thiotepa has been researched along with Benign Supratentorial Neoplasms in 4 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients previously treated with surgery, radiation therapy and chemotherapy with a nitrosourea for malignant supratentorial gliomas received a combination of procarbazine, thiotepa and vincristine (P." | 9.07 | Treatment of recurrent malignant supratentorial gliomas with the association of procarbazine, thiotepa and vincristine: a phase II study. ( Ameri, A; Chen, QM; Delattre, JY; Poisson, M, 1993) |
| "Twenty patients previously treated with surgery, radiation therapy and chemotherapy with a nitrosourea for malignant supratentorial gliomas received a combination of procarbazine, thiotepa and vincristine (P." | 5.07 | Treatment of recurrent malignant supratentorial gliomas with the association of procarbazine, thiotepa and vincristine: a phase II study. ( Ameri, A; Chen, QM; Delattre, JY; Poisson, M, 1993) |
| "Supratentorial primitive neuroectodermal tumors (S-PNET) are rare and have a grim prognosis, frequently taking an aggressive course with local relapse and metastatic spread." | 1.33 | Supratentorial primitive neuroectodermal tumors (S-PNET) in children: A prospective experience with adjuvant intensive chemotherapy and hyperfractionated accelerated radiotherapy. ( Casanova, M; Cefalo, G; Collini, P; Ferrari, A; Fossati-Bellani, F; Gandola, L; Giangaspero, F; Luksch, R; Massimino, M; Meazza, C; Pignoli, E; Podda, M; Poggi, G; Polastri, D; Ravagnani, F; Simonetti, F; Spreafico, F; Terenziani, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butturini, AM | 1 |
| Jacob, M | 1 |
| Aguajo, J | 1 |
| Vander-Walde, NA | 1 |
| Villablanca, J | 1 |
| Jubran, R | 1 |
| Erdreich-Epstein, A | 1 |
| Marachelian, A | 1 |
| Dhall, G | 1 |
| Finlay, JL | 1 |
| Pérez-Martínez, A | 1 |
| Lassaletta, A | 1 |
| González-Vicent, M | 1 |
| Sevilla, J | 1 |
| Díaz, MA | 1 |
| Madero, L | 1 |
| Massimino, M | 1 |
| Gandola, L | 1 |
| Spreafico, F | 1 |
| Luksch, R | 1 |
| Collini, P | 1 |
| Giangaspero, F | 1 |
| Simonetti, F | 1 |
| Casanova, M | 1 |
| Cefalo, G | 1 |
| Pignoli, E | 1 |
| Ferrari, A | 1 |
| Terenziani, M | 1 |
| Podda, M | 1 |
| Meazza, C | 1 |
| Polastri, D | 1 |
| Poggi, G | 1 |
| Ravagnani, F | 1 |
| Fossati-Bellani, F | 1 |
| Ameri, A | 1 |
| Poisson, M | 1 |
| Chen, QM | 1 |
| Delattre, JY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors[NCT02653196] | Early Phase 1 | 1 participants (Actual) | Interventional | 2015-09-30 | Terminated (stopped due to The Principal Investigator left the institution.) | ||
| A Phase III Multicenter Study of Intratumoral/Interstitial Therapy With TransMID Compared to Best Standard of Care in Patients With Progressive and/or Recurrent, Non-Resectable Glioblastoma Multiforme[NCT00088400] | Phase 3 | 30 participants | Interventional | 2004-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for thiotepa and Benign Supratentorial Neoplasms
| Article | Year |
|---|---|
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cerebel | 2005 |
Treatment of recurrent malignant supratentorial gliomas with the association of procarbazine, thiotepa and vincristine: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Glioma; Humans; Male; Middle Ag | 1993 |
2 other studies available for thiotepa and Benign Supratentorial Neoplasms
| Article | Year |
|---|---|
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined | 2009 |
Supratentorial primitive neuroectodermal tumors (S-PNET) in children: A prospective experience with adjuvant intensive chemotherapy and hyperfractionated accelerated radiotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Chi | 2006 |