Page last updated: 2024-10-26

thiorphan and Cardiomyopathies

thiorphan has been researched along with Cardiomyopathies in 1 studies

Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Treatment with thiorphan (10 mg/kg i."1.28Effect of endopeptidase 24.11 inhibition in conscious cardiomyopathic hamsters. ( Blaine, EB; McGraw, DE; Smits, GJ; Trapani, AJ, 1990)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smits, GJ1
McGraw, DE1
Trapani, AJ1
Blaine, EB1

Other Studies

1 other study available for thiorphan and Cardiomyopathies

ArticleYear
Effect of endopeptidase 24.11 inhibition in conscious cardiomyopathic hamsters.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Cardiomyopathies; Cricetinae; Heart Failure; Male; Neprilysin; S

1990