thiotepa has been researched along with Benign Neoplasms in 298 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was performed in order to investigate the long-term effects of intracavitary treatment with thiotepa in the reduction of pericardial effusion (PE) recurrences." | 10.21 | Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa. ( Cardinale, D; Cipolla, CM; Civelli, M; Colleoni, M; Fiorentini, C; Lamantia, G; Martinoni, A, 2004) |
| " This study was performed in order to investigate the long-term effects of intracavitary treatment with thiotepa in the reduction of pericardial effusion (PE) recurrences." | 6.21 | Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa. ( Cardinale, D; Cipolla, CM; Civelli, M; Colleoni, M; Fiorentini, C; Lamantia, G; Martinoni, A, 2004) |
| "A strong relationship has been demonstrated between high systemic exposure to busulfan and the occurrence of hepatic veno-occlusive disease (HVOD) after a busulfan-cyclophosphamide regimen (BU CY)." | 5.10 | In children and adolescents, the pharmacodynamics of high-dose busulfan is dependent on the second alkylating agent used in the combined regimen (melphalan or thiotepa). ( Boland, I; Bouligand, J; Deroussent, A; Hartmann, O; Kalifa, C; Valteau-Couanet, D; Vassal, G, 2003) |
| " We conclude that, independent of effects on neutropenia, severe and cumulative platelet toxicity precludes further escalation of thiotepa dose despite the use of GM-CSF." | 5.07 | Phase I trial of thiotepa in combination with recombinant human granulocyte-macrophage colony-stimulating factor. ( Hudes, GR; LaCreta, FP; McAleer, C; Miller, LL; Nash, S; O'Dwyer, PJ; Ozols, RF; Schilder, R, 1992) |
| "High-dose thiotepa, a polyfunctional alkylating agent used in the treatment of solid tumors in children and adults, has been reported to cause a variety of reactions in the skin, including erythema, blistering, and hyperpigmentation." | 3.74 | Cutaneous effects of thiotepa in pediatric patients receiving high-dose chemotherapy with autologous stem cell transplantation. ( Bayliss, SJ; Hayashi, RJ; Lloyd, BM; Rosman, IS, 2008) |
| "The pharmacokinetics of thiotepa administered as a continuous infusion over 4 days have been studied in 18 patients receiving high-dose thiotepa, cyclophosphamide, and autologous bone marrow reinfusion as treatment for advanced neoplasms." | 3.67 | Pharmacokinetics of continuous-infusion high-dose thiotepa. ( Antman, K; Begg, C; Eder, JP; Elias, A; Flaherty, MD; Furlong, EA; Henner, WD; Shea, TC, 1987) |
| " 5-Fluorouracil (5 FU) is the first chemotherapeutic agent found to have a significant effect on gastrointestinal adenocarcinoma." | 3.64 | PALLIATIVE MANAGEMENT OF GASTROINTESTINAL CANCER. ( HART, GD, 1964) |
| " Pharmacogenetic approaches can identify patients who are at risk of experiencing toxic side effects in high-dose chemotherapy." | 2.73 | Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin. ( Beijnen, JH; Ekhart, C; Huitema, AD; Rodenhuis, S; Smits, PH, 2008) |
| "Busulfan was combined with cyclophosphamide and melphalan (n=30), melphalan (n=27), and thiotepa (n=20)." | 2.73 | Elevated plasma ferritin and busulfan pharmacodynamics during high-dose chemotherapy regimens in children with malignant solid tumors. ( Benhamou, E; Bouligand, J; Drouard-Troalen, L; Grill, J; Hartmann, O; Le Maitre, A; Paci, A; Valteau-Couanet, D; Vassal, G, 2007) |
| " Doses were adapted on day 3 based on pharmacokinetic analyses of cyclophosphamide, 4-hydroxycyclophosphamide, thiotepa, tepa, and carboplatin done on day 1 using a Bayesian algorithm." | 2.71 | Accuracy, feasibility, and clinical impact of prospective Bayesian pharmacokinetically guided dosing of cyclophosphamide, thiotepa, and carboplatin in high-dose chemotherapy. ( Beijnen, JH; de Jonge, ME; Huitema, AD; Rodenhuis, S; Tukker, AC; van Dam, SM, 2005) |
| "The anticancer prodrug cyclophosphamide (CP) is activated by the formation of 4-hydroxycyclophosphamide (4OHCP), which decomposes into phosphoramide mustard (PM)." | 2.71 | Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin. ( Beijnen, JH; de Jonge, ME; Huitema, AD; Rodenhuis, S; van Dam, SM, 2005) |
| " A clear dose-response relationship was evident between the number of CD34+ cells per kilogram infused between the number of CD34+ cells per kilogram infused and neutrophil and platelet engraftment kinetics." | 2.68 | An analysis of engraftment kinetics as a function of the CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy. ( Allen, C; Birch, R; Hazelton, B; Palmer, P; Schwartzberg, L; Weaver, CH; West, W, 1995) |
| "Eleven patients with germ cell cancer relapsing from a complete remission and 7 patients with refractory germ cell cancer and/or an unresectable partial remission received salvage chemotherapy with one to two courses of carboplatin (800 mg/m2) and etoposide (500 mg/m2 on days 1, 3, and 5), followed by either one or two courses of carboplatin (1600 mg/m2), cyclophosphamide (6 g/m2), and thiotepa (480 mg/m2) divided over 4 days with autologous bone marrow transplantation and/or peripheral stem cell support." | 2.68 | Pilot study of a high-dose carboplatin-based salvage strategy for relapsing or refractory germ cell cancer. ( Richel, DJ; Rodenhuis, S; Schornagel, JH; ten Bokkel Huinink, WW; van der Wall, E; Vlasveld, LT, 1995) |
| "ThioTEPA was given once as a 1-h i." | 2.68 | A phase I/II study of high-dose cyclophosphamide, cisplatin, and thioTEPA followed by autologous bone marrow and granulocyte colony-stimulating factor-primed peripheral-blood progenitor cells in patients with advanced malignancies. ( Affrontil, ML; Berchuck, A; Berry, DA; Clarke-Person, D; Egorin, MJ; Elkordy, M; Gilbert, C; Gupton, C; Hussein, AM; Jones, RB; Peters, WP; Petros, WP; Ross, M; Rubin, P; Shpall, EJ; Soper, J; Vredenburgh, JJ, 1996) |
| "ThioTEPA was administered intravenously every three weeks, at a dose of 65 mg/m2." | 2.68 | A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study. ( Balis, FM; Bleyer, WA; Broxson, E; Geyer, JR; Heideman, R; Krailo, MD; Poplack, D; Sato, JK, 1996) |
| "Melphalan was given i." | 2.68 | High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors. ( Ater, J; Chan, KW; Choroszy, M; Herzog, C; Jaffe, N; Korbling, M; Petropoulos, D, 1997) |
| " There were no toxic deaths." | 2.67 | Feasibility and toxicity study of a high-dose chemotherapy regimen for autotransplantation incorporating carboplatin, cyclophosphamide and thiotepa. ( Baars, JW; Mandjes, I; Pinedo, HM; Richel, DJ; Rodenhuis, S; Schornagel, JH; Vlasveld, LT, 1992) |
| "ThioTEPA was administered i." | 2.67 | Phase I/pharmacokinetic reevaluation of thioTEPA. ( Cole, D; DeLap, RJ; DeVito, J; Engstrom, PF; LaCreta, F; Litwin, S; O'Dwyer, PJ; Peter, R; Poplack, D; Tartaglia, L, 1991) |
| "Serious neurological adverse events (NAE) have occurred during treatment with high-dose thiotepa regimens of children with high-risk solid tumours." | 1.48 | High-dose thiotepa-related neurotoxicity and the role of tramadol in children. ( Demirdjian, S; Dufour, C; Laplanche, A; Lemare, F; Maritaz, C; Valteau-Couanet, D, 2018) |
| "However, survivors of brain tumors and any survivor who received high-dose neurotoxic treatment reported the lowest rates of achieving milestones of psychosexual development, whereas sexual and relationship status satisfaction were found to be related to relationship status." | 1.46 | Psychosexual development and satisfaction in long-term survivors of childhood cancer: Neurotoxic treatment intensity as a risk indicator. ( Bajwa, RPS; Gerhardt, CA; Hagedoorn, M; Keim, MC; Lehmann, V; Olshefski, RS; Tuinman, MA; Winning, AM, 2017) |
| "These findings suggest anticancer potential of glutamate antagonists." | 1.31 | Glutamate antagonists limit tumor growth. ( Ikonomidou, C; Rzeski, W; Turski, L, 2001) |
| "Patients with breast cancer as their primary malignancy survived significantly longer after drainage than did all others (p = 0." | 1.30 | Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions. ( Burt, ME; Ginsberg, RJ; Girardi, LN, 1997) |
| "The thiotepa was quantitated using a modification of a previously published gas chromatographic method." | 1.28 | Pharmacokinetics of high dose thiotepa in children undergoing autologous bone marrow transplantation. ( Kearns, GL; Kletzel, M; Thompson, HC; Wells, TG, 1992) |
| "Forty patients with refractory solid tumors or non-Hodgkin's lymphoma were treated with high-dose cyclophosphamide, thiotepa, and carmustine (BCNU), followed by autologous stem cell rescue, in a phase I dose escalation study." | 1.28 | High-dose tri-alkylator chemotherapy with autologous stem cell rescue in patients with refractory malignancies. ( Bitran, JD; Garner, M; Kaminer, LS; Moormeier, JA; Williams, SF, 1990) |
| " This regimen can be safely administered on an outpatient basis, with adequate control of gastrointestinal symptoms achieved by standard antiemetics and intermittent dosing with meals." | 1.28 | Phase I trial of escalating pentoxifylline dose with constant dose thiotepa. ( Dezube, BJ; Eder, JP; Pardee, AB, 1990) |
