thiosulfates has been researched along with Lupus Erythematosus, Systemic in 4 studies
Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this case series, we retrospectively identified all patients treated with topical sodium thiosulfate (TST) for calcinosis cutis (CC) associated with underlying autoimmune connective tissue diseases at Mayo Clinic (Rochester, MN, USA) during the period 1 January 2012 to 27 June 2017." | 7.91 | Topical sodium thiosulfate for calcinosis cutis associated with autoimmune connective tissue diseases: the Mayo Clinic experience, 2012-2017. ( Davis, MDP; Ernste, FC; Ma, JE; Wetter, DA, 2019) |
| "In this case series, we retrospectively identified all patients treated with topical sodium thiosulfate (TST) for calcinosis cutis (CC) associated with underlying autoimmune connective tissue diseases at Mayo Clinic (Rochester, MN, USA) during the period 1 January 2012 to 27 June 2017." | 3.91 | Topical sodium thiosulfate for calcinosis cutis associated with autoimmune connective tissue diseases: the Mayo Clinic experience, 2012-2017. ( Davis, MDP; Ernste, FC; Ma, JE; Wetter, DA, 2019) |
| "Non-uremic calciphylaxis is a rare, life-threatening condition characterized clinically by cutaneous necrosis and histologically by calcium deposition in small vessel walls." | 1.51 | Non-uremic calciphylaxis in a patient with multiple rheumatologic diseases. ( Cotter, D; Hinds, B; Kusari, A; Paravar, T, 2019) |
| "Sodium thiosulfate (STS) is used to treat calciphylaxis and cyanide poisoning, but can lead to a serious anion-gap acidosis." | 1.40 | Falsely increased chloride and missed anion gap elevation during treatment with sodium thiosulfate. ( Bachmann, LM; Boyd, JC; Bruns, DE; Haverstick, DM; Heady, TN; Scott, MG; Wendroth, SM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, JE | 1 |
| Ernste, FC | 1 |
| Davis, MDP | 1 |
| Wetter, DA | 1 |
| Kusari, A | 1 |
| Cotter, D | 1 |
| Hinds, B | 1 |
| Paravar, T | 1 |
| Wendroth, SM | 1 |
| Heady, TN | 1 |
| Haverstick, DM | 1 |
| Bachmann, LM | 1 |
| Scott, MG | 1 |
| Boyd, JC | 1 |
| Bruns, DE | 1 |
| Wolf, EK | 1 |
| Smidt, AC | 1 |
| Laumann, AE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study to Evaluate Topical Sodium Thiosulfate Therapy for Calcinosis Cutis (STS-CALC)[NCT01918904] | Phase 2 | 0 participants (Actual) | Interventional | 2013-09-30 | Withdrawn (stopped due to PI decided not to proceed with this project. No participants were enrolled.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for thiosulfates and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Topical sodium thiosulfate for calcinosis cutis associated with autoimmune connective tissue diseases: the Mayo Clinic experience, 2012-2017.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Juvenile; Arthriti | 2019 |
Non-uremic calciphylaxis in a patient with multiple rheumatologic diseases.
Topics: Calciphylaxis; Chelating Agents; Female; Humans; Kidney; Leg Ulcer; Lupus Erythematosus, Systemic; M | 2019 |
Falsely increased chloride and missed anion gap elevation during treatment with sodium thiosulfate.
Topics: Acid-Base Equilibrium; Adult; Calciphylaxis; Chlorides; Electrodes; False Positive Reactions; Female | 2014 |
Topical sodium thiosulfate therapy for leg ulcers with dystrophic calcification.
Topics: Administration, Topical; Adult; Calcinosis; Female; Humans; Immunosuppressive Agents; Leg Ulcer; Lup | 2008 |