thiosulfates has been researched along with Leg Ulcer in 14 studies
Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Knowledge of advancement in the treatment of calciphylaxis, which was previously a highly fatal disease, is important for physicians and other professionals from various medical fields." | 2.61 | Successful treatment of extensive uremic calciphylaxis with intravenous sodium thiosulfate and its potential in treating various diseases of pathologic calcification. ( Breznik, V; Burja, S; Ekart, R; Jovic, A; Miljkovic, J; Piko, N, 2019) |
| " Careful monitoring for adverse transient side effects is advised." | 2.50 | Successful treatment of calciphylaxis with intravenous sodium thiosulfate in a nonuremic patient: case report and review of therapy side effects. ( Fernandes, C; Hanna, D; Maynard, B, 2014) |
| "Sodium thiosulfate therapy has proven to be effective and tolerated." | 1.51 | Multifaceted approach to a rare clinical case of calciphylaxis in a renal transplant recipient. ( Bellasi, A; Feriozzi, S; Gomes, V; Massimetti, C; Modoni, A, 2019) |
| "Non-uremic calciphylaxis is a rare, life-threatening condition characterized clinically by cutaneous necrosis and histologically by calcium deposition in small vessel walls." | 1.51 | Non-uremic calciphylaxis in a patient with multiple rheumatologic diseases. ( Cotter, D; Hinds, B; Kusari, A; Paravar, T, 2019) |
| "Treatment with sodium thiosulfate was given for 8 patients, and was beneficial for all after a mean duration of 3." | 1.40 | [Incidence and characteristics of calciphylaxis in Martinique (2006-2012)]. ( Aoun, A; Banydeen, R; Baubion, E; Derancourt, C; Djiconkpode, I; Dueymes, JM; Ekindi, N; Quist, D; Riaux, A; Sadreux, T; Ureña-Torres, P, 2014) |
| " Although many recent case reports have shown exceptional results and healing with the use of sodium thiosulphate, we did not experience any change in the poor prognosis of our patients with the use of this drug, at a dosage of 5 g thrice weekly endovenously." | 1.39 | Calciphylaxis in dialysis patients, a severe disease poorly responding to therapies: report of 4 cases. ( Aldi, M; Cantelli, S; Gaddoni, G; Misciali, C; Odorici, G; Patrizi, A; Savoia, F; Tampieri, E; Tampieri, G, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massimetti, C | 1 |
| Bellasi, A | 1 |
| Modoni, A | 1 |
| Gomes, V | 1 |
| Feriozzi, S | 1 |
| Isoherranen, K | 1 |
| Bouchard, L | 1 |
| Kluger, N | 1 |
| Deverapalli, SC | 1 |
| Jacob, J | 1 |
| Santoro, F | 1 |
| Devey, S | 1 |
| Valois, A | 1 |
| Cazajous, G | 1 |
| Beaume, J | 1 |
| Abed, S | 1 |
| Okhremchuk, I | 1 |
| Spadoni, S | 1 |
| Boyé, T | 1 |
| Morand, JJ | 1 |
| Kusari, A | 1 |
| Cotter, D | 1 |
| Hinds, B | 1 |
| Paravar, T | 1 |
| Burja, S | 1 |
| Jovic, A | 1 |
| Ekart, R | 1 |
| Piko, N | 1 |
| Miljkovic, J | 1 |
| Breznik, V | 1 |
| Savoia, F | 1 |
| Gaddoni, G | 1 |
| Patrizi, A | 1 |
| Misciali, C | 1 |
| Odorici, G | 1 |
| Tampieri, G | 1 |
| Tampieri, E | 1 |
| Cantelli, S | 1 |
| Aldi, M | 1 |
| Hawkes, JE | 1 |
| Karavan, M | 1 |
| Bowen, AR | 1 |
| Summers, EM | 1 |
| Fernandes, C | 1 |
| Maynard, B | 1 |
| Hanna, D | 1 |
| Aoun, A | 1 |
| Baubion, E | 1 |
| Banydeen, R | 1 |
| Djiconkpode, I | 1 |
| Ekindi, N | 1 |
| Ureña-Torres, P | 1 |
| Riaux, A | 2 |
| Sadreux, T | 1 |
| Dueymes, JM | 1 |
| Quist, D | 1 |
| Derancourt, C | 2 |
| Wolf, EK | 1 |
| Smidt, AC | 1 |
| Laumann, AE | 1 |
| Ong, S | 1 |
| Coulson, IH | 1 |
| Baker, BL | 1 |
| Fitzgibbons, CA | 1 |
| Buescher, LS | 1 |
| Ackermann, F | 1 |
| Levy, A | 1 |
| Daugas, E | 1 |
| Schartz, N | 1 |
| Urena, P | 1 |
| Lebbé, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study to Evaluate Topical Sodium Thiosulfate Therapy for Calcinosis Cutis (STS-CALC)[NCT01918904] | Phase 2 | 0 participants (Actual) | Interventional | 2013-09-30 | Withdrawn (stopped due to PI decided not to proceed with this project. No participants were enrolled.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thiosulfates and Leg Ulcer
| Article | Year |
|---|---|
Successful treatment of extensive uremic calciphylaxis with intravenous sodium thiosulfate and its potential in treating various diseases of pathologic calcification.