| "The principles of dose-response and combination chemotherapy were basic to the design of the initial curative standard-dose treatment regimens for leukemias, lymphomas, and testis cancer." | 1.28 | A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients. ( Burke, J; Eder, JP; Elias, A; Frei, E; Hunt, M; Schnipper, LE; Schryber, SM; Shea, TC; Siegel, R; Teicher, BA, 1990) |
| " The plasma and cerebrospinal fluid (CSF) pharmacokinetic parameters of TT and its major active metabolite tepa (TP) were also evaluated." | 1.28 | Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa. ( Balis, F; Cole, DE; Ettinger, LJ; Gillespie, A; Heideman, RL; Packer, RJ; Reaman, GH; Sam, J; Sato, J; Singher, LJ, 1989) |
| " We conclude that high-dose thiotepa results in similar pharmacokinetic values to conventional doses with no apparent dose-dependent variation." | 1.27 | Human plasma pharmacokinetics of thiotepa following administration of high-dose thiotepa and cyclophosphamide. ( Ackland, SP; Bitran, JD; Choi, KE; Egorin, MJ; Ratain, MJ; Sinkule, JA; Williams, SF, 1988) |
| "A pleural effusion is a frequent complication of malignant disease." | 1.26 | Management of malignant pleural effusion. ( Bennett, JM; Greenwald, DW; Phillips, C, 1978) |
| " Pharmacokinetic studies have shown that these compounds possess particular affinity towards tumor tissue." | 1.26 | Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs. ( Djachkovskaya, RF; Emanuel, NM; Konovalova, NP, 1976) |
| "The topography of the neoplasm had no influence on the I." | 1.25 | Immunological overshoot phenomenon following cancer chemotherapy: significance in prognosis evaluation of solid tumors. ( Dubois, JB; Serrou, B, 1975) |
| " Timing and dosage are also considered." | 1.24 | SOME PROBLEMS IN THE CHEMOTHERAPY OF SOLID TUMOURS. ( ARONOVITCH, M; GROSZMAN, M; KAHANA, LM, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 239 (80.20) | 18.7374 |
| 1990's | 36 (12.08) | 18.2507 |
| 2000's | 16 (5.37) | 29.6817 |
| 2010's | 6 (2.01) | 24.3611 |
| 2020's | 1 (0.34) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Battipaglia, G | 1 |
| Mauff, K | 1 |
| Wendel, L | 1 |
| Angelucci, E | 1 |
| Mohty, M | 1 |
| Arcese, W | 1 |
| Santarone, S | 1 |
| Rubio, MT | 1 |
| Kroger, N | 1 |
| Fox, ML | 1 |
| Blaise, D | 1 |
| Iori, AP | 1 |
| Fanin, R | 1 |
| Chalandon, Y | 1 |
| Pioltelli, P | 1 |
| Marotta, G | 1 |
| Chiusolo, P | 1 |
| Sever, M | 1 |
| Solano, C | 1 |
| Contentin, N | 1 |
| de Wreede, LC | 1 |
| Czerw, T | 1 |
| Hernandez-Boluda, JC | 1 |
| Hayden, P | 1 |
| McLornan, D | 1 |
| Yakoub-Agha, I | 1 |
| Maritaz, C | 1 |
| Lemare, F | 1 |
| Laplanche, A | 1 |
| Demirdjian, S | 1 |
| Valteau-Couanet, D | 4 |
| Dufour, C | 1 |
| Cho, KM | 1 |
| Kim, YJ | 1 |
| Kim, SH | 1 |
| Kim, JW | 1 |
| Lee, JO | 1 |
| Han, JH | 1 |
| Lee, KW | 1 |
| Kim, JH | 1 |
| Kim, CY | 1 |
| Bang, SM | 1 |
| Kim, IA | 1 |
| Kim, JS | 1 |
| Lee, JS | 1 |
| Lehmann, V | 1 |
| Tuinman, MA | 1 |
| Keim, MC | 1 |
| Winning, AM | 1 |
| Olshefski, RS | 1 |
| Bajwa, RPS | 1 |
| Hagedoorn, M | 1 |
| Gerhardt, CA | 1 |
| Ekhart, C | 1 |
| Rodenhuis, S | 11 |
| Smits, PH | 1 |
| Beijnen, JH | 8 |
| Huitema, AD | 7 |
| Riethdorf, S | 1 |
| Pantel, K | 1 |
| de Jonge, ME | 4 |
| Mathôt, RA | 2 |
| Dalesio, O | 1 |
| BATEMAN, JC | 5 |
| MCCABE, M | 1 |
| ISRAELS, MC | 2 |
| LEONARD, BJ | 2 |
| WILKINSON, JF | 2 |
| YAMAGUCHI, H | 1 |
| TERASHITA, N | 1 |
| TABUCHI, Y | 1 |
| IKEDA, E | 1 |
| FUKUI, S | 1 |
| MCDONALD, GO | 1 |
| LIVINGSTON, C | 1 |
| BOYLES, CF | 1 |
| COLE, WH | 2 |
| MOORE, GE | 2 |
| WEHR, WH | 1 |
| WATSON, TG | 1 |
| BELTRAN, A | 1 |
| SMART, MC | 1 |
| ANDERSON, MC | 1 |
| STALEY, CJ | 1 |
| SCANLON, EF | 2 |
| PRESTON, FW | 1 |
| THOMAS, BM | 1 |
| FISHER, GS | 1 |
| SCHELL, RF | 1 |
| HALL, BE | 1 |
| MILLER, BJ | 1 |
| FARELL, DM | 1 |
| KISTENMACHER, JC | 1 |
| DAVIS, PL | 1 |
| SHUMWAY, MH | 1 |
| SIU, B | 1 |
| RAVINA, A | 1 |
| PESTEL, M | 1 |
| ULTMANN, JE | 1 |
| HYMAN, GA | 1 |
| GELLHORN, A | 1 |
| OLSON, KB | 2 |
| SHAY, H | 1 |
| SUN, DC | 1 |
| LEONE, LA | 3 |
| HANSBARGER, LC | 1 |
| NOLLEY, ED | 1 |
| MELLETTE, SJ | 1 |
| McIVER, FA | 1 |
| CURRERI, AR | 1 |
| RUSSO, FR | 1 |
| HOGLE, GS | 1 |
| SCHILLING, RF | 1 |
| JAESCHKE, WH | 1 |
| GRECO, T | 1 |
| MAGALINI, SI | 1 |
| GRINBERG, R | 1 |
| AWA, A | 1 |
| IAKUBCHIK, FM | 1 |
| DUNNING, WF | 1 |
| CURTIS, MR | 1 |
| ARMAGHAN, V | 1 |
| McKENZIE, D | 1 |
| PRADHAN, SN | 2 |
| WEST, WL | 2 |
| BAIRD, GM | 1 |
| STEWARD, JD | 1 |
| KOSAREVA, AN | 1 |
| MAIRANSAEV, AKh | 2 |
| MILLER, DM | 1 |
| WOLFF, JP | 1 |
| JONES, HC | 1 |
| SWINNEY, J | 1 |
| EDWARDS, MH | 1 |
| RATHMELL, TK | 1 |
| ENGLANDER, O | 1 |
| SARANGI, A | 1 |
| FLOKSZTRUMPF, M | 1 |
| ISGRO, A | 1 |
| LYONS, A | 1 |
| EDELSTYN, G | 1 |
| MALHERBE, E | 1 |
| SEALY, R | 2 |
| HELMAN, P | 2 |
| ANDERSON, J | 1 |
| HANO, K | 1 |
| IWATA, H | 1 |
| AKASHI, A | 1 |
| BIERMAN, HR | 1 |
| REEVE, TS | 1 |
| NORA, PF | 1 |
| TARKINGTON, JA | 1 |
| MEYER, NI | 1 |
| WATNE, AL | 3 |
| NADLER, S | 1 |
| ROSS, CA | 1 |
| AIMONE, V | 2 |
| KAJI, H | 1 |
| HUGHES, FJ | 1 |
| DYMARSKII, LIu | 1 |
| DILMAN, VM | 1 |
| ZALESSKAIA, LI | 1 |
| ZIV, MA | 1 |
| BOZNIBOV, EA | 1 |
| PAVLOVA, MV | 1 |
| ELHASSAN, AM | 1 |
| STUART, AE | 1 |
| KATCHMAN, BJ | 1 |
| ZIPF, RE | 1 |
| MURPHY, JP | 1 |
| IWATA, S | 1 |
| KAGEYAMA, T | 1 |
| HANO, S | 1 |
| ISHII, H | 1 |
| WAKABAYASHI, A | 1 |
| WADA, M | 1 |
| KURISU, T | 1 |
| FUJII, M | 1 |
| TSUTSUMI, T | 1 |
| ETALA, E | 1 |
| SOFIA, V | 1 |
| ROMERO, LM | 1 |
| BRINDLEY, CO | 1 |
| HODNETT, EM | 1 |
| KOCHETKOVA, VA | 1 |
| KOLIADIUK, IV | 1 |
| GOLUBEVA, IM | 1 |
| MASIK, MG | 1 |
| BARBA, EI | 1 |
| ZEZZANETO, L | 1 |
| SOERENSEN, B | 1 |
| SALIBA, AM | 1 |
| GRECCHI, R | 1 |
| HANKINS, GW | 1 |
| MCCARTEN, AB | 1 |
| SHAGIDULLIN, RS | 1 |
| GOLDENBERG, DM | 1 |
| COSTAKEL, O | 2 |
| FADEI, L | 1 |
| NACHTIGAL, M | 1 |
| NECHAEVA, ID | 2 |
| HIGGINS, GA | 1 |
| FLYNN, T | 1 |
| GILLESPIE, J | 1 |
| CUEVASHERNANDEZ, P | 1 |
| GENTIL, F | 2 |
| BRU, A | 1 |
| SHIMKIN, MB | 1 |
| VIANNA, JB | 1 |
| VIGI, F | 1 |
| PRAETORIUS, E | 1 |
| PLAUCHU, M | 1 |
| DALMAIS, J | 1 |
| GUINGAND, M | 1 |
| ARONOVITCH, M | 1 |
| GROSZMAN, M | 1 |
| KAHANA, LM | 1 |
| KREMENTZ, ET | 3 |
| KOKAME, GM | 1 |
| IGLESIAS, F | 1 |
| CREECH, O | 1 |
| ARIEL, IM | 1 |
| RESNICK, MI | 1 |
| GALEY, D | 1 |
| DWIGHT, RW | 1 |
| MARCHAND, P | 1 |
| PLESSISL, DU | 1 |
| BECKERLING, C | 1 |
| DURR, MH | 1 |
| POMMATAU, E | 1 |
| DARGENT, M | 1 |
| REVILLARD, JP | 1 |
| MOORE, JG | 1 |
| VANCAMPENHOUT, JL | 1 |
| BRANDKAMP, WW | 1 |
| SINCLAIR, WY | 1 |
| IRVINE, WT | 1 |
| EISMAN, SG | 1 |
| RICHARDSON, FM | 1 |
| SLOBODA, AE | 1 |
| VOGEL, AW | 1 |
| IMANAGA, H | 1 |
| IVANOVA, TT | 1 |
| SIGALOV, AB | 1 |
| SOROKA, PG | 1 |
| HILLER, SA | 1 |
| LIDAKS, MJ | 1 |
| ZIDERMANE, AA | 2 |
| GERMANE, SK | 1 |
| GRIGALINOVICH, GA | 2 |
| DAUVARTS, AZ | 1 |
| KRAVCHENKO, IM | 1 |
| PRESS, BO | 3 |
| HANDLER, AH | 1 |
| SARRIS, TG | 1 |
| WILLS, C | 1 |
| CHERNOV, VA | 3 |
| GRUSHINA, AA | 1 |
| SORKINA, YA | 1 |
| KONDO, T | 2 |
| COBB, JP | 1 |
| WALKER, DG | 2 |
| VERMEL, EM | 2 |
| KABAKOW, B | 1 |
| ALBAUM, H | 1 |
| ANTOPOL, W | 1 |
| BLINICK, G | 1 |
| SUSSMAN, L | 1 |
| GINZBURG, L | 1 |
| KUNDZINYA, I | 1 |
| TSEPLITT, R | 1 |
| POORKALN, T | 1 |
| AUZINYA, A | 1 |
| SKLAROFF, DM | 1 |
| BOURDIN, JS | 1 |
| SARACINO, RT | 1 |
| LILLE, I | 1 |
| GABAY, F | 1 |
| BELOVA, MG | 1 |
| VALUJEVA, IM | 1 |
| LEBRUN, J | 1 |
| SMETS, W | 1 |
| IONESCU, N | 1 |
| DRAGANESCU, C | 1 |
| PALAS, S | 1 |
| DEMETRIU, F | 1 |
| SVIATUKHINA, OV | 1 |
| PRIEDITE, IJ | 1 |
| DOWD, JE | 1 |
| DIPAOLO, JA | 1 |
| KADYROV, FA | 1 |
| HART, GD | 1 |
| BIANCHI, F | 1 |
| CAZZOLA, D | 1 |
| LAWTON, RL | 1 |
| HARPMAN, JA | 1 |
| HARMAN, JB | 1 |
| DONALDSON, SS | 1 |
| FLETCHER, WS | 1 |
| ZHAGATA, MA | 1 |
| PURKALNE, Ts | 1 |
| ZITARE, IIa | 1 |
| PRIEDITE, IIu | 1 |
| MELKS, EI | 1 |
| KAITMAZOVA-KHUDZHADZE, RG | 1 |
| TURBINA, IL | 2 |
| SEMENOV, NK | 1 |
| LAGARDE, C | 2 |
| HIRTZ, G | 1 |
| HUGUES, A | 2 |
| CHAUVERGNE, J | 2 |
| HOERNI, B | 1 |
| RUTMAN, RJ | 1 |
| BROWN, IS | 1 |
| ROSS, WM | 1 |
| WALDER, DN | 1 |
| VAKIL, VV | 1 |
| SIRSAT, MV | 1 |
| ZELENIK, JS | 1 |
| HALPERN, AJ | 1 |
| WILLIAMS, DW | 1 |
| GERICKE, D | 1 |
| BRONSHTEIN, BL | 1 |
| KHODZHAEV, VG | 1 |
| RUDDON, RW | 1 |
| MELLETT, LB | 1 |
| WRIGHT, JC | 1 |
| LYONS, MM | 1 |
| GOLOMB, FM | 1 |
| GUMPORT, SL | 1 |
| MEDREK, TJ | 1 |
| HRESCHCHYSHYN, MM | 1 |
| GREENSPAN, EM | 1 |
| KNOEPP, LF | 1 |
| LETSON, WM | 1 |
| DANNA, SJ | 1 |
| MOORE, JW | 1 |
| GRENVILLE-MATHERS, R | 1 |
| TRENCHARD, HJ | 1 |
| CHEEVER, AW | 1 |
| VALSAMIS, MP | 1 |
| RABSON, AS | 1 |
| WHEELER, GP | 1 |
| ALEXANDER, JA | 1 |
| ROGERS, LS | 1 |
| TSETLIN, AL | 1 |
| SAKURAI, Y | 1 |
| GOFFRINI, P | 1 |
| EDELSTYN, GA | 1 |
| CARLTON, HN | 1 |
| WHITLEY, R | 1 |
| GREKH, IF | 1 |
| KARLINSKAIA, RS | 1 |
| KURODA, K | 1 |
| HISAZUMI, H | 1 |
| WADA, I | 1 |
| SHIRAI, K | 1 |
| KIKUCHI, K | 1 |
| ANEHA, Y | 1 |
| YAMANAKA, M | 1 |
| TANEICHI, T | 1 |
| NATSUME, R | 1 |
