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thiotepa and Atrophy

thiotepa has been researched along with Atrophy in 1 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"To clarify the relationship of microvascular events in the bone marrow to the development of and the recovery from bone atrophy, we examined quantitatively and qualitatively trabecular bone, sinusoids and haematopoietic tissue in the metaphysis of the tibia of rats given thiotepa, an antitumour drug derived from nitrogen mustards."7.68Microvascular events in bone marrow related to development of and recovery from bone atrophy in thiotepa-treated rats. ( Nakata, K; Nishimoto, M; Shibayama, Y, 1993)
"To clarify the relationship of microvascular events in the bone marrow to the development of and the recovery from bone atrophy, we examined quantitatively and qualitatively trabecular bone, sinusoids and haematopoietic tissue in the metaphysis of the tibia of rats given thiotepa, an antitumour drug derived from nitrogen mustards."3.68Microvascular events in bone marrow related to development of and recovery from bone atrophy in thiotepa-treated rats. ( Nakata, K; Nishimoto, M; Shibayama, Y, 1993)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shibayama, Y1
Nishimoto, M1
Nakata, K1

Other Studies

1 other study available for thiotepa and Atrophy

ArticleYear
Microvascular events in bone marrow related to development of and recovery from bone atrophy in thiotepa-treated rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1993, Volume: 45, Issue:2-3

    Topics: Animals; Atrophy; Body Weight; Bone and Bones; Bone Marrow; Female; Rats; Rats, Wistar; Thiotepa; Ti

1993