thiorphan has been researched along with Kidney Failure, Chronic in 2 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dussaule, JC | 1 |
| Michel, C | 1 |
| Peraldi, MN | 1 |
| Lecomte, JM | 1 |
| Gros, C | 1 |
| Mignon, F | 1 |
| Ardaillou, R | 1 |
| Hand, MF | 1 |
| Haynes, WG | 1 |
| Webb, DJ | 1 |
2 trials available for thiorphan and Kidney Failure, Chronic
| Article | Year |
|---|---|
Inhibition of neutral endopeptidase stimulates renal sodium excretion in patients with chronic renal failure.
Topics: Adult; Aged; Aged, 80 and over; Atrial Natriuretic Factor; Cyclic GMP; Double-Blind Method; Female; | 1993 |
Reduced endogenous endothelin-1-mediated vascular tone in chronic renal failure.
Topics: Adult; Endothelin Receptor Antagonists; Endothelin-1; Female; Forearm; Glycopeptides; Humans; Inject | 1999 |