| KANNO, H | 1 |
| NAGANUMA, H | 1 |
| SATO, Y | 1 |
| YOSHIZUMI, M | 1 |
| KUNII, Y | 1 |
| SATO, T | 1 |
| YAMAGATA, S | 1 |
| WATANABE, R | 1 |
| ESQUIVEL, EL | 1 |
| MACKENZIE, AR | 1 |
| WHITMORE, WF | 1 |
| GORDON, I | 1 |
| MCARTHUR, J | 1 |
| SUKHIN, GM | 2 |
| ABELL, MR | 1 |
| FAYOS, JV | 1 |
| LAMPE, I | 1 |
| BIRINGER, A | 1 |
| HOLAN, J | 1 |
| MEDLA, F | 1 |
| LACHAPELE, AP | 1 |
| LURE, AS | 1 |
| GOLDMAN, BS | 1 |
| PEARSON, FG | 1 |
| ROSENGERG, LM | 1 |
| POLANCO, GB | 1 |
| BLANK, S | 1 |
| GRAHNE, B | 1 |
| ROBERTS, SS | 1 |
| WEBB, RS | 1 |
| STREHL, FW | 1 |
| OATES, GD | 1 |
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| ROBERTS, DI | 1 |
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| Hillebrand, MJ | 1 |
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| Fiorentini, C | 1 |
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| Le Maitre, A | 1 |
| Grill, J | 1 |
| Drouard-Troalen, L | 1 |
| Paci, A | 1 |
| Benhamou, E | 1 |
| Rosman, IS | 1 |
| Lloyd, BM | 1 |
| Hayashi, RJ | 1 |
| Bayliss, SJ | 1 |
| Lytkin, GV | 1 |
| Korman, DB | 1 |
| Krutova, TV | 1 |
| Shamajev, VI | 1 |
| Shamberger, RC | 1 |
| Devereux, DF | 1 |
| Brennan, MF | 1 |
| Papaioannou, AN | 1 |
| Chang, Q | 1 |
| Hanks, S | 1 |
| Akard, L | 1 |
| Thompson, J | 1 |
| Harvey, K | 1 |
| English, D | 1 |
| Jansen, J | 1 |
| Dercksen, MW | 1 |
| Gerritsen, WR | 1 |
| Dirkson, MK | 1 |
| Slaper-Cortenbach, IC | 1 |
| Schaasberg, WP | 1 |
| Pinedo, HM | 2 |
| von dem Borne, AE | 1 |
| van der Schoot, CE | 1 |
| Weaver, CH | 3 |
| Hazelton, B | 1 |
| Birch, R | 1 |
| Palmer, P | 1 |
| Allen, C | 1 |
| Schwartzberg, L | 1 |
| West, W | 1 |
| van der Wall, E | 2 |
| ten Bokkel Huinink, WW | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intratumoral Cancer Chemotherapy Through a Flexible Bronchoscope as an Adjunct to Brachytherapy[NCT00379665] | Phase 2 | 25 participants (Actual) | Interventional | 2005-10-31 | Completed | ||
| A Prospective Randomized Feasibility and Phase II Adjuvant Breast Cancer Study of the Netherlands Working Party for Autotransplantation in Solid Tumors.[NCT00851110] | Phase 2 | 50 participants (Anticipated) | Interventional | 2004-10-31 | Terminated | ||
| Efficacy and Tolerance Adjuvant High-Dose Thiotepa With Peripheral Stem Cell Rescue Associated With Conventional Chemotherapy in Children and Adults With Relapsed Osteosarcoma[NCT00978471] | Phase 2 | 44 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 reviews available for thiotepa and Benign Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
[CHEMOTHERAPY BY PERFUSION FOR CANCER OF THE STOMACH AND COLON].
Topics: Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Flox | 1963 |
DRUGS USED WITH RADIATION IN THE TREATMENT OF CANCER.
Topics: Antineoplastic Agents; Chlortetracycline; Dactinomycin; DNA; DNA, Neoplasm; Fluorouracil; Humans; Me | 1963 |
SELECTION AND TREATMENT OF PATIENTS WITH ADVANCED BREAST CANCER.
Topics: Adrenalectomy; Androgens; Breast; Breast Neoplasms; Cortisone; Estrogens; Female; Humans; Hypophysec | 1964 |
Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa.
Topics: Antineoplastic Agents, Alkylating; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Ins | 2004 |
The effect of chemotherapeutic agents on wound healing.
Topics: Adrenal Cortex Hormones; Anemia; Animals; Antineoplastic Agents; Azathioprine; Collagen; Cyclophosph | 1981 |
Preoperative chemotherapy for operable solid tumours.
Topics: Adult; Animals; Antineoplastic Agents; Child; Cyclophosphamide; Female; Humans; Immunosuppression Th | 1981 |
Pharmacokinetics of alkylating agents.
Topics: Alkylating Agents; Carmustine; Chlorambucil; Cyclophosphamide; Humans; Ifosfamide; Lomustine; Melpha | 1993 |
Peripheral blood progenitor cell transplantation: a single centre experience comparing two mobilisation regimens in 67 patients.
Topics: Adolescent; Adult; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmust | 1996 |
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinom | 1976 |
Tris (1-aziridinyl)phosphine sulphide.
Topics: Animals; Carcinogens; Drosophila melanogaster; Drug Evaluation, Preclinical; Female; Genes, Lethal; | 1975 |
High-dose N,N',N"-triethylenethiophosphoramide (thiotepa) with autologous bone marrow transplantation: phase I studies.
Topics: Bone Marrow Transplantation; Combined Modality Therapy; Drug Evaluation; Humans; Neoplasms; Thiotepa | 1990 |
Solid tumor chemotherapy: What have we to offer.
Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Huma | 1970 |
[On ways of reducing the toxic effects of antitumorous preparations].
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Animals; Antineoplastic Agents; beta-Aminoethyl Isot | 1968 |
Chemotherapy of residual disease in solid tumours.
Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun | 1971 |
[Use of optical quantum generators (lasers) in oncology].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Basal Cell; Carcinom | 1972 |
Free radicals and neoplasia--some experimental findings and some possible implications.
Topics: Adenofibroma; Animals; Breast Neoplasms; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Carcinoma | 1972 |
Cancer chemotherapy. I.
Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechlorethamine; Melphalan; | 1972 |
[Combination chemotherapy in the treatment of cancer].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Dacti | 1972 |
[Modern drugs for the treatment of cancer].
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Neoplasms; Phosphines; Piperazines; Thiot | 1966 |
Multiple combination therapy in cancer chemotherapy in Japan.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug | 1969 |
[Regional perfusion therapy of malignant tumors of the extremities].
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regi | 1970 |
[Side-effects of cytostatic therapy with special reference to potential carcinogenic effects].
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bus | 1971 |
[Alkylating cytostatic agents].
Topics: Alkylating Agents; Alkylation; Animals; Busulfan; Cell Division; Chemical Phenomena; Chemistry; Chlo | 1971 |
28 trials available for thiotepa and Benign Neoplasms
| Article | Year |
|---|---|
Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin.
Topics: Adolescent; Adult; Carboplatin; Cyclophosphamide; Female; Gene Frequency; Genotype; Humans; Inactiva | 2008 |
In children and adolescents, the pharmacodynamics of high-dose busulfan is dependent on the second alkylating agent used in the combined regimen (melphalan or thiotepa).
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols | 2003 |
Long-term results of intrapericardial chemotherapeutic treatment of malignant pericardial effusions with thiotepa.
Topics: Antineoplastic Agents, Alkylating; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Ins | 2004 |
Accuracy, feasibility, and clinical impact of prospective Bayesian pharmacokinetically guided dosing of cyclophosphamide, thiotepa, and carboplatin in high-dose chemotherapy.
Topics: Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bay | 2005 |
Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.
Topics: Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bre | 2005 |
Elevated plasma ferritin and busulfan pharmacodynamics during high-dose chemotherapy regimens in children with malignant solid tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Cyclo | 2007 |
Maturation of mobilized peripheral blood progenitor cells: preclinical and phase I clinical studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cell Differentiation; | 1995 |
An analysis of engraftment kinetics as a function of the CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cell | 1995 |
Pilot study of a high-dose carboplatin-based salvage strategy for relapsing or refractory germ cell cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Com | 1995 |
A pilot clinical and pharmacological study of intra-arterial infusion of thiotepa.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intra-Arterial; N | 1993 |
Phase I study of high-dose busulfan, melphalan and thiotepa with autologous stem cell support in patients with refractory malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Busulfan; Combi | 1994 |
Thiotepa, busulfan, and cyclophosphamide as a preparative regimen for marrow transplantation: risk factors for early regimen-related toxicity.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Hematologic Diseases; Humans | 1994 |
Calvert's formula and high-dose carboplatin.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Combined Modality The | 1994 |
A phase I/II study of high-dose cyclophosphamide, cisplatin, and thioTEPA followed by autologous bone marrow and granulocyte colony-stimulating factor-primed peripheral-blood progenitor cells in patients with advanced malignancies.
Topics: Adult; Bone Marrow Transplantation; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dose-Res | 1996 |
Urinary elimination of cyclophosphamide alkylating metabolites and free thiols following two administration schedules of high-dose cyclophosphamide and mesna.
