thiotepa has been researched along with Anaplastic Oligodendroglioma in 7 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Excerpt | Relevance | Reference |
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"We previously reported a phase 2 trial of 69 patients with newly diagnosed anaplastic or aggressive oligodendroglioma who were treated with intensive procarbazine, CCNU (lomustine), and vincristine (PCV) followed by high-dose thiotepa with autologous stem cell rescue." | 5.12 | High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up. ( Abrey, LE; Bayer, R; Cairncross, JG; Childs, BH; DeAngelis, LM; Finlay, JL; Forsyth, P; Gardner, S; Hu, W; Kaminer, L; Macdonald, DR; Nimer, SD; Paleologos, N; Peterson, K; Ramsay, DA; Rosenfeld, S; Salzman, D; Smith, AM; Stewart, D; Swinnen, L; Weaver, S, 2006) |
"Anaplastic oligodendroglioma is a chemosensitive glial neoplasm." | 2.71 | High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma. ( Abrey, LE; Bayer, R; Cairncross, JG; Childs, BH; DeAngelis, LM; Finlay, JL; Forsyth, P; Gardner, S; Hu, W; Kaminer, L; Macdonald, DR; Nimer, SD; Paleologos, N; Peterson, K; Ramsey, DA; Rosenfeld, S; Salzman, D; Smith, AM; Stewart, D; Swinnen, L; Weaver, S, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 6 (85.71) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abrey, LE | 3 |
Childs, BH | 2 |
Paleologos, N | 4 |
Kaminer, L | 3 |
Rosenfeld, S | 3 |
Salzman, D | 3 |
Finlay, JL | 2 |
Gardner, S | 2 |
Peterson, K | 3 |
Hu, W | 3 |
Swinnen, L | 3 |
Bayer, R | 3 |
Forsyth, P | 4 |
Stewart, D | 4 |
Smith, AM | 2 |
Macdonald, DR | 2 |
Weaver, S | 2 |
Ramsey, DA | 1 |
Nimer, SD | 2 |
DeAngelis, LM | 2 |
Cairncross, JG | 3 |
Thorarinsdottir, HK | 1 |
Rood, B | 2 |
Kamani, N | 2 |
Lafond, D | 1 |
Perez-Albuerne, E | 1 |
Loechelt, B | 1 |
Packer, RJ | 2 |
MacDonald, TJ | 2 |
Ramsay, DA | 1 |
Choi, LM | 1 |
La Fond, D | 1 |
Santi, MR | 1 |
Mohile, NA | 1 |
Raizer, JJ | 1 |
Kewalramani, T | 1 |
Louis, DN | 1 |
Cairncross, G | 1 |
Macdonald, D | 1 |
Ramsay, D | 1 |
Smith, A | 1 |
Saarinen, UM | 1 |
Pihko, H | 1 |
Mäkipernaa, A | 1 |
3 trials available for thiotepa and Anaplastic Oligodendroglioma
Article | Year |
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High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin | 2003 |
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brai | 2006 |
A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Busulfan; Combi | 2008 |
4 other studies available for thiotepa and Anaplastic Oligodendroglioma
Article | Year |
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Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child, Preschool; Cisp | 2007 |
Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant | 2008 |
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta | 2000 |
High-dose thiotepa with autologous bone marrow rescue in recurrent malignant oligodendroglioma: a case report.
Topics: Bone Marrow Transplantation; Brain Neoplasms; Child; Combined Modality Therapy; Dose-Response Relati | 1990 |