thiosulfates has been researched along with Disease Models, Animal in 29 studies
Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nephrolithiasis is one of the most common urinary tract disorders, with the majority of kidney stones composed of calcium oxalate (CaOx)." | 7.83 | Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis. ( Anderson, JB; Cabrero, P; Dow, JA; Gallo, CJ; Hirata, T; Landry, GM; Romero, MF, 2016) |
| " Sodium thiosulfate (STS) due to its multiple properties such as antioxidant and calcium chelation has been reported to prevent vascular calcification in uremic rats, without mentioning its impact on cerebral function." | 7.81 | Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification. ( Kurian, GA; Sriram, R; Subhash, N, 2015) |
| "The influence of sodium thiosulfate (STS) on the process of experimental acute pancreatitis (EAP) in rats was studied by cytomorphology, morphometry, autoradiography and cytophotometry." | 7.68 | [Cytological research on the action of sodium thiosulfate on the process of induced acute pancreatitis in rats]. ( Araratian, LA; Gabriélian, NA; Kanaian, AS; Karalova, EM; Magakian, IuA, 1990) |
| "Sodium thiosulfate (STS) is a U." | 5.35 | The effect of sodium thiosulfate administration on nephrocalcinosis in a rat model. ( LaGrange, CA; Lele, SM; Pais, VM, 2009) |
| "Nephrolithiasis is one of the most common urinary tract disorders, with the majority of kidney stones composed of calcium oxalate (CaOx)." | 3.83 | Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis. ( Anderson, JB; Cabrero, P; Dow, JA; Gallo, CJ; Hirata, T; Landry, GM; Romero, MF, 2016) |
| " Sodium thiosulfate (STS) due to its multiple properties such as antioxidant and calcium chelation has been reported to prevent vascular calcification in uremic rats, without mentioning its impact on cerebral function." | 3.81 | Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification. ( Kurian, GA; Sriram, R; Subhash, N, 2015) |
| "Sodium thiosulfate failed to reverse cyanide-induced shock in our swine model of severe cyanide toxicity." | 3.78 | Hydroxocobalamin versus sodium thiosulfate for the treatment of acute cyanide toxicity in a swine (Sus scrofa) model. ( Bebarta, VS; Bush, A; Dixon, P; Lairet, JR; Pitotti, RL; Tanen, DA, 2012) |
| "Hydroxocobalamin with sodium thiosulfate led to a faster return to baseline mean arterial pressure compared with sodium nitrite with sodium thiosulfate; however, there was no difference between the antidote combinations in mortality, serum acidosis, or serum lactate." | 3.76 | Hydroxocobalamin and sodium thiosulfate versus sodium nitrite and sodium thiosulfate in the treatment of acute cyanide toxicity in a swine (Sus scrofa) model. ( Bebarta, VS; Bush, A; Dixon, PS; Lairet, J; Tanen, DA; Valtier, S, 2010) |
| "The influence of sodium thiosulfate (STS) on the process of experimental acute pancreatitis (EAP) in rats was studied by cytomorphology, morphometry, autoradiography and cytophotometry." | 3.68 | [Cytological research on the action of sodium thiosulfate on the process of induced acute pancreatitis in rats]. ( Araratian, LA; Gabriélian, NA; Kanaian, AS; Karalova, EM; Magakian, IuA, 1990) |
| "Calciphylaxis is a rare but devastating condition that has continued to challenge the medical community since its early descriptions in the scientific literature many decades ago." | 2.52 | Calciphylaxis: risk factors, diagnosis, and treatment. ( Goverman, J; Jackson, VA; Kamdar, MM; Kroshinsky, D; Malhotra, R; Nazarian, RM; Nigwekar, SU; Steele, DJ; Thadhani, RI, 2015) |
| "Prenatal treatment of Down syndrome fetuses is also suggested." | 1.51 | Mental retardation in Down syndrome: Two ways to treat. ( Kamoun, PP, 2019) |
| "Sodium thiosulfate (STS) has of late been proven efficacious in models of urolithiasis and vascular calcification." | 1.46 | Sodium Thiosulfate Preconditioning Ameliorates Ischemia/Reperfusion Injury in Rat Hearts Via Reduction of Oxidative Stress and Apoptosis. ( Boovarahan, SR; Kurian, GA; Ravindran, S; Shanmugam, K; Vedarathinam, RC, 2017) |
| "Hydrogen sulfide (H2S) is an endogenously produced gasotransmitter with cardioprotective properties." | 1.42 | Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats. ( de Boer, RA; Frenay, AR; Hillebrands, JL; Leuvenink, HG; Pasch, A; Snijder, PM; van Goor, H, 2015) |
| "Hyperoxaluria causes crystal deposition in the kidney, which leads to oxidative stress and to injury and damage of the renal epithelium." | 1.42 | Sodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric rats. ( Bachtler, M; Bijarnia, RK; Chandak, PG; Pasch, A; van Goor, H, 2015) |
| "Sodium thiosulfate (STS) is a U." | 1.35 | The effect of sodium thiosulfate administration on nephrocalcinosis in a rat model. ( LaGrange, CA; Lele, SM; Pais, VM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.34) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 16 (55.17) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Kamoun, PP | 1 |
| Ravindran, S | 3 |
| Gopalakrishnan, S | 1 |
| Kurian, GA | 4 |
| Schulz, J | 1 |
| Kramer, S | 1 |
| Kanatli, Y | 1 |
| Kuebart, A | 1 |
| Bauer, I | 1 |
| Picker, O | 1 |
| Vollmer, C | 1 |
| Truse, R | 1 |
| Herminghaus, A | 1 |
| Daeffler, KN | 1 |
| Galley, JD | 1 |
| Sheth, RU | 1 |
| Ortiz-Velez, LC | 1 |
| Bibb, CO | 1 |
| Shroyer, NF | 1 |
| Britton, RA | 1 |
| Tabor, JJ | 1 |
| Boovarahan, SR | 1 |
| Shanmugam, K | 1 |
| Vedarathinam, RC | 1 |
| Ng, PC | 1 |
| Hendry-Hofer, TB | 1 |
| Witeof, AE | 1 |
| Mahon, SB | 2 |
| Brenner, M | 2 |
| Boss, GR | 2 |
| Bebarta, VS | 4 |
| Shirozu, K | 1 |
| Tokuda, K | 1 |
| Marutani, E | 1 |
| Lefer, D | 1 |
| Wang, R | 1 |
| Ichinose, F | 1 |
| Snijder, PM | 1 |
| Frenay, AR | 1 |
| de Boer, RA | 1 |
| Pasch, A | 2 |
| Hillebrands, JL | 1 |
| Leuvenink, HG | 1 |
| van Goor, H | 2 |
| Bijarnia, RK | 1 |
| Bachtler, M | 1 |
| Chandak, PG | 1 |
| Nigwekar, SU | 1 |
| Kroshinsky, D | 1 |
| Nazarian, RM | 1 |
| Goverman, J | 1 |
| Malhotra, R | 1 |
| Jackson, VA | 1 |
| Kamdar, MM | 1 |
| Steele, DJ | 1 |
| Thadhani, RI | 1 |
| Subhash, N | 1 |
| Sriram, R | 1 |
| Landry, GM | 1 |
| Hirata, T | 1 |
| Anderson, JB | 1 |
| Cabrero, P | 1 |
| Gallo, CJ | 1 |
| Dow, JA | 1 |
| Romero, MF | 1 |
| Brittain, M | 1 |
| Chan, A | 1 |
| Garrett, N | 1 |
| Yoon, D | 1 |
| Burney, T | 1 |
| Mukai, D | 1 |
| Babin, M | 1 |
| Pilz, RB | 1 |
| LaGrange, CA | 1 |
| Lele, SM | 1 |
| Pais, VM | 1 |
| Ghesquière, B | 1 |
| Colaert, N | 1 |
| Helsens, K | 1 |
| Dejager, L | 1 |
| Vanhaute, C | 1 |
| Verleysen, K | 1 |
| Kas, K | 1 |
| Timmerman, E | 1 |
| Goethals, M | 1 |
| Libert, C | 1 |
| Vandekerckhove, J | 1 |
| Gevaert, K | 1 |
| Tanen, DA | 2 |
| Lairet, J | 1 |
| Dixon, PS | 1 |
| Valtier, S | 1 |
| Bush, A | 2 |
| O'Neill, WC | 1 |
| Lomashvili, KA | 1 |
| Pitotti, RL | 1 |
| Dixon, P | 1 |
| Lairet, JR | 1 |
| Di Meo, I | 1 |
| Auricchio, A | 1 |
| Lamperti, C | 1 |
| Burlina, A | 1 |
| Viscomi, C | 1 |
| Zeviani, M | 1 |
| Leitao, DJ | 1 |
| Blakley, BW | 3 |
| Viallet, NR | 1 |
| Begleiter, A | 1 |
| Leith, MK | 1 |
| Hochman, J | 1 |
| Wellman, M | 1 |
| Blakley, L | 1 |
| Nagata, T | 1 |
| Kage, S | 1 |
| Kimura, K | 1 |
| Kudo, K | 1 |
| Imamura, T | 1 |
| Graeme, KA | 1 |
| Curry, SC | 1 |
| Bikin, DS | 1 |
| Lo Vecchio, FA | 1 |
| Brandon, TA | 1 |
| Michenfelder, JD | 1 |
| Tinker, JH | 1 |
| Karalova, EM | 1 |
| Kanaian, AS | 1 |
| Araratian, LA | 1 |
| Gabriélian, NA | 1 |
| Magakian, IuA | 1 |
| Fenske, A | 1 |
| Samii, M | 1 |
| Reulen, HJ | 1 |
| Hey, O | 1 |
| Raab, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Partners Calciphylaxis Biobank and Patient Registry[NCT03032835] | 300 participants (Anticipated) | Observational [Patient Registry] | 2017-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thiosulfates and Disease Models, Animal
| Article | Year |
|---|---|
Calciphylaxis: risk factors, diagnosis, and treatment.
Topics: Animals; Arterioles; Biopsy; Calciphylaxis; Case-Control Studies; Chronic Kidney Disease-Mineral and | 2015 |
Recent progress in the treatment of vascular calcification.
Topics: Animals; Calcinosis; Diphosphonates; Disease Models, Animal; Humans; Kidney Diseases; Thiosulfates; | 2010 |
27 other studies available for thiosulfates and Disease Models, Animal
| Article | Year |
|---|---|
Mental retardation in Down syndrome: Two ways to treat.
Topics: Aminooxyacetic Acid; Animals; Benserazide; Brain; Chromosomes, Human, Pair 21; Cobamides; Cystathion | 2019 |
Beneficial effect of sodium thiosulfate extends beyond myocardial tissue in isoproterenol model of infarction: Implication for nootropic effects.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Heart; Hydrogen Sulfide; Isoproterenol; Male; Mit | 2020 |
Sodium Thiosulfate Improves Intestinal and Hepatic Microcirculation Without Affecting Mitochondrial Function in Experimental Sepsis.
Topics: Animals; Antioxidants; Colon; Disease Models, Animal; Liver; Male; Microcirculation; Mitochondria; R | 2021 |
Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation.
Topics: Animals; Bacterial Proteins; Biosensing Techniques; Colitis; Colon; Disease Models, Animal; Feces; G | 2017 |
Sodium Thiosulfate Preconditioning Ameliorates Ischemia/Reperfusion Injury in Rat Hearts Via Reduction of Oxidative Stress and Apoptosis.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Cell Line; Disease Models, Animal; Dose-Response | 2017 |
Effect of Sodium Thiosulfate Postconditioning on Ischemia-Reperfusion Injury Induced Mitochondrial Dysfunction in Rat Heart.
Topics: Animals; Antioxidants; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Isolat | 2018 |
Efficacy of Oral Administration of Sodium Thiosulfate and Glycine in a Large, Swine Model of Oral Cyanide Toxicity.
Topics: Administration, Oral; Animals; Antidotes; Disease Models, Animal; Drug Therapy, Combination; Female; | 2019 |
Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure.
Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Cystathionine gamma-Lyase; Disease Models, Animal; Gal | 2014 |
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Anim | 2015 |
Sodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Hyperoxaluria; Kidney; Kidney Function Tests; Male; O | 2015 |
Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification.
Topics: Adenine; Animals; Antioxidants; Brain; Catalase; Disease Models, Animal; Glutathione Peroxidase; Kid | 2015 |
Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis.
Topics: Animals; Anion Transport Proteins; Antiporters; Calcium Oxalate; Disease Models, Animal; Drosophila | 2016 |
Sodium Nitrite and Sodium Thiosulfate Are Effective Against Acute Cyanide Poisoning When Administered by Intramuscular Injection.
Topics: Animals; Antidotes; Cyanides; Disease Models, Animal; Injections, Intramuscular; Male; Mice; Rabbits | 2017 |
The effect of sodium thiosulfate administration on nephrocalcinosis in a rat model.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Kidney; Male; Nephrocalcinosis; Radiography; Rats; | 2009 |
In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography.
Topics: Amino Acid Sequence; Animals; Blood Proteins; Cattle; Cell Extracts; Chromatography, High Pressure L | 2009 |
Hydroxocobalamin and sodium thiosulfate versus sodium nitrite and sodium thiosulfate in the treatment of acute cyanide toxicity in a swine (Sus scrofa) model.
Topics: Acidosis; Animals; Antidotes; Blood Pressure; Cyanides; Disease Models, Animal; Drug Therapy, Combin | 2010 |
Hydroxocobalamin versus sodium thiosulfate for the treatment of acute cyanide toxicity in a swine (Sus scrofa) model.
Topics: Animals; Antidotes; Blood Pressure; Cyanides; Disease Models, Animal; Drug Therapy, Combination; Fem | 2012 |
Effective AAV-mediated gene therapy in a mouse model of ethylmalonic encephalopathy.
Topics: Animals; Brain Diseases, Metabolic, Inborn; Dependovirus; Dioxygenases; Disease Models, Animal; Gene | 2012 |
Quantification of sodium thiosulphate protection on cisplatin-induced toxicities.
Topics: Animals; Antidotes; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Dose-Response Relation | 2003 |
Effect of sodium thiosulphate and cis-diamminedichloroplatinum on FADU tumour cells in nude mice.
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Squamous Cell; Cisplatin; Disease Models, A | 2005 |
Prevention of aminoglycoside-induced sensorineural hearing loss.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Disease Models, Animal; Drug Resistance; Evoked Potent | 2006 |
How to diagnose polysulphide poisoning from tissue samples.
Topics: Animals; Calcium Compounds; Cause of Death; Chromatography, Gas; Clinical Protocols; Disease Models, | 1994 |
The lack of transplacental movement of the cyanide antidote thiosulfate in gravid ewes.
Topics: Animals; Antidotes; Antihypertensive Agents; Cyanides; Disease Models, Animal; Female; Fetal Blood; | 1999 |
Cyanide toxicity and thiosulfate protection during chronic administration of sodium nitroprusside in the dog: correlation with a human case.
Topics: Adolescent; Animals; Blood Pressure; Cyanides; Disease Models, Animal; Dogs; Dose-Response Relations | 1977 |
[Cytological research on the action of sodium thiosulfate on the process of induced acute pancreatitis in rats].
Topics: Acute Disease; Animals; Autoradiography; Cytophotometry; Disease Models, Animal; Drug Evaluation, Pr | 1990 |
Extracellular space and electrolyte distribution in cortex and white matter of dog brain in cold induced oedema.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Cortex; Chlorides; Cold Temperature; Disease Mod | 1973 |
[Effect of L-ornithin-L-aspartate on toxic kidney disorders similar to nephrosis].
Topics: Animals; Aspartic Acid; Disease Models, Animal; Male; Nephrosis; Ornithine; Rats; Thiosulfates | 1972 |