thiorphan has been researched along with Pulmonary Hypertension in 3 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A deficiency of the pulmonary vasodilative vasoactive intestinal peptide (VIP) has been suggested to be involved in the pathophysiology of pulmonary hypertension (PH)." | 7.81 | Augmentation of the effects of vasoactive intestinal peptide aerosol on pulmonary hypertension via coapplication of a neutral endopeptidase 24.11 inhibitor. ( Behr, J; Bevec, D; Callegari, J; Haziraj, S; Leuchte, HH; Meis, T; Prechtl, C, 2015) |
| "A deficiency of the pulmonary vasodilative vasoactive intestinal peptide (VIP) has been suggested to be involved in the pathophysiology of pulmonary hypertension (PH)." | 3.81 | Augmentation of the effects of vasoactive intestinal peptide aerosol on pulmonary hypertension via coapplication of a neutral endopeptidase 24.11 inhibitor. ( Behr, J; Bevec, D; Callegari, J; Haziraj, S; Leuchte, HH; Meis, T; Prechtl, C, 2015) |
| "To explore the roles of endogenous atrial natriuretic peptide (ANP) in the volume regulation, we examined effects of antiserum for ANP or a neutral endopeptidase inhibitor, thiorphan, in rats with monocrotaline (MCT)-induced pulmonary hypertension." | 3.68 | Role of endogenous ANP in sodium excretion in rats with experimental pulmonary hypertension. ( Hayakawa, H; Hirata, Y; Kangawa, K; Kojima, M; Matsuo, H; Matsuoka, H; Sugimoto, T; Suzuki, E, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leuchte, HH | 1 |
| Prechtl, C | 1 |
| Callegari, J | 1 |
| Meis, T | 1 |
| Haziraj, S | 1 |
| Bevec, D | 1 |
| Behr, J | 1 |
| Baliga, RS | 1 |
| Zhao, L | 1 |
| Madhani, M | 1 |
| Lopez-Torondel, B | 1 |
| Visintin, C | 1 |
| Selwood, D | 1 |
| Wilkins, MR | 1 |
| MacAllister, RJ | 1 |
| Hobbs, AJ | 1 |
| Hirata, Y | 1 |
| Suzuki, E | 1 |
| Hayakawa, H | 1 |
| Matsuoka, H | 1 |
| Sugimoto, T | 1 |
| Kojima, M | 1 |
| Kangawa, K | 1 |
| Matsuo, H | 1 |
3 other studies available for thiorphan and Pulmonary Hypertension
| Article | Year |
|---|---|
Augmentation of the effects of vasoactive intestinal peptide aerosol on pulmonary hypertension via coapplication of a neutral endopeptidase 24.11 inhibitor.
Topics: Administration, Inhalation; Animals; Blood Pressure; Hypertension, Pulmonary; Neprilysin; Protease I | 2015 |
Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Atrial Natriuretic Factor; Disease Models, Animal; Dru | 2008 |
Role of endogenous ANP in sodium excretion in rats with experimental pulmonary hypertension.
Topics: Animals; Atrial Natriuretic Factor; Hypertension, Pulmonary; Immune Sera; Male; Monocrotaline; Natri | 1992 |