepa and Body Weight
| Article | Year |
|---|---|
Evaluation of single-dose RBC Pig-a and PIGRET assays in detecting the mutagenicity of thiotepa in rats.
Topics: Animals; Body Weight; Erythrocytes; Male; Membrane Proteins; Mutagenicity Tests; Mutagens; Rats; Rat | 2016 |
INFLUENCE OF SOME ANTITUMOR DRUGS ON BODY AND ORGANS GROWTH IN RATS.
Topics: Adrenal Glands; Antineoplastic Agents; Body Weight; Bone and Bones; Brain; Chlorambucil; Diaphragm; | 1964 |
A study of fetal growth retardation in teratological tests: an examination of the relationship between body weight and ossification of coccygeal vertebrae in mouse and rat fetuses.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Body Weight; Coccyx; Female; Fetal Growth Retardation; | 1980 |
Microvascular events in bone marrow related to development of and recovery from bone atrophy in thiotepa-treated rats.
Topics: Animals; Atrophy; Body Weight; Bone and Bones; Bone Marrow; Female; Rats; Rats, Wistar; Thiotepa; Ti | 1993 |
Toxicity of thiotepa on mouse spermatogenesis as determined by dual-parameter flow cytometry.
Topics: Animals; Body Weight; Chromatin; Dose-Response Relationship, Drug; Flow Cytometry; Male; Mice; Mice, | 1986 |
The effect of pretreatment with thio-TEPA and cytosine arabinoside on megakaryocytopoiesis in rats given a sublethal dose of thio-TEPA.
Topics: Animals; Body Weight; Cytarabine; Hematopoiesis; Intestinal Mucosa; Male; Megakaryocytes; Melphalan; | 1987 |
In vivo and in vitro enhanced antitumor effects by pentoxifylline in human cancer cells treated with thiotepa.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cells, Cultured; Drug Synergis | 1988 |
[Antitumor action of berberinol thiophosphamide in experimental tumors in mice].
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, Drug; Fe | 1974 |
[Effect of prodigiozan on the therapeutic effect and toxicity of some antitumor preparations].
Topics: Adrenal Glands; Animals; Antineoplastic Agents; Body Weight; Drug Synergism; Leukocytes; Liver; Melp | 1968 |
Modification of the teratogenic effects of certain antineoplastic agents by combined treatment with vitamins.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Drug Antagonism; Drug Synergism; Female; Fetal De | 1968 |
Combined chemotherapy in the treatment of malignant effusions.
Topics: Alkylating Agents; Antineoplastic Agents; Ascites; Ascitic Fluid; Blood Cell Count; Blood Platelets; | 1969 |
Intrathecal chemotherapy. Selection of cytostatic agents.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Body Weight; Brain Neoplasms; Cyclophosphamide; | 1970 |
[Effect of thiophosphamide on the incorporation of H3-thymidine into the DNA of cells of surviving transplantable tumor sections sensitive and resistant toward the agent].
Topics: Animals; Body Weight; Depression, Chemical; DNA, Neoplasm; In Vitro Techniques; Male; Mice; Rats; Sa | 1971 |