thiorphan has been researched along with Metastase in 2 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dorval, ED | 1 |
| Regimbeau, C | 1 |
| Gamelin, E | 1 |
| Picon, L | 1 |
| Bérard, H | 1 |
| Freyer, G | 1 |
| Rougier, P | 1 |
| Bugat, R | 1 |
| Droz, JP | 1 |
| Marty, M | 1 |
| Bleiberg, H | 1 |
| Mignard, D | 1 |
| Awad, L | 1 |
| Herait, P | 1 |
| Culine, S | 1 |
| Trillet-Lenoir, V | 1 |
2 trials available for thiorphan and Metastase
| Article | Year |
|---|---|
[Treatment of acute chemically induced diarrhea by inhibition of enkephalinase. Results of a pilot study].
Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; Combined Modality Therapy; Diarrhe | 1995 |
Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure. CPT-11 F205, F220, F221 and V222 study groups.
Topics: Adult; Aged; Antidiarrheals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Cam | 2000 |