thiosemicarbazide and Nociceptive-Pain

thiosemicarbazide has been researched along with Nociceptive-Pain* in 1 studies

Other Studies

1 other study(ies) available for thiosemicarbazide and Nociceptive-Pain

Article	Year
Preliminary Pharmacological Screening of Some Thiosemicarbazide, s-triazole, and Thiadiazole Derivatives. CNS & neurological disorders drug targets, 2016, Volume: 15, Issue:6 Two thiosemicarbazide derivatives 1 and 2, three 2-amino-1,3,4-thiadiazole derivatives 3-5, and three N1- substituted-4-methyl-1,2,4-triazole-5-thione derivatives 6-8 were synthesized and evaluated for their central nervous system effects using rodent behavioral models. With the exception of 6, all compounds were devoid of neurotoxicity and they did not affect the body temperature of mice. New lead structures 1-4 with potential analgesic activity were identified. Topics: Analgesics; Animals; Anxiety; Body Temperature; Central Nervous System Agents; Depression; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Mice; Molecular Structure; Motor Activity; Nociceptive Pain; Seizures; Semicarbazides; Sleep; Thiadiazoles; Triazoles	2016

Article

Year

Preliminary Pharmacological Screening of Some Thiosemicarbazide, s-triazole, and Thiadiazole Derivatives.

CNS & neurological disorders drug targets, 2016, Volume: 15, Issue:6

Two thiosemicarbazide derivatives 1 and 2, three 2-amino-1,3,4-thiadiazole derivatives 3-5, and three N1- substituted-4-methyl-1,2,4-triazole-5-thione derivatives 6-8 were synthesized and evaluated for their central nervous system effects using rodent behavioral models. With the exception of 6, all compounds were devoid of neurotoxicity and they did not affect the body temperature of mice. New lead structures 1-4 with potential analgesic activity were identified.

Topics: Analgesics; Animals; Anxiety; Body Temperature; Central Nervous System Agents; Depression; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Mice; Molecular Structure; Motor Activity; Nociceptive Pain; Seizures; Semicarbazides; Sleep; Thiadiazoles; Triazoles

2016