thiotepa and Aging
thiotepa has been researched along with Aging in 4 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "In C57BL/6 mice the level of induced chromosome aberrations was found to be age-independent." | 1.26 | [Spontaneous and induced chromosome aberrations in the bone marrow cells of different strains of mice during aging]. ( Korogodina, IuV; Lil'p, IG, 1981) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| NANJO, H | 1 |
| Lil'p, IG | 1 |
| Korogodina, IuV | 1 |
| Leonard, A | 1 |
| Jacquet, P | 1 |
| Subrahmanyan, TP | 1 |
Other Studies
4 other studies available for thiotepa and Aging
| Article | Year |
|---|---|
[MATERNAL AGE OF MICE AND THE ADMINISTRATION OF THIO-TEPA DURING PREGNANCY AS RELATED TO THE MALFORMATION OF THE FETUS].
Topics: Abnormalities, Drug-Induced; Aging; Animals; Female; Fetus; Humans; Maternal Age; Mice; Pharmacology | 1964 |
[Spontaneous and induced chromosome aberrations in the bone marrow cells of different strains of mice during aging].
Topics: Aging; Animals; Bone Marrow; Chromosome Aberrations; Gamma Rays; Genotype; Male; Mice; Mice, Inbred | 1981 |
[Effect of age on the sensitivity of mouse spermatogonia to mutagenic action].
Topics: Aging; Animals; Dose-Response Relationship, Radiation; Male; Mice; Mutation; Spermatogonia; Spermato | 1978 |
Effect of neonatal thymectomy and thiotepa on the susceptibility of mice to the lethal effects of poxviruses.
Topics: Aging; Animals; Antibody Formation; Antigen-Antibody Reactions; Chloramphenicol; Ectromelia virus; G | 1968 |