Topics: Adult; Antineoplastic Agents, Alkylating; Carboplatin; Cyclophosphamide; Cystitis; Drug Administrati | 1996 |
Peripheral blood progenitor cell transplantation: a single centre experience comparing two mobilisation regimens in 67 patients.
Topics: Adolescent; Adult; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmust | 1996 |
Phase II study of high-dose busulfan, melphalan and thiotepa with autologous peripheral blood stem cell support in patients with malignant disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Busulfan; | 1996 |
A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Humans; Neoplasms; Neuroectode | 1996 |
High-dose sequential chemotherapy and autologous stem cell reinfusion in advanced pediatric solid tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; | 1997 |
Phase II study of high-dose thiotepa and hematopoietic stem cell transplantation in children with solid tumors.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Child; Child, Preschool; Combined Modali | 1998 |
A phase I dose escalation study of high-dose thiotepa, melphalan and carboplatin (TMCb) followed by autologous peripheral blood stem cell transplantation (PBSCT) in patients with solid tumors and hematologic malignancies.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Dose- | 2000 |
Treatment of malignant meningeal disease with intrathecal thioTEPA: a phase II study.
Topics: Clinical Trials as Topic; Drug Evaluation; Hematologic Diseases; Humans; Injections, Spinal; Meninge | 1977 |
Mepacrine hydrochloride in the treatment of malignant pleural effusion. A controlled randomized trial.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neoplasms; Pleura; Pleural | 1977 |
Feasibility and toxicity study of a high-dose chemotherapy regimen for autotransplantation incorporating carboplatin, cyclophosphamide and thiotepa.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Com | 1992 |
Phase I trial of thiotepa in combination with recombinant human granulocyte-macrophage colony-stimulating factor.
Topics: Aged; Drug Administration Schedule; Drug Evaluation; Female; Granulocyte-Macrophage Colony-Stimulati | 1992 |
Phase I/pharmacokinetic reevaluation of thioTEPA.
Topics: Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Leukocyte Count; Leukopenia; Male | 1991 |
Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Drug Tolerance; Ethacr | 1991 |
A phase I-II study of high-dose cyclophosphamide, thiotepa and escalating doses of mitoxantrone with autologous stem cell rescue in patients with refractory malignancies.
Topics: Actuarial Analysis; Chicago; Cyclophosphamide; Drug Evaluation; Heart Failure; Hematopoietic Stem Ce | 1990 |
248 other studies available for thiotepa and Benign Neoplasms
| Article | Year |
|---|---|
Thiotepa-busulfan-fludarabine (TBF) conditioning regimen in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis: an outcome analysis from the Chronic Malignancies Working Party of the EBMT.
Topics: Busulfan; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Neopl | 2021 |
High-dose thiotepa-related neurotoxicity and the role of tramadol in children.
Topics: Adolescent; Analgesics, Opioid; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother | 2018 |
Salvage Treatment with Intracerebrospinal Fluid Thiotepa in Patients with Leptomeningeal Metastasis After Failure of Methotrexate-based Treatment.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Female; Follow-Up S | 2015 |
Psychosexual development and satisfaction in long-term survivors of childhood cancer: Neurotoxic treatment intensity as a risk indicator.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cranial Irradiation; Cytarabine | 2017 |
Advancing personalized cancer therapy by detection and characterization of circulating carcinoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Carboplatin; Chromoso | 2010 |
Thiotepa.
Topics: Animals; Antineoplastic Agents, Alkylating; Carcinogens; Chemosterilants; Female; Neoplasms; Thiotep | 2011 |
Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.
Topics: Adolescent; Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carbo | 2002 |
Palliation of far-advanced cancer with triethylene thiophosphoramide.
Topics: Humans; Neoplasms; Palliative Care; Phosphorus; Phosphorus, Dietary; Thiotepa | 1955 |
Treatment of Hodgkin's granuloma, chronic lymphatic leukaemia, polycythaemia vera, and other reticuloses with triethylenethiophosphoramide.
Topics: Antineoplastic Agents; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Ce | 1956 |
Treatment of Hodgkin's granuloma, chronic lymphatic leukaemia, polycythaemia vera, and other reticuloses with triethylenethiophosphoramide.
Topics: Antineoplastic Agents; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Ce | 1956 |
Treatment of Hodgkin's granuloma, chronic lymphatic leukaemia, polycythaemia vera, and other reticuloses with triethylenethiophosphoramide.
Topics: Antineoplastic Agents; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Ce | 1956 |
Treatment of Hodgkin's granuloma, chronic lymphatic leukaemia, polycythaemia vera, and other reticuloses with triethylenethiophosphoramide.
Topics: Antineoplastic Agents; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Ce | 1956 |
[Triethylenethiophosphoramide in the treatment of the osteosarcoma and lymphomatosis].
Topics: Antineoplastic Agents; Bone Neoplasms; Humans; Lymphoma; Neoplasms; Osteosarcoma; Thiotepa | 1956 |
The prophylactic treatment of malignant disease with nitrogen mustard and triethylenethiophosphoramide (thio-TEPA).
Topics: Antineoplastic Agents; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Thiotepa | 1957 |
The experimental design of studies to evaluate the chemotherapy of solid tumors as demonstrated by the use of triethylenethiophosphoramide.
Topics: Antineoplastic Agents; Humans; Neoplasms; Research Design; Thiotepa | 1957 |
The use of thio-tepa (triethylene thiophosphoramide) in melanotic sarcoma.
Topics: Antineoplastic Agents; Humans; Melanoma; Neoplasms; Sarcoma; Thiotepa | 1957 |
Use of triethylene thiophosphoramide (thio-TEPA) in treatment of advanced cancer.
Topics: Antineoplastic Agents; Neoplasms; Thiotepa | 1957 |
Triethylenethiophosphoramide.
Topics: Antineoplastic Agents; Humans; Neoplasms; Thiotepa | 1957 |
Experience with triethylene melamine (TEM) and triethylene thiophosphoramide (thioTEPA) in recurrent or metastatic solid tumors.
Topics: Antineoplastic Agents; Neoplasms; Thiotepa; Triethylenemelamine | 1958 |
The changes in the serum proteins and lipoproteins of patients in remission from ovarian carcinoma during treatment with thiotepa.
Topics: Blood Proteins; Female; Humans; Lipoproteins; Neoplasms; Ovarian Neoplasms; Ovary; Thiotepa | 1957 |
Triethylenethiophosphoramide in treatment of metastatic cerebral malignancy.
Topics: Antineoplastic Agents; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Diagnosis, Differential; | 1958 |
[Cytotoxic drugs and malignant tumors; action of triethylene melamine, of diethylene-dipropryloxy-benzoquinone and of thiophosphoramide].
Topics: Antineoplastic Agents; Benzoquinones; Neoplasms; Thiotepa; Triethylenemelamine | 1958 |
Chlorambucil and triethylene thiophosphoramide in the treatment of neoplastic disease.
Topics: Antineoplastic Agents; Chlorambucil; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; | 1958 |
The treatment of advanced cancer with triethylene thiophosphoramide.
Topics: Antineoplastic Agents; Neoplasms; Thiotepa | 1958 |
Palliation of cancer in human patients by maintenance therapy with NN'N"-triethylene thiophosphoramide and N-(3-oxapentamethylene)-N'N"-diethylene phosphoramide.
Topics: Antineoplastic Agents; Humans; Neoplasms; Palliative Care; Phosphoramides; Thiotepa | 1958 |
Experimental and clinical experience with thio-TEPA in leukemia and inoperable cancer.
Topics: Antineoplastic Agents; Leukemia; Neoplasms; Thiotepa | 1958 |
Clinical studies of triethylene thiophosphoramide in the treatment of advanced neoplastic disease.
Topics: Antineoplastic Agents; Biomedical Research; Neoplasms; Thiotepa | 1958 |
Oxapentamethylenediethylene thiophosphoramide (OPSPA) in the treatment of human cancer.
Topics: Antineoplastic Agents; Neoplasms; Thiotepa | 1958 |
[Triethylene-phosphoramide or thio-TEPA in therapy of recurrent cancer of the breast].
Topics: Antineoplastic Agents; Breast; Breast Neoplasms; Humans; Neoplasm Recurrence, Local; Neoplasms; Phos | 1959 |
[Triethylenethiophosphoramide in the therapy of malignant neoplasms].
Topics: Antineoplastic Agents; Humans; Neoplasms; Thiotepa | 1959 |
[Nitrogen mustards, triethylenethiophosphoramide, triethylene melamine & aminopterin in the treatment of advanced cancer].
Topics: Aminopterin; Antineoplastic Agents; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Thiotepa | 1959 |
The cytological effect of chemicals on tumors. XI. Effects of thio-TEPA and actinomycin-C on normal and neoplastic cells in vitro.
Topics: Antineoplastic Agents; Dactinomycin; Humans; In Vitro Techniques; Neoplasms; Thiotepa | 1961 |
[Experience in the use of the preparation thioTEPA in various diseases in children].
Topics: Antineoplastic Agents; Child; Hodgkin Disease; Humans; Infant; Lymphoma, Large B-Cell, Diffuse; Lymp | 1961 |
Response of a spectrum of transplanted rat neoplasms to urethane, thioTEPA, and two "dual antagonists".
Topics: Animals; Antineoplastic Agents; Neoplasm Transplantation; Neoplasms; Rats; Thiotepa; Urethane | 1961 |
Effect of thio TEPA on the synthesis of protein and nucleic acids in tumor-bearing mice.
Topics: Animals; Antineoplastic Agents; Mice; Neoplasms; Nucleic Acids; Proteins; Thiotepa | 1961 |
[Immediate results of Thio-TEPA therapy of patients with cancer of the female genitalia].
Topics: Antineoplastic Agents; Female; Genitalia; Genitalia, Female; Humans; Neoplasms; Thiotepa | 1961 |
[Use of Thio-TEPA in advanced malignant tumors of the ovaries].
Topics: Antineoplastic Agents; Female; Humans; Neoplasms; Ovarian Neoplasms; Thiotepa | 1961 |
Thio-tepa and related agents in the management of far advanced cancer.
Topics: Antineoplastic Agents; Disease Management; Female; Humans; Neoplasms; Thiotepa | 1961 |
[The chemotherapy of malignant tumors of the ovary with thio-TEPA].
Topics: Antineoplastic Agents; Female; Humans; Neoplasms; Ovarian Neoplasms; Thiotepa | 1960 |
Thiotepa in the treatment of tumours of the bladder.
Topics: Antineoplastic Agents; Humans; Neoplasms; Thiotepa; Urinary Bladder Neoplasms | 1961 |
Gastrointestinal cancer: palliation of advanced cancer of the gastrointestinal tract with N,N',N" triethylene thiophosphoramide.
Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Tract; Humans; Neoplasms; Pallia | 1959 |
Clinical experience with triethylenethiophosphoramide (Thio-TEPA) in the treatment of cancer.
Topics: Antineoplastic Agents; Neoplasms; Thiotepa | 1960 |
Effect of Thio-TEPA on advanced malignant ovarian tumours.
Topics: Antineoplastic Agents; Female; Humans; Neoplasms; Ovarian Neoplasms; Thiotepa | 1960 |
[Thio-tepa in 45 cases of malignant tumors].
Topics: Antineoplastic Agents; Neoplasms; Thiotepa | 1959 |
Thiotepa in treatment of advanced breast cancer.
Topics: Breast; Breast Neoplasms; Humans; Neoplasms; Thiotepa | 1962 |
Intraarterial chemotherapy and x-ray therapy in cancer of the head and neck. Technique, methods, results and complications.
