thiotepa has been researched along with Blast Crisis in 1 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Blast Crisis: An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-six adults with chronic myelogenous leukemia (CML) in second or greater chronic phase, accelerated phase, or blast crisis underwent marrow or blood stem cell transplantation from an HLA-matched sibling using high-dose thiotepa, busulfan and cyclophosphamide (TBC) as the preparative regimen." | 5.09 | Thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced chronic myelogenous leukemia. ( Andersson, B; Champlin, R; Deisseroth, AB; Gajewski, J; Giralt, S; Ippoliti, C; Khouri, I; Körbling, M; Lee, MS; Mehra, R; Przepiorka, D; Thall, P; van Besien, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Przepiorka, D | 1 |
| Khouri, I | 1 |
| Thall, P | 1 |
| Mehra, R | 1 |
| Lee, MS | 1 |
| Ippoliti, C | 1 |
| Giralt, S | 1 |
| Gajewski, J | 1 |
| van Besien, K | 1 |
| Andersson, B | 1 |
| Körbling, M | 1 |
| Deisseroth, AB | 1 |
| Champlin, R | 1 |
1 trial available for thiotepa and Blast Crisis
| Article | Year |
|---|---|
Thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced chronic myelogenous leukemia.
Topics: Adult; Antineoplastic Agents, Alkylating; Blast Crisis; Bone Marrow Transplantation; Busulfan; Cyclo | 1999 |