thiotepa has been researched along with Anaplastic Oligodendroglioma in 7 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously reported a phase 2 trial of 69 patients with newly diagnosed anaplastic or aggressive oligodendroglioma who were treated with intensive procarbazine, CCNU (lomustine), and vincristine (PCV) followed by high-dose thiotepa with autologous stem cell rescue." | 5.12 | High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up. ( Abrey, LE; Bayer, R; Cairncross, JG; Childs, BH; DeAngelis, LM; Finlay, JL; Forsyth, P; Gardner, S; Hu, W; Kaminer, L; Macdonald, DR; Nimer, SD; Paleologos, N; Peterson, K; Ramsay, DA; Rosenfeld, S; Salzman, D; Smith, AM; Stewart, D; Swinnen, L; Weaver, S, 2006) |
| "Anaplastic oligodendroglioma is a chemosensitive glial neoplasm." | 2.71 | High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma. ( Abrey, LE; Bayer, R; Cairncross, JG; Childs, BH; DeAngelis, LM; Finlay, JL; Forsyth, P; Gardner, S; Hu, W; Kaminer, L; Macdonald, DR; Nimer, SD; Paleologos, N; Peterson, K; Ramsey, DA; Rosenfeld, S; Salzman, D; Smith, AM; Stewart, D; Swinnen, L; Weaver, S, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrey, LE | 3 |
| Childs, BH | 2 |
| Paleologos, N | 4 |
| Kaminer, L | 3 |
| Rosenfeld, S | 3 |
| Salzman, D | 3 |
| Finlay, JL | 2 |
| Gardner, S | 2 |
| Peterson, K | 3 |
| Hu, W | 3 |
| Swinnen, L | 3 |
| Bayer, R | 3 |
| Forsyth, P | 4 |
| Stewart, D | 4 |
| Smith, AM | 2 |
| Macdonald, DR | 2 |
| Weaver, S | 2 |
| Ramsey, DA | 1 |
| Nimer, SD | 2 |
| DeAngelis, LM | 2 |
| Cairncross, JG | 3 |
| Thorarinsdottir, HK | 1 |
| Rood, B | 2 |
| Kamani, N | 2 |
| Lafond, D | 1 |
| Perez-Albuerne, E | 1 |
| Loechelt, B | 1 |
| Packer, RJ | 2 |
| MacDonald, TJ | 2 |
| Ramsay, DA | 1 |
| Choi, LM | 1 |
| La Fond, D | 1 |
| Santi, MR | 1 |
| Mohile, NA | 1 |
| Raizer, JJ | 1 |
| Kewalramani, T | 1 |
| Louis, DN | 1 |
| Cairncross, G | 1 |
| Macdonald, D | 1 |
| Ramsay, D | 1 |
| Smith, A | 1 |
| Saarinen, UM | 1 |
| Pihko, H | 1 |
| Mäkipernaa, A | 1 |
3 trials available for thiotepa and Anaplastic Oligodendroglioma
| Article | Year |
|---|---|
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin | 2003 |
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brai | 2006 |
A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Busulfan; Combi | 2008 |
4 other studies available for thiotepa and Anaplastic Oligodendroglioma
| Article | Year |
|---|---|
Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child, Preschool; Cisp | 2007 |
Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant | 2008 |
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta | 2000 |
High-dose thiotepa with autologous bone marrow rescue in recurrent malignant oligodendroglioma: a case report.
Topics: Bone Marrow Transplantation; Brain Neoplasms; Child; Combined Modality Therapy; Dose-Response Relati | 1990 |