Topics: Aged; Calciphylaxis; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Kidney Failure, Chro | 2019 |
Successful treatment of calciphylaxis with intravenous sodium thiosulfate in a nonuremic patient: case report and review of therapy side effects.
Topics: Administration, Intravenous; Calciphylaxis; Chelating Agents; Female; Humans; Leg Ulcer; Middle Aged | 2014 |
12 other studies available for thiosulfates and Leg Ulcer
| Article | Year |
|---|---|
Multifaceted approach to a rare clinical case of calciphylaxis in a renal transplant recipient.
Topics: Aged; Anticoagulants; Bone Density Conservation Agents; Calciphylaxis; Chelating Agents; Combined Mo | 2019 |
Benefits of intralesional injections of sodium thiosulfate in the treatment of calciphylaxis.
Topics: Aged; Aged, 80 and over; Antidotes; Calciphylaxis; Female; Humans; Injections, Intralesional; Leg Ul | 2017 |
Recalcitrant ulcer on the lower leg.
Topics: Administration, Intravenous; Aged, 80 and over; Antioxidants; Biopsy; Calciphylaxis; Diagnosis, Diff | 2017 |
[Calciphylaxis in hemodialysis patients: 8 cases treated with sodium thiosulfate].
Topics: Aged; Aged, 80 and over; Calciphylaxis; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diabet | 2018 |
Non-uremic calciphylaxis in a patient with multiple rheumatologic diseases.
Topics: Calciphylaxis; Chelating Agents; Female; Humans; Kidney; Leg Ulcer; Lupus Erythematosus, Systemic; M | 2019 |
Calciphylaxis in dialysis patients, a severe disease poorly responding to therapies: report of 4 cases.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Biopsy; Calciphylaxis; Cinacalcet; Combined Modality | 2013 |
Nonuraemic calciphylaxis and pancreatic cancer: a previously unreported association.
Topics: Adenocarcinoma; Administration, Oral; Aged; Calciphylaxis; Chelating Agents; Fatal Outcome; Humans; | 2014 |
[Incidence and characteristics of calciphylaxis in Martinique (2006-2012)].
Topics: Amputation, Surgical; Calciphylaxis; Female; Humans; Hyperparathyroidism, Secondary; Incidence; Kidn | 2014 |
Topical sodium thiosulfate therapy for leg ulcers with dystrophic calcification.
Topics: Administration, Topical; Adult; Calcinosis; Female; Humans; Immunosuppressive Agents; Leg Ulcer; Lup | 2008 |
Normo-renal calciphylaxis: response to sodium thiosulfate.
Topics: Aged; Calciphylaxis; Chelating Agents; Disease Progression; Female; Humans; Kidney; Leg Ulcer; Thios | 2011 |
Calciphylaxis responding to sodium thiosulfate therapy.
Topics: Aged; Calciphylaxis; Chelating Agents; Female; Humans; Leg Ulcer; Thiosulfates | 2007 |
Sodium thiosulfate as first-line treatment for calciphylaxis.
Topics: Calciphylaxis; Diabetes Complications; Female; Humans; Kidney Diseases; Kidney Transplantation; Leg | 2007 |