thiosemicarbazide has been researched along with Leukemia-P388* in 1 studies
1 other study(ies) available for thiosemicarbazide and Leukemia-P388
| Article | Year |
|---|---|
Thiourea and thiosemicarbazide derivatives structurally related to hexestrol: synthesis and anticancer and other pharmacological properties.
Two novel series of thio compounds bearing internal structural modifications of hexestrol were synthesized as potential anticancer agents. The first contains several N-substituted thiourea functions, and the second contains various N4-substituted-3-thiosemicarbazide moieties in place of one alpha-ethyl group of hexestrol dimethyl ether. The products showed no antileukemic activity in the P-388 lymphocytic leukemia system and did not exhibit any anticonvulsant or estrogenic properties. Topics: Animals; Antineoplastic Agents; Hexestrol; Leukemia P388; Mice; Semicarbazides; Structure-Activity Relationship; Thiourea | 1981 |