thiosemicarbazide has been researched along with Leishmaniasis* in 1 studies
1 other study(ies) available for thiosemicarbazide and Leishmaniasis
| Article | Year |
|---|---|
Molecular hybridization conceded exceptionally potent quinolinyl-oxadiazole hybrids through phenyl linked thiosemicarbazide antileishmanial scaffolds: In silico validation and SAR studies.
The high potential of quinoline containing natural products and their derivatives in medicinal chemistry led us to discover a novel series of compounds 6-23 based on the concept of molecular hybridization. Most of the synthesized analogues exhibited potent leishmanicidal potential. The most potent compound (23, IC Topics: Animals; Antiprotozoal Agents; Cell Line; Chlorocebus aethiops; Drug Design; Humans; Leishmania; Leishmaniasis; Molecular Docking Simulation; Oxadiazoles; Oxidoreductases; Quinolines; Semicarbazides; Structure-Activity Relationship; Vero Cells | 2017 |