Topics: Head; Head and Neck Neoplasms; Humans; Mechlorethamine; Methotrexate; Neck; Neoplasms; Thiotepa; X-R | 1963 |
Influences of anticancer agents on the activities of liver catalase, uricase, and xanthine oxidase in normal and tumor-bearing mice.
Topics: Aminopterin; Animals; Antineoplastic Agents; Azaguanine; Carboxylic Acids; Carcinoma, Ehrlich Tumor; | 1963 |
The chemotherapy of intrathoracic tumors.
Topics: Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Humans; Mechlorethamine; Methotrexate; Neopl | 1962 |
Chemotherapy of malignant disease. I. Solid tumours.
Topics: Cyclophosphamide; Dactinomycin; Fluorouracil; Mechlorethamine; Methotrexate; Mitomycin; Mitomycins; | 1962 |
Cancer chemotherapy by intra-arterial infusion.
Topics: Dactinomycin; Fluorouracil; Humans; Infusions, Intra-Arterial; Mechlorethamine; Methotrexate; Neopla | 1963 |
Preoperative anticancer chemotherapy. Preliminary report.
Topics: Antineoplastic Agents; Fluorouracil; Neoplasms; Surgical Procedures, Operative; Thiotepa | 1962 |
[On the subject of medical therapy of gynecological tumors].
Topics: Aziridines; Cyclophosphamide; Female; Genital Neoplasms, Female; Humans; Neoplasms; Thiotepa | 1963 |
[On the subject of medical therapy of tumors in gynecology. I].
Topics: Aziridines; Cyclophosphamide; Female; Genital Neoplasms, Female; Gynecology; Humans; Neoplasms; Thio | 1963 |
[Electrophoretic studies on serum and tissue protein of the liver and the tumor in the malignant tumor bearing bodies. II. Electrophoretic studies on tissue protein of liver and the tumor of malignant tumor-bearing bodies and the influences of irradiation
Topics: Carbon Tetrachloride; Cobalt Isotopes; Female; Humans; Liver; Neoplasm Proteins; Neoplasms; Neoplasm | 1962 |
REGIONAL PERFUSION CHEMOTHERAPY OF ADVANCED CANCER.
Topics: Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Fluorouracil; Hypothermia; Hypothermia, Indu | 1963 |
HORMONAL THERAPY OF CANCER.
Topics: Adrenal Cortex Hormones; Androgens; Antineoplastic Agents; Breast Neoplasms; Estradiol; Estrogens; H | 1963 |
[COMBINED HORMONE-CHEMOTHERAPY AND RADIOTHERAPY OF PATIENTS WITH FAR ADVANCED BREAST CANCER].
Topics: Adrenal Cortex Hormones; Androgens; Breast Neoplasms; Castration; Female; Humans; Neoplasms; Ovary; | 1963 |
INHIBITION AND ENHANCEMENT OF MOUSE ASCITES TUMOR AFTER TREATMENT WITH LIVING LYMPHOID CELLS.
Topics: Allergy and Immunology; Animals; Ascites; Lymphocytes; Mice; Neoplasms; Neoplasms, Experimental; Res | 1963 |
THE EFFECT OF CHEMOTHERAPEUTIC AGENTS UPON THE METABOLISM OF INTACT HUMAN CANCER CELLS: AN IN VITRO TECHNIC FOR CELL SENSITIVITY.
Topics: Aminopterin; Antineoplastic Agents; Azaguanine; Carbohydrate Metabolism; In Vitro Techniques; Lactat | 1963 |
[CLINICAL AND EXPERIMENTAL STUDIES ON CHANGES IN THE BODY FLUIDS IN CANCER].
Topics: Antineoplastic Agents; Arginine; Ascites; Aspartate Aminotransferases; Blood Chemical Analysis; Bloo | 1963 |
METHODOLOGY OF PRELIMINARY CHEMOTHERAPEUTIC TRIALS IN PATIENTS WITH MALIGNANT SOLID TUMORS.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Colonic Neoplasms; Cyclophosp | 1963 |
[INTERRELATIONSHIP BETWEEN SOME ANTINEOPLASTIC CHEMOTHERAPEUTIC PREPARATIONS AND ANTIBIOTICS FOLLOWING THEIR SIMULTANEOUS ADMINISTRATION IN CANCER PATIENTS].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Blood Chemical Analysis; | 1963 |
[COMPARATIVE EVALUATION OF THE EFFECTIVENESS OF SOME METHODS OF TREATING LYMPHOGRANULOMATOSIS].
Topics: Hodgkin Disease; Neoplasms; Thiotepa | 1963 |
[TEST OF THE ACTION OF SOME NITROGEN MUSTARD DERIVATIVES ON STICKER'S LYMPHOSARCOMA].
Topics: Animals; Cyclophosphamide; Dogs; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Neopla | 1963 |
ADJUVANT CHEMOTHERAPY (TRIETHYLENE THIOPHOSPHORAMIDE) WITH RADICAL MASTECTOMY AND RADIOTHERAPY IN BREAST CANCER.
Topics: Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Humans; Leukopenia; Mastectomy; Mastectomy, Rad | 1963 |
[USE OF CALCIUM SALTS, VITAMIN D2 AND FISH OIL DURING THIO-TEPA THERAPY OF PATIENTS WITH LUNG CANCER AND LYMPHOGRANULOMATOSIS].
Topics: Calcium; Ergocalciferols; Fish Oils; Hodgkin Disease; Lung Neoplasms; Neoplasms; Salts; Thiotepa | 1963 |
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchic | 1963 |
SCREENING TEST FOR CYTOTOXIC AGENTS ON TUMOR PRIMARY CELL CULTURES.
Topics: Antineoplastic Agents; Cricetinae; Cytotoxins; Neoplasms; Pharmacology; Primary Cell Culture; Resear | 1963 |
[COMPARATIVE EVALUATION OF METHODS OF TREATING PATIENTS WITH FAR ADVANCED MALIGNANT OVARIAN NEOPLASMS].
Topics: Female; Humans; Neoplasms; Ovarian Neoplasms; Surgical Procedures, Operative; Thiotepa | 1963 |
EFFECT OF SPLENECTOMY ON TOLERANCE TO THIO-TEPA.
Topics: Colonic Neoplasms; Dogs; Drug Tolerance; Gastrectomy; Mortality; Neoplasms; Splenectomy; Stomach Neo | 1964 |
[METASTATIC CARCINOMA OF THE MAMMARY GLAND TREATED WITH TRIETHYLENOTHIOPHOSPHORAMIDE. STUDY OF 10 PATIENTS].
Topics: Breast Neoplasms; Carcinoma; Geriatrics; Humans; Mammary Glands, Human; Neoplasm Metastasis; Neoplas | 1963 |
[CHEMOTHERAPY OF CANCER OF THE OVARY].
Topics: Androgens; Castration; Chlorambucil; Cobalt Isotopes; Corpus Luteum Hormones; Female; Humans; Neopla | 1963 |
[APROPOS OF THE RESPECTIVE INDICATIONS OF RADIOACTIVE COLLOIDS AND ANTIMITOTICS IN THE TREATMENT OF CARCINOSIS OF THE SEROUS MEMBRANES].
Topics: Antimitotic Agents; Ascites; Colloids; Exudates and Transudates; Humans; Neoplasms; Phosphorus Isoto | 1963 |
THE NUMERICAL METHOD IN THERAPEUTIC MEDICINE.
Topics: Biometry; Breast Neoplasms; Connecticut; France; History; History, 19th Century; History, 20th Centu | 1964 |
CHEMOTHERAPY ON THE CANCER TEAM.
Topics: Antineoplastic Agents; Geriatrics; Neoplasms; Thiotepa | 1964 |
[TREATMENT OF CANCER OF THE BLADDER].
Topics: Cystoscopy; Mechlorethamine; Neoplasms; Pathology; Surgical Procedures, Operative; Thiotepa; Urinary | 1963 |
[CURRENT PRACTICE IN THE TREATMENT OF TUMORS WITH INTRA-ARTERIAL INJECTIONS OF ANTINEOPLASTIC SUBSTANCES].
Topics: Aminopterin; Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Chlorambuci | 1963 |
[SURVIVAL TIME AND ABILITY TO WORK IN HEMOBLASTOSES TREATED BY CHEMOTHERAPY].
Topics: Antineoplastic Agents; Aziridines; Biomedical Research; Cyclophosphamide; Genetic Diseases, X-Linked | 1963 |
[MEDULLARY APLASIA DURING THE USE OF 4 ANTIMITOTICS: CARYOLYSIN, MYLERAN, THIOTEPA, ENDOXAN (APROPOS OF 32 CASES)].
Topics: Anemia; Anemia, Aplastic; Antimitotic Agents; Busulfan; Cyclophosphamide; Neoplasms; Nitrogen Mustar | 1963 |
SOME PROBLEMS IN THE CHEMOTHERAPY OF SOLID TUMOURS.
Topics: Breast Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Mechlorethamine; Neoplasms; Thiotepa; Toxi | 1964 |
CURRENT STATUS OF CHEMOTHERAPY OF CANCER.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Black People; Chemotherapy, Cancer, | 1964 |
REGIONAL PERFUSION IN MELANOMA OF LIMBS.
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Mechlorethamin | 1964 |
THE INTRALYMPHATIC ADMINISTRATION OF RADIOACTIVE ISOTOPES AND CANCER CHEMOTHERAPEUTIC DRUGS.
Topics: Abdominal Neoplasms; Angiography; Breast Neoplasms; Geriatrics; Gold; Humans; Injections; Iodine Iso | 1964 |
ADJUVANT CHEMOTHERAPY IN CANCER OF THE LARGE BOWEL. AN INTERIM REPORT OF THE VETERANS ADMINISTRATION SURGICAL ADJUVANT CANCER CHEMOTHERAPY STUDY.
Topics: Adenocarcinoma; Chemotherapy, Adjuvant; Colonic Neoplasms; Geriatrics; Neoplasms; Postoperative Comp | 1964 |
EXTRACORPOREAL HYPOTHERMIA WITHOUT THORACOTOMY. AN EXPERIMENTAL STUDY IN THE USE OF COLD FOR NEUROSURGERY AND CANCERICIDAL PERFUSIONS.
Topics: Blood Flow Velocity; Body Temperature; Cardiac Surgical Procedures; Chemotherapy, Cancer, Regional P | 1964 |
[TRIETHYLENE THIO-PHOSPHORAMIDE (THIO-TEPA) IN THE TREATMENT OF MALIGNANT TUMORS].
Topics: Breast Neoplasms; Female; Humans; Melanoma; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Phosp | 1964 |
EFFECTS OF IONIZING IRRADIATION AND CHEMOTHERAPEUTIC AGENTS ON HUMAN CHROMOSOMES.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Choriocarcinoma; Chromosome Aberrations; C | 1964 |
SOME OBSERVATIONS ON THE CHEMOTHERAPEUTIC PALLIATION OF INOPERABLE PRIMARY CARCINOMA OF THE OVARY USING TRIETHYLENE THIOPHOSPHORAMIDE.
Topics: Carcinoma; Cystadenocarcinoma; Female; Humans; Neoplasms; Ovarian Neoplasms; Palliative Care; Surgic | 1964 |
CANCER CHEMOTHERAPY.
Topics: Adrenal Cortex Hormones; Aminopterin; Androgens; Antimetabolites; Antineoplastic Agents; Blood Plate | 1964 |
A LABORATORY EVALUATION OF 1,4-DIMETHYL-1,4-DIPHENYL-2-TETRAZENE (CENTRAZENE), A CARCINOSTATIC COMPOUND.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Carcinoma 256, Walker; Lymphoma, Non-Hodgkin; Ma | 1964 |
[PREVENTION OF THE RECURRENCE OF CANCER].
