Page last updated: 2024-11-05

thiotepa and Benign Infratentorial Neoplasms

thiotepa has been researched along with Benign Infratentorial Neoplasms in 3 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"The aim of the study is to evaluate the outcome of young children with high risk localized medulloblastomas (newly diagnosed classical or incompletely resected) treated by high-dose busulfan-thiotepa with autologous stem cell rescue (ASCT) followed by focal radiation therapy (RT)."7.80High-dose busulfan-thiotepa with autologous stem cell transplantation followed by posterior fossa irradiation in young children with classical or incompletely resected medulloblastoma. ( Bergthold, G; Dhermain, F; Dufour, C; El Kababri, M; Goma, G; Grill, J; Kieffer, V; Raquin, MA; Sainte-Rose, C; Valteau-Couanet, D; Varlet, P, 2014)
"The aim of the study is to evaluate the outcome of young children with high risk localized medulloblastomas (newly diagnosed classical or incompletely resected) treated by high-dose busulfan-thiotepa with autologous stem cell rescue (ASCT) followed by focal radiation therapy (RT)."3.80High-dose busulfan-thiotepa with autologous stem cell transplantation followed by posterior fossa irradiation in young children with classical or incompletely resected medulloblastoma. ( Bergthold, G; Dhermain, F; Dufour, C; El Kababri, M; Goma, G; Grill, J; Kieffer, V; Raquin, MA; Sainte-Rose, C; Valteau-Couanet, D; Varlet, P, 2014)
"Patients with infratentorial brain metastases of highly malignant pediatric non-epithelial tumors are in a severe clinical state, but still can have longer and useful lives with aggressive multimodal treatments combined with radical surgical resection."1.37Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports. ( Kumabe, T; Niizuma, H; Osawa, S; Saito, R; Sonoda, Y; Tominaga, T; Watanabe, M, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergthold, G1
El Kababri, M1
Varlet, P1
Dhermain, F1
Sainte-Rose, C1
Raquin, MA1
Kieffer, V1
Goma, G1
Grill, J1
Valteau-Couanet, D1
Dufour, C1
Osawa, S1
Kumabe, T1
Saito, R1
Sonoda, Y1
Niizuma, H1
Watanabe, M1
Tominaga, T1
Fangusaro, JR1
Jubran, RF1
Allen, J1
Gardner, S1
Dunkel, IJ1
Rosenblum, M1
Atlas, MP1
Gonzalez-Gomez, I1
Miller, D1
Finlay, JL1

Trials

1 trial available for thiotepa and Benign Infratentorial Neoplasms

ArticleYear
Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Damage, Chronic;

2008

Other Studies

2 other studies available for thiotepa and Benign Infratentorial Neoplasms

ArticleYear
High-dose busulfan-thiotepa with autologous stem cell transplantation followed by posterior fossa irradiation in young children with classical or incompletely resected medulloblastoma.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cerebellar Neoplasms; Child, Preschool; Co

2014
Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports.
    Brain tumor pathology, 2011, Volume: 28, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin

2011