thiotepa has been researched along with Abnormalities, Drug-Induced in 13 studies
Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| NISHIKAWA, M | 1 |
| NANJO, H | 1 |
| Fujii, T | 1 |
| Nakatsuka, T | 1 |
| Korogodina, IuV | 1 |
| Kaurov, BA | 1 |
| Kurilo, LF | 1 |
| Pannuti, F | 1 |
| Barboni, F | 1 |
| Nishimura, H | 4 |
| Terada, M | 1 |
| Yasuda, M | 1 |
| Takano, K | 1 |
| Tanimura, T | 4 |
| Takino, T | 1 |
| Yamamura, H | 1 |
| Okada, T | 1 |
| Tanaka, T | 1 |
1 review available for thiotepa and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Cytogenetic and cytological approaches to detection of gamete abnormalities (review of the literature)].
Topics: Abnormalities, Drug-Induced; Animals; Female; In Vitro Techniques; Male; Mice; Mutagenicity Tests; M | 1989 |
12 other studies available for thiotepa and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[TERATOGENIC EFFECT OF A COMBINATION OF FASTING AND THIO-TEPA ADMINISTRATION IN PREGNANT MICE].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Fasting; Female; Humans; Mice; Pharm | 1964 |
[MATERNAL AGE OF MICE AND THE ADMINISTRATION OF THIO-TEPA DURING PREGNANCY AS RELATED TO THE MALFORMATION OF THE FETUS].
Topics: Abnormalities, Drug-Induced; Aging; Animals; Female; Fetus; Humans; Maternal Age; Mice; Pharmacology | 1964 |
Potentiating effects of caffeine on teratogenicity of alkylating agents in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Alkylating Agents; Animals; Antibioti | 1983 |
[Teratogenic effect of thiophosphamide on mice of different genotypes].
Topics: Abnormalities, Drug-Induced; Animals; Female; Genotype; Mice; Mice, Inbred Strains; Pregnancy; Terat | 1984 |
[Histopathological study of the heart-damaging effects of thio-tepa in the chick embryo "in situ". 3].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Fetus; Heart; Heart Defects, Congenital; Thiotep | 1972 |
Mitigated teratogenicity of thio-TEPA in goldthioglucose obese mice.
Topics: Abnormalities, Drug-Induced; Animals; Clubfoot; Female; Fingers; Glucose; Gold; Mice; Obesity; Pregn | 1967 |
The susceptibility of the offspring of alloxandiabetic mice to a teratogen.
Topics: Abnormalities, Drug-Induced; Animals; Diabetes Mellitus, Experimental; Female; Fetus; Maternal-Fetal | 1965 |
Modification of the teratogenic effect of thio-TEPA on the mouse offspring by successive maternal treatment with tolbutamide.
Topics: Abnormalities, Drug-Induced; Animals; Female; Mice; Pregnancy; Thiotepa; Tolbutamide | 1966 |
[Effect of thio-TEPA on the forelimb buds of the mouse embryo in vitro].
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Extremities; Female; In Vitro Techniques; Male; Mes | 1966 |
[Postnatal fate of mice subjected to thio-TEPA during the embryonic stage].
Topics: Abnormalities, Drug-Induced; Animals; Female; Male; Mice; Pregnancy; Thiotepa | 1967 |
Relationship of dosage and time of administration to the teratogenic effects of thio-TEPA in mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Maternal-Fetal Exchange; Mice; Placenta; Pregnancy; Pr | 1968 |
Modification of the teratogenic effects of certain antineoplastic agents by combined treatment with vitamins.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Drug Antagonism; Drug Synergism; Female; Fetal De | 1968 |