Topics: Animals; Biomedical Research; Genetic Diseases, X-Linked; Hormones; Leukemia, Hairy Cell; Lymphatic | 1964 |
[CHRONIC LYMPHADENOSIS AND CANCER OF THE ESOPHAGUS].
Topics: Esophageal Neoplasms; Esophagus; Lymphadenitis; Neoplasms; Pathology; Thiotepa; Toxicology | 1963 |
[THIO-TEPA THERAPY OF PATIENTS WITH FAR ADVANCED MALIGNANT TUMORS OF THE OVARY].
Topics: Female; Humans; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Thiotepa | 1963 |
FURTHER STUDIES ON THE EFFECT OF THIOTEPA ON THE SYNTHESIS OF PROTEIN AND NUCLEIC ACIDS IN TUMOR-BEARING MICE.
Topics: Animals; DNA; DNA, Neoplasm; Glycine; Lymphoma, Non-Hodgkin; Metabolism; Mice; Neoplasm Proteins; Ne | 1964 |
ANTITUMOROUS SUBSTANCES WITH RADIOMIMETIC AND RADIOPROTECTIVE GROUPS.
Topics: Acetylcholine; Antineoplastic Agents; Blood Pressure; Carcinoma 256, Walker; Cats; Erythropoiesis; L | 1964 |
CHEMOTHERAPY STUDIES ON PRIMARY TUMOR GRAFTS AND METASTASES IN HAMSTERS AND MICE.
Topics: Antineoplastic Agents; Cricetinae; Cyclophosphamide; Dactinomycin; Melphalan; Mice; Mitomycin; Mitom | 1964 |
THE EFFECT PRODUCED BY SOME HORMONES ON THE ANTITUMOUR ACTIVITY OF ETHYLENIMINE AND BETA-CHLORETHYLAMINE DERIVATIVES.
Topics: Adrenocorticotropic Hormone; Antineoplastic Agents; Aziridines; Cortisone; Growth Hormone; Neoplasms | 1964 |
THE ADVERSE EFFECTS OF CANCER CHEMOTHERAPY.
Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma, Ehrlich Tumor; Cortisone; Cyclophosphamide; D | 1964 |
STUDIES ON HUMAN MELANOMA CELLS IN TISSUE CULTURE. II. EFFECTS OF SEVERAL CANCER CHEMOTHERAPEUTIC AGENTS ON CYTOLOGY AND GROWTH.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Chlorambucil; Dactinomycin; Fluorouracil; Melanoma; Me | 1964 |
THE SEARCH FOR ANTITUMOUR SUBSTANCES OF PLANT ORIGIN.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Gossypol; Melanoma; Mice; Neopl | 1964 |
SERIAL ENZYME CHANGES IN CANCER PATIENTS UNDERGOING CHEMOTHERAPY.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Enzyme Tests; Colonic Neoplasms; D-Alani | 1964 |
(OUR EXPERIENCE IN USING THIOTEPA IN ONCOLOGICAL HOSPITALS.)
Topics: Breast Neoplasms; Female; Hodgkin Disease; Humans; Latvia; Lung Neoplasms; Neoplasms; Ovarian Neopla | 1964 |
CLINICAL EXPERIENCE WITH CHEMOTHERAPY AND COBALT IRRADIATION IN THE TREATMENT OF ADVANCED CANCER.
Topics: Cobalt; Cobalt Isotopes; Female; Gastrointestinal Neoplasms; Humans; Neoplasms; Ovarian Neoplasms; T | 1964 |
[STUDY OF VARIATIONS IN THE COMPLEMENT LEVEL IN THE COURSE OF CANCER CHEMOTHERAPY].
Topics: Animals; Breast Neoplasms; Bronchial Neoplasms; Complement System Proteins; Cyclophosphamide; Dexame | 1964 |
MORPHOLOGICAL CHANGES IN HUMAN TUMOURS TREATED BY THIO-TEPA.
Topics: Breast Neoplasms; Female; Humans; Necrosis; Neoplasms; Thiotepa; Uterine Neoplasms | 1964 |
INFLUENCE OF BOTH HORMONAL AND ALKYLATING DRUGS ON FOLLICLE-STIMULATION FUNCTION OF THE PITUITARY.
Topics: Breast Neoplasms; Dysgerminoma; Female; Follicle Stimulating Hormone; Hexestrol; Humans; Melphalan; | 1964 |
[REGIONAL PERFUSION BY EXTRACORPOREAL CIRCULATION. INITIAL RESULTS].
Topics: Chemotherapy, Cancer, Regional Perfusion; Heart, Artificial; Mechlorethamine; Melphalan; Neoplasms; | 1964 |
CHEMOTHERAPY ASSOCIATED TO SURGERY IN THE TREATMENT OF CANCER OF THE BREAST AND OVARY.
Topics: Aziridines; Breast Neoplasms; Cyclophosphamide; Female; Humans; Melphalan; Neoplasms; Ovarian Neopla | 1964 |
HORMONE THERAPY OF PATIENTS WITH ADVANCED CANCER OF THE BREAST.
Topics: Bone Neoplasms; Breast Neoplasms; Castration; Cortisone; Estrogens; Female; Follicle Stimulating Hor | 1964 |
COMPLEX TREATMENT APPLIED IN CASES OF NEGLECTED CANCER OF THE MAMMARY GLAND.
Topics: Bone Neoplasms; Breast Neoplasms; Castration; Cortisone; Female; Humans; Mammary Glands, Human; Meth | 1964 |
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neopla | 1964 |
IV. COMBINATION OF CHEMOTHERAPY AND SURGERY IN THE TREATMENT OF CANCER. INTRA-ARTERIAL CANCER CHEMOTHERAPY WITH OR WITHOUT AN ISOLATED EXTRACORPOREAL CIRCUIT.
Topics: Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Humans; Infusions, Parenteral; Injection | 1964 |
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neop | 1964 |
[RETICULOSARCOMA OF THE STOMACH].
Topics: Drug Therapy; Gastrectomy; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Pathol | 1964 |
PALLIATIVE MANAGEMENT OF GASTROINTESTINAL CANCER.
Topics: Adenocarcinoma; Ascites; Deglutition Disorders; Fluorouracil; Humans; Neoplasm Metastasis; Neoplasms | 1964 |
[ANTITUMOR CHEMOTHERAPY IN THE TREATMENT OF MALIGNANT NEOPLASMS OF THE OVARY].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Carcinoma; Cyclophosphamide; Female; Humans; Methotrexate; | 1964 |
JET INJECTION OF DRUGS INTO MALIGNANT NEOPLASMS.
Topics: Breast Neoplasms; Drug Therapy; Equipment and Supplies; Humans; Injections; Injections, Jet; Melanom | 1964 |
ON BLOCK DISSECTION OF THE NECK.
Topics: Adrenal Cortex Hormones; Carotid Arteries; Esophageal Neoplasms; Humans; Laryngeal Neoplasms; Lympha | 1964 |
THE TREATMENT OF INCURABLE MALIGNANT DISEASE.
Topics: Adrenalectomy; Androgens; Breast Neoplasms; Busulfan; Chlorambucil; Estrogens; Heroin; Hormones; Hum | 1964 |
THE TREATMENT OF CANCER BY ISOLATION PERFUSION.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Chemotherapy, Canc | 1964 |
[CYCLOPHOSPHANE, ETHOXENE AND THIO-TEPA IN THE PREVENTION OF METASTASES FOLLOWING SURGICAL EXTIRPATION OF TRANSPLANTED TUMORS].
Topics: Antineoplastic Agents; Cyclophosphamide; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimenta | 1963 |
[APROPOS OF MORPHOLOGICAL CHANGES IN HUMAN CANCEROUS TUMORS DURING THIO-TEPA THERAPY. I].
Topics: Breast Neoplasms; Drug Therapy; Female; Humans; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; P | 1963 |
[USE OF THIOTEPA IN COMBINED THERAPY OF BREAST CANCER].
Topics: Breast Neoplasms; Drug Therapy; Hormones; Humans; Mastectomy; Neoplasms; Thiotepa | 1963 |
[CYTOLOGICAL PICTURE OF CANCER EXUDATES (CLINICAL OBSERVATIONS DURING THE COURSE OF CHEMOTHERAPY)].
Topics: Antineoplastic Agents; Ascites; Cytodiagnosis; Exudates and Transudates; Humans; Neoplasms; Thiotepa | 1963 |
[COMBINED THERAPY OF NEGLECTED CASES OF BREAST CANCER].
Topics: Breast Neoplasms; Cortisone; Drug Therapy; Humans; Methyltestosterone; Neoplasms; Pituitary Irradiat | 1963 |
[EFFECTIVENESS OF THIO-TEPA IN CANCER OF THE FEMALE GENITALIA (PRELIMINARY COMMUNICATION)].
Topics: Communication; Drug Therapy; Female; Genital Neoplasms, Female; Genitalia, Female; Humans; Neoplasms | 1963 |
[TREATMENT OF MALIGNANT TUMORS WITH TRIETHYLNETHIOPHOSPHAMIDE].
Topics: Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Humans; Laryngeal Neoplasms; Lung Neoplasms; Neop | 1963 |
[STATE OF HEMATOPOIESIS IN PATIENTS WITH CANCER OF THE OVARIES DURING THIO-TEPA THERAPY].
Topics: Bone Marrow Examination; Female; Geriatrics; Hematopoiesis; Humans; Leukocyte Count; Leukopenia; Neo | 1964 |
[ON THE EXPEDICIENCY OF PALLIATIVE STOMACH RESECTION COMBINED WITH CHEMOTHERAPY IN CANCER].
Topics: Digestive System Surgical Procedures; Gastrectomy; Humans; Lymphatic Metastasis; Neoplasms; Palliati | 1964 |
[PALLIATIVE TREATMENT OF CANCERS WITH THIO-TEPA. STUDY OF 115 CASES. VALUE IN BREAST CANCERS].
Topics: Biopsy; Breast Neoplasms; Female; Humans; Melanoma; Neoplasms; Ovarian Neoplasms; Palliative Care; R | 1964 |
EXPERIMENTAL CHEMOTHERAPY STUDIES. V. THE COLLATERAL SENSITIVITY TO ALKYLATING AGENTS OF SEVERAL ANTIMETABOLITE-RESISTANT ASCITES TUMORS IN MICE.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Ascites; Azaserine; Carcinoma, E | 1964 |
THE COMBINED THIOTEPA AND TESTOSTERONE TREATMENT OF CANCER OF THE BREAST.
Topics: Biomedical Research; Blood Platelets; Breast; Breast Neoplasms; Erythrocyte Count; Geriatrics; Hemat | 1964 |
A HISTOPATHOLOGIC STUDY ON THE EFFECT OF CHEMOTHERAPY IN MALIGNANT TUMOURS.
Topics: Cyclophosphamide; Humans; Mechlorethamine; Neoplasms; Thiotepa | 1964 |
TREATMENT OF NEOPLASTIC EFFUSIONS WITH CHLORAMBUCIL.
Topics: Ascites; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplasms; Pharmacology; Pleural Effusion; | 1964 |
[EXPERIENCE WITH ETHYLENEIMINES].
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Leukemi | 1964 |
[REGIONAL INTRA-ARTERIAL CHEMOTHERAPY OF MAXILLO-FACIAL CANCER].
Topics: Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Humans; Lip Neoplasms; | 1964 |
DISTRIBUTION OF C14-LABELED THIOTEPA (NSC-6396) AND ITS METABOLITES IN NORMAL AND TUMOR-BEARING RATS.
Topics: Animals; Autoradiography; Carcinoma; Carcinoma 256, Walker; Metabolism; Neoplasms; Rats; Research; T | 1964 |
OBSERVATIONS ON THE USE OF CANCER CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH MYCOSIS FUNGOIDES.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Carbamates; Chlorambucil; Dactinomy | 1964 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
REGRESSION OF METASTATIC HEPATOMEGALY FROM MAMMARY CARCINOMA. CYTOTOXIC COMBINATION CHEMOTHERAPY WITH 5-FU.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hepatomegaly; Humans; L | 1964 |
EFFECTS OF PERFUSION WITH THIOTEPA (NSC-6396) ON CARCINOMA VX2 IN HIND LEGS OF RABBITS.
Topics: Animals; Carcinoma; Leg; Neoplasms; Neoplasms, Experimental; Perfusion; Pharmacology; Rabbits; Resea | 1964 |
CYTOTOXIC DRUGS IN BRONCHIAL CARCINOMA.
Topics: Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Bronchogenic; Cyclophospha | 1964 |
NECROTIZING TOXOPLASMIC ENCEPHALITIS AND HERPETIC PNEUMONIA COMPLICATING TREATED HODGKIN'S DISEASE. REPORT OF A CASE.
Topics: Alkylating Agents; Antineoplastic Agents; Cyclophosphamide; Encephalitis; Herpesviridae Infections; | 1965 |
STUDIES WITH MUSTARDS. V. IN VIVO FIXATION OF C14 OF LABELED ALKYLATING AGENTS BY BILATERALLY GROWN SENSITIVE AND RESISTANT TUMORS.
Topics: Alkylating Agents; Animals; Carbon Isotopes; Cricetinae; Cyclophosphamide; DNA; DNA, Neoplasm; Mechl | 1964 |
CANCER CHEMOTHERAPY BY CONTINUOUS INTRA-ARTERIAL INFUSION. EXPERIENCE OF THE VETERANS ADMINISTRATION SURGICAL ADJUVANT CANCER CHEMOTHERAPY INFUSION STUDY GROUP.
Topics: Floxuridine; Geriatrics; Hemiplegia; Hemorrhage; Infusions, Intra-Arterial; Infusions, Parenteral; L | 1964 |
[ON THE ANTINEOPLASTIC ACTIVITY OF SOME FUROCOUMARINS].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Furans; Furocoumarins; Khellin; | 1964 |
IN VITRO CULTURE OF YOSHIDA SARCOMA CELLS: METHODS FOR DETERMINING ACQUIRED RESISTANCE TO DRUGS.
Topics: Animals; Antineoplastic Agents; Azaguanine; Culture Media; Cyclophosphamide; Dactinomycin; Drug Tole | 1964 |
[EXPERIMENTAL ANNOTATIONS ON THE INTRODUCTION OF DRUGS THROUGH THE LYMPHATIC SYSTEM].
Topics: Animals; Humans; Injections; Injections, Intralymphatic; Iodized Oil; Lymph Nodes; Lymphatic System; | 1964 |
CYCLOPHOSPHAMIDE IN TREATMENT OF LOCALLY RECURRENT BREAST CANCER.
Topics: Androgens; Breast; Breast Neoplasms; Cyclophosphamide; Drug Therapy; Estrogens; Humans; Hypophysecto | 1965 |
LOCAL ADJUVANT CHEMOTHERAPY IN THE SURGICAL MANAGEMENT OF CANCER.
Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; Intestin | 1964 |
[RESULTS OF THE TREATMENT OF RATS WITH TRANSPLANTED SARCOMA SSK WITH THIOTEPA ASSOCIATED WITH SOME PYRIMIDINE DERIVATIVES].
Topics: Antineoplastic Agents; Neoplasm Transplantation; Neoplasms; Pharmacology; Pyrimidines; Research; Sar | 1964 |
[EFFECTS OF COMBINED TREATMENT WITH AN ANTI-CANCER AGENT (THIO-TEPA) AND ADRENOCORTICAL STEROIDS FOR PROSTATIC CARCINOMA].
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Drug Therapy; Humans; Male; Neoplasms; Prostatic | 1964 |
[EVALUATION OF ADJUVANT POSTOPERATIVE CHEMOTHERAPY AND RADIATION THERAPY IN GASTRIC CANCER].
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Drug Therapy; Humans; Mitomycin; Mitomycins; Neoplasm | 1964 |
TREATMENT OF BLADDER TUMORS BY INSTILLATION OF THIO-TEPA, ACTINOMYCIN D, OR 5-FLUOROURACIL.
Topics: Carcinoma; Carcinoma, Papillary; Dactinomycin; Drug Therapy; Fluorouracil; Humans; Neoplasms; Thiote | 1965 |
THIOTEPA AND CYCLOPHOSPHAMIDE IN THE TREATMENT OF ADVANCED MAMMARY CANCER.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy; Geriatrics; Humans; Neoplasms; Thiotepa | 1965 |
[BONE MARROW TRANSPLANTATION IN RATS WITH M-1 SARCOMA AFTER ADMINISTRATION OF TOXIC DOSES OF THIO-TEPA].
Topics: Animals; Bone Marrow Transplantation; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Exp | 1965 |
USE OF THIO-TEPA AS AN ADJUVANT TO THE SURGICAL MANAGEMENT OF CARCINOMA OF THE STOMACH; V.A. COOPERATIVE SURGICAL ADJUVANT STUDY GROUP.
Topics: Carcinoma; Drug Therapy; Humans; Neoplasms; Stomach; Thiotepa | 1965 |
OUR EXPERIENCES WITH CYTOSTATIC PERFUSIONS OF THE EXTREMITIES IN THE TREATMENT OF MALIGNANT TUMORS.
Topics: Animals; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dogs; Drug Ther | 1964 |
[ANTI-CANCER CHEMOTHERAPY BY PROLONGED INTRA-ARTERIAL INFUSIONS].
Topics: Adrenal Cortex Hormones; Aminocaproates; Aminocaproic Acid; Anti-Bacterial Agents; Chemotherapy, Can | 1965 |
[EFFECT OF BONE MARROW TRANSPLANTATION IN THE TREATMENT OF SARCOMA-M-1 IN RATS WITH THIO-TEPA].
Topics: Animals; Bone Marrow Transplantation; Neoplasms; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1965 |
[TREATMENT OF CANCER OF THE THORACIC PORTION OF THE ESOPHAGUS].
Topics: Esophageal Neoplasms; Humans; Neoplasms; Surgical Procedures, Operative; Thiotepa | 1965 |
MALIGNANT PERICARDIAL EFFUSION. REVIEW OF HOSPITAL EXPERIENCE AND REPORT OF A CASE SUCCESSFULLY TREATED BY TALC POUDRAGE.
Topics: Breast Neoplasms; Cardiac Surgical Procedures; Cardiac Tamponade; Drug Therapy; Exudates and Transud | 1965 |
MULTIPLE TRACHEOBRONCHIAL MELANOMAS WITH TEN-YEAR SURVIVAL.
Topics: Bronchial Neoplasms; Cheek; Cobalt Isotopes; Drug Therapy; Head and Neck Neoplasms; Lymphedema; Lymp | 1965 |
OLFACTORY NEUROBLASTOMA.
Topics: Diagnosis, Differential; Drug Therapy; Esthesioneuroblastoma, Olfactory; Humans; Nasal Cavity; Neopl | 1965 |
DISSEMINATION OF CANCER WITH SPECIAL EMPHASIS ON VASCULAR SPREAD AND IMPLANTATION.
Topics: Geriatrics; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplasms; Ne | 1965 |
PREVENTION ON RECURRENCE OF PTERYGIUM.
Topics: Biomedical Research; Humans; Neoplasms; Preventive Medicine; Pterygium; Recurrence; Thiotepa | 1965 |
[CHANGES IN THE ANTITUMOR ACTIVITY OF THIOPHOSPHAMIDE WITH ADRENALIN UNDER EXPERIMENTAL CONDITIONS].
Topics: Animals; Epinephrine; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiot | 1964 |
CANCER CELLS IN BLOOD OF PATIENTS WITH MALIGNANT MELANOMA TREATED BY REGIONAL PERFUSION.
Topics: Blood; Cell Nucleus; Chemotherapy, Cancer, Regional Perfusion; Cytoplasm; Drug Therapy; Humans; Mela | 1965 |
[EFFECT OF THIO-TEPA ON THE BLOOD PROTEIN COMPOSITION IN SARCOMA M-1].
Topics: Blood Proteins; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1964 |
[EFFECT OF THIO-TEPA ON THE PHAGOCYTIC ACTIVITY OF LEUKOCYTES (EXPERIMENTAL STUDY)].
Topics: Animals; Leukocytes; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1964 |
THE TREATMENT OF ADVANCED CARCINOMA OF THE BLADDER.
Topics: Antimetabolites; Carcinoma; Cobalt Isotopes; Cyclophosphamide; Humans; Neoplasms; Palliative Care; P | 1965 |
[On the chemotherapy of malignant tumors with thioTEPA].
Topics: Antineoplastic Agents; Neoplasms; Thiotepa | 1959 |
[On the problem of the treatment of oncogynecological patients with N,N',N"-triethylenethio-phosphoramide (thio-tepa)].
Topics: Antineoplastic Agents; Genitalia; Genitalia, Female; Neoplasms; Phosphoramides; Thiotepa | 1960 |
Prolonged intravenous infusion chemotherapy of advanced cancer. I. Combined therapy with introgen mustard plus actinomycin D, thioTEPA plus actinomycin D, and thioTEPA plus actinomycin P2.
Topics: Antineoplastic Agents; Dactinomycin; Hydrocarbons; Infusions, Intravenous; Mechlorethamine; Mustard | 1961 |
[Use of thio TEPA in complex therapy of patients with malignant tumors of the ovary].
Topics: Antineoplastic Agents; Female; Humans; Neoplasms; Ovarian Neoplasms; Thiotepa | 1962 |
Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N"-triethylenethiophosphoramide (thiotepa) and N,N',N"-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ion
Topics: Antineoplastic Agents, Alkylating; Chromatography, High Pressure Liquid; Cyclophosphamide; Drug Moni | 2004 |
The treatment of neoplastic meningitis.
Topics: Antineoplastic Agents; Cytarabine; Humans; Injections, Intraventricular; Injections, Spinal; Meningi | 2004 |
Cutaneous effects of thiotepa in pediatric patients receiving high-dose chemotherapy with autologous stem cell transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclopho | 2008 |
[Endolymphatic use of solutions of alkylating substances in a mixture with iodolipol in malignant neoplasms].
Topics: Alkylating Agents; Cyclophosphamide; Drug Evaluation; Female; Humans; Injections, Intralymphatic; Io | 1981 |
The effect of thiophosphamide on the proliferative activity of human tumor cells cultured in vivo in diffusion chambers.
Topics: Animals; Breast Neoplasms; Cell Division; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Mice; M | 1984 |
Expression of adhesion molecules on CD34+ cells: CD34+ L-selectin+ cells predict a rapid platelet recovery after peripheral blood stem cell transplantation.
Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bon | 1995 |
Current position of vinorelbine in cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Ci | 1995 |
Effect of granulocyte-macrophage colony-stimulating factor on oral mucositis after hematopoietic stem-cell transplantation.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali | 1994 |
Pharmacokinetics and pharmacodynamics of carboplatin administered in a high-dose combination regimen with thiotepa, cyclophosphamide and peripheral stem cell support.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modalit | 1996 |
Mobilized peripheral blood progenitor cells (PBPC) in support of tandem cycles of high-dose chemotherapy (HDC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Trans | 1996 |
Pericardiocentesis and intrapericardial sclerosis: effective therapy for malignant pericardial effusions.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Drainage; | 1997 |
Double-conditioning regimens consisting of thiotepa, melphalan and busulfan with stem cell rescue for the treatment of pediatric solid tumors.
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; | 1998 |
Pilot trial of cytoprotection with amifostine given with high-dose chemotherapy and autologous peripheral blood stem cell transplantation.
Topics: Adult; Aged; Amifostine; Antiemetics; Antineoplastic Agents, Alkylating; Antineoplastic Combined Che | 2000 |
Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Cyclophosphamide; Drug Administra | 2000 |
Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy.
Topics: Adolescent; Adult; Algorithms; Analysis of Variance; Antineoplastic Agents, Alkylating; Area Under C | 2001 |
Glutamate antagonists limit tumor growth.
Topics: Anti-Anxiety Agents; Antineoplastic Agents; Benzodiazepines; Cell Division; Cell Movement; Cisplatin | 2001 |
Is pharmacokinetically guided chemotherapy dosage a better way forward?
Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Cyclophosphamide; Dis | 2002 |
Management of malignant pleural effusion.
Topics: Bleomycin; Fluorouracil; Gold Radioisotopes; Humans; Mechlorethamine; Methods; Neoplasms; Phosphorus | 1978 |
[Cytogenetic analysis of the damaging effect of thiophosphamide on the bone marrow of patients with malignant tumors].
Topics: Bone Marrow; Humans; Neoplasms; Thiotepa | 1979 |
Overview of early and investigational chemotherapeutic agents in solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aziridines; Azo Com | 1976 |
The effect of fractionated exposure to thio-TEPA upon Chinese hamster cells in vitro.
Topics: Animals; Cell Survival; Cricetinae; Drug Administration Schedule; In Vitro Techniques; Neoplasms; Th | 1976 |
Inhibition of collagen peptidase in HeLa cells and human tumours by compounds including drugs used in cancer therapy.
Topics: Antineoplastic Agents; Aprotinin; Collagen; Cyclophosphamide; Edetic Acid; Fluorouracil; HeLa Cells; | 1978 |
Fresh explant culture of human tumours in vitro and the assessment of sensitivity to cytotoxic chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Culture Techniques; Drug Evaluation, Preclini | 1975 |
Immunological overshoot phenomenon following cancer chemotherapy: significance in prognosis evaluation of solid tumors.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immune | 1975 |
Toxicity, antitumor activity, and pharmacokinetics of spin-labeled thioTEPA analogs.
Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinic | 1976 |
Pharmacokinetics of high dose thiotepa in children undergoing autologous bone marrow transplantation.
Topics: Bone Marrow Transplantation; Child; Child, Preschool; Female; Humans; Infusions, Intravenous; Male; | 1992 |
[Use of mathematical modelling for calculating the optimal plan for administration of the antineoplastic agent thiophosphamide].
Topics: Antineoplastic Agents; Drug Administration Schedule; Models, Theoretical; Neoplasms; Thiotepa | 1992 |
High-dose thiotepa with autologous bone marrow rescue in pediatric solid tumors.
Topics: Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Evaluat | 1991 |
Thiotepa.
Topics: Humans; Neoplasms; Thiotepa | 1991 |
High-dose tri-alkylator chemotherapy with autologous stem cell rescue in patients with refractory malignancies.
Topics: Adult; Alkylating Agents; Carmustine; Combined Modality Therapy; Cyclophosphamide; Female; Hematopoi | 1990 |
Symposium on bone marrow transplantation. September 9, 1989, Dallas, TX. Proceedings.
Topics: Animals; Bone Marrow Transplantation; Combined Modality Therapy; Humans; Neoplasms; Thiotepa | 1990 |
Phase I trial of escalating pentoxifylline dose with constant dose thiotepa.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug | 1990 |
A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1990 |
[A study to overcome drug resistance using high-dose chemotherapy with autologous bone marrow transplantation].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Colony-Stimulati | 1989 |
A phase I study of thiotepa administered by short-term and protracted continuous intravenous infusion.
Topics: Adult; Aged; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukocyte Count; | 1989 |
Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa.
Topics: Adolescent; Adult; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation; Femal | 1989 |
Lucy Wortham James lecture. Regional perfusion. Current sophistication, what next?
Topics: Animals; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Costs and Cost Analysis; E | 1986 |
Pharmacokinetics of continuous-infusion high-dose thiotepa.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Evaluation; Female; Hu | 1987 |
Human plasma pharmacokinetics of thiotepa following administration of high-dose thiotepa and cyclophosphamide.
Topics: Chromatography, Gas; Cyclophosphamide; Drug Evaluation; Female; Half-Life; Humans; Infusions, Intrav | 1988 |
Cyclophosphamide and thiotepa with autologous bone marrow transplantation in patients with solid tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide | 1988 |
A predictive approach to selecting the size of a clinical trial, based on subjective clinical opinion.
Topics: Administration, Intravesical; Clinical Trials as Topic; Combined Modality Therapy; Drug Administrati | 1988 |
[Chemotherapy of so-called solid tumors].
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Synergism; Fluorouracil; Humans; Immunos | 1971 |
[Mitomycin alone and in therapeutic association in the palliative treatment of solid tumors].
Topics: Antineoplastic Agents; Breast Neoplasms; Cobalt Isotopes; Cyclophosphamide; Drug Combinations; Femal | 1971 |
Place of chemotherapy in the management of malignant diseases. A retrospective study of 86 cases.
Topics: Alkylating Agents; Cyclophosphamide; Humans; Mechlorethamine; Mitomycins; Neoplasms; Palliative Care | 1974 |
Effects of antitumor agents and hyperbaric oxygen in normal and tumor-bearing rodents.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Hyperbaric Oxygenation; Mechloretham | 1966 |
[Combination of chemotherapy and surgical treatment of malignant tumors].
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Female; Hodgkin Disease | 1967 |
[Use of thermal effects in the compound treatment of malignant tumors].
Topics: Adolescent; Adult; Chemotherapy, Cancer, Regional Perfusion; Diathermy; Electric Stimulation Therapy | 1973 |
[Chemoradiation treatment of neglected forms of malignant neoplasms].
Topics: Antineoplastic Agents; Cyclophosphamide; Female; Humans; Male; Melphalan; Neoplasms; Radiotherapy Do | 1973 |
[Chromosomal studies in correlation with other biologic constants in neoplasms treated by chemotherapy].
Topics: Adult; Antibody Formation; Bone Marrow; Cell Division; Chromosome Aberrations; Female; Fluorouracil; | 1974 |
[Blood changes in hyperthermic perfusion with chemotherapeutic preparations].
Topics: Blood; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Hyperthermia, Induced; Melphal | 1974 |
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamid | 1968 |
In vitro test for sensitivity of tumor to carcinostatic agents.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carcinoma, He | 1966 |
[On a test for the choice of antitumoral drugs].
Topics: Antineoplastic Agents; Cyclophosphamide; Diethylstilbestrol; Estrogens, Conjugated (USP); Humans; Ne | 1968 |
Kinetics and the free-radical mechanisms of tumor growth.
Topics: Animals; Benzyl Compounds; Brain; DDT; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; | 1973 |
Treatment of head and neck cancer with intra-arterial cytotoxic drugs and radiotherapy.
Topics: Antineoplastic Agents; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexa | 1972 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; | 1972 |
[New possibilities in testing resistance of human carcinoma tissue to cytostatic agents in vivo].
Topics: Animals; Cyclophosphamide; Humans; Methotrexate; Neoplasm Transplantation; Neoplasms; Phytotherapy; | 1967 |
The study by graphical analysis of the growth of human tumours and metastases of the lung.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Kidney Neoplasms; Lung Neoplasms; Mathemati | 1967 |
[Regional chemotherapy of malignant tumors by the method of intraarterial infusion (experimental study)].
Topics: Animals; Carbon Isotopes; Chemotherapy, Cancer, Regional Perfusion; Dogs; Female; Injections, Intra- | 1966 |
[The state of hemopoiesis in the regional perfusion of malignant tumors of the extremities with sarcolysin, thio-TEPA and cyclophosphane].
Topics: Adolescent; Adult; Aged; Bone Marrow; Child; Cyclophosphamide; Extremities; Female; Hematopoiesis; H | 1967 |
[The chemotherapy of cancer].
Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil | 1967 |
[Effect of zymosan on the peripheral blood picture (clinical cases)].
Topics: Cyclophosphamide; Hematopoiesis; Humans; Leukocytes; Neoplasms; Thiotepa; Zymosan | 1968 |
[Changes in hemopoiesis of patients with cancer during chemotherapy in relation to the nutritional factor (proteins and vitamins--C and B complex].
Topics: Aged; Ascorbic Acid; Dietary Proteins; Female; Hematopoiesis; Humans; Leukopenia; Male; Middle Aged; | 1968 |
[Status of the blood after perfusion with various doses of chemopreparations and the efficiency of an artificial ciruclation device in malignant tumors of the extremities].
Topics: Extracorporeal Circulation; Extremities; Hematologic Diseases; Humans; Melphalan; Neoplasms; Perfusi | 1968 |
Combined chemotherapy in the treatment of malignant effusions.
Topics: Alkylating Agents; Antineoplastic Agents; Ascites; Ascitic Fluid; Blood Cell Count; Blood Platelets; | 1969 |
Intracavitary thiotepa in malignant pleural and peritoneal effusions.
Topics: Adult; Aged; Breast Neoplasms; Child; Exudates and Transudates; Female; Follow-Up Studies; Gastroint | 1968 |
[The hypoplastic state of hematopoiesis following chemotherapy with alkylating compounds].
Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Female; Hematologic Disease | 1969 |
Management of effusions.
Topics: Alkylating Agents; Ascites; Diuretics; Drainage; Fluorine; Gold Isotopes; Humans; Irritants; Neoplas | 1970 |
Chemotherapy and radiation therapy together to treat cancer.
Topics: Antineoplastic Agents; Cell Division; Cyclophosphamide; DNA, Neoplasm; Female; Fluorouracil; Heparin | 1970 |
Comparison of a combination of 5-fluorouracil (NSC-19893), mitomycin C (NSC-26980), triethylenethiophosphoramide (NSC-6396), and fluoxymesterone (NSC-12165) with 5-fluorouracil alone in patients with advanced cancer.
Topics: Antineoplastic Agents; Fluorouracil; Fluoxymesterone; Humans; Mitomycins; Neoplasms; Thiotepa | 1968 |
[Combined treatment of malignant tumors of the extremities. Regional perfusion chemotherapy].
Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Extremities; Humans; Melanoma; Melphalan; Neopl | 1970 |
[Clinico-electrocardiographic changes during perfusion chemotherapy of malignant tumors of the extremities].
Topics: Adolescent; Adult; Aged; Anemia; Cardiomyopathies; Chemotherapy, Cancer, Regional Perfusion; Child; | 1970 |
[Chemotherapy of solid tumors].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Fluorour | 1970 |
Cytological studies on exfoliated cells in serous effusions.
Topics: Ascitic Fluid; Blood Cells; Histiocytes; Humans; Mannomustine; Neoplasm Metastasis; Neoplasms; Pleur | 1970 |
[The clinical evaluation of cytotoxic agents based on their inhibition of tumor growth in vitro].
Topics: Cyclophosphamide; Dactinomycin; Evaluation Studies as Topic; Female; Fluorouracil; Humans; In Vitro | 1971 |
[The efficacy of intralymphatic use of antiblastic drugs].
Topics: Animals; Antineoplastic Agents; Cats; Cyclophosphamide; Dogs; Female; Gold Colloid, Radioactive; Hod | 1969 |