thiorphan has been researched along with Gastroenteritis in 8 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Gastroenteritis: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In our study group, the use of racecadotril did not improve the symptoms of diarrhea compared with standard rehydration therapy." | 9.14 | Use of racecadotril as outpatient treatment for acute gastroenteritis: a prospective, randomized, parallel study. ( Marañón, R; Miguez, C; Sánchez, C; Santos, M; Vázquez, P, 2009) |
| "Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea." | 9.14 | Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010) |
| "To assess racecadotril efficacy as an adjunct to oral rehydration solution, against oral rehydration solution alone or with placebo in childhood acute gastroenteritis." | 8.87 | Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis. ( Calatayud, GA; Castrellón, PG; Cézard, JP; Chéron, G; Garcia, JM; Lehert, P; Santos, M; Savitha, MR, 2011) |
| "In our study group, the use of racecadotril did not improve the symptoms of diarrhea compared with standard rehydration therapy." | 5.14 | Use of racecadotril as outpatient treatment for acute gastroenteritis: a prospective, randomized, parallel study. ( Marañón, R; Miguez, C; Sánchez, C; Santos, M; Vázquez, P, 2009) |
| "Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea." | 5.14 | Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010) |
| "To assess racecadotril efficacy as an adjunct to oral rehydration solution, against oral rehydration solution alone or with placebo in childhood acute gastroenteritis." | 4.87 | Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis. ( Calatayud, GA; Castrellón, PG; Cézard, JP; Chéron, G; Garcia, JM; Lehert, P; Santos, M; Savitha, MR, 2011) |
| "To summarize studies testing the efficacy and safety of racecadotril for treating children with acute gastroenteritis." | 4.84 | Systematic review: racecadotril in the treatment of acute diarrhoea in children. ( Chmielewska, A; Ruszczyński, M; Szajewska, H; Wieczorek, J, 2007) |
| "Racecadotril was more frequently used in France, and ondansetron was more frequently used in Switzerland." | 1.40 | Pediatric gastroenteritis in the emergency department: practice evaluation in Belgium, France, The Netherlands and Switzerland. ( Angoulvant, F; Gajdos, V; Julliand, S; Llor, J; Lorrot, M; Oostenbrink, R; Pelc, R; Redant, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pelc, R | 1 |
| Redant, S | 1 |
| Julliand, S | 1 |
| Llor, J | 1 |
| Lorrot, M | 1 |
| Oostenbrink, R | 1 |
| Gajdos, V | 1 |
| Angoulvant, F | 1 |
| Sáez, J | 2 |
| Cifuentes, L | 2 |
| Guarino, A | 1 |
| Buccigrossi, V | 1 |
| Armellino, C | 1 |
| Santos, M | 2 |
| Marañón, R | 1 |
| Miguez, C | 1 |
| Vázquez, P | 1 |
| Sánchez, C | 1 |
| Gallelli, L | 1 |
| Colosimo, M | 1 |
| Tolotta, GA | 1 |
| Falcone, D | 1 |
| Luberto, L | 1 |
| Curto, LS | 1 |
| Rende, P | 1 |
| Mazzei, F | 1 |
| Marigliano, NM | 1 |
| De Sarro, G | 1 |
| Cucchiara, S | 1 |
| Hofmann, R | 1 |
| Lehert, P | 1 |
| Chéron, G | 1 |
| Calatayud, GA | 1 |
| Cézard, JP | 1 |
| Castrellón, PG | 1 |
| Garcia, JM | 1 |
| Savitha, MR | 1 |
| Szajewska, H | 1 |
| Ruszczyński, M | 1 |
| Chmielewska, A | 1 |
| Wieczorek, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy, Safety and Cost-effectiveness Analysis of Impact of Racecadotril as an Adjunct in the Treatment of Acute Diarrhea in Mexican Children[NCT01153854] | Phase 3 | 454 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thiorphan and Gastroenteritis
| Article | Year |
|---|---|
Is racecadotril effective for acute diarrhea in children? -First update.
Topics: Acute Disease; Antidiarrheals; Child; Diarrhea; Gastroenteritis; Humans; Randomized Controlled Trial | 2015 |
Is racecadotril effective for acute diarrhea in children? -First update.
Topics: Acute Disease; Antidiarrheals; Child; Diarrhea; Gastroenteritis; Humans; Randomized Controlled Trial | 2015 |
Is racecadotril effective for acute diarrhea in children? -First update.
Topics: Acute Disease; Antidiarrheals; Child; Diarrhea; Gastroenteritis; Humans; Randomized Controlled Trial | 2015 |
Is racecadotril effective for acute diarrhea in children? -First update.
Topics: Acute Disease; Antidiarrheals; Child; Diarrhea; Gastroenteritis; Humans; Randomized Controlled Trial | 2015 |
Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis.
Topics: Adolescent; Adult; Antidiarrheals; Child; Combined Modality Therapy; Dehydration; Diarrhea; Feces; F | 2011 |
Systematic review: racecadotril in the treatment of acute diarrhoea in children.
Topics: Acute Disease; Antidiarrheals; Child, Preschool; Diarrhea; Female; Gastroenteritis; Humans; Infant; | 2007 |
2 trials available for thiorphan and Gastroenteritis
| Article | Year |
|---|---|
Use of racecadotril as outpatient treatment for acute gastroenteritis: a prospective, randomized, parallel study.
Topics: Acute Disease; Ambulatory Care; Antidiarrheals; Dehydration; Diarrhea; Drug Therapy, Combination; Em | 2009 |
Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Aging; Antidiarrheals; Cytochrome P-450 Enzyme System; Dehy | 2010 |
3 other studies available for thiorphan and Gastroenteritis
| Article | Year |
|---|---|
Pediatric gastroenteritis in the emergency department: practice evaluation in Belgium, France, The Netherlands and Switzerland.
Topics: Abdomen; Antidiarrheals; Antiemetics; Belgium; Blood Cell Count; Blood Gas Analysis; C-Reactive Prot | 2014 |
Colon in acute intestinal infection.
Topics: Acute Disease; Antidiarrheals; Caco-2 Cells; Colon; Diarrhea; Drug Evaluation, Preclinical; Gastroen | 2009 |
Remarks and questions on the article "Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes".
Topics: Aged; Antidiarrheals; Double-Blind Method; Female; Gastroenteritis; Homes for the Aged; Humans; Lope | 2010 |