thiosulfates has been researched along with Methemoglobinemia in 11 studies
Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether sodium thiosulfate (STS) produces a clinically significant decline in sodium nitrite-induced methemoglobinemia in an in-vitro model." | 9.10 | Sodium thiosulfate fails to reduce nitrite-induced methemoglobinemia in vitro. ( Matteucci, MJ; Reed, WJ; Tanen, DA, 2003) |
| "To determine whether sodium thiosulfate (STS) produces a clinically significant decline in sodium nitrite-induced methemoglobinemia in an in-vitro model." | 5.10 | Sodium thiosulfate fails to reduce nitrite-induced methemoglobinemia in vitro. ( Matteucci, MJ; Reed, WJ; Tanen, DA, 2003) |
| "The administration of sodium nitrite to smoke inhalation patients in the presence of concomitant carbon monoxide poisoning may be relatively safe." | 3.68 | Cyanide and methemoglobin kinetics in smoke inhalation victims treated with the cyanide antidote kit. ( Gerace, R; Kirk, MA; Kulig, KW, 1993) |
| " A patient with severe hydrogen sulfide poisoning and consequent profound metabolic acidosis was treated successfully with nitrites and oxygen." | 3.65 | Hydrogen sulfide intoxication. A case report and discussion of treatment. ( Beacham, BE; Slosberg, B; Stine, RJ, 1976) |
| " Nitrite should not be given if the poisoning is mild or diagnosis is uncertain, to avoid excessive methemoglobin, dosage of sodium nitrite must be adjusted according to hemoglobin level (Table 1)." | 1.28 | Acute cyanide poisoning: a case report with toxicokinetic study. ( Kaojarern, S; Wananukul, W, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mintegi, S | 1 |
| Clerigue, N | 1 |
| Tipo, V | 1 |
| Ponticiello, E | 1 |
| Lonati, D | 1 |
| Burillo-Putze, G | 1 |
| Delvau, N | 1 |
| Anseeuw, K | 1 |
| Matteucci, MJ | 1 |
| Reed, WJ | 1 |
| Tanen, DA | 1 |
| Willhite, CC | 1 |
| Smith, RP | 2 |
| Kong, A | 1 |
| Shen, A | 1 |
| Burrows, G | 1 |
| Sylvester, D | 1 |
| Isom, GE | 1 |
| Way, JL | 1 |
| Nomura, A | 1 |
| Kirk, MA | 1 |
| Gerace, R | 1 |
| Kulig, KW | 1 |
| Stine, RJ | 1 |
| Slosberg, B | 1 |
| Beacham, BE | 1 |
| Gosselin, RE | 1 |
| Wananukul, W | 1 |
| Kaojarern, S | 1 |
| van Heijst, AN | 1 |
| Douze, JM | 1 |
| van Kesteren, RG | 1 |
| van Bergen, JE | 1 |
| van Dijk, A | 1 |
| Berlin, CM | 1 |
1 trial available for thiosulfates and Methemoglobinemia
| Article | Year |
|---|---|
Sodium thiosulfate fails to reduce nitrite-induced methemoglobinemia in vitro.
Topics: Antioxidants; Area Under Curve; Humans; In Vitro Techniques; Methemoglobinemia; Prospective Studies; | 2003 |
10 other studies available for thiosulfates and Methemoglobinemia
| Article | Year |
|---|---|
Pediatric cyanide poisoning by fire smoke inhalation: a European expert consensus. Toxicology Surveillance System of the Intoxications Working Group of the Spanish Society of Paediatric Emergencies.
Topics: 4-Aminopyridine; Age Factors; Algorithms; Antidotes; Child; Child, Preschool; Cyanides; Disease Mana | 2013 |
The role of cyanide liberation in the acute toxicity of aliphatic nitriles.
Topics: Animals; Biotransformation; Carbon Tetrachloride; Cyanides; Cytochrome c Group; Lethal Dose 50; Male | 1981 |
Effect of chlorpromazine on cyanide intoxication.
Topics: Animals; Antidotes; Brain; Chlorpromazine; Cyanides; Drug Synergism; Electron Transport Complex IV; | 1983 |
[Studies of sulfhemoglobin formation by various drugs (4). Influences of various antidotes on chemically induced methemoglobinemia and sulfhemoglobinemia (author's transl)].
Topics: Aniline Compounds; Animals; Ascorbic Acid; Ergothioneine; Glutathione; Male; Methemoglobinemia; Meth | 1980 |
Cyanide and methemoglobin kinetics in smoke inhalation victims treated with the cyanide antidote kit.
Topics: Adult; Antidotes; Carbon Monoxide Poisoning; Carboxyhemoglobin; Combined Modality Therapy; Cyanides; | 1993 |
Hydrogen sulfide intoxication. A case report and discussion of treatment.
Topics: Accidents, Occupational; Acidosis; Amyl Nitrite; Electron Transport Complex IV; Humans; Hydrogen Sul | 1976 |
Hydrogen sulfide poisoning.
Topics: Animals; Cyanides; Humans; Hydrogen Sulfide; Methemoglobinemia; Mice; Nitrites; Occupational Disease | 1979 |
Acute cyanide poisoning: a case report with toxicokinetic study.
Topics: Acute Disease; Adult; Antidotes; Humans; Male; Methemoglobinemia; Poisoning; Potassium Cyanide; Sodi | 1992 |
Therapeutic problems in cyanide poisoning.
Topics: Adult; Aminophenols; Coma; Cyanides; Humans; Male; Methemoglobinemia; Methylene Blue; Nitrites; Resp | 1987 |
The treatment of cyanide poisoning in children.
Topics: Cyanides; Electron Transport Complex IV; Hemoglobins; Humans; Infant; Male; Methemoglobin; Methemogl | 1970 |