thiosulfates has been researched along with Cancer of Ovary in 29 studies
Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a phase II trial of intraperitoneal (IP) cisplatin (DDP) and etoposide (VP-16) in stage III and IV newly diagnosed ovarian carcinoma patients with residual disease of any size." | 3.68 | A phase II trial of intraperitoneal cisplatin and etoposide for primary treatment of ovarian epithelial cancer. ( Goel, R; Horton, MC; Howell, SB; Kim, S; Kirmani, S; Lucas, WE; McVey, L; Morris, J; Weiss, RJ; Zimm, S, 1990) |
| "As in many ovarian cancer patients the disease remains confined to the peritoneal cavity, intraperitoneal (i." | 2.68 | Experience with intraperitoneal cisplatin and etoposide and i.v. sodium thiosulphate protection in ovarian cancer patients with either pathologically complete response or minimal residual disease. ( Burger, CW; Hoekman, K; van Rijswijk, RE; Verheijen, RH; Vermorken, JB, 1997) |
| "We conclude that the French ovarian cancer protocol may represent a significant advance and that glucose potentiation may be more widely applicable as an adjunct to cancer chemotherapy." | 2.67 | Glucose effects in an ovarian cancer protocol of exceptional activity. ( Lin, JY; Scheim, DE, 1993) |
| "Sodium thiosulfate was given as an intravenous antidote to cisplatin." | 2.67 | Intraperitoneal high-dose cisplatin and etoposide with systemic thiosulfate protection in second-line treatment of advanced ovarian cancer. ( Malmström, H; Rasmussen, S; Simonsen, E, 1993) |
| "Ovarian carcinoma demonstrates a steep dose-response curve for cisplatin, but even very small levels of acquired resistance at the cellular level are sufficient to block the efficacy of intravenous (IV) cisplatin." | 2.38 | Intraperitoneal cisplatin-based chemotherapy for ovarian carcinoma. ( Braly, P; Howell, SB; Kim, S; Kirmani, S; McClay, EF; Plaxe, S, 1991) |
| "These patients included those with ovarian cancer (3 cases), metastatic ovarian cancer (1 case), and endometrial cancer (1 case)." | 1.27 | [Treatment of gynecological cancer with cis-platinum]. ( Mano, T; Miyake, T; Nakamura, Y; Saito, T; Takeshima, N; Tomimatsu, T, 1987) |
| "Treatment of patients with advanced ovarian cancer who have failure of first-line chemotherapy is rarely effective." | 1.27 | Intraperitoneal chemotherapy for advanced ovarian cancer. ( Howell, SB; Lucas, WE; Markman, M, 1985) |
| "Sodium thiosulfate was shown to protect renal function, as well as lessen hematologic complications of cisplatin therapy." | 1.27 | Experimental and clinical results with intraperitoneal cisplatin. ( Aartsen, E; Dubbelman, R; Franklin, H; McVie, JG; ten Bokkel Huinink, WW, 1985) |
| "Sodium thiosulfate has been shown experimentally to protect against cisplatin-induced renal insufficiency by inactivating the nephrotoxic as well as cytotoxic properties of the agent." | 1.27 | Nephrotoxicity of high-dose intracavitary cisplatin with intravenous thiosulfate protection. ( Cleary, S; Howell, SB; Markman, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (51.72) | 18.7374 |
| 1990's | 13 (44.83) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Senguttuvan, RN | 1 |
| Santiago, NL | 1 |
| Han, ES | 1 |
| Lee, B | 1 |
| Lee, S | 1 |
| Lin, WC | 1 |
| Kebria, M | 1 |
| Hakim, A | 1 |
| Lin, JF | 1 |
| Wakabayashi, MT | 1 |
| Ruel, N | 1 |
| Tinsley, R | 1 |
| Eng, M | 1 |
| Stewart, DB | 1 |
| Wang, EW | 1 |
| Paz, BI | 1 |
| Wu, X | 1 |
| Cho, H | 1 |
| Liang, WS | 1 |
| Rodriguez-Rodriguez, L | 1 |
| Cristea, MC | 1 |
| Raoof, M | 1 |
| Dellinger, TH | 1 |
| Hatae, M | 2 |
| Tezuka, H | 1 |
| Ushiki, N | 1 |
| Ezono, Y | 1 |
| Igyuin, H | 1 |
| Terahara, M | 1 |
| Hokanishi, H | 1 |
| Howell, SB | 7 |
| Pfeifle, CE | 2 |
| Wung, WE | 1 |
| Olshen, RA | 1 |
| de Jong, RS | 1 |
| Willemse, PH | 1 |
| Boonstra, H | 1 |
| de Vries, EG | 1 |
| van der Graaf, WT | 1 |
| Sleijfer, DT | 1 |
| van der Zee, AG | 1 |
| Mulder, NH | 1 |
| Scheim, DE | 1 |
| Lin, JY | 1 |
| Ben-Baruch, G | 3 |
| Menczer, J | 3 |
| Feldman, B | 1 |
| Rizel, S | 3 |
| Brenner, H | 3 |
| Guastalla, JP | 1 |
| Vermorken, JB | 2 |
| Wils, JA | 1 |
| George, M | 1 |
| Scotto, V | 1 |
| Nooij, M | 1 |
| ten Bokkel Huinnink, WW | 1 |
| Dalesio, O | 1 |
| Renard, J | 1 |
| Malmström, H | 1 |
| Rasmussen, S | 1 |
| Simonsen, E | 1 |
| van Rijswijk, RE | 1 |
| Hoekman, K | 1 |
| Burger, CW | 1 |
| Verheijen, RH | 1 |
| Takizawa, K | 3 |
| Harada, M | 2 |
| Fujimaru, J | 2 |
| Matsushiro, N | 1 |
| Shima, Y | 2 |
| Andoh, I | 1 |
| Satoh, M | 1 |
| Yokoo, I | 2 |
| Iguchi, T | 3 |
| Hirabayashi, K | 1 |
| Kirmani, S | 2 |
| McClay, EF | 1 |
| Kim, S | 2 |
| Braly, P | 1 |
| Plaxe, S | 1 |
| Abe, R | 1 |
| Akiyoshi, T | 1 |
| Baba, T | 1 |
| Lucas, WE | 2 |
| Zimm, S | 1 |
| Goel, R | 1 |
| Horton, MC | 1 |
| McVey, L | 1 |
| Morris, J | 1 |
| Weiss, RJ | 1 |
| Ozaki, I | 1 |
| Sato, M | 2 |
| Takeda, Y | 2 |
| Canal, P | 1 |
| de Forni, M | 1 |
| Chatelut, E | 1 |
| Chevreau, C | 1 |
| Johnson, NP | 1 |
| Houin, G | 1 |
| Bugat, R | 1 |
| Markman, M | 4 |
| Cleary, S | 3 |
| Ino, Y | 1 |
| Isono, T | 1 |
| Maruyama, M | 1 |
| Noda, T | 1 |
| Kiyozuka, Y | 1 |
| Oku, M | 1 |
| Ninomiya, Y | 1 |
| Ibaraki, T | 1 |
| Katoh, Y | 1 |
| Itani, Y | 1 |
| Okamura, Y | 1 |
| Beppu, K | 1 |
| Tateyama, I | 1 |
| Kamitani, N | 1 |
| Tominaga, T | 1 |
| Mori, T | 1 |
| Mano, T | 1 |
| Takeshima, N | 1 |
| Nakamura, Y | 1 |
| Tomimatsu, T | 1 |
| Saito, T | 1 |
| Miyake, T | 1 |
| Miyahara, K | 1 |
| Miyoshi, T | 1 |
| Kobayashi, H | 1 |
| Hamai, J | 1 |
| Tomoo, Y | 1 |
| Yamada, T | 1 |
| Nishimura, H | 1 |
| Yakushiji, M | 1 |
| Kato, T | 1 |
| ten Bokkel Huinink, WW | 1 |
| Dubbelman, R | 1 |
| Aartsen, E | 1 |
| Franklin, H | 1 |
| McVie, JG | 1 |
| Ozols, R | 1 |
1 review available for thiosulfates and Cancer of Ovary
| Article | Year |
|---|---|
Intraperitoneal cisplatin-based chemotherapy for ovarian carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Cisplatin; Etoposide; Female; Humans; | 1991 |
6 trials available for thiosulfates and Cancer of Ovary
| Article | Year |
|---|---|
Phase II study of intraperitoneal cisplatin plus systemic etoposide as second-line treatment in patients with small volume residual ovarian cancer.
Topics: Administration, Topical; Adult; Aged; Antioxidants; Cisplatin; Disease-Free Survival; Drug Therapy, | 1995 |
Glucose effects in an ovarian cancer protocol of exceptional activity.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cytarabine | 1993 |
Phase II trial for intraperitoneal cisplatin plus intravenous sodium thiosulphate in advanced ovarian carcinoma patients with minimal residual disease after cisplatin-based chemotherapy--a phase II study of the EORTC Gynaecological Cancer Cooperative Grou
Topics: Aged; Catheterization, Peripheral; Cisplatin; Female; Humans; Infusions, Parenteral; Kidney Diseases | 1994 |
Intraperitoneal high-dose cisplatin and etoposide with systemic thiosulfate protection in second-line treatment of advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Humans; I | 1993 |
Experience with intraperitoneal cisplatin and etoposide and i.v. sodium thiosulphate protection in ovarian cancer patients with either pathologically complete response or minimal residual disease.
Topics: Adult; Aged; Antidotes; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Prot | 1997 |
[The clinical and pharmacokinetic evaluation of two-route chemotherapy with cisplatin and sodium thiosulfate in combination with angiotensin II].
Topics: Angiotensin II; Blood Pressure; Cisplatin; Drug Therapy, Combination; Female; Humans; Ovarian Neopla | 1992 |
22 other studies available for thiosulfates and Cancer of Ovary
| Article | Year |
|---|---|
ASO Visual Abstract: Impact of Sodium Thiosulfate on Prevention of Nephrotoxicities in HIPEC: An Ancillary Evaluation of Cisplatin-Induced Toxicities in Ovarian Cancer.
Topics: Cisplatin; Cytoreduction Surgical Procedures; Female; Humans; Hyperthermia, Induced; Hyperthermic In | 2024 |
[Intraperitoneal and intrapleural two channel chemotherapy by cisplatinum (DDP) and sodium thiosulfate for the treatment of ovarian cancer].
Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cisplatin; Cystadenocarcinoma; Drug Therapy, Combin | 1984 |
Intraperitoneal cis-diamminedichloroplatinum with systemic thiosulfate protection.
Topics: Adult; Cell Division; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Evaluation; Drug | 1983 |
Intraperitoneal cisplatin chemotherapy versus abdominopelvic irradiation in ovarian carcinoma patients after second look laparotomy. A reassessment based on mature data.
Topics: Abdomen; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality The | 1994 |
Intraperitoneal cisplatin chemotherapy in ovarian carcinoma patients who are clinically in complete remission.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; H | 1992 |
Acute renal failure associated with intraperitoneal cisplatin chemotherapy with systemic thiosulfate protection in ovarian cancer patients.
Topics: Acute Kidney Injury; Cisplatin; Creatinine; Drug Administration Schedule; Female; Humans; Injections | 1991 |
'Two-route chemotherapy' using cisplatin and its neutralizing agent, sodium thiosulfate, for intraperitoneal cancer.
Topics: Adult; Aged; Animals; Antidotes; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Dogs; Female; Human | 1990 |
A phase II trial of intraperitoneal cisplatin and etoposide for primary treatment of ovarian epithelial cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Drug Evaluation; Etoposide; Fe | 1990 |
[The hypertensive effect induced with angiotensin II and the physiological and pharmacokinetic aspects of two-route chemotherapy using CDDP and STS].
Topics: Angiotensin II; Blood Pressure; Cisplatin; Drug Administration Schedule; Female; Humans; Infusions, | 1990 |
Clinical and pharmacokinetic study of intraperitoneal cisplatin at two dose levels: 100 mg/m2 alone or 200 mg/m2 with i.v. sodium thiosulfate.
Topics: Adenocarcinoma; Antidotes; Cisplatin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug T | 1989 |
High-dose intracavitary cisplatin with intravenous thiosulfate. Low incidence of serious neurotoxicity.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Ear Diseases; Fe | 1985 |
[The pharmacokinetics and clinical toxicities following intraperitoneal infusion of cis-diamminedichloroplatinum (II) with simultaneous sodium thiosulfate rescue in patients with ovarian cancer].
Topics: Antidotes; Cisplatin; Female; Humans; Ovarian Neoplasms; Thiosulfates | 1988 |
[A case report of advanced ovarian cancer with chronic renal dysfunction treated by CDDP i.p].
Topics: Cisplatin; Drug Administration Schedule; Female; Humans; Injections; Kidney Failure, Chronic; Middle | 1988 |
[Selective intra-arterial administration of CDDP in a malignant ovarian tumor with peculiar ultrastructural findings].
Topics: Adult; Cisplatin; Cystadenocarcinoma; Female; Humans; Infusions, Intra-Arterial; Ovarian Neoplasms; | 1988 |
[Treatment of gynecological cancer with cis-platinum].
Topics: Adenocarcinoma; Cisplatin; Female; Humans; Infusions, Intravenous; Middle Aged; Ovarian Neoplasms; R | 1987 |
[Pharmacokinetics of cisplatinum (CDDP) and sodium thiosulphate (STS) of intraperitoneal two channel chemotherapy (ip TCC) in man and mongrel dogs].
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dogs; Female; Humans; Inj | 1986 |
[An experimental study of cisplatin and it's antidote, sodium thiosulfate, in ovarian pseudomyxoma implanted into nude mice abdominal cavity].
Topics: Animals; Antidotes; Body Weight; Cisplatin; Cystadenoma; Female; Mice; Mice, Nude; Neoplasm Transpla | 1986 |
Hypomagnesemia following high-dose intracavitary cisplatin with systemically administered sodium thiosulfate.
Topics: Adult; Aged; Carcinoma; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases | 1986 |
Intraperitoneal chemotherapy for advanced ovarian cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubici | 1985 |
Experimental and clinical results with intraperitoneal cisplatin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catheterization; Catheters, Indwelling; Cisplatin; F | 1985 |
Intraperitoneal chemotherapy in the management of ovarian cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Cispla | 1985 |
Nephrotoxicity of high-dose intracavitary cisplatin with intravenous thiosulfate protection.
Topics: Acute Kidney Injury; Adult; Aged; Cisplatin; Creatinine; Female; Humans; Injections; Injections, Int | 1985 |