thiorphan has been researched along with Myocardial Infarction in 2 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Given that NEP and ACE metabolize angiotensin (Ang) and bradykinin (BK) peptides, we investigated the effects of NEP inhibition and combined NEP and ACE inhibition on Ang and BK levels in rats with myocardial infarction." | 7.70 | Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels. ( Anastasopoulos, F; Briscoe, TA; Campbell, DJ; Duncan, AM; James, GM; Kladis, A, 1999) |
| " Given that NEP and ACE metabolize angiotensin (Ang) and bradykinin (BK) peptides, we investigated the effects of NEP inhibition and combined NEP and ACE inhibition on Ang and BK levels in rats with myocardial infarction." | 3.70 | Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels. ( Anastasopoulos, F; Briscoe, TA; Campbell, DJ; Duncan, AM; James, GM; Kladis, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakano, A | 1 |
| Miura, T | 1 |
| Miki, T | 1 |
| Nozawa, Y | 1 |
| Ichikawa, Y | 1 |
| Ura, N | 1 |
| Shimamoto, K | 1 |
| Duncan, AM | 1 |
| James, GM | 1 |
| Anastasopoulos, F | 1 |
| Kladis, A | 1 |
| Briscoe, TA | 1 |
| Campbell, DJ | 1 |
2 other studies available for thiorphan and Myocardial Infarction
| Article | Year |
|---|---|
Effects of neutral endopeptidase 24.11 inhibition on myocardial infarct size and ischemic preconditioning in rabbits.
Topics: Animals; Blood Pressure; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Neprilys | 2002 |
Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Bradykinin; Cardiome | 1999 |