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thiotepa and Anaplastic Oligodendroglioma

thiotepa has been researched along with Anaplastic Oligodendroglioma in 7 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Research Excerpts

ExcerptRelevanceReference
"We previously reported a phase 2 trial of 69 patients with newly diagnosed anaplastic or aggressive oligodendroglioma who were treated with intensive procarbazine, CCNU (lomustine), and vincristine (PCV) followed by high-dose thiotepa with autologous stem cell rescue."5.12High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up. ( Abrey, LE; Bayer, R; Cairncross, JG; Childs, BH; DeAngelis, LM; Finlay, JL; Forsyth, P; Gardner, S; Hu, W; Kaminer, L; Macdonald, DR; Nimer, SD; Paleologos, N; Peterson, K; Ramsay, DA; Rosenfeld, S; Salzman, D; Smith, AM; Stewart, D; Swinnen, L; Weaver, S, 2006)
"Anaplastic oligodendroglioma is a chemosensitive glial neoplasm."2.71High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma. ( Abrey, LE; Bayer, R; Cairncross, JG; Childs, BH; DeAngelis, LM; Finlay, JL; Forsyth, P; Gardner, S; Hu, W; Kaminer, L; Macdonald, DR; Nimer, SD; Paleologos, N; Peterson, K; Ramsey, DA; Rosenfeld, S; Salzman, D; Smith, AM; Stewart, D; Swinnen, L; Weaver, S, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abrey, LE3
Childs, BH2
Paleologos, N4
Kaminer, L3
Rosenfeld, S3
Salzman, D3
Finlay, JL2
Gardner, S2
Peterson, K3
Hu, W3
Swinnen, L3
Bayer, R3
Forsyth, P4
Stewart, D4
Smith, AM2
Macdonald, DR2
Weaver, S2
Ramsey, DA1
Nimer, SD2
DeAngelis, LM2
Cairncross, JG3
Thorarinsdottir, HK1
Rood, B2
Kamani, N2
Lafond, D1
Perez-Albuerne, E1
Loechelt, B1
Packer, RJ2
MacDonald, TJ2
Ramsay, DA1
Choi, LM1
La Fond, D1
Santi, MR1
Mohile, NA1
Raizer, JJ1
Kewalramani, T1
Louis, DN1
Cairncross, G1
Macdonald, D1
Ramsay, D1
Smith, A1
Saarinen, UM1
Pihko, H1
Mäkipernaa, A1

Trials

3 trials available for thiotepa and Anaplastic Oligodendroglioma

ArticleYear
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2003, Volume: 65, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2003
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up.
    Neuro-oncology, 2006, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Busulfan; Combi

2008

Other Studies

4 other studies available for thiotepa and Anaplastic Oligodendroglioma

ArticleYear
Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child, Preschool; Cisp

2007
Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant

2008
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
    Neuro-oncology, 2000, Volume: 2, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta

2000
High-dose thiotepa with autologous bone marrow rescue in recurrent malignant oligodendroglioma: a case report.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:1

    Topics: Bone Marrow Transplantation; Brain Neoplasms; Child; Combined Modality Therapy; Dose-Response Relati

1990