Page last updated: 2024-10-26

thiorphan and Fibrosis

thiorphan has been researched along with Fibrosis in 2 studies

Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"Renoprotective potential of thiorphan (NEPi)/telmisartan (ARB) and thiorphan/Dize (ACE2 activator) combination therapies against the development of DN is primarily attributed to normalisation of RAS and NPS components and inhibition of pathological signalling related to inflammation, fibrosis, and apoptosis."3.91Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy. ( Gaikwad, AB; Malek, V; Sankrityayan, H; Sharma, N, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Malek, V2
Gaikwad, AB2
Sharma, N1
Sankrityayan, H1

Other Studies

2 other studies available for thiorphan and Fibrosis

ArticleYear
Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy.
    Cardiovascular research, 2019, 02-01, Volume: 115, Issue:2

    Topics: Acetylation; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Diabetes Mellitus, Experim

2019
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy.
    Life sciences, 2019, Mar-15, Volume: 221

    Topics: Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephr

2019