thiorphan has been researched along with Pregnancy in 4 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of pregnancy on renal responses to atrial natriuretic factor (ANF) was determined in urethane-anesthetized Sprague-Dawley rats." | 7.69 | Attenuation of renal effects of atrial natriuretic factor during rat pregnancy. ( Cernacek, P; Mulay, S; Omer, S; Varma, DR, 1995) |
| "The effects of two enkephalinase inhibitors, acetorphan and thiorphan, and the enkephalin analogue [D-Ala2-Met5]-enkephalinamide (DAMEA), on spontaneous uterine contractions were studied at day 21 of pregnancy in rats following treatment in vivo or in vitro." | 3.69 | Peripheral excitatory effects of two enkephalinase inhibitors, acetorphan and thiorphan, and an enkephalin analogue, [D-Ala2-Met5]-enkephalinamide, on uterine motility in periparturient rats in vivo and in vitro. ( Adjroud, O, 1995) |
| "The influence of pregnancy on renal responses to atrial natriuretic factor (ANF) was determined in urethane-anesthetized Sprague-Dawley rats." | 3.69 | Attenuation of renal effects of atrial natriuretic factor during rat pregnancy. ( Cernacek, P; Mulay, S; Omer, S; Varma, DR, 1995) |
| "Ubenimex, which can inhibit several aminopeptidases, also reduced the liberated amino acids to about 50 per cent." | 1.31 | Possible involvement of placental peptidases that degrade gonadotropin-releasing hormone (GnRH) in the dynamic pattern of placental hCG secretion via GnRH degradation. ( Ino, K; Itakura, A; Ito, M; Kajiyama, H; Kikkawa, F; Mizutani, S; Nomura, S; Tsujimoto, M; Watanabe, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davies, J | 1 |
| Chant, R | 1 |
| Simpson, S | 1 |
| Powell, R | 1 |
| Kikkawa, F | 1 |
| Kajiyama, H | 1 |
| Ino, K | 1 |
| Watanabe, Y | 1 |
| Ito, M | 1 |
| Nomura, S | 1 |
| Itakura, A | 1 |
| Tsujimoto, M | 1 |
| Mizutani, S | 1 |
| Adjroud, O | 1 |
| Omer, S | 1 |
| Mulay, S | 1 |
| Cernacek, P | 1 |
| Varma, DR | 1 |
4 other studies available for thiorphan and Pregnancy
| Article | Year |
|---|---|
Routine antenatal anti-D prophylaxis--is the protection adequate?
Topics: Delivery, Obstetric; Female; Fetus; Humans; Infant, Newborn; Isoantibodies; Male; Pregnancy; Premedi | 2011 |
Possible involvement of placental peptidases that degrade gonadotropin-releasing hormone (GnRH) in the dynamic pattern of placental hCG secretion via GnRH degradation.
Topics: Adult; Antibodies, Blocking; Chorionic Villi; Chromatography, High Pressure Liquid; Edetic Acid; Fem | 2002 |
Peripheral excitatory effects of two enkephalinase inhibitors, acetorphan and thiorphan, and an enkephalin analogue, [D-Ala2-Met5]-enkephalinamide, on uterine motility in periparturient rats in vivo and in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; Naloxone; Narcotic Antago | 1995 |
Attenuation of renal effects of atrial natriuretic factor during rat pregnancy.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Female; Glomerular Filtrat | 1995 |