thiotepa has been researched along with Anaplastic Ependymoma in 6 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "By conventional Phase II criteria, thiotepa appears to have activity in medulloblastoma." | 5.07 | A phase II evaluation of thiotepa in pediatric central nervous system malignancies. ( Allen, JC; Balis, FM; Gillespie, A; Heideman, RL; Horowitz, ME; Kovnar, EH; Lange, B; Packer, RJ; Reaman, GH; Steinberg, SM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thorarinsdottir, HK | 1 |
| Rood, B | 1 |
| Kamani, N | 1 |
| Lafond, D | 1 |
| Perez-Albuerne, E | 1 |
| Loechelt, B | 1 |
| Packer, RJ | 2 |
| MacDonald, TJ | 1 |
| Zacharoulis, S | 1 |
| Levy, A | 1 |
| Chi, SN | 1 |
| Gardner, S | 1 |
| Rosenblum, M | 1 |
| Miller, DC | 1 |
| Dunkel, I | 1 |
| Diez, B | 1 |
| Sposto, R | 1 |
| Ji, L | 1 |
| Asgharzadeh, S | 1 |
| Hukin, J | 1 |
| Belasco, J | 1 |
| Dubowy, R | 1 |
| Kellie, S | 1 |
| Termuhlen, A | 1 |
| Finlay, J | 1 |
| Heideman, RL | 1 |
| Reaman, GH | 1 |
| Allen, JC | 1 |
| Lange, B | 1 |
| Horowitz, ME | 1 |
| Steinberg, SM | 1 |
| Gillespie, A | 1 |
| Kovnar, EH | 1 |
| Balis, FM | 1 |
| Grill, J | 2 |
| Kalifa, C | 2 |
| Doz, F | 1 |
| Schoepfer, C | 1 |
| Sainte-Rose, C | 1 |
| Couanet, D | 1 |
| Terrier-Lacombe, MJ | 1 |
| Valteau-Couanet, D | 1 |
| Hartmann, O | 1 |
| Wilkinson, HA | 1 |
| Kornblith, P | 1 |
| Weems, S | 1 |
2 trials available for thiotepa and Anaplastic Ependymoma
| Article | Year |
|---|---|
A phase II evaluation of thiotepa in pediatric central nervous system malignancies.
Topics: Adolescent; Adult; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Drug Administrati | 1993 |
A high-dose busulfan-thiotepa combination followed by autologous bone marrow transplantation in childhood recurrent ependymoma. A phase-II study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neopl | 1996 |
4 other studies available for thiotepa and Anaplastic Ependymoma
| Article | Year |
|---|---|
Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child, Preschool; Cisp | 2007 |
Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschoo | 2007 |
High dose chemotherapy for childhood ependymona.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; | 1998 |
Focal chemotherapy of brain tumours using semipermeable membranes.
Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Dactinomycin; Ependymoma; Fluorouracil; | 1977 |