Page last updated: 2024-11-05

thiotepa and Aging

thiotepa has been researched along with Aging in 4 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"In C57BL/6 mice the level of induced chromosome aberrations was found to be age-independent."1.26[Spontaneous and induced chromosome aberrations in the bone marrow cells of different strains of mice during aging]. ( Korogodina, IuV; Lil'p, IG, 1981)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
NANJO, H1
Lil'p, IG1
Korogodina, IuV1
Leonard, A1
Jacquet, P1
Subrahmanyan, TP1

Other Studies

4 other studies available for thiotepa and Aging

ArticleYear
[MATERNAL AGE OF MICE AND THE ADMINISTRATION OF THIO-TEPA DURING PREGNANCY AS RELATED TO THE MALFORMATION OF THE FETUS].
    Kaibogaku zasshi. Journal of anatomy, 1964, Dec-01, Volume: 39

    Topics: Abnormalities, Drug-Induced; Aging; Animals; Female; Fetus; Humans; Maternal Age; Mice; Pharmacology

1964
[Spontaneous and induced chromosome aberrations in the bone marrow cells of different strains of mice during aging].
    Tsitologiia, 1981, Volume: 23, Issue:10

    Topics: Aging; Animals; Bone Marrow; Chromosome Aberrations; Gamma Rays; Genotype; Male; Mice; Mice, Inbred

1981
[Effect of age on the sensitivity of mouse spermatogonia to mutagenic action].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1978, Volume: 172, Issue:5

    Topics: Aging; Animals; Dose-Response Relationship, Radiation; Male; Mice; Mutation; Spermatogonia; Spermato

1978
Effect of neonatal thymectomy and thiotepa on the susceptibility of mice to the lethal effects of poxviruses.
    The Australian journal of experimental biology and medical science, 1968, Volume: 46, Issue:3

    Topics: Aging; Animals; Antibody Formation; Antigen-Antibody Reactions; Chloramphenicol; Ectromelia virus